Vitamin d physiology
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Vitamin D physiology is discussed in this module, including the vitamin D receptor and polymorphisms that can impact conditions like arthritis, metabolic syndrome, and multiple sclerosis. Different forms of vitamin D are also reviewed such as cholecalciferol, ergocalciferol, and their sources. Risk factors for vitamin D deficiency are examined like age, occupation, and clinical impacts.
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VITAMIN D
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https://www.blogger.com/blog/posts/2577104637130363155
Sunshine vitamin( Vitamin D)
This document discusses vitamin D, including its sources, functions, deficiency, recommended intake levels, associated health conditions, investigations, and management. Key points:
- Vitamin D is important for calcium absorption and bone health but many people are deficient due to lack of sun exposure and inadequate dietary intake.
- Deficiency can lead to bone diseases like rickets and osteomalacia as well as increased risk of cancers, cardiovascular disease, autoimmune disorders, and falls in older adults.
- At risk groups include breastfed infants, older adults, those with limited sun exposure or darker skin, obese individuals, and pregnant/postmenopausal women.
- Testing vitamin D levels helps diagnose deficiency as insufficient levels below
Vitamin D
The document discusses vitamin D, including its synthesis from sun exposure, its role in various bodily processes, and its potential health benefits. Key points include:
- Vitamin D is synthesized in the skin upon exposure to sunlight and can also be obtained through food and supplements. It plays an important role in bone and immune health.
- Vitamin D receptors are found throughout the body and vitamin D has been shown to regulate gene expression, turning genes on and off. This may explain its wide-ranging effects.
- Studies suggest vitamin D may help reduce the risk of various cancers, heart disease, diabetes, respiratory infections, autoimmune diseases, and mental health conditions like depression. Optimal vitamin D levels are important
Vit d is it the mericle vitamine
Vitamin D is an essential vitamin that must be metabolized to become biologically active. It plays an important role in calcium homeostasis, bone and muscle health, immune function, and the regulation of cell growth. The best indicator of vitamin D status is the measurement of 25-hydroxyvitamin D in the blood, as it reflects vitamin D from dietary intake and sunlight exposure. Low vitamin D levels have been associated with increased risk of various chronic diseases. Vitamin D deficiency can lead to impaired bone mineralization and increased fracture risk.
Vitamin D Deficiency Explained
Vitamin D deficiency will become more prevalent over the years as jobs will use more brain than "brawns". This is vitamin D explained!
Vit d
Vitamin D plays an important role in regulating calcium levels and bone health. It is also involved in insulin regulation and may protect against cancer, cardiovascular disease, and infections. Vitamin D deficiency can lead to rickets in children and osteomalacia in adults as well as increased risk of falls in older adults. Supplementation is recommended for those with inadequate sunlight exposure or dietary intake, with dosage depending on age.
Vit d and cv risks
This document summarizes research on vitamin D deficiency and cardiovascular risks. It discusses how vitamin D metabolism and mechanisms of action may impact cardiovascular outcomes. Several studies are cited showing associations between vitamin D deficiency and increased risks of hypertension, diabetes, heart disease, and mortality. However, the document also notes controversies in the research and calls for more rigorous randomized controlled trials. It outlines objectives and methods for a study examining vitamin D levels in patients with ischemic heart disease. The conclusion is that vitamin D levels correlate with cardiovascular disease and supplementation may help outcomes, but more clinical trials are still needed.
Vitamin D : A Comprehensive Presentation
This document discusses vitamin D, including its functions, sources, daily requirements, deficiency, toxicity, and management. Some key points:
- Vitamin D promotes calcium absorption and is important for bone health. Deficiency can cause rickets in children and osteomalacia in adults.
- Good dietary sources include fatty fish, fish liver oils, eggs, and dairy. Sun exposure also enables vitamin D production.
- Recommended daily intake is 10-20 micrograms for adults. Deficiency is managed with high dose vitamin D supplementation. Toxicity risks include excessive intake.
Recommended
VITAMIN D
All About Vitamin D
Follow me on SlideShare ,Follow on blogger.com and linkedIn...
https://www.slideshare.net/YashLodha11/vitamin-d-247723886/edit?src=slideview
https://www.linkedin.com/in/yash-lodha-047728211/
https://www.blogger.com/blog/posts/2577104637130363155
Sunshine vitamin( Vitamin D)
This document discusses vitamin D, including its sources, functions, deficiency, recommended intake levels, associated health conditions, investigations, and management. Key points:
- Vitamin D is important for calcium absorption and bone health but many people are deficient due to lack of sun exposure and inadequate dietary intake.
- Deficiency can lead to bone diseases like rickets and osteomalacia as well as increased risk of cancers, cardiovascular disease, autoimmune disorders, and falls in older adults.
- At risk groups include breastfed infants, older adults, those with limited sun exposure or darker skin, obese individuals, and pregnant/postmenopausal women.
- Testing vitamin D levels helps diagnose deficiency as insufficient levels below
Vitamin D
The document discusses vitamin D, including its synthesis from sun exposure, its role in various bodily processes, and its potential health benefits. Key points include:
- Vitamin D is synthesized in the skin upon exposure to sunlight and can also be obtained through food and supplements. It plays an important role in bone and immune health.
- Vitamin D receptors are found throughout the body and vitamin D has been shown to regulate gene expression, turning genes on and off. This may explain its wide-ranging effects.
- Studies suggest vitamin D may help reduce the risk of various cancers, heart disease, diabetes, respiratory infections, autoimmune diseases, and mental health conditions like depression. Optimal vitamin D levels are important
Vit d is it the mericle vitamine
Vitamin D is an essential vitamin that must be metabolized to become biologically active. It plays an important role in calcium homeostasis, bone and muscle health, immune function, and the regulation of cell growth. The best indicator of vitamin D status is the measurement of 25-hydroxyvitamin D in the blood, as it reflects vitamin D from dietary intake and sunlight exposure. Low vitamin D levels have been associated with increased risk of various chronic diseases. Vitamin D deficiency can lead to impaired bone mineralization and increased fracture risk.
Vitamin D Deficiency Explained
Vitamin D deficiency will become more prevalent over the years as jobs will use more brain than "brawns". This is vitamin D explained!
Vit d
Vitamin D plays an important role in regulating calcium levels and bone health. It is also involved in insulin regulation and may protect against cancer, cardiovascular disease, and infections. Vitamin D deficiency can lead to rickets in children and osteomalacia in adults as well as increased risk of falls in older adults. Supplementation is recommended for those with inadequate sunlight exposure or dietary intake, with dosage depending on age.
Vit d and cv risks
This document summarizes research on vitamin D deficiency and cardiovascular risks. It discusses how vitamin D metabolism and mechanisms of action may impact cardiovascular outcomes. Several studies are cited showing associations between vitamin D deficiency and increased risks of hypertension, diabetes, heart disease, and mortality. However, the document also notes controversies in the research and calls for more rigorous randomized controlled trials. It outlines objectives and methods for a study examining vitamin D levels in patients with ischemic heart disease. The conclusion is that vitamin D levels correlate with cardiovascular disease and supplementation may help outcomes, but more clinical trials are still needed.
Vitamin D : A Comprehensive Presentation
This document discusses vitamin D, including its functions, sources, daily requirements, deficiency, toxicity, and management. Some key points:
- Vitamin D promotes calcium absorption and is important for bone health. Deficiency can cause rickets in children and osteomalacia in adults.
- Good dietary sources include fatty fish, fish liver oils, eggs, and dairy. Sun exposure also enables vitamin D production.
- Recommended daily intake is 10-20 micrograms for adults. Deficiency is managed with high dose vitamin D supplementation. Toxicity risks include excessive intake.
ROLE OF VIT D IN FEMALE REPRODUCTION. PROF ABOUBAKR ELNASHAR
This document discusses the role of vitamin D in female reproduction. It begins by covering the production and metabolism of vitamin D, noting the two major forms and how they are converted in the liver and kidneys to their active form. It then discusses optimal vitamin D levels and biological activity, including genomic and non-genomic actions. The main section covers the role of vitamin D in female reproduction, such as its effects on sex hormones, ovarian reserve markers, endometriosis, PCOS, uterine fibroids, and IVF outcomes. It concludes that vitamin D is involved in regulating the female reproductive system and modulating gonadal function through its receptor, but more research is needed to fully understand its role in infertility treatment.
Vitamin D and disorders – hypo/ hypervitaminosis D
Vitamin D detailed information
and diseases associated with vitamin D deficiency and toxicity
covering about rickets and osteomalacia, information from Harrison's internal medicine and online resources like uptodate
Role of Vitamin D in Infertility
Vitamin D regulates estrogen biosynthesis through VDR’s
Direct regulation of the expression of the aromatase gene
Maintaining extracellular calcium homoeostasis
Vitamin D increases progesterone secretion by
Granulosa cell leutinisation – HOXA10 expression
Increased 3 β- HSD mRNA levels
Vitamin D increases placental sex steriod production
Regulates human chorionic expression
Secretion from human syncitiotrophoblasts (promoter- CYP19 )
VITAMIN D
Vitamin D deficiency is of concern now a days, it has important role in skeletal and non skeletal functions of the body. Good sunlight exposure, consumption of vitamin D rich foods, chemotherapy with vitamin D and supplements of vitamin D has shown positive effect on various non skeletal diseases like cancer, diabetes, diarrhoea, tuberculosis etc. Although Indians are blessed with ample sunlight, still 70 to 100% population is suffering from the vitamin D deficiency. Vitamin D deficiency is likely to play an important role in the very high prevalence of rickets, osteoporosis, cardiovascular diseases, diabetes, cancer and infections such as tuberculosis in India. Fortification of staple foods with vitamin D is the most viable population based strategy to achieve vitamin D sufficiency. Unfortunately, even in advanced countries like USA and Canada, food fortification strategies with vitamin D have been only partially effective and have largely failed to attain vitamin D sufficiency
Vitamin d and diabetes
Vitamin D plays an important role in maintaining bone and immune system health. The document discusses that vitamin D deficiency is common in Western countries due to limited sun exposure and may increase risk of conditions like diabetes. Maintaining adequate vitamin D levels through sun exposure, supplementation, or diet can help regulate blood sugar levels and support overall health.
Vitamin d deficiency
presentation of vitamin d deficiency, causes and prevalence
what is vitamin d deficiency and some of its main causes
Vitamin d deficiency
Vitamin D deficiency is a widespread problem globally and in India. It can cause rickets in children and bone problems in adults. The document discusses the causes, presentation, diagnosis, and treatment of vitamin D deficiency. Key points include that it is caused by low dietary intake and sun exposure, symptoms range from bone pain to rickets, screening involves vitamin D and calcium levels as well as imaging, and treatment consists of high dose vitamin D supplements and calcium for several weeks.
vitamin D deficiency
Vitamin D deficiency is common, affecting approximately 66% of the global population. It is defined as a serum 25-hydroxyvitamin D level below 20 ng/mL. Symptoms include bone and muscle pain. At-risk groups include those with dark skin, obesity, or malabsorption issues. Screening is recommended for high-risk individuals. Treatment involves oral vitamin D supplements of 50,000 IU weekly or 6000 IU daily to raise levels above 30 ng/mL. Maintenance doses of 800-1000 IU daily are used thereafter to prevent recurrence.
Dr Gerald Lewis Vitamin D Presentation
The document discusses vitamin D, describing it as essential for health and important for numerous functions in the body. It outlines that vitamin D helps absorb calcium for strong bones and teeth, and supports immune function, mental health, and may lower risks of various diseases. It recommends getting vitamin D through moderate sun exposure or dietary supplements, and describes an optimal vitamin D blood level range.
Vitamin d deficiency – myths & facts
Vitamin D deficiency is highly prevalent around the world, including in India where studies show 76-100% of populations are deficient or insufficient. Multiple factors contribute to low vitamin D levels, including limited sun exposure, skin pigmentation, traditional clothing, air pollution, and dietary habits. While sunlight exposure is important for vitamin D synthesis, too little or too much can be problematic. Maintaining optimal vitamin D levels of 30-50 ng/ml through balanced sun exposure and dietary sources is important for overall health.
Vitamin d deficiency in children
Vitamin D deficiency remains the most common cause of rickets in children. Breastfed infants rely on sunlight or supplements for vitamin D as breast milk is low in vitamin D. Cutaneous vitamin D synthesis can be limited by winter sunlight, sun avoidance, skin pigmentation, and cultural practices. Vitamin D deficiency is now considered a global pandemic with implications for skeletal and overall health in young children. Oral or intramuscular high dose vitamin D supplements are effective treatments for nutritional vitamin D deficiency in children.
Whats All The Fuss About Vitamin D
This document discusses vitamin D deficiency in Australia. It notes that 75% of Brisbane residents are vitamin D deficient, and links low vitamin D levels to increased rates of osteoporosis and related diseases. While sun exposure is needed to produce vitamin D, Australia has high skin cancer rates due to sun exposure. The document examines the challenges of obtaining adequate vitamin D levels through diet and supplements while still practicing sun protection. It emphasizes the importance of monitoring vitamin D levels, especially in high risk groups.
Metabolic bone diseases ( Rickets / Osteomalacia / Hyperparathyroidism)
It's a slide show that has been prepared to show how to treat osteomalacia/rickets in actual clinical setting. Lastly it has a summary of hyperparathyroidism.
Eggs: Solutions to Vitamin D deficiency - Knowledge Day 2016
Dr. Linda Browning discusses vitamin D deficiency as a global health issue and proposes that eggs can be a solution. At the end of the 19th century, rickets afflicted 90% of dead children in cities due to lack of vitamin D. While vitamin D is important for calcium absorption and bone health, deficiency is also linked to increased risk of cancer, cardiovascular disease, and autoimmune disorders. The document outlines ways to increase vitamin D content in eggs through supplemental feeding of hens. Enriched eggs could help address widespread vitamin D inadequacy globally by providing a rich, affordable source through regular consumption.
Vitamin D And Health Presentation Z 8 05 09
The document summarizes recent research on vitamin D and its links to various chronic diseases. It finds that vitamin D is important for calcium absorption and other body functions, and recommends getting adequate vitamin D through sunlight exposure, dietary sources like fatty fish and fortified foods, and supplements if needed. Getting enough vitamin D may help reduce the risk of diseases like cancer, heart disease, and osteoporosis.
Vitamin D deficiency
Vitamin D deficiency can result from inadequate sunlight exposure, low dietary intake, or impairments in vitamin D metabolism. It causes rickets in children as their bones fail to properly mineralize, while in adults it causes osteomalacia marked by bone pain and fractures. Risk factors include liver or digestive diseases, certain drugs, and genetic mutations impacting vitamin D metabolism. Osteoporosis involves low bone density and increased fracture risk related to aging and declining estrogen levels along with impaired vitamin D function.
Vitamin D in Pregnancy & Lactation by Prof A Elbareg
This document discusses vitamin D metabolism and requirements during pregnancy and lactation. It covers:
1) Vitamin D metabolism, including sources, conversion to active forms in the liver and kidneys, and role of vitamin D binding protein.
2) Increased vitamin D levels and requirements during pregnancy to support fetal development. Supplementation guidelines recommend 1500-2000 IU/day to maintain optimal levels.
3) Associations between vitamin D deficiency and gestational diabetes and preeclampsia, though the evidence is mixed and relationships may be indirect. Maintaining sufficient vitamin D status may help reduce risks of complications.
Vitamin D by Farshid Mokhberi
Vitamin D comes from two sources and exists in several forms, with the main forms being vitamins D2 and D3. It plays a key role in calcium absorption and bone health. Testing for 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels can determine vitamin D status and identify deficiencies or toxicities. A blood sample is needed for testing, with results used to guide supplementation and treatment of bone diseases.
Vitamin d insufficiency and deficiency in children and adolescents
Vitamin D insufficiency and deficiency can occur in children and adolescents. The document discusses the forms and pathways of vitamin D in the body. Risk factors for deficiency include dark skin, limited sun exposure, exclusive breastfeeding, obesity, and genetic disorders. Deficiency can lead to rickets in children or osteomalacia. Diagnosis is made by measuring 25-hydroxyvitamin D levels in the blood. Treatment involves vitamin D supplementation, with dosage depending on age and severity of deficiency. Monitoring of vitamin D levels is important during and after treatment.
Vitamin D Presentation
This document provides an overview of vitamin D, including its chemical nature, sources, importance, deficiency, and related diseases. It discusses vitamin D's role in bone health and calcium absorption. It also covers rickets and osteomalacia, bone diseases caused by vitamin D deficiency, and their symptoms, causes, prevalence worldwide, and treatment options. The document concludes by emphasizing the importance of obtaining sufficient vitamin D through sun exposure, diet, and supplements to prevent deficiency-related diseases.
Vitamin d- Dr.Sohail
The document provides an overview of vitamin D, including its history, sources, functions, deficiency, testing, and effects on bones and teeth. Vitamin D is important for calcium absorption and bone mineralization, and deficiency can lead to conditions like rickets and osteomalacia, causing bone deformities and increased risk of fractures. The document discusses various forms of vitamin D, recommended intake levels, biomarkers used to indicate status, laboratory testing methods, and dental considerations related to vitamin D deficiency.
vitamin D - dental applications
This document provides information on vitamin D, including its history, forms, sources, functions, deficiency, testing, and role in dental health. It discusses the key points that vitamin D is important for calcium absorption and bone mineralization, sources include exposure to sunlight and dietary intake of oily fish, eggs, and fortified foods. Vitamin D deficiency can lead to metabolic bone diseases like rickets in children and osteomalacia in adults, causing bone pain and deformities. Biomarkers and tests are used to diagnose and monitor vitamin D levels.
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ROLE OF VIT D IN FEMALE REPRODUCTION. PROF ABOUBAKR ELNASHAR
This document discusses the role of vitamin D in female reproduction. It begins by covering the production and metabolism of vitamin D, noting the two major forms and how they are converted in the liver and kidneys to their active form. It then discusses optimal vitamin D levels and biological activity, including genomic and non-genomic actions. The main section covers the role of vitamin D in female reproduction, such as its effects on sex hormones, ovarian reserve markers, endometriosis, PCOS, uterine fibroids, and IVF outcomes. It concludes that vitamin D is involved in regulating the female reproductive system and modulating gonadal function through its receptor, but more research is needed to fully understand its role in infertility treatment.
Vitamin D and disorders – hypo/ hypervitaminosis D
Vitamin D detailed information
and diseases associated with vitamin D deficiency and toxicity
covering about rickets and osteomalacia, information from Harrison's internal medicine and online resources like uptodate
Role of Vitamin D in Infertility
Vitamin D regulates estrogen biosynthesis through VDR’s
Direct regulation of the expression of the aromatase gene
Maintaining extracellular calcium homoeostasis
Vitamin D increases progesterone secretion by
Granulosa cell leutinisation – HOXA10 expression
Increased 3 β- HSD mRNA levels
Vitamin D increases placental sex steriod production
Regulates human chorionic expression
Secretion from human syncitiotrophoblasts (promoter- CYP19 )
VITAMIN D
Vitamin D deficiency is of concern now a days, it has important role in skeletal and non skeletal functions of the body. Good sunlight exposure, consumption of vitamin D rich foods, chemotherapy with vitamin D and supplements of vitamin D has shown positive effect on various non skeletal diseases like cancer, diabetes, diarrhoea, tuberculosis etc. Although Indians are blessed with ample sunlight, still 70 to 100% population is suffering from the vitamin D deficiency. Vitamin D deficiency is likely to play an important role in the very high prevalence of rickets, osteoporosis, cardiovascular diseases, diabetes, cancer and infections such as tuberculosis in India. Fortification of staple foods with vitamin D is the most viable population based strategy to achieve vitamin D sufficiency. Unfortunately, even in advanced countries like USA and Canada, food fortification strategies with vitamin D have been only partially effective and have largely failed to attain vitamin D sufficiency
Vitamin d and diabetes
Vitamin D plays an important role in maintaining bone and immune system health. The document discusses that vitamin D deficiency is common in Western countries due to limited sun exposure and may increase risk of conditions like diabetes. Maintaining adequate vitamin D levels through sun exposure, supplementation, or diet can help regulate blood sugar levels and support overall health.
Vitamin d deficiency
presentation of vitamin d deficiency, causes and prevalence
what is vitamin d deficiency and some of its main causes
Vitamin d deficiency
Vitamin D deficiency is a widespread problem globally and in India. It can cause rickets in children and bone problems in adults. The document discusses the causes, presentation, diagnosis, and treatment of vitamin D deficiency. Key points include that it is caused by low dietary intake and sun exposure, symptoms range from bone pain to rickets, screening involves vitamin D and calcium levels as well as imaging, and treatment consists of high dose vitamin D supplements and calcium for several weeks.
vitamin D deficiency
Vitamin D deficiency is common, affecting approximately 66% of the global population. It is defined as a serum 25-hydroxyvitamin D level below 20 ng/mL. Symptoms include bone and muscle pain. At-risk groups include those with dark skin, obesity, or malabsorption issues. Screening is recommended for high-risk individuals. Treatment involves oral vitamin D supplements of 50,000 IU weekly or 6000 IU daily to raise levels above 30 ng/mL. Maintenance doses of 800-1000 IU daily are used thereafter to prevent recurrence.
Dr Gerald Lewis Vitamin D Presentation
The document discusses vitamin D, describing it as essential for health and important for numerous functions in the body. It outlines that vitamin D helps absorb calcium for strong bones and teeth, and supports immune function, mental health, and may lower risks of various diseases. It recommends getting vitamin D through moderate sun exposure or dietary supplements, and describes an optimal vitamin D blood level range.
Vitamin d deficiency – myths & facts
Vitamin D deficiency is highly prevalent around the world, including in India where studies show 76-100% of populations are deficient or insufficient. Multiple factors contribute to low vitamin D levels, including limited sun exposure, skin pigmentation, traditional clothing, air pollution, and dietary habits. While sunlight exposure is important for vitamin D synthesis, too little or too much can be problematic. Maintaining optimal vitamin D levels of 30-50 ng/ml through balanced sun exposure and dietary sources is important for overall health.
Vitamin d deficiency in children
Vitamin D deficiency remains the most common cause of rickets in children. Breastfed infants rely on sunlight or supplements for vitamin D as breast milk is low in vitamin D. Cutaneous vitamin D synthesis can be limited by winter sunlight, sun avoidance, skin pigmentation, and cultural practices. Vitamin D deficiency is now considered a global pandemic with implications for skeletal and overall health in young children. Oral or intramuscular high dose vitamin D supplements are effective treatments for nutritional vitamin D deficiency in children.
Whats All The Fuss About Vitamin D
This document discusses vitamin D deficiency in Australia. It notes that 75% of Brisbane residents are vitamin D deficient, and links low vitamin D levels to increased rates of osteoporosis and related diseases. While sun exposure is needed to produce vitamin D, Australia has high skin cancer rates due to sun exposure. The document examines the challenges of obtaining adequate vitamin D levels through diet and supplements while still practicing sun protection. It emphasizes the importance of monitoring vitamin D levels, especially in high risk groups.
Metabolic bone diseases ( Rickets / Osteomalacia / Hyperparathyroidism)
It's a slide show that has been prepared to show how to treat osteomalacia/rickets in actual clinical setting. Lastly it has a summary of hyperparathyroidism.
Eggs: Solutions to Vitamin D deficiency - Knowledge Day 2016
Dr. Linda Browning discusses vitamin D deficiency as a global health issue and proposes that eggs can be a solution. At the end of the 19th century, rickets afflicted 90% of dead children in cities due to lack of vitamin D. While vitamin D is important for calcium absorption and bone health, deficiency is also linked to increased risk of cancer, cardiovascular disease, and autoimmune disorders. The document outlines ways to increase vitamin D content in eggs through supplemental feeding of hens. Enriched eggs could help address widespread vitamin D inadequacy globally by providing a rich, affordable source through regular consumption.
Vitamin D And Health Presentation Z 8 05 09
The document summarizes recent research on vitamin D and its links to various chronic diseases. It finds that vitamin D is important for calcium absorption and other body functions, and recommends getting adequate vitamin D through sunlight exposure, dietary sources like fatty fish and fortified foods, and supplements if needed. Getting enough vitamin D may help reduce the risk of diseases like cancer, heart disease, and osteoporosis.
Vitamin D deficiency
Vitamin D deficiency can result from inadequate sunlight exposure, low dietary intake, or impairments in vitamin D metabolism. It causes rickets in children as their bones fail to properly mineralize, while in adults it causes osteomalacia marked by bone pain and fractures. Risk factors include liver or digestive diseases, certain drugs, and genetic mutations impacting vitamin D metabolism. Osteoporosis involves low bone density and increased fracture risk related to aging and declining estrogen levels along with impaired vitamin D function.
Vitamin D in Pregnancy & Lactation by Prof A Elbareg
This document discusses vitamin D metabolism and requirements during pregnancy and lactation. It covers:
1) Vitamin D metabolism, including sources, conversion to active forms in the liver and kidneys, and role of vitamin D binding protein.
2) Increased vitamin D levels and requirements during pregnancy to support fetal development. Supplementation guidelines recommend 1500-2000 IU/day to maintain optimal levels.
3) Associations between vitamin D deficiency and gestational diabetes and preeclampsia, though the evidence is mixed and relationships may be indirect. Maintaining sufficient vitamin D status may help reduce risks of complications.
Vitamin D by Farshid Mokhberi
Vitamin D comes from two sources and exists in several forms, with the main forms being vitamins D2 and D3. It plays a key role in calcium absorption and bone health. Testing for 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels can determine vitamin D status and identify deficiencies or toxicities. A blood sample is needed for testing, with results used to guide supplementation and treatment of bone diseases.
Vitamin d insufficiency and deficiency in children and adolescents
Vitamin D insufficiency and deficiency can occur in children and adolescents. The document discusses the forms and pathways of vitamin D in the body. Risk factors for deficiency include dark skin, limited sun exposure, exclusive breastfeeding, obesity, and genetic disorders. Deficiency can lead to rickets in children or osteomalacia. Diagnosis is made by measuring 25-hydroxyvitamin D levels in the blood. Treatment involves vitamin D supplementation, with dosage depending on age and severity of deficiency. Monitoring of vitamin D levels is important during and after treatment.
Vitamin D Presentation
This document provides an overview of vitamin D, including its chemical nature, sources, importance, deficiency, and related diseases. It discusses vitamin D's role in bone health and calcium absorption. It also covers rickets and osteomalacia, bone diseases caused by vitamin D deficiency, and their symptoms, causes, prevalence worldwide, and treatment options. The document concludes by emphasizing the importance of obtaining sufficient vitamin D through sun exposure, diet, and supplements to prevent deficiency-related diseases.
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ROLE OF VIT D IN FEMALE REPRODUCTION. PROF ABOUBAKR ELNASHAR
ROLE OF VIT D IN FEMALE REPRODUCTION. PROF ABOUBAKR ELNASHAR
Vitamin D and disorders – hypo/ hypervitaminosis D
Vitamin D and disorders – hypo/ hypervitaminosis D
Metabolic bone diseases ( Rickets / Osteomalacia / Hyperparathyroidism)
Metabolic bone diseases ( Rickets / Osteomalacia / Hyperparathyroidism)
Eggs: Solutions to Vitamin D deficiency - Knowledge Day 2016
Eggs: Solutions to Vitamin D deficiency - Knowledge Day 2016
Vitamin D in Pregnancy & Lactation by Prof A Elbareg
Vitamin D in Pregnancy & Lactation by Prof A Elbareg
Vitamin d insufficiency and deficiency in children and adolescents
Vitamin d insufficiency and deficiency in children and adolescents
Similar to Vitamin d physiology
Vitamin d- Dr.Sohail
The document provides an overview of vitamin D, including its history, sources, functions, deficiency, testing, and effects on bones and teeth. Vitamin D is important for calcium absorption and bone mineralization, and deficiency can lead to conditions like rickets and osteomalacia, causing bone deformities and increased risk of fractures. The document discusses various forms of vitamin D, recommended intake levels, biomarkers used to indicate status, laboratory testing methods, and dental considerations related to vitamin D deficiency.
vitamin D - dental applications
This document provides information on vitamin D, including its history, forms, sources, functions, deficiency, testing, and role in dental health. It discusses the key points that vitamin D is important for calcium absorption and bone mineralization, sources include exposure to sunlight and dietary intake of oily fish, eggs, and fortified foods. Vitamin D deficiency can lead to metabolic bone diseases like rickets in children and osteomalacia in adults, causing bone pain and deformities. Biomarkers and tests are used to diagnose and monitor vitamin D levels.
The global epidemic and the d lightful vitamin
Vitamin D deficiency is a global epidemic affecting over 1 billion people worldwide. The document discusses how despite plentiful sunlight, 78% of UAE residents have vitamin D deficiency due to indoor lifestyles and clothing habits. It also summarizes that three quarters of US teens and adults are deficient in vitamin D and this is linked to diseases like rickets, osteomalacia, heart disease, cancers, diabetes and more. The document advocates for vitamin D supplementation and sensible sun exposure to help regulate over 2000 genes and 160 metabolic pathways influenced by vitamin D.
Vitamin d-deficiency
Vitamin D deficiency is common worldwide and can cause many health issues. It is involved in calcium absorption and bone health. Deficiency leads to osteomalacia and rickets in children, and increases risk of fractures in adults. It may also play roles in cardiovascular disease, diabetes, cancer prevention, autoimmune disease, pregnancy complications, muscle weakness, and mortality. Treatment involves dietary sources of vitamin D, supplementation, and sunlight exposure.
Asthma, allergy and respiratory infections: the vitamin D hypothesis
The document discusses the relationship between vitamin D and respiratory conditions like asthma. It suggests that vitamin D deficiency has been associated with increased risk of respiratory infections and asthma exacerbations. This may be because vitamin D plays important roles in immune function and lung development. The document reviews studies showing links between low vitamin D levels and higher risks of respiratory infections, asthma symptoms, and impaired lung function. However, the relationships are complex and not fully understood, as some studies have also linked high vitamin D supplementation to increased asthma risk. More research is still needed to clarify the roles and optimal levels of vitamin D.
Rickets
Rickets is a disease of growing bones caused by lack of vitamin D and calcium. It most commonly affects children aged 6 months to 2 years who are breastfed but not supplemented. Symptoms include bone pain, bowed legs, and fractures. Diagnosis involves blood tests showing low calcium and vitamin D levels and characteristic bone changes on x-rays. Treatment involves high dose vitamin D and calcium supplementation. Long term consequences can include permanent bone deformities if left untreated.
Vitamin d and neurological diseases
Vitamin D is essential for neurological health. It is synthesized in the skin upon sun exposure and supports calcium absorption and bone health. Low vitamin D levels are common and associated with increased risk of multiple sclerosis (MS), where each 10 nmol/L increase in vitamin D is associated with lower odds of MS lesions and relapses. For other conditions like Parkinson's and Alzheimer's, low vitamin D is linked to higher risk, though the mechanisms are still being explored. Screening and supplementation can help maintain sufficient vitamin D levels to support neurological and overall health.
Vitamin d deficiency in children
This document discusses vitamin D deficiency in children. It covers vitamin D metabolism, sources, benefits, and deficiency. Regarding deficiency, it defines it as a 25-hydroxyvitamin D level below 20 ng/mL. Common causes include lack of sun exposure and low dietary intake. Signs and symptoms can include bone pain, muscle weakness, fatigue, and bone deformities like rickets. Laboratory findings show low vitamin D levels while radiological findings reveal issues with bone mineralization. Prevention focuses on supplementation and treatment involves higher dose vitamin D, like 50,000 IU weekly for 8-12 weeks.
Vitamin D deficiency in children
This document discusses vitamin D deficiency in children. It covers vitamin D metabolism, sources, benefits, and deficiency. Regarding deficiency, it defines it as a 25-hydroxyvitamin D level below 20 ng/mL. Common causes include lack of sun exposure and low dietary intake. Signs and symptoms can include bone pain, muscle weakness, fatigue, and bone deformities like rickets. Laboratory findings show low vitamin D levels while radiological findings reveal issues with bone mineralization. Prevention focuses on supplementation and treatment involves higher dose vitamin D, like 50,000 IU weekly for 8-12 weeks.
Vitamin D: The Sunshine vitamin
Vitamin D is a fat-soluble vitamin that is produced in the body after exposure to sunlight. It has two major forms, vitamin D3 and D2. Vitamin D acts as a hormone by binding to vitamin D receptors in tissues like bone and intestine. It helps regulate calcium and phosphate absorption and bone remodeling. Deficiencies can lead to rickets in children or osteomalacia in adults, characterized by soft, deformed bones and fractures. Sources include sunlight, fatty fish, and fortified foods. Toxicity from excess vitamin D causes hypercalcemia.
Vitamin D - Health Issues
This document discusses vitamin D deficiency as a global health problem, definitions of vitamin D deficiency, sources and requirements of vitamin D, and consequences of vitamin D deficiency such as osteomalacia and rickets. It provides treatment recommendations for vitamin D deficiency in adults, including initiating treatment at vitamin D levels below 20 ng/mL, recommended dosages of 6000 IU/day, duration of treatment of 4-12 weeks, and follow-up maintenance dosages. Higher dosages may be needed for certain high-risk individuals. Oral cholecalciferol is the preferred route of treatment.
Shafei vit.d
Vitamin D has important roles in bone health, immune function, cell growth and many other physiological processes. It is produced in the skin upon exposure to sunlight, but can also be obtained through dietary sources. Deficiency is associated with increased risk of various diseases such as cancer, cardiovascular disease, diabetes and autoimmune disorders. Maintaining sufficient vitamin D levels through sunlight exposure and/or supplementation may provide protective health benefits.
Vitamina D ed Asma - Prof. Boner Attilio Università di Verona
1) Several studies show high rates of vitamin D deficiency and insufficiency among children with asthma. Low vitamin D levels are associated with worse asthma control, including increased exacerbations and hospitalizations.
2) Observational studies link higher maternal vitamin D intake during pregnancy to lower rates of wheezing and asthma in offspring. However, the evidence for a causal relationship is still insufficient.
3) Maintaining adequate vitamin D levels, especially during pregnancy and childhood, may help reduce asthma risk and severity by supporting lung development and function. Further research is still needed.
Lecce vitamina d 8.4.2014
Vitamin D deficiency is common in obesity and is both a consequence of and risk factor for several metabolic conditions. Lower vitamin D levels are seen in obese individuals due to sequestration in fat tissue and lack of sun exposure. Vitamin D deficiency is associated with metabolic syndrome, hypertension, diabetes, high cholesterol, and increased cardiovascular risk. Supplementation may help treat vitamin D deficiency, but obesity also needs to be addressed to fully resolve the underlying causes.
Use of vitamin d in non bone diseases
This document discusses the use of vitamin D in preventing and treating non-bone diseases. It begins with an introduction and covers topics like immunomodulation related to allergy, fetal development, and the prevention and modification of diseases like asthma, COPD, allergic rhinitis, atopic dermatitis, and food allergy. It also briefly mentions autoimmunity and other diseases. The document provides information on vitamin D synthesis and metabolism and cites several studies on vitamin D levels in different populations and its effects. It concludes with a discussion of vitamin D's immunomodulatory effects in relation to allergy.
Aya
Vitamin D has increasingly been recognized for its importance beyond bone health. It may help prevent over 100 disorders ranging from cancer to diabetes to depression. Many people have deficient or insufficient vitamin D levels. While sunlight is the best source, factors like sunscreen use, age, and skin pigmentation can reduce natural vitamin D production. Supplementation is often recommended. Vitamin D is involved in processes throughout the body like immune function, cell growth, neuromuscular and immune functioning. Low levels are linked to higher risk of diseases like cancer, heart disease, diabetes, and autoimmune conditions like multiple sclerosis. Testing levels and supplementing to reach optimal levels may provide significant health benefits.
VIT D3 seminar
Vitamin D is a fat-soluble vitamin derived from cholesterol that functions as a steroid hormone. It is present in the skin in an inactive form, 7-dehydrocholesterol, and is converted to the active form calciferol when the skin is exposed to sunlight. The active form of vitamin D binds to vitamin D receptors in target cells and acts as a transcription factor that modulates gene expression involved in calcium absorption and bone health. Risk factors for vitamin D deficiency include inadequate sun exposure, skin pigmentation, obesity, and certain medical conditions or medications. Vitamin D deficiency can lead to rickets in children and osteomalacia in adults, and has also been associated with increased risk of diabetes, preecl
Vitamin D in health and disease
A brief review about the role of vitamin D in health and disease. Most of the content in these slides were taken from another author with some editing to custom it for the purpose of general physician workshop scientific material. Some figures were our own data in our hospital
Vit D ARDS
Vitamin D deficiency ( plasma 25(OH)D levels
<50 nmol/L)(20 ng/ml) was ubiquitous in patients with ARDS and
present in the vast majority of patients at risk of
developing ARDS following oesophagectomy.
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Vitamin d physiology
- 2. Module 1
- 3. Vitamin D Physiology Dr. Samar Abbas Jaffri MBBS, MRCP(UK), FCPS(Med), FRCP(Edin) Consultant Physician & Assistant Professor Department of Medicine, Liaquat National Hospital & Medical College, Karachi
- 5. Physiology
- 7. VDR Polymorphism VDR gene polymorphism restricts anti- imflammatory action of vitamin D by altering the 1, 25(OH)2 D3 binding sites Arthritis: rs10735810, rs1544410, rs7975232, and rs731236 associated with the onset of arthritis Metabolic Syndrome: rs7975232, and rs1544410 variants associated Fokl variant is associated with elevated circulating FFA and Adipose tissue IR Multiple sclerosis: TaqI, Bsml polymorphism increase susceptibility; ApaI decreases risk Cirrhosis: ApaI, TaqI and BsmI associated with severity; FokI possibly protective
- 9. Different Forms of Vitamin D Cholecalciferol Ergocalciferol Vitamin D3 Vitamin D2 Animal source Plant source Naturally derived supplement Synthetic supplement Significantly increases Vitamin D levels in body Moderately increases Vitamin D levels in body Optimal for bone and immune support Suitable alternative for vegetarians 5 subtypes – Vitamin D1, D2, D3, D4 & D5
- 13. Epidemiology
- 14. Age & Occupation
- 15. Risk Factors
- 16. Clinical Impact