This document discusses boosting compute performance for virtual machines (VMs) in an OpenStack cloud. It covers VM placement in OpenStack, which impacts both VM performance and efficient resource usage. Specifically, it focuses on NUMA-aware scheduling and CPU pinning to improve performance for high-performance workloads. A demo is provided of reserving dedicated CPU cores for host processes and VMs in OpenStack Kilo to enable these techniques. Benchmark results show performance improvements for VMs using these methods.