The document discusses production planning and control (PPC) in the pharmaceutical manufacturing industry. It highlights some of the key challenges in PPC, including combining functions, follow-up, and re-planning. It also discusses factors that affect PPC, such as market forecasts, sales orders, standard process sheets, and load charts. Master production schedules are the main driver for material requirements planning and production scheduling. Frequent changes to schedules can create system "nervousness" and impact material availability, delivery dates, and re-planning activities. Effective PPC aims to optimize resource utilization, ensure quality delivery, and maximize profits.