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Tuberculosis
PRESENTED BY
ANISHA B
40050005
Introduction:
 Tuberculosis (TB) is one of the most prevalent
infections of human beings and contributes
considerably to illness and death around the world
.It is spread by inhaling tiny droplets of saliva from
the coughs or sneezes of an infected person.It is a
slowly spreading, chronic, granulomatous bacterial
infection, characterized by gradual weight loss.
Tuberculosis
 Causative agent:
Mycobacterium tuberculosis
 Site of infection:
Pulmonary alveoli
 Immune response:
Cell mediated immunity
Etiology
Mycobacterium tuberculosis
Droplet nuclei (caughing,sneezing,
laughing)
Exposure to TB
Pathophysiology
Tuberculosis : The tubercle bacilli establish
infection in the lungs after they are carried in
droplets small enough (5 to 10 microns) to
reach the alveolar spaces. If the defense system
of the host fails to eliminate the infection, the
bacilli proliferate inside alveolar macrophages
and eventually kill the cells.
Pathophysiology
Pathophysiology
Symptoms
Treatment
Multidrug therapy
 Multiple drug therapy to treat TB means taking
several different antitubercular drugs at the same
time.
 The standard treatment is to take
isoniazid,rifampin,ethambutol,and pyrazinamide
for two months. Treatment is then continued for
at least 4 months with fewer medications.
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Tuberculosis,its causative agent,mode of spread,symptoms and treatment .pptx