1. Triage systems categorize trauma patients based on the urgency of their injuries to prioritize care. Mass casualty incidents require prioritizing those most likely to survive when resources are insufficient.
2. Total parenteral nutrition (TPN) provides all nutritional needs intravenously, bypassing the gastrointestinal tract. It requires a central venous catheter and careful monitoring to prevent complications.
3. Burns are classified by degree of skin layer involvement and percentage of total body surface area burned. Major burns require specialized burn unit care for infections, shock, and complications affecting multiple organ systems.
Burn is coagulative necrosis of the skin’s tissues, usually caused by excessive heat
Excess heat causes rapid protein denaturation and cell damage
Wet heat (scald) travels more rapidly into tissue than dry heat (flame)
A surface temperature of over 60˚C produces immediate cell death as well as vessel thrombosis
The dead skin tissue is known as Eschar
it consist definition, types of burn, its cause, scales to measure degree of burn, first aid management and supportive management along with rehabilitation therapy.
An extensive presentation on the anatomy, physiology, classification and management of various degree of burns. I made this in the final year of my Anesthesia residency and I have tried to add the maximum information as possible to make this a useful source for anyone.
Burn is coagulative necrosis of the skin’s tissues, usually caused by excessive heat
Excess heat causes rapid protein denaturation and cell damage
Wet heat (scald) travels more rapidly into tissue than dry heat (flame)
A surface temperature of over 60˚C produces immediate cell death as well as vessel thrombosis
The dead skin tissue is known as Eschar
it consist definition, types of burn, its cause, scales to measure degree of burn, first aid management and supportive management along with rehabilitation therapy.
An extensive presentation on the anatomy, physiology, classification and management of various degree of burns. I made this in the final year of my Anesthesia residency and I have tried to add the maximum information as possible to make this a useful source for anyone.
This topic is oriented mainly on the Bailey & Love - 26th edition.
This will be of immense help for the MBBS - Students for the Theory as well as Clinical application.
medical surgical nursing , nursing management of burn patients, it includes definition, classification of burn injury, clinical manifestaion, assessment of burn injury , management of patient with burn, care given to the patient.
This topic is oriented mainly on the Bailey & Love - 26th edition.
This will be of immense help for the MBBS - Students for the Theory as well as Clinical application.
medical surgical nursing , nursing management of burn patients, it includes definition, classification of burn injury, clinical manifestaion, assessment of burn injury , management of patient with burn, care given to the patient.
Burn and burn rehabilitation includes patho physiology of burn, types or causes of burn, acute management of burn, rehabilitation of burn, surgical management, grafting, complication of burn etc.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
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Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
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Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
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2. Triage
• Triage is a system to attend trauma patients, formulated by Committee of
Trauma of the American College of Surgeons. There are several
commercial systems available to label patients so emergency personnel can
see at a glance the scale of the incident. The key is to divide patients by
the urgency of care/transfer to hospital
Types of Triage System
• Multiple casualties: Staff and facilities are sufficient but priority is given to
life-threatening injuries.
• Mass casualties: Staff and facilities are not sufficient to manage. Here
those who are likely to have highest chance of survival are given priority.
3. • Goals
• Identify life-threatening
conditions.
• Decide and implement
appropriate treatment to the area
of trauma.
• First think to salvage the life, then
think to salvage the limb.
• Rapid assessment, rapid
resuscitation, rapid stabilisation.
• Optimum, complete care.
• Transport efficiently to higher
trauma centre
4. Management (A,B,C,D,E,F)
I. Primary Management
• Airway management (blocked by
food, vomitus, clot, fallen
tongue).
• Breathing
• Circulation.
• Disability and level of
consciousness assessment by
Glasgow coma scale.
• Exposure of the patient from
head to toe for final assessment.
• Fingers and tubes: Finger
evaluation, Foley’s
catheterisation.
5.
6. Total Parenteral Nutrition
• Total parenteral nutrition (TPN) is
a method of feeding that
bypasses the gastrointestinal
tract
• All nutritional requirements are
given only through intravenous
route
• TPN is given through central vein
and not through a peripheral
vein.
• Central catheter through the
subclavian/internal jugular vein
where the tip of venous catheter
is at distal part of superior vena
cava.
7. Goals, Factors and Assessment in TPN
• To decrease adverse effects of
catabolism;
• To maintain glycogen reserve in
cardiac and respiratory muscles.
• To maintain acid, base and
electrolyte metabolism.
• Age, premorbid state, muscle mass,
weight, serum albumin should be
assessed.
8. • Requirement
• 1. Fluid requirement is assessed by—1500 ml for 20 kg weight + 20
ml/kg for additional weight.
• 2. Energy needed is calculated by calculating resting energy expenditure
(REE):
• • By simple calculation: REE in kcal/ day = 25 × weight in kg.
• • Harris Benedict equation: REE in men = 66 + (13.7×weight in kg) + (5 ×
ht in cm) – (6.7 × age in years). In women = 655 + (9.6 × weight) + (1.8 × ht)
– (4.7 × age). Activity/disease/thermal factors are also added.
• • Indirect calorimetry: It is more accurate method done using special
instrument. REE: = (3.9 × VO2) + (1.1 × VCO2) – 61.
10. BURNS
• Thing WE MUST KNOW= Marjolin Ulcer, how to give first aid, degree
of burns
CREST
11. Degrees of Burn******
1st Degree=epidermis(superficial thickness)
2nd Degree=epidermis and dermis (partial thickness)
3rd Degree=Full thickness
4th degree: Involves the underlying tissues—muscles, bones.
12.
13. • Depending on thickness of skin involved
a. Partial thickness burns: It is either first or second degree burn which is red and painful, often with blisters.
b. Full thickness burns: It is third degree burns which is charred, insensitive, deep involving all layers of the skin
Depending on the Percentage of Burns Mild (Minor):
1. Partial thickness burns < 15% in adult or <10% in children
2. Full thickness burns less than 2%.
3. Can be treated on outpatient basis.
Moderate:
1. Second degree of 15-25% burns (10-20% in children).
2. Third degree between 2-10% burns.
3. Burns which are not involving eyes, ears, face, hand, feet, perineum.
Major (severe):
1. Second degree burns more than 25% in adults, in children more than 20%.
2. All third degree burns of 10% or more.
3. Burns involving eyes, ears, feet, hands, perineum.
4. All inhalation and electrical burns.
5. Burns with fractures or major mechanical trauma.
15. Effect of Burn Injury
1. Systemic infection like pneumonia, bacteraemia, septicaemia can occur.
2. Burns itself creates immunosuppression.
3. Sepsis is identified by fever, lethargy, leukocytosis, thrombocytopenia.
4. Infections
5. Shock due to hypovolaemia.
6. Renal failure.
7. Pulmonary oedema, respiratory infection, adult respiratory distress
syndrome (ARDS), respiratory failure.
8. Curling’s ulcer (seen in burns > 35%).
16.
17. MANAGEMENT OF BURNS
• First Aid ****
• Stop the burning process and keep the patient away from the burning
area.
• Cool the area with tap water by continuous irrigation for 20 minutes
(not cold water as it can cause hypothermia
18. Definitive Treatment
• Admit the patient.
• Maintain airway, breathing, circulation.
• Assess the percentage, degree, and type of burn.
• Keep the patient in a clean environment.
• Sedation and proper analgesia.
• Patient should be in burns unit (ideally air-conditioned) with barrier
nursing, sterile clothes, bed sheets with all aseptic methods.
19. Fluid Resuscitation
Fluids used are normal saline, ringer lactate, Hartmann fluid,
plasma. Ringer lactate is the fluid of choice. Blood is
transfused in later period (after 48 hours).
20. CONTRACTURE IN BURN WOUND
• Burn scar contracture is the tightening of the skin after a second or third degree burn. When skin is burned, the surrounding skin
begins to pull together, resulting in a contracture. It needs to be treated as soon as possible because the scar can result in
restriction of movement around the injured area. Contracture in burns can occur anywhere. It is more common wherein
flexibility and mobility is present like along the joint, eyelids, cheeks, lips, neck, elbow, knee
Complications:
***Marjolin’s ulcer:
1. It is a very well-differentiated squamous cell carcinoma occurring in a scar ulcer due to repeated breakdown (unstable scar
of long duration).
2. It is locally malignant.
3. As there are no lymphatics in the scar, so there is no spread to lymph nodes.
4. As there are no nerves in the scar it is painless.
5. It has raised and everted edge with induration.
6. Biopsy confirms the diagnosis.
7. Treatment: Radiotherapy is not given for Marjolin’s ulcer. Treatment is either wide excision or amputation. It is curable. Once it
spreads out of the scar tissue it behaves like any other squamous cell carcinoma and so can spread to regional lymph nodes.