t-RNA Type of RNA molecule that helps to decode a messenger RNA

2. Topic – t-RNA

3. •Transfer ribonucleic acid (t-RAN) is a type of
RNA molecule that helps decode a messenger
RNA (mRNA). Sequence into a protein. t-RNA
function at specific sites in the ribosome during
translation, which is a process that synthesize a
protein from an m-RNA molecule.

4. The job of t-RNA is to read the message of nucleic
acids, or nucleotides, and translate it into proteins,
or amino acid. The process of making a protein
from an m-RNA template is called translation

5. The molecule has a distinctive folded structure with
three hairpin loops that form the shape of a three
leafed clover. One of these hairpin loops contain a
sequence called the anticodon, which can recognize
and decode an m-RNA codon. Each t-RNA has its
corresponding amino acid attached to its end.

7. The acceptor stem may contain non-Watson-Crick
base pairs. The CCA tail is a cytosine-cytosine-adenine
sequence at the 3’ end of the t-RNA molecule. The
amino acid located onto the t-RNA by aminoacyl t-
RNA synthetases, to form aminoacyl – t-RNA , is
covalently bonded to the 3’- hydroxyl group on the
CCA tail.

8. Cytoplasmic t-RNA are found in the fluid inside cell .
These t-RNAs help produce proteins from genes located
in the DNA in the DNA in the nucleus of the cell
.Although most DNA is nuclear, cellular structures called
mitochondria have a small amound of their own DNA,
called mitochondrial DNA.

9. In eukaryotes t-RNA is manufactured in the
nucleus from the DNA template by RNA
polymerase III, modified there then exported from
the nucleus to the cytoplasm for use in making
new proteins

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