This document discusses the biomedical effects of underwear. It covers three key areas:
1) The insulation of underwear is less important than other clothing since it is closest to the skin, but its tactile properties and moisture handling are more significant.
2) Tactility refers to the sense of touch, which underwear impacts through properties like smoothness, softness, and moisture uptake.
3) The ideal underwear would wick sweat away rapidly, absorb large amounts without feeling wet, and dry quickly while being lightweight and comfortable.