This is a genetic question: 6. John and Mary each have sisters with cystic fibrosis. They would like to marry and have children, but are concerned that they too may have a child with cystic fibrosis. Cystic fibrosis is an autosomal recessive disease located on chromosome 7. If John and Mary are each heterozygous for cystic fibrosis what is the probability of: A. Having 2 normal children and 2 affected children in any order? B. Having 3 normal children and 2 affected children in any order?.