This document presents research on the feasibility of using radioisotope-based electron sources for space applications. It introduces two new types of space propulsion systems: the Minaka thruster and Kabila thruster. The Minaka thruster uses clusters of self-powered radioisotope cells to generate micro-newtons of thrust. It applies the principle of self-sufficiency to power the radioisotope electron sources. The Kabila thruster uses a hollow cathode with a radioisotope heat source instead of a conventional heater. It was found to save up to 3% in overall power compared to conventional ion thrusters. Both systems aim to overcome the energetic limitations of traditional space propulsion through novel use of radioisotopes