Sian Oram, of the London School of Hygiene and Tropical Medicine, discusses the difficulties faced by people trafficked for labour exploitation - a group traditionally regarded as less needy than than people trafficked for sexual exploitation.
At our March claims club we covered a number of topics including:
- the Enterprise and Regulatory Reform Act (ERRA) 2013
- how to deal with stress in the workplace both in terms of civil claims and claims in the employment tribunal
- advice on dealing with HM Coroner.
View further resources and training on our website - https://www.brownejacobson.com/insurance
Isaac's Health Care Archimedes talk at Apollo CollegeIsaac Holeman
These are slides for a talk I gave at Apollo College of Nursing on 11.4.08 - Election Day. The topic of the two hour presentation was Health Care reform, the Archimedes movement, and leadership in health care. The slides are heavily modified from a basic version that many speakers from the Archimedes Movement use. This was my second talk at Apollo college. Thank you so much Jessica for inviting me, and to all you nursing students for listening so intently.
cheers
Isaac
Financial assistance and community health needs benefitsEY
With reporting requirements for hospitals on Form 990 Schedule H evolving, we examine interactions with the Internal Revenue Service and congressional activity related to such topics.
A Chicago case example of public health professionals allying with community ...Jim Bloyd, DrPH, MPH
Inspired by the Guide to Public Health Actions for Immigrant Rights, a coalition of health workers and community allies in Chicago have been organizing to pressure the Cook County Health and Hospitals System (CCHHS) to meet six demands to Protect Immigrant Health Now! Two promotoras de salud-Community Health Workers-from Enlace Chicago provided testimony at the September 1, 2017 meeting of the CCHHS Board,
marking a milestone in this campaign. Four additional leaders of the Public Health Woke coalition will join the two promotoras on the panel. They will describe the coalition’s collection of new data, use of the Thunderclap social media tool, relationship-building, analysis of local power structures, and the ethical duties of public health professionals in the context of mass deportation. The Co-Founder and Executive Director of Arab- American Family Services will describe her experience as an ally, and the importance of centering immigrant voices in the fight for sanctuary health care for immigrants and all marginalized people; The role of Cook County Commissioner Jesús ‘Chuy’ García’s 7th District Health Task Force will be
described; A Past-President of APHA (faculty at UIC School of Public Health and National Collaborative for Health Equity Board Member) will discuss the historical commitment of Cook County, Illinois, to provide health care to all people; and a leader with the Collaborative for Health Equity Cook County will moderate and guide one participatory activity. This session will emphasize audience participation & dialogue.
More info go to CHECookCounty.org Follow @CHECookCounty
At our March claims club we covered a number of topics including:
- the Enterprise and Regulatory Reform Act (ERRA) 2013
- how to deal with stress in the workplace both in terms of civil claims and claims in the employment tribunal
- advice on dealing with HM Coroner.
View further resources and training on our website - https://www.brownejacobson.com/insurance
Isaac's Health Care Archimedes talk at Apollo CollegeIsaac Holeman
These are slides for a talk I gave at Apollo College of Nursing on 11.4.08 - Election Day. The topic of the two hour presentation was Health Care reform, the Archimedes movement, and leadership in health care. The slides are heavily modified from a basic version that many speakers from the Archimedes Movement use. This was my second talk at Apollo college. Thank you so much Jessica for inviting me, and to all you nursing students for listening so intently.
cheers
Isaac
Financial assistance and community health needs benefitsEY
With reporting requirements for hospitals on Form 990 Schedule H evolving, we examine interactions with the Internal Revenue Service and congressional activity related to such topics.
A Chicago case example of public health professionals allying with community ...Jim Bloyd, DrPH, MPH
Inspired by the Guide to Public Health Actions for Immigrant Rights, a coalition of health workers and community allies in Chicago have been organizing to pressure the Cook County Health and Hospitals System (CCHHS) to meet six demands to Protect Immigrant Health Now! Two promotoras de salud-Community Health Workers-from Enlace Chicago provided testimony at the September 1, 2017 meeting of the CCHHS Board,
marking a milestone in this campaign. Four additional leaders of the Public Health Woke coalition will join the two promotoras on the panel. They will describe the coalition’s collection of new data, use of the Thunderclap social media tool, relationship-building, analysis of local power structures, and the ethical duties of public health professionals in the context of mass deportation. The Co-Founder and Executive Director of Arab- American Family Services will describe her experience as an ally, and the importance of centering immigrant voices in the fight for sanctuary health care for immigrants and all marginalized people; The role of Cook County Commissioner Jesús ‘Chuy’ García’s 7th District Health Task Force will be
described; A Past-President of APHA (faculty at UIC School of Public Health and National Collaborative for Health Equity Board Member) will discuss the historical commitment of Cook County, Illinois, to provide health care to all people; and a leader with the Collaborative for Health Equity Cook County will moderate and guide one participatory activity. This session will emphasize audience participation & dialogue.
More info go to CHECookCounty.org Follow @CHECookCounty
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Patricia Latter REF "Routes to Impact" presentation 26/05/2016LIDC
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Malcolm Potts Crisis in the Sahel: Where Population and Climate Change Are Co...LIDC
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His work has revealed the threats posed to health and well being by environmental change, but has emphasized and identified the positive opportunities, and the co-benefits they can generate.
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
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and severe subclassifications (American Psychiatric Association, 2013).
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comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae