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Human Digestion
Nutrition
Process by which organisms obtain and utilize their food.
There are two parts to Nutrition:
1. Ingestion- process of taking food into the
digestive system so that it may be
hydrolized or digested.
2. Digestion- the breakdown of food (either
chemically or mechanically) in order to
utilize nutrients
Types of Nutrients
• Micronutrients- vitamins, minerals, & water

• Macronutrients- proteins, lipids,
carbohydrates, etc…
Human digestive
system
Ingestion

• Mouth

– mechanical digestion
• teeth
– breaking up food

– chemical digestion
• saliva
– amylase
» enzyme digests starch
– mucin
» slippery protein (mucus)
» protects soft lining of digestive system
» lubricates food for easier swallowing
– buffers
» neutralizes acid to prevent tooth decay
– anti-bacterial chemicals
» kill bacteria that enter mouth with food
mouth
break up food
digest starch
kill germs
moisten food
Mouth
• Chemical and
mechanical
digestion.
• Food is chewed
(masticated)
mechanically.
• A bolus (lump) is
formed with saliva
and the tongue.
Swallowing (& not choking)

• Epiglottis
– flap of cartilage
– closes trachea (windpipe) when swallowing
– food travels down esophagus

• Peristalsis
– involuntary muscle contractions to move food along
Which type of digestion is the
following?
1. Chewing a saltine? 2. Saliva breaking the saltine down into molecules of
glucose? 3. Your tongue breaking pieces of a hamburger apart?

4. Pepsin (an enzyme) in your stomach breaking the
hamburger into amino acids?
Pharynx
• The back of the
throat.
• Larynxpassage for air,
closes when we
swallow.
• Is approximately
15cm long.
Digestive Glands
• Groups of
specialized
secretory
cells.
• Found in the
lining of the
alimentary
canal or
accessory
organs.
Peristalsis
• series of involuntary
wave-like muscle
contractions which
move food along the
digestive tract
Stomach
• Food is temporarily
stored here.
• Gastric juices are
secreted.
• Has layers of
muscle that line the
inside.
• Mechanically and
chemically breaks
down food.
Stomach
• Functions
– food storage
• can stretch to fit ~2L food

– disinfect food
• HCl = pH 2
– kills bacteria

– chemical digestion
• pepsin
– enzyme breaks down proteins

But the stomach is made out of protein!
What stops the stomach from digesting itself?
mucus secreted by stomach cells protects
stomach lining
mouth
break up food
digest starch
kill germs
moisten food

stomach
kills germs
break up food
digest proteins
store food

sphincter

sphincter
Gastric Juices

• Secreted by the
stomach.
• Acidic (pH 1.5-2.5)
(HCl).
• Pepsin- an enzyme that
breaks down large
proteins into amino
acids.
• Food is further broken
down into a thin liquid
called chyme.
Accessory Organs
• Pancreas
• Gall Bladder
• Spleen
Gall bladder
• Pouch structure located near the liver
which concentrates and stores bile
• Bile duct – a long tube that carries BILE.
The top half of the common bile duct is
associated with the liver, while the bottom
half of the common bile duct is associated
with the pancreas, through which it passes
on its way to the intestine.
BILE
• Bile emulsifies lipids (physically breaks
apart FATS)
• Bile is a bitter, greenish-yellow alkaline
fluid, stored in the gallbladder between
meals and upon eating is discharged into
the duodenum where it aids the process of
digestion.
Pancreas
• An organ which secretes both digestive
enzymes (exocrine) and hormones (endocrine)
• ** Pancreatic juice digests all major nutrient
types.
• Nearly all digestion occurs in the small intestine
& all digestion is completed in the SI.
Pancreas

• Digestive enzymes
– digest proteins

• trypsin, chymotrypsin

– digest starch
• amylase

• Buffers
– neutralizes
acid from
stomach
Liver
• Function
– produces bile
• bile stored in gallbladder until needed
• breaks up fats
– act like detergents to breakup fats

bile contains
colors from old
red blood cells
collected in liver =
iron in RBC rusts &
makes feces brown
mouth
break up food
digest starch
kill germs
moisten food
liver
produces bile
- stored in gall bladder
break up fats
pancreas
produces enzymes to
digest proteins & starch

stomach
kills germs
break up food
digest proteins
store food
Small Intestine
• Most chemical
digestion takes place
here.
• Simple sugars and
proteins are absorbed
into the inner lining.
• Fatty acids and
glycerol go to lymphatic
system.
• Lined with villi, which
increase surface area for
absorption, one cell
thick.
Small intestine

• Function

– chemical digestion
• major organ of digestion & absorption

– absorption through lining
• over 6 meters!
• small intestine has huge surface area = 300m 2
(~size of tennis court)

• Structure
– 3 sections
• duodenum = most digestion
• jejunum = absorption of nutrients & water
• ileum = absorption of nutrients & water
mouth
break up food
digest starch
kill germs
moisten food

pancreas
produces enzymes to
digest proteins & starch

stomach
kills germs
break up food
digest proteins
store food
Absorption in the SI
•

Much absorption is thought to occur directly through the wall
without the need for special adaptations

•

Almost 90% of our daily fluid intake is absorbed in the small
intestine.

•

Villi - increase the surface area of the small intestines, thus
providing better absorption of materials
Absorption by Small Intestines
• Absorption through villi & microvilli
– finger-like projections
– increase surface area for absorption
VILLI
Large intestines
(colon)
• Function
– re-absorb water
• use ~9 liters of water every
day in digestive juices
• > 90% of water reabsorbed
– not enough water absorbed
» diarrhea
– too much water absorbed
» constipation
Large Intestine
• Solid materials pass
through the large
intestine.
• These are undigestible
solids (fibers).
• Water is absorbed.
• Vitamins K and B are
reabsorbed with the
water.
• Rectum- solid wastes
exit the body.
Appendix

Vestigial organ
Rectum
• Last section of colon
(large intestines)
– eliminate feces
• undigested materials
– extracellular waste
» mainly cellulose
from plants
» roughage or fiber
– masses of bacteria

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The digestivesystem

  • 2. Nutrition Process by which organisms obtain and utilize their food. There are two parts to Nutrition: 1. Ingestion- process of taking food into the digestive system so that it may be hydrolized or digested. 2. Digestion- the breakdown of food (either chemically or mechanically) in order to utilize nutrients
  • 3. Types of Nutrients • Micronutrients- vitamins, minerals, & water • Macronutrients- proteins, lipids, carbohydrates, etc…
  • 5. Ingestion • Mouth – mechanical digestion • teeth – breaking up food – chemical digestion • saliva – amylase » enzyme digests starch – mucin » slippery protein (mucus) » protects soft lining of digestive system » lubricates food for easier swallowing – buffers » neutralizes acid to prevent tooth decay – anti-bacterial chemicals » kill bacteria that enter mouth with food
  • 6. mouth break up food digest starch kill germs moisten food
  • 7. Mouth • Chemical and mechanical digestion. • Food is chewed (masticated) mechanically. • A bolus (lump) is formed with saliva and the tongue.
  • 8. Swallowing (& not choking) • Epiglottis – flap of cartilage – closes trachea (windpipe) when swallowing – food travels down esophagus • Peristalsis – involuntary muscle contractions to move food along
  • 9. Which type of digestion is the following? 1. Chewing a saltine? 2. Saliva breaking the saltine down into molecules of glucose? 3. Your tongue breaking pieces of a hamburger apart? 4. Pepsin (an enzyme) in your stomach breaking the hamburger into amino acids?
  • 10. Pharynx • The back of the throat. • Larynxpassage for air, closes when we swallow. • Is approximately 15cm long.
  • 11. Digestive Glands • Groups of specialized secretory cells. • Found in the lining of the alimentary canal or accessory organs.
  • 12. Peristalsis • series of involuntary wave-like muscle contractions which move food along the digestive tract
  • 13. Stomach • Food is temporarily stored here. • Gastric juices are secreted. • Has layers of muscle that line the inside. • Mechanically and chemically breaks down food.
  • 14. Stomach • Functions – food storage • can stretch to fit ~2L food – disinfect food • HCl = pH 2 – kills bacteria – chemical digestion • pepsin – enzyme breaks down proteins But the stomach is made out of protein! What stops the stomach from digesting itself? mucus secreted by stomach cells protects stomach lining
  • 15. mouth break up food digest starch kill germs moisten food stomach kills germs break up food digest proteins store food sphincter sphincter
  • 16. Gastric Juices • Secreted by the stomach. • Acidic (pH 1.5-2.5) (HCl). • Pepsin- an enzyme that breaks down large proteins into amino acids. • Food is further broken down into a thin liquid called chyme.
  • 17. Accessory Organs • Pancreas • Gall Bladder • Spleen
  • 18. Gall bladder • Pouch structure located near the liver which concentrates and stores bile • Bile duct – a long tube that carries BILE. The top half of the common bile duct is associated with the liver, while the bottom half of the common bile duct is associated with the pancreas, through which it passes on its way to the intestine.
  • 19. BILE • Bile emulsifies lipids (physically breaks apart FATS) • Bile is a bitter, greenish-yellow alkaline fluid, stored in the gallbladder between meals and upon eating is discharged into the duodenum where it aids the process of digestion.
  • 20. Pancreas • An organ which secretes both digestive enzymes (exocrine) and hormones (endocrine) • ** Pancreatic juice digests all major nutrient types. • Nearly all digestion occurs in the small intestine & all digestion is completed in the SI.
  • 21. Pancreas • Digestive enzymes – digest proteins • trypsin, chymotrypsin – digest starch • amylase • Buffers – neutralizes acid from stomach
  • 22.
  • 23. Liver • Function – produces bile • bile stored in gallbladder until needed • breaks up fats – act like detergents to breakup fats bile contains colors from old red blood cells collected in liver = iron in RBC rusts & makes feces brown
  • 24. mouth break up food digest starch kill germs moisten food liver produces bile - stored in gall bladder break up fats pancreas produces enzymes to digest proteins & starch stomach kills germs break up food digest proteins store food
  • 25. Small Intestine • Most chemical digestion takes place here. • Simple sugars and proteins are absorbed into the inner lining. • Fatty acids and glycerol go to lymphatic system. • Lined with villi, which increase surface area for absorption, one cell thick.
  • 26. Small intestine • Function – chemical digestion • major organ of digestion & absorption – absorption through lining • over 6 meters! • small intestine has huge surface area = 300m 2 (~size of tennis court) • Structure – 3 sections • duodenum = most digestion • jejunum = absorption of nutrients & water • ileum = absorption of nutrients & water
  • 27. mouth break up food digest starch kill germs moisten food pancreas produces enzymes to digest proteins & starch stomach kills germs break up food digest proteins store food
  • 28. Absorption in the SI • Much absorption is thought to occur directly through the wall without the need for special adaptations • Almost 90% of our daily fluid intake is absorbed in the small intestine. • Villi - increase the surface area of the small intestines, thus providing better absorption of materials
  • 29. Absorption by Small Intestines • Absorption through villi & microvilli – finger-like projections – increase surface area for absorption
  • 30. VILLI
  • 31. Large intestines (colon) • Function – re-absorb water • use ~9 liters of water every day in digestive juices • > 90% of water reabsorbed – not enough water absorbed » diarrhea – too much water absorbed » constipation
  • 32. Large Intestine • Solid materials pass through the large intestine. • These are undigestible solids (fibers). • Water is absorbed. • Vitamins K and B are reabsorbed with the water. • Rectum- solid wastes exit the body.
  • 34. Rectum • Last section of colon (large intestines) – eliminate feces • undigested materials – extracellular waste » mainly cellulose from plants » roughage or fiber – masses of bacteria

Editor's Notes

  1. After chewing and swallowing, it takes 5 to 10 seconds for food to pass down the esophagus to the stomach, where it spends 2 to 6 hours being partially digested. Final digestion and nutrient absorption occur in the small intestine over a period of 5 to 6 hours. In 12 to 24 hours, any undigested material passes through the large intestine, and feces are expelled through the anus.
  2. Still, the epithelium is continually eroded, and the epithelium is completely replaced by mitosis every three days. Gastric ulcers, lesions in the stomach lining, are caused by the acid-tolerant bacterium Heliobacter pylori. Ulcers are often treated with antibiotics. Pepsin is secreted in an inactive form, called pepsinogen by specialized chief cells in gastric pits. Parietal cells, also in the pits, secrete hydrochloric acid which converts pepsinogen to the active pepsin only when both reach the lumen of the stomach, minimizing self-digestion. Also, in a positive-feedback system, activated pepsin can activate more pepsinogen molecules.
  3. About every 20 seconds, the stomach contents are mixed by the churning action of smooth muscles. As a result of mixing and enzyme action, what begins in the stomach as a recently swallowed meal becomes a nutrient-rich broth known as acid chyme. At the opening from the stomach to the small intestine is the pyloric sphincter, which helps regulate the passage of chyme into the intestine. A squirt at a time, it takes about 2 to 6 hours after a meal for the stomach to empty.