1. The Different Pattern Of Inheritance
betweenmitochondrialandnucleargene
By
NABA’A AL WAZEN
2.
3. Mitochondrial DNA
• mitochondrial-DNA It is found in the mitochondria of a cell.
Mitochondrial DNA has only one chromosome which is
comparatively shorter and they do not code for all the
proteins but only specific proteins.
• This DNA make its own tRNA and even rRNA. It replicates
separately from the nuclear DNA and is passed on to the
progeny from mother only.
• That being the reason for which it does not undergo
recombination. It is even read with a different genetic code
from the nuclear DNA itself.
4. Main Difference
• The main difference between nuclear DNA and mitochondrial
DNA is,nuclear DNA is the standard 46 chromosome
containing DNA in which you inherit 23 chromosome from one
parent and the rest 23 from another one.
• On the other hand, mitochondrial DNA contains just one
chromosome, like a circular genome. This chromosome is
much shorter and codes for proteins that are used in
metabolic purposes.
• Another main difference is that mitochondrial DNA is only
transmitted from mother and never from the father while
nuclear DNA is inherited from both, mother and father.
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7.
8. Mitochondrial Eve
• In human genetics, the Mitochondrial Eve (also mt-Eve, mt-
MRCA)
• is the matrilineal most recent common ancestor (MRCA) of all
currently living humans,
• i.e., the most recent woman from whom all living humans
descend in an unbroken line purely through their mothers,
and through the mothers of those mothers, back until all lines
converge on one woman.