1) A survey was conducted of 826 Macau teenagers (380 males, 446 females) to understand their sexual knowledge and experiences. 2) The results showed that 9.87% of males and 4.48% of females reported having sexual experiences. Most partners were high school or university students of similar ages. 3) For both male and female teenagers, the highest percentage were in their first year of high school, followed by second and third years. Fewer were in primary school or had not attended school.