HARNESSING PHARMA WORKFLOW WITH ELNsELECTRONIC LABORATORY NOTEBOOKSWANDA HARTMANN OEHRLI
Contents20% growth rate per year one of the fastestgrowing technologies
ELNA daily record-keeping of the pharma process that includes at least the content of a paper notebook
Helps to manage data from discovery to commercializationPharma Workflow Example
Importance of Notebooks
Necessity of ELNsACCELERATION OF DRUG DISCOVERY!
Current ELN Usershttp://www.genengnews.com/articles/chitem.aspx?aid=2481
Barriers to Implementation
Resistance levels are low
ELN ArchitectureDatabaseApplication/Web server  Software mainly handles work processflowPDA                        laptop                      ComputerCopies of files will reside locally, short and long term on webservers and DB
Most Popular Vendor
Predictions
Recommendations:
Referenceshttp://www.informationliberation.com/files/anthraxVaccine.jpghttp://www.healthsystem.virginia.edu/internet/uvamellon/images/DrugDiscovery.jpghttp://www.clinical-trials-info.com/wp-content/uploads/2009/02/drug-discovery-11.jpghttp://www.labtronics.com/Images/eln-small.jpghttp://en.wikipedia.org/wiki/Electronic_lab_notebookhttp://acdlabs.typepad.com/my_weblog/2007/07/electronic-lab-.htmlhttp://www.krackeler.com/graphics/0007/jpg/63001000a1.jpghttp://www.labtrack.com/files/q1_blank_screen.jpghttp://www.genengnews.com/articles/chitem.aspx?aid=1075www.indiana.edu/~cheminfo/C571/ELNlecture20030825.ppt http://www.scientific-computing.com/products/product_details.php?product_id=302http://knol.google.com/k/shawn-mcclelland/electronic-lab-notebooks/3mhmqlqy4k0no/1#http://www.scientificcomputing.com/Electronic-Laboratory-Notebooks-Enter-Mainstream-Informatics.aspxElliott, Michael H; Electronic Laboratory Notebooks: A Foundation for Scientific Knowledge Management Edition III; Atrium Research & Consulting LLC; Wilton, CT USA http://www.measurementdevices.com/index.php?name=News&file=article&sid=1597http://www.chem.agilent.com/en-US/Products/software/kalabieeln/Pages/default.aspxhttp://www.streetinsider.com/Earnings/Symyx+Announces+Electronic+Laboratory+Notebook+and+LIMS+Partnership+With+Thermo+Fisher+Scientific/4491417.htmlSome images are from Microsoft Clip Arthttp://www.medicalnewstoday.com/articles/29934.php (resistance to ELN)http://www.pr.com/press-release/44174 (LabTrak)http://www.ddw-online.com/industrynews/124013/new_enterprise_electronic_lab_notebook.html (Symex notebook)Networking will slow things down; cost http://pipeline.corante.com/archives/2008/02/07/write_it_down_write_it_down.phphttp://www.genengnews.com/articles/chitem.aspx?aid=2481http://www.phschool.com/science/science_news/articles/images/electron_runs_through_01.jpghttp://www.sxst.it/siti/sxst/sxst.nsf/seminari/cambridgesoft/ELN-Intro.pdfPharma company logs came from company websites.Google Keyword searchesreview of ELN electronic laboratory notebook

HARNESSING PHARMA WORKFLOW WITH ELNs

Editor's Notes

  • #8 Merck implemented in 2000 Glaxo – 3500 R&D usersEli Lilly states productivity increase, ROI 5%
  • #9 Rose liked this one
  • #11 Thick/thin client; thick client needs application install Internet Exporer is thin Thick need an application to run; Skype