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LAB NOTEBOOKS AS
DATA MANAGEMENT
Supporting Good Practices and the Transition
from Paper to Electronic Notebooks


                            Dr. Kristin A. Briney
                            The University of Wisconsin-Madison

                            SLA Winter Virtual Conference
                            7 December 2012
Pre-publication v. Post-publication Data
• Lot of management work done in second area
• This talk focuses on first area
  • Scientists need most help here
• Data management very important in pre-publication
  • Help scientists find their own data, saving time and effort
  • Help scientist share data
    • Even within a lab this is important!
  • Help senior researchers/PIs keep track of data-long term as
    subordinates leave
  • Makes post-publication management smoother
The Scientific Process
• Literature review
• Experiment design and grant writing
• Acquire raw data
• Data analysis
• Repeat acquisition and analysis
• (Maybe share data)
• Make data presentational and write paper
• Submit paper and eventually publish it
• [Post-publication]



                                   *Domain of the lab notebook
Data and Metadata Currently




Flickr: proteinbiochemist   Flickr: jurvetson
Current Data and Metadata Problems
• Searching is a huge problem
  • Effectively need to search 2 difference systems to find one
    experiment
• Long-term concerns with keeping data and metadata
  together
• Back-ups are an issue
• No standard for digital file organization


• Practices vary lab-to-lab AND researcher-to-researcher
  • Extremely difficult to find someone else’s data currently
Data and Metadata in the Future
    • Electronic Lab Notebooks (ELNs)




Note: I am not endorsing any particular lab notebook software package.
      I will cover software that UW-Madison has looked into.
Data and Metadata in the Future
• Easy searching
• All files in one place
• Linking between pages
• Customization
• Easier sharing
  • Controlled access
• Audit trail
  • eSignatures
  • Revision history
Data and Metadata in the Future
• Bugs, upgrades, and other digital issues
• Effort to transition
• Unsettled ELN market
  • In first generation of ELNs
• Using files in 10 years
• Data storage
  • Location and ownership issues
• Data security and backups
  • Need to have reliable system in place
Recent UW-Madison ELN Pilot
• Tested 2 notebooks, CERF and eCAT
   • 55 users, majority never used an ELN before
• At end of pilot, 91% of respondents wanted to continue
 using an ELN
  • 60% of CERF users wanted to try a different ELN
• Required <12 hours to learn interface
  • Users employed training sessions and trial and error to learn
• Users liked linking and adding data files
• Drawing tools and mobile versions did not live up to
 expectations

• http://academictech.doit.wisc.edu/ideas/electronic-lab-notebooks
How Librarians Can Help
• Teach basic information organization
• Help preserve old notebooks
• Know the properties of a good ELN
• Educate on how to choose an ELN
• Support the transition to ELNs
Teach Basic Information Organization
      • Surrogate records!
        • Record necessary metadata in notebook to point to file
        • How to organize digital files
        • This is our wheelhouse and will help scientists with searching
      • Suggest file naming and organization conventions
        • Avoid “ /  : * ? ‘ < > [ ] & $ characters
        • Use underscores not spaces
        • Date files and do it consistently (YYYY-MM-DD)
        • Label folders with reference to notebook
             • Example: C:DocumentsBrineyNotebookIV2012-12-07




http://researchdata.wisc.edu/manage-your-data/file-naming-and-versioning/
Preserve Old Paper Notebooks
                     • Add lab notebooks to
                      library collection
                       • Ask what do retiring
                        scientists do with their
                        notebooks?


                     • Did you know?
                       • Data for patents needs
Flickr: mabelsound
                         to be retained >26 yr
Know the Properties of a Good ELN
• Note taking and searching ability
• Adding external files
• Adding links between pages
• Ability to export
• Access permissions
• eSignatures
• Log of revision history
   • Some researchers are using general note taking software, which
     doesn’t have this feature. I don’t recommend this software for a lab
     notebook because of this.
Educate on Choosing an ELN
• Needs assessment
• Test the software
• Have an adoption plan
• Have an exit strategy




• Note: I do not recommend free/demo version of software
  • Hosting may be outside US
  • No sharing
Needs Assessment
• How much do I want to integrate the ELN into my
  workflow?
• How much customization do I want?
• Do I need to share?
  • PI should have access to all notebooks at very least
• Where should the information be stored?
  • If cloud-based, look for US-based hosting
• Can I support a local server hosting the ELN?
• How much can I spend?
  • Open Source up to $1000 per person per year
Test the Software
• Can be big financial investment
• One ELN software package will not work for everyone


• Ask to test before purchase
  • Ideally a week-to-month long test in the lab
  • Use as a notebook and look at features in depth
  • Keep both paper and electronic records during test



• Takes time and effort to test but very important
   • Won’t buy a car without a test drive. Same for an ELN.
Have an Adoption Plan
• Large shift in workflow in adoption of ELN
• Adoption strategies
  • Adopt at beginning of a project
  • Rolling adoption with new researchers
  • Or just plunge in!



• Put someone in charge of installation
• Get software support
• Get IT support
  • Backups
Have an Exit Strategy
• No guarantee that current notebooks will be here in 5
 years

• Ideally, write files to an open file format
   • PDF common
   • XML
   • HTML
   • Word (.doc/.docx)
• At worst, need to be able to print out all pages
  • Useful to have a batch method to do this
Support the Transition to ELNs
• Transitioning to an ELN involves scientists, library and IT
   • Who is going to train scientists?
• Library can offer important training on ELN software
   • Fold into information literacy instruction
   • Great opportunity to also teach basic data management skills
   • Target grad students (academia) and focus on research groups
• Keep an eye on the changing market
  • Products coalescing market share
  • Developing standards
The Future is ELNs
• ELNs will help with data management in the laboratory
• ELNs will become the norm in research by the end of my
 career
  • Researchers in industry may be using ELNs now
• May be 5-10 years before market coalesces
  • Enterprise ahead of academic market
  • Good products available now
• Lots of benefits and some risks in adopting an ELN
   • Keeping a paper notebook has risks but they’re different
   • Need digital infrastructure to support ELN
   • If risks too big, wait a few years
Summary
• Scientists need help with pre-publication data
  management
• Paper lab notebooks are problematic in a digital world
• ELNs can solve these issues but have concerns of their
  own
• Librarians can help by
  • Teaching good digital organization skills
  • Preserving old paper notebooks
  • Consult with scientist on good ELNs and transitioning to them
• ELNs are the future and scientists will need support with
 the transition
Resources
• (2009). Guide for keeping laboratory records. Rockville,
  MD: National Cancer Institute, Technology Transfer
  Center.
• Kanare, H. M. (1985). Writing the laboratory
  notebook. Washington, D.C.: American Chemical Society.
• DoIT Academic Technologies (2012). Electronic Lab
  Notebook Pilot at the University of Wisconsin-Madison.
  Madison, WI: University of Wisconsin-Madison
  http://academictech.doit.wisc.edu/ideas/electronic-lab-
  notebooks
Thanks!
• SLA DCHE and PHT
• Jan Cheetham, UW DoIT Academic Technologies
• Victoria Sutton, UW WARF




• This presentation available under a Creative Commons
 Attribution-NonCommercial 3.0 license



• Slides will be available at:
 http://www.slideshare.net/kbriney

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Lab Notebooks as Data Management (SLA Winter Virtual Conference 2012)

  • 1. LAB NOTEBOOKS AS DATA MANAGEMENT Supporting Good Practices and the Transition from Paper to Electronic Notebooks Dr. Kristin A. Briney The University of Wisconsin-Madison SLA Winter Virtual Conference 7 December 2012
  • 2. Pre-publication v. Post-publication Data • Lot of management work done in second area • This talk focuses on first area • Scientists need most help here • Data management very important in pre-publication • Help scientists find their own data, saving time and effort • Help scientist share data • Even within a lab this is important! • Help senior researchers/PIs keep track of data-long term as subordinates leave • Makes post-publication management smoother
  • 3. The Scientific Process • Literature review • Experiment design and grant writing • Acquire raw data • Data analysis • Repeat acquisition and analysis • (Maybe share data) • Make data presentational and write paper • Submit paper and eventually publish it • [Post-publication] *Domain of the lab notebook
  • 4. Data and Metadata Currently Flickr: proteinbiochemist Flickr: jurvetson
  • 5. Current Data and Metadata Problems • Searching is a huge problem • Effectively need to search 2 difference systems to find one experiment • Long-term concerns with keeping data and metadata together • Back-ups are an issue • No standard for digital file organization • Practices vary lab-to-lab AND researcher-to-researcher • Extremely difficult to find someone else’s data currently
  • 6. Data and Metadata in the Future • Electronic Lab Notebooks (ELNs) Note: I am not endorsing any particular lab notebook software package. I will cover software that UW-Madison has looked into.
  • 7. Data and Metadata in the Future • Easy searching • All files in one place • Linking between pages • Customization • Easier sharing • Controlled access • Audit trail • eSignatures • Revision history
  • 8. Data and Metadata in the Future • Bugs, upgrades, and other digital issues • Effort to transition • Unsettled ELN market • In first generation of ELNs • Using files in 10 years • Data storage • Location and ownership issues • Data security and backups • Need to have reliable system in place
  • 9. Recent UW-Madison ELN Pilot • Tested 2 notebooks, CERF and eCAT • 55 users, majority never used an ELN before • At end of pilot, 91% of respondents wanted to continue using an ELN • 60% of CERF users wanted to try a different ELN • Required <12 hours to learn interface • Users employed training sessions and trial and error to learn • Users liked linking and adding data files • Drawing tools and mobile versions did not live up to expectations • http://academictech.doit.wisc.edu/ideas/electronic-lab-notebooks
  • 10. How Librarians Can Help • Teach basic information organization • Help preserve old notebooks • Know the properties of a good ELN • Educate on how to choose an ELN • Support the transition to ELNs
  • 11. Teach Basic Information Organization • Surrogate records! • Record necessary metadata in notebook to point to file • How to organize digital files • This is our wheelhouse and will help scientists with searching • Suggest file naming and organization conventions • Avoid “ / : * ? ‘ < > [ ] & $ characters • Use underscores not spaces • Date files and do it consistently (YYYY-MM-DD) • Label folders with reference to notebook • Example: C:DocumentsBrineyNotebookIV2012-12-07 http://researchdata.wisc.edu/manage-your-data/file-naming-and-versioning/
  • 12. Preserve Old Paper Notebooks • Add lab notebooks to library collection • Ask what do retiring scientists do with their notebooks? • Did you know? • Data for patents needs Flickr: mabelsound to be retained >26 yr
  • 13. Know the Properties of a Good ELN • Note taking and searching ability • Adding external files • Adding links between pages • Ability to export • Access permissions • eSignatures • Log of revision history • Some researchers are using general note taking software, which doesn’t have this feature. I don’t recommend this software for a lab notebook because of this.
  • 14. Educate on Choosing an ELN • Needs assessment • Test the software • Have an adoption plan • Have an exit strategy • Note: I do not recommend free/demo version of software • Hosting may be outside US • No sharing
  • 15. Needs Assessment • How much do I want to integrate the ELN into my workflow? • How much customization do I want? • Do I need to share? • PI should have access to all notebooks at very least • Where should the information be stored? • If cloud-based, look for US-based hosting • Can I support a local server hosting the ELN? • How much can I spend? • Open Source up to $1000 per person per year
  • 16. Test the Software • Can be big financial investment • One ELN software package will not work for everyone • Ask to test before purchase • Ideally a week-to-month long test in the lab • Use as a notebook and look at features in depth • Keep both paper and electronic records during test • Takes time and effort to test but very important • Won’t buy a car without a test drive. Same for an ELN.
  • 17. Have an Adoption Plan • Large shift in workflow in adoption of ELN • Adoption strategies • Adopt at beginning of a project • Rolling adoption with new researchers • Or just plunge in! • Put someone in charge of installation • Get software support • Get IT support • Backups
  • 18. Have an Exit Strategy • No guarantee that current notebooks will be here in 5 years • Ideally, write files to an open file format • PDF common • XML • HTML • Word (.doc/.docx) • At worst, need to be able to print out all pages • Useful to have a batch method to do this
  • 19. Support the Transition to ELNs • Transitioning to an ELN involves scientists, library and IT • Who is going to train scientists? • Library can offer important training on ELN software • Fold into information literacy instruction • Great opportunity to also teach basic data management skills • Target grad students (academia) and focus on research groups • Keep an eye on the changing market • Products coalescing market share • Developing standards
  • 20. The Future is ELNs • ELNs will help with data management in the laboratory • ELNs will become the norm in research by the end of my career • Researchers in industry may be using ELNs now • May be 5-10 years before market coalesces • Enterprise ahead of academic market • Good products available now • Lots of benefits and some risks in adopting an ELN • Keeping a paper notebook has risks but they’re different • Need digital infrastructure to support ELN • If risks too big, wait a few years
  • 21. Summary • Scientists need help with pre-publication data management • Paper lab notebooks are problematic in a digital world • ELNs can solve these issues but have concerns of their own • Librarians can help by • Teaching good digital organization skills • Preserving old paper notebooks • Consult with scientist on good ELNs and transitioning to them • ELNs are the future and scientists will need support with the transition
  • 22. Resources • (2009). Guide for keeping laboratory records. Rockville, MD: National Cancer Institute, Technology Transfer Center. • Kanare, H. M. (1985). Writing the laboratory notebook. Washington, D.C.: American Chemical Society. • DoIT Academic Technologies (2012). Electronic Lab Notebook Pilot at the University of Wisconsin-Madison. Madison, WI: University of Wisconsin-Madison http://academictech.doit.wisc.edu/ideas/electronic-lab- notebooks
  • 23. Thanks! • SLA DCHE and PHT • Jan Cheetham, UW DoIT Academic Technologies • Victoria Sutton, UW WARF • This presentation available under a Creative Commons Attribution-NonCommercial 3.0 license • Slides will be available at: http://www.slideshare.net/kbriney