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Synagis
What is RSV? Respiratory syncytial virus or RSV causes most children to develop a cold. Most children will catch RSV by age 2.
What is RSV? In Babies born  prematurely or with certain lung and heart conditions, RSV  can lead to pneumonia, and bronchiolitis. RSV  is the #1 reason babies under 12months old in the US get hospitalized.
RSV Epidemiology In  most parts of the country, the RSV season runs from fall into spring, but can occur at different times each year.  The CDC will track the virology each year and physicians continue to check for changes  season to season.
RSV TRANSMISSION Transmitted by droplets, large particles, and fomites RSV survives up to 6 hours on stethoscopes, and  up to 12 hours on hard, nonporous surfaces. Over 50% of medical personnel infected when RSV is prevalent in the community Nosocomial infection remains to be a serious problem
Synagis: Mechanism of Action It is a monoclonal antibody that provides the specific antibodies that premature infants lack to help fight off RSV Disease Blocks fusion of infected host cells (synctial formation) Reduces viral infectivity and cell to cell transmission of the virus
Dosing
How Synagis is Supplied Synagis is supplied in single dose vials as a preservative free , solution at 100mg/ml in 0.5ml and 1.0 ml , containing either 50mg or 100mg respectively, for IM injection. It is ready to use, no longer requires any prep Upon receipt, Synagis should be stored 35.6 and 46.4 F in it original container Do not, freeze, or shake  vial or use beyond exp date.
SynagisAdministration Synagis should be administered in a dose of 15mg/Kg IM using 25 gauge 5/8 inch syringe in the anterolateral aspect of the thigh ,[object Object]
Injection volume over 1ml should be given as a  divided dose,[object Object]
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Synagis2010

  • 2. What is RSV? Respiratory syncytial virus or RSV causes most children to develop a cold. Most children will catch RSV by age 2.
  • 3. What is RSV? In Babies born prematurely or with certain lung and heart conditions, RSV can lead to pneumonia, and bronchiolitis. RSV is the #1 reason babies under 12months old in the US get hospitalized.
  • 4. RSV Epidemiology In most parts of the country, the RSV season runs from fall into spring, but can occur at different times each year. The CDC will track the virology each year and physicians continue to check for changes season to season.
  • 5. RSV TRANSMISSION Transmitted by droplets, large particles, and fomites RSV survives up to 6 hours on stethoscopes, and up to 12 hours on hard, nonporous surfaces. Over 50% of medical personnel infected when RSV is prevalent in the community Nosocomial infection remains to be a serious problem
  • 6. Synagis: Mechanism of Action It is a monoclonal antibody that provides the specific antibodies that premature infants lack to help fight off RSV Disease Blocks fusion of infected host cells (synctial formation) Reduces viral infectivity and cell to cell transmission of the virus
  • 8. How Synagis is Supplied Synagis is supplied in single dose vials as a preservative free , solution at 100mg/ml in 0.5ml and 1.0 ml , containing either 50mg or 100mg respectively, for IM injection. It is ready to use, no longer requires any prep Upon receipt, Synagis should be stored 35.6 and 46.4 F in it original container Do not, freeze, or shake vial or use beyond exp date.
  • 9.
  • 10.