This document provides an update on adult vaccinations and new recommendations from the Advisory Committee on Immunization Practices (ACIP). It evaluates the meningococcal vaccine Menveo® and finds it is effective against serogroups A, C, Y, and W-135. Menveo® was found to have a similar safety profile to other meningococcal vaccines. New recommendations include vaccinating adults ages 65 and older with pneumococcal and herpes zoster vaccines. The ACIP also recommends vaccinating pregnant women with Tdap and influenza vaccines.
This document discusses the experience with the PCV7 pneumococcal conjugate vaccination in children considered "at risk". It finds that:
1) PCV7 vaccination effectively reduces the risk of invasive pneumococcal disease (IPD) in children under 2 years old by 68-84.5%.
2) High risk groups recommended for vaccination include infants, toddlers up to 24 months, and children with conditions like sickle cell disease or HIV that increase risk of IPD.
3) The vaccination schedule involves a 2 or 3 dose primary series plus a booster, depending on age started, to provide high immunogenicity and efficacy against IPD above 80% in clinical trials.
Pequeño análisis sobre la necesidad de Vacunar y su impacto en la sociedad en...Dr. Manuel Concepción
Debo vacunar a mi hijo.doc
https://xemide-new-american-institute.tumblr.com/
https://www.youtube.com/watch?v=S1zaOUV0BTg
@newaericaninstitutexcupware
https://twitter.com/grow_follow
"Brian Shilhavy"
Dr. Andrew Moulden
https://www.amazon.com/Medical-Doctors-Opposed-Forced-Vaccinations-ebook/dp/B00YVU2K0I/ref=pd_sim_351_1
http://healthimpactnews.com/2014/gardasil-vaccine-one-more-girl-dead/
Vademecum.es
Papilomavirus (tipos humanos 6, 11, 16, 18, 31, 33, 45, 52, 58)
New england latest post.
http://www.nejm.org/medical-research/viral-infections#qs=%3Fsubtopic%3Dviral-infections%26category%3Dresearch
http://www.nejm.org/doi/full/10.1056/NEJMoa1612296
SOURCE INFORMATION
From the Department of Epidemiology Research, Statens Serum Institut, Copenhagen (N.M.S., B.P., D.M.-N., H.S., A.H.); and the Clinical Epidemiology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm (B.P.).
Address reprint requests to Dr. Scheller at the Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark, or a
nims@ssi.dk.
Informacion negativa técnica.
http://www.nhs.uk/Conditions/vaccinations/Pages/hpv-vaccine-cervarix-gardasil-side-effects.aspx
HPV vaccine side effects - Vaccinations - NHS Choices
Find out the side effects of the HPV vaccine and how common they are plus how to report a vaccine side effect.
nhs.uk
http://www.nhs.uk/Conditions/vaccinations/Pages/reporting-side-effects.aspx
CDC opinion on vaccine safety
https://www.cdc.gov/vaccinesafety/research/publications/index.html
Vaccine Safety Publications Publications | Research | Vaccine Safety | CDC
Access publications on vaccine safety by specific safety system, safety topic, and year.
cdc.gov
IN SPANISH
https://www.cdc.gov/vaccines/vpd-vac/hpv/downloads/dis-HPV-color-office-sp.pdf
https://www.cdc.gov/vaccines/parents/diseases/teen/hpv-indepth-color-sp.pdf
www.cdc.gov
cdc.gov
This document provides information on immunizations for women in 2014. It discusses myths versus facts about vaccines, explains that vaccines do not cause autism or the diseases they protect against. It addresses safety and effectiveness of the influenza and Tdap vaccines during pregnancy. It recommends that all pregnant women receive the inactivated influenza vaccine each year from 27-36 weeks of pregnancy and the Tdap vaccine in each pregnancy. Minor and temporary side effects are common with vaccines while severe reactions are extremely rare.
The document provides guidelines for vaccinating pregnant women from the Advisory Committee on Immunization Practices. It recommends that inactivated vaccines are generally safe during pregnancy when the risk of disease exposure is high. Live vaccines are contraindicated due to theoretical risk to the fetus. It provides vaccine-specific recommendations, noting some can be used if benefits outweigh risks or in high risk situations, while others are not recommended or contraindicated during pregnancy.
Overview presentation: The Burden of Group B Streptococcus Worldwide for Preg...Anjuli Borgonha
This document summarizes a presentation on estimating the global burden of Group B Streptococcus (GBS) disease for pregnant women, stillbirths, and children. It describes the need to estimate the worldwide impact of this leading cause of neonatal infections in high-income countries. A multi-step compartmental model was used to estimate GBS cases, deaths, and disability. Extensive data searches and expert reviews were conducted to gather all available data on GBS colonization, disease outcomes, and risk factors. The challenges of differences in data collection methods and healthcare access across countries are acknowledged. The overall aim is to inform global public health policy, such as the potential development of a maternal GBS vaccine.
Since no study has claimed the relationship between the corona vaccine and menstrual cycle, there is no certain cause for the same. However, some experts suggest the following possible causes.
This document discusses the experience with the PCV7 pneumococcal conjugate vaccination in children considered "at risk". It finds that:
1) PCV7 vaccination effectively reduces the risk of invasive pneumococcal disease (IPD) in children under 2 years old by 68-84.5%.
2) High risk groups recommended for vaccination include infants, toddlers up to 24 months, and children with conditions like sickle cell disease or HIV that increase risk of IPD.
3) The vaccination schedule involves a 2 or 3 dose primary series plus a booster, depending on age started, to provide high immunogenicity and efficacy against IPD above 80% in clinical trials.
Pequeño análisis sobre la necesidad de Vacunar y su impacto en la sociedad en...Dr. Manuel Concepción
Debo vacunar a mi hijo.doc
https://xemide-new-american-institute.tumblr.com/
https://www.youtube.com/watch?v=S1zaOUV0BTg
@newaericaninstitutexcupware
https://twitter.com/grow_follow
"Brian Shilhavy"
Dr. Andrew Moulden
https://www.amazon.com/Medical-Doctors-Opposed-Forced-Vaccinations-ebook/dp/B00YVU2K0I/ref=pd_sim_351_1
http://healthimpactnews.com/2014/gardasil-vaccine-one-more-girl-dead/
Vademecum.es
Papilomavirus (tipos humanos 6, 11, 16, 18, 31, 33, 45, 52, 58)
New england latest post.
http://www.nejm.org/medical-research/viral-infections#qs=%3Fsubtopic%3Dviral-infections%26category%3Dresearch
http://www.nejm.org/doi/full/10.1056/NEJMoa1612296
SOURCE INFORMATION
From the Department of Epidemiology Research, Statens Serum Institut, Copenhagen (N.M.S., B.P., D.M.-N., H.S., A.H.); and the Clinical Epidemiology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm (B.P.).
Address reprint requests to Dr. Scheller at the Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark, or a
nims@ssi.dk.
Informacion negativa técnica.
http://www.nhs.uk/Conditions/vaccinations/Pages/hpv-vaccine-cervarix-gardasil-side-effects.aspx
HPV vaccine side effects - Vaccinations - NHS Choices
Find out the side effects of the HPV vaccine and how common they are plus how to report a vaccine side effect.
nhs.uk
http://www.nhs.uk/Conditions/vaccinations/Pages/reporting-side-effects.aspx
CDC opinion on vaccine safety
https://www.cdc.gov/vaccinesafety/research/publications/index.html
Vaccine Safety Publications Publications | Research | Vaccine Safety | CDC
Access publications on vaccine safety by specific safety system, safety topic, and year.
cdc.gov
IN SPANISH
https://www.cdc.gov/vaccines/vpd-vac/hpv/downloads/dis-HPV-color-office-sp.pdf
https://www.cdc.gov/vaccines/parents/diseases/teen/hpv-indepth-color-sp.pdf
www.cdc.gov
cdc.gov
This document provides information on immunizations for women in 2014. It discusses myths versus facts about vaccines, explains that vaccines do not cause autism or the diseases they protect against. It addresses safety and effectiveness of the influenza and Tdap vaccines during pregnancy. It recommends that all pregnant women receive the inactivated influenza vaccine each year from 27-36 weeks of pregnancy and the Tdap vaccine in each pregnancy. Minor and temporary side effects are common with vaccines while severe reactions are extremely rare.
The document provides guidelines for vaccinating pregnant women from the Advisory Committee on Immunization Practices. It recommends that inactivated vaccines are generally safe during pregnancy when the risk of disease exposure is high. Live vaccines are contraindicated due to theoretical risk to the fetus. It provides vaccine-specific recommendations, noting some can be used if benefits outweigh risks or in high risk situations, while others are not recommended or contraindicated during pregnancy.
Overview presentation: The Burden of Group B Streptococcus Worldwide for Preg...Anjuli Borgonha
This document summarizes a presentation on estimating the global burden of Group B Streptococcus (GBS) disease for pregnant women, stillbirths, and children. It describes the need to estimate the worldwide impact of this leading cause of neonatal infections in high-income countries. A multi-step compartmental model was used to estimate GBS cases, deaths, and disability. Extensive data searches and expert reviews were conducted to gather all available data on GBS colonization, disease outcomes, and risk factors. The challenges of differences in data collection methods and healthcare access across countries are acknowledged. The overall aim is to inform global public health policy, such as the potential development of a maternal GBS vaccine.
Since no study has claimed the relationship between the corona vaccine and menstrual cycle, there is no certain cause for the same. However, some experts suggest the following possible causes.
This document discusses maternal immunization against pertussis (whooping cough) using the Tdap vaccine. It provides information on:
1) The benefits of maternal immunization for both mother and infant by boosting maternal antibodies and protecting newborns who are most at risk of severe disease.
2) Pertussis epidemiology and increasing rates globally, especially in adolescents and adults. Infants under 6 months face the greatest risk of hospitalization and death from pertussis.
3) Clinical trial data demonstrating the safety of Tdap vaccination during pregnancy with no adverse effects on pregnancy or newborn outcomes. Maternal immunization provides the greatest protection for young infants.
Rotavirus vaccines in India - Whats new in 2021 Gaurav Gupta
This document provides information on Rotavirus gastroenteritis (RVGE) and rotavirus vaccines in India, with a focus on vaccine 116E. It discusses how RVGE is a major cause of childhood diarrhea and mortality in India. It summarizes clinical trial results showing the 116E vaccine is effective at preventing severe RVGE, has a good safety profile with no increased risk of intussusception compared to other vaccines, and provides broad protection against circulating rotavirus strains in India. Phase 3 and 4 trials demonstrated 116E is well-tolerated and effective in preventing severe RVGE in Indian children when administered in a 3-dose schedule.
Meningococcal vaccination needed in india july 2016Gaurav Gupta
Menactra Meningococcal Conjugate Vaccine in India, is it really needed?
July 2016 Sanofi Pasteur Talk for Pediatricians, Child Specialist Doctors related to Vaccination, Immunization etc.
Immunization for INDIAN Adolescents Dr. Jyoti Agarwal Dr. Sharda Jain Dr. J...Lifecare Centre
Vaccinations are among the greatest public health achievements of the 20th century
First recorded in 1890-95
Imminization is the action of making a person immune to infection, typically by inoculation
Immunization prevents disability & death from infectious diseases
It also helps control the spread of infections within communities
Early treatment of perinatally HIV-infected infants provides a unique opportunity to implement immunotherapeutic strategies to prolong viral remission without lifelong antiretroviral therapy. Infants treated within days of birth have a very small viral reservoir, high levels of HIV-resistant naive T cells, and an unparalleled ability to regenerate their immune system. This population is ideal for investigating immune-based therapies that could lead to viral control without medication. Successful strategies could change how HIV infection is managed for children worldwide.
Preterm immunisation 2018 - Dr Karthik Nageshkarthiknagesh
This document discusses vaccination in preterm infants. It notes that preterm infants are at higher risk of morbidity and mortality from vaccine-preventable diseases. However, vaccination of preterms is often delayed. The document summarizes evidence that preterm infants can mount protective immune responses when vaccinated according to their chronological age, regardless of gestational age or birth weight. It addresses specific concerns about the safety and efficacy of various vaccines in preterm populations such as BCG, polio, hepatitis B, pertussis and others. Overall, the document advocates for vaccinating medically stable preterm infants according to routine schedules in order to provide them protection from serious diseases.
Clinical Guideline on COVID-19 Vaccination for Adolescents (12 – 17 years)
Prepared by Dr Nik Khairulddin Nik Yusoff, Paediatrician at Hospital Raja Perempuan Zainab II
Delhi gynaecologist forum Guidelines on Immunization for Indian Adolescent...Lifecare Centre
The document provides guidelines on immunizing Indian adolescents. It recommends that all 11-12 year olds receive the Tdap, meningococcal, HPV, and influenza vaccines. HPV vaccination is especially important for adolescent girls to protect against cancers later in life. Barriers to adolescent immunization include lack of education, costs, and provider challenges. Improving rates requires taking advantage of all healthcare visits, improving communication, using reminder systems, and adopting standardized immunization processes. Physicians play a key role in educating, recommending vaccines, and changing attitudes.
This document summarizes a study on bacterial contamination found in powdered infant formula. The key points are:
- Testing found that over 50% of powdered formula samples from 35 countries were contaminated with Enterobacteria bacteria.
- Several outbreaks of illness in neonatal intensive care units were linked to formula contaminated with Salmonella or Enterobacter sakazakii bacteria before the formula was opened.
- In response, some formula brands recalled batches and health authorities issued safety warnings, but more needs to be done to inform consumers directly of the risks and encourage stricter manufacturing practices.
Hep a Live & Inactivated vaccines in IndiaGaurav Gupta
dIAP presentation for GSK - Havrix and comparison of Live and inactivated Hepatitis A vaccines in Dec 2020.. Online discussion about the various Hep A vaccines available and their pros and cons
Prevenar e cme june 2020 & FAQs & COVID Clinic QuestionsGaurav Gupta
Lockdown E-CME & Webinars - this one is on Pfizer vaccine - Prevenar,
We have also discussed the common questions on Pneumonia & how to run clinical practice during COVID shutdown
This document provides guidelines for managing pregnancy and childbirth during the COVID-19 pandemic. It recommends social distancing, hand hygiene, respiratory hygiene, avoiding touching the face, and maintaining distance to prevent infection. It provides guidance on testing, treatment, and care of pregnant women with COVID-19, including arranging isolation facilities in hospitals and ensuring access to termination services and reproductive healthcare. It also outlines precautions healthcare workers should take, such as distancing, proper use of personal protective equipment, and chemoprophylaxis for those exposed to COVID-19 patients.
This document discusses vaccination during pregnancy. It begins by outlining the success of maternal immunization and different types of vaccines. It then covers immunization before, during, and after pregnancy. Vaccines recommended during pregnancy include tetanus, diphtheria, pertussis (Tdap), and inactivated influenza vaccines. Live attenuated vaccines are generally contraindicated due to theoretical risk to the fetus. Postpartum, women should receive any recommended vaccines not administered during pregnancy. Vaccines are an effective way to prevent infectious diseases posing risks to mothers and newborns.
IVIg has been shown to reduce the risk of bacterial sepsis and other serious infections in preterm and low birth weight infants based on multiple randomized controlled trials. It provides passive immunity through IgG antibodies transferred from donors. While it reduces infection rates, IVIg does not lower mortality or rates of other complications. The decision to use prophylactic IVIg depends on weighing the costs against the 3-4% reduction in infection seen in trials. Further research is not needed to confirm IVIg's efficacy but rather to develop alternative prevention methods.
ppt on Tdap vaccination by Dr. Alka Mukherjee - Mukherjee HospitalMukherjeeHospital
The document discusses TDAP vaccination in maternal immunization. It recommends vaccinating pregnant women with the TDAP vaccine between 27-36 weeks of gestation to protect both mother and infant from pertussis. Vaccinating during pregnancy allows for passive transfer of antibodies from mother to fetus, providing protection for the infant in early life when they are most vulnerable to complications from pertussis infection. Studies show the TDAP vaccine is safe in pregnancy and results in adequate immune response and antibody transfer to protect both mother and infant. Global and local health bodies recommend TDAP vaccination during pregnancy as the optimal strategy.
Choosing a pneumococcal vaccine - wisely.. Prevenar in Indian contextGaurav Gupta
Choosing a pneumococcal vaccine - wisely.. Prevenar in Indian context latest studies as of July 2018,
Which vaccine is the best in India as of 2018, latest studies and scientific data
Today we all live and work in the Internet Century, where technology is roiling the business landscape, and the pace of change is only accelerating.
In their new book How Google Works, Google Executive Chairman and ex-CEO Eric Schmidt and former SVP of Products Jonathan Rosenberg share the lessons they learned over the course of a decade running Google.
Covering topics including corporate culture, strategy, talent, decision-making, communication, innovation, and dealing with disruption, the authors illustrate management maxims with numerous insider anecdotes from Google’s history.
In an era when everything is speeding up, the best way for businesses to succeed is to attract smart-creative people and give them an environment where they can thrive at scale. How Google Works is a new book that explains how to do just that.
This is a visual preview of How Google Works. You can pick up a copy of the book at www.howgoogleworks.net
This document discusses maternal immunization against pertussis (whooping cough) using the Tdap vaccine. It provides information on:
1) The benefits of maternal immunization for both mother and infant by boosting maternal antibodies and protecting newborns who are most at risk of severe disease.
2) Pertussis epidemiology and increasing rates globally, especially in adolescents and adults. Infants under 6 months face the greatest risk of hospitalization and death from pertussis.
3) Clinical trial data demonstrating the safety of Tdap vaccination during pregnancy with no adverse effects on pregnancy or newborn outcomes. Maternal immunization provides the greatest protection for young infants.
Rotavirus vaccines in India - Whats new in 2021 Gaurav Gupta
This document provides information on Rotavirus gastroenteritis (RVGE) and rotavirus vaccines in India, with a focus on vaccine 116E. It discusses how RVGE is a major cause of childhood diarrhea and mortality in India. It summarizes clinical trial results showing the 116E vaccine is effective at preventing severe RVGE, has a good safety profile with no increased risk of intussusception compared to other vaccines, and provides broad protection against circulating rotavirus strains in India. Phase 3 and 4 trials demonstrated 116E is well-tolerated and effective in preventing severe RVGE in Indian children when administered in a 3-dose schedule.
Meningococcal vaccination needed in india july 2016Gaurav Gupta
Menactra Meningococcal Conjugate Vaccine in India, is it really needed?
July 2016 Sanofi Pasteur Talk for Pediatricians, Child Specialist Doctors related to Vaccination, Immunization etc.
Immunization for INDIAN Adolescents Dr. Jyoti Agarwal Dr. Sharda Jain Dr. J...Lifecare Centre
Vaccinations are among the greatest public health achievements of the 20th century
First recorded in 1890-95
Imminization is the action of making a person immune to infection, typically by inoculation
Immunization prevents disability & death from infectious diseases
It also helps control the spread of infections within communities
Early treatment of perinatally HIV-infected infants provides a unique opportunity to implement immunotherapeutic strategies to prolong viral remission without lifelong antiretroviral therapy. Infants treated within days of birth have a very small viral reservoir, high levels of HIV-resistant naive T cells, and an unparalleled ability to regenerate their immune system. This population is ideal for investigating immune-based therapies that could lead to viral control without medication. Successful strategies could change how HIV infection is managed for children worldwide.
Preterm immunisation 2018 - Dr Karthik Nageshkarthiknagesh
This document discusses vaccination in preterm infants. It notes that preterm infants are at higher risk of morbidity and mortality from vaccine-preventable diseases. However, vaccination of preterms is often delayed. The document summarizes evidence that preterm infants can mount protective immune responses when vaccinated according to their chronological age, regardless of gestational age or birth weight. It addresses specific concerns about the safety and efficacy of various vaccines in preterm populations such as BCG, polio, hepatitis B, pertussis and others. Overall, the document advocates for vaccinating medically stable preterm infants according to routine schedules in order to provide them protection from serious diseases.
Clinical Guideline on COVID-19 Vaccination for Adolescents (12 – 17 years)
Prepared by Dr Nik Khairulddin Nik Yusoff, Paediatrician at Hospital Raja Perempuan Zainab II
Delhi gynaecologist forum Guidelines on Immunization for Indian Adolescent...Lifecare Centre
The document provides guidelines on immunizing Indian adolescents. It recommends that all 11-12 year olds receive the Tdap, meningococcal, HPV, and influenza vaccines. HPV vaccination is especially important for adolescent girls to protect against cancers later in life. Barriers to adolescent immunization include lack of education, costs, and provider challenges. Improving rates requires taking advantage of all healthcare visits, improving communication, using reminder systems, and adopting standardized immunization processes. Physicians play a key role in educating, recommending vaccines, and changing attitudes.
This document summarizes a study on bacterial contamination found in powdered infant formula. The key points are:
- Testing found that over 50% of powdered formula samples from 35 countries were contaminated with Enterobacteria bacteria.
- Several outbreaks of illness in neonatal intensive care units were linked to formula contaminated with Salmonella or Enterobacter sakazakii bacteria before the formula was opened.
- In response, some formula brands recalled batches and health authorities issued safety warnings, but more needs to be done to inform consumers directly of the risks and encourage stricter manufacturing practices.
Hep a Live & Inactivated vaccines in IndiaGaurav Gupta
dIAP presentation for GSK - Havrix and comparison of Live and inactivated Hepatitis A vaccines in Dec 2020.. Online discussion about the various Hep A vaccines available and their pros and cons
Prevenar e cme june 2020 & FAQs & COVID Clinic QuestionsGaurav Gupta
Lockdown E-CME & Webinars - this one is on Pfizer vaccine - Prevenar,
We have also discussed the common questions on Pneumonia & how to run clinical practice during COVID shutdown
This document provides guidelines for managing pregnancy and childbirth during the COVID-19 pandemic. It recommends social distancing, hand hygiene, respiratory hygiene, avoiding touching the face, and maintaining distance to prevent infection. It provides guidance on testing, treatment, and care of pregnant women with COVID-19, including arranging isolation facilities in hospitals and ensuring access to termination services and reproductive healthcare. It also outlines precautions healthcare workers should take, such as distancing, proper use of personal protective equipment, and chemoprophylaxis for those exposed to COVID-19 patients.
This document discusses vaccination during pregnancy. It begins by outlining the success of maternal immunization and different types of vaccines. It then covers immunization before, during, and after pregnancy. Vaccines recommended during pregnancy include tetanus, diphtheria, pertussis (Tdap), and inactivated influenza vaccines. Live attenuated vaccines are generally contraindicated due to theoretical risk to the fetus. Postpartum, women should receive any recommended vaccines not administered during pregnancy. Vaccines are an effective way to prevent infectious diseases posing risks to mothers and newborns.
IVIg has been shown to reduce the risk of bacterial sepsis and other serious infections in preterm and low birth weight infants based on multiple randomized controlled trials. It provides passive immunity through IgG antibodies transferred from donors. While it reduces infection rates, IVIg does not lower mortality or rates of other complications. The decision to use prophylactic IVIg depends on weighing the costs against the 3-4% reduction in infection seen in trials. Further research is not needed to confirm IVIg's efficacy but rather to develop alternative prevention methods.
ppt on Tdap vaccination by Dr. Alka Mukherjee - Mukherjee HospitalMukherjeeHospital
The document discusses TDAP vaccination in maternal immunization. It recommends vaccinating pregnant women with the TDAP vaccine between 27-36 weeks of gestation to protect both mother and infant from pertussis. Vaccinating during pregnancy allows for passive transfer of antibodies from mother to fetus, providing protection for the infant in early life when they are most vulnerable to complications from pertussis infection. Studies show the TDAP vaccine is safe in pregnancy and results in adequate immune response and antibody transfer to protect both mother and infant. Global and local health bodies recommend TDAP vaccination during pregnancy as the optimal strategy.
Choosing a pneumococcal vaccine - wisely.. Prevenar in Indian contextGaurav Gupta
Choosing a pneumococcal vaccine - wisely.. Prevenar in Indian context latest studies as of July 2018,
Which vaccine is the best in India as of 2018, latest studies and scientific data
Today we all live and work in the Internet Century, where technology is roiling the business landscape, and the pace of change is only accelerating.
In their new book How Google Works, Google Executive Chairman and ex-CEO Eric Schmidt and former SVP of Products Jonathan Rosenberg share the lessons they learned over the course of a decade running Google.
Covering topics including corporate culture, strategy, talent, decision-making, communication, innovation, and dealing with disruption, the authors illustrate management maxims with numerous insider anecdotes from Google’s history.
In an era when everything is speeding up, the best way for businesses to succeed is to attract smart-creative people and give them an environment where they can thrive at scale. How Google Works is a new book that explains how to do just that.
This is a visual preview of How Google Works. You can pick up a copy of the book at www.howgoogleworks.net
A presentation on barriers in effective communication. This includes the importance and characteristics in brief. The barriers are divided into sectors and given as well as the ways to overcome the barriers are also mentioned.
Attitudinal barriers to communication include abstracting, emotional editing, and stereotypes that form from opinions and feelings. Abstracting involves selective hearing without details, emotional editing bases understanding on feelings toward people or topics, and stereotypes create fixed opinions. These barriers can be broken by being a good listener, responding thoughtfully instead of reacting, expressing oneself while also letting others speak, being honest, and listening to one's inner self. Overcoming attitudinal barriers improves communication.
How Managers Can Overcome 3 Systemic Barriers to Effective CommunicationNMC Strategic Manager
In addition to technical barriers, there may be systemic barriers in your organization that prevent effective communication. Learn 3 major barriers and how managers can overcome them.
This document discusses various barriers to effective communication. It identifies several types of barriers, including language barriers, physiological barriers, physical barriers, systematic barriers, attitudinal barriers, perceptual barriers, emotional barriers, cultural barriers, and noise in the communication channel. Specific barriers mentioned are the use of jargon, emotional taboos, lack of attention, differences in perception, physical disabilities, language differences, expectations and prejudices, and cultural differences in communication norms. Ways to overcome some of these barriers include using face-to-face communication, recognizing different perspectives, building trust, understanding different cultural communication styles, soliciting feedback, and practicing active listening.
The document contains identifying information about Dhanraj Vaghela including his name, branch of study, semester, and enrollment number. It discusses how knowing the purpose of an activity, such as a presentation, helps the presenter plan and prepare by being clear on the reason for doing it. The main purpose of any presentation is to get the message across to the listener, and understanding the local presentation involves having complete knowledge about the audience and location.
The document provides tips for effective body language and clothing choices for presentations. For body language, it recommends maintaining eye contact, using natural gestures, varying vocal tones, and keeping an upright but relaxed posture. For clothing, it states that business or business casual attire is usually appropriate, depending on the situation. Men should wear well-tailored suits or casual wear, and women's clothes should fit properly without being too tight. The overall message is that presenters should dress professionally while keeping body language and appearance relaxed and natural to engage the audience.
10 Tips for Making Beautiful Slideshow Presentations by www.visuali.seEdahn Small
1. Know your goal | make each slide count
2. Plan it out | in some detail
3. Avoid templates | they have the uglies
4. Choose a color scheme | 4 colors, 1 accent
5. Choose a font scheme | match tone
6. Choose a layout scheme | comprehension
7. Use images (wisely) | they’re more memorable
8. 15 words per slide | this slide had 16 words
9. Play with typography | impact, interest, hierarchy
10. Don’t overdo it | white space
Hope you enjoy!
SEE MORE OF MY WORK: http://www.visuali.se
The Quick And Dirty Guide To Creating Blog Posts That Your Audience CravesDominique Jackson
You've been reading about the importance of blogging for a long time. You might have started out with a blog post every now and then, but never got any traction. Most people fail at blogging because they're creating the wrong type of content.
This presentation will show you how to create blog posts that your target audience CRAVES and is STARVING for. The type of content that people look for when they're further into the buying process. And the best part? It's just a simple 3 step process!
Presentation on formal vs informal communication Md. Reajul Kabir
Communication is the sharing of information between individuals or groups to reach a common understanding. There are formal and informal styles of communication that are each appropriate depending on the situation. Formal communication follows official rules and includes downward, upward, and horizontal messages within an organization. Informal communication occurs spontaneously between people of varying statuses and helps indicate employee concerns and satisfaction. Both formal and informal communication are necessary for effective information sharing in organizations.
How to format powerpoint presentation slidesmikejeffs
How to format PowerPoint presentation slides. Tips and tricks within Microsoft PowerPoint to use to arrange your slides including; view type, grids, guidelines and themes.
The document discusses the four main types of communication: verbal communication, non-verbal communication, written communication, and visual communication. It provides details on each type, including that verbal communication involves speaking, non-verbal communication is physical ways of communicating without words, written communication includes business letters and newsletters, and visual communication displays information visually through images, signs, and electronic forms like video. The document also shares information on specific communication methods like public speaking, body language, email, and the internet.
How to create a basic power point presentationjoluisae
This document provides instructions for creating a basic PowerPoint presentation in 9 steps:
1) Open PowerPoint and save your project, saving often to prevent data loss.
2) Create a title slide with the presentation title and subtitle.
3) Choose a slide design template.
4) Add new slides and edit the slide layout.
5) Add text to slides by adjusting font settings.
6) Add pictures to slides by inserting images from your computer.
7) Create multiple slides by following steps 4-6.
8) Add slide transitions by selecting different transition styles and settings.
9) Repeat step 8 to add transitions to other slides and preview the completed presentation.
This document provides 20 quotes from historical figures to inspire creative genius. The quotes encourage thinking outside the box, taking risks, being curious, breaking rules, and gaining an unfair advantage through creativity. They emphasize trusting instincts, changing the world through committed groups, and navigating without a map in creative pursuits. The document aims to banish creative roadblocks by sharing inspirational thoughts on creativity.
The document discusses the marketing mix, also known as the 4Ps of marketing - product, price, promotion, and place. It explains that the marketing mix refers to the combination of marketing activities and tactics that a company uses to meet the needs of its target market. Each of the 4Ps is then defined in 1-2 sentences, with price referring to how a product is priced, place referring to distribution channels, product referring to the product or service itself, and promotion referring to marketing communication methods. Students are then assigned to groups to focus on applying one of the 4Ps to a specific product.
This presentation aims at helping the pediatric trainees and practitioners to brush up their knowledge in Immunization. The schedule is based on the Universal Immunisation Programme. I have tried to cover as much as possible in terms of individual vaccines and hope it is beneficial to the reader.
This document discusses vaccination recommendations for adolescents, preconception, and during pregnancy. It provides guidance on routine vaccinations such as Tdap, HPV, influenza, and meningococcal vaccines for adolescents. It also discusses catch-up vaccinations for hepatitis B, MMR, varicella, hepatitis A, and typhoid. The effectiveness and schedules for 2-dose HPV vaccination in adolescents is reviewed. Preconception vaccination guidance emphasizes determining immune status for rubella, varicella and hepatitis B and vaccinating susceptible women.
This document provides vaccination schedules and guidelines for children from various health organizations. It begins by outlining the vaccination schedule for children in India from birth through age 18-19 months. It then discusses vaccination schedules from UNICEF and provides details on specific vaccines such as BCG, DTwP/DTaP, polio, hepatitis B, and others. The document discusses administration of vaccines, contraindications, side effects of the HPV vaccine, and more. It provides comprehensive information on vaccination of children.
This presentation aims at helping the pediatric trainees and practitioners to brush up their knowledge in Immunization. The schedule is based on the Universal Immunisation Programme. I have tried to cover as much as possible in terms of individual vaccines and hope it is beneficial to the reader.
This document discusses various preventive medicine topics including vaccines for MMR, influenza, meningococcal disease, pneumococcal disease, hepatitis A, hepatitis B, polio, and varicella. It provides information on indications, contraindications, dosing schedules, and evidence of immunity for each vaccine. Recommendations are given for vaccinating special populations including HIV patients, the elderly, those with chronic illnesses, international travelers, and health care workers.
Dr. Pradeep Katwal presented on adult immunization. He discussed how vaccines have led to the eradication of smallpox and near eradication of diseases like diphtheria. He reviewed the immunological basis of vaccines and highlighted various vaccines recommended for adults including influenza, pneumococcal, hepatitis A/B, HPV and herpes zoster vaccines. Adult immunization is important to reduce the burden of vaccine-preventable diseases and protect high risk groups.
The document discusses adult immunization and summarizes recommendations for various vaccines. It provides an overview of the history and pioneers of immunization like Jenner and Pasteur. Data is presented showing the success of vaccines in reducing cases of diseases like smallpox, diphtheria, and invasive pneumococcal disease. Recommendations are outlined for vaccines including influenza, pneumococcal, hepatitis A/B, meningococcal, MMR, HPV, Tdap, herpes zoster and others. Contraindications and special populations are also mentioned.
Dr Swati Rajagopal_ ADULT VACCINATION.pptxVandanaVats8
This document discusses adult immunization guidelines in India. It covers several common vaccines recommended for adults such as the influenza, tetanus/diphtheria/pertussis, pneumococcal, hepatitis A and B, herpes zoster, and HPV vaccines. For each vaccine, it describes the types available, indications for use, dosage, schedule, precautions, and high-risk groups. The document emphasizes that while childhood immunization is widespread in India, awareness and uptake of adult vaccines remains low despite the significant disease burden they can prevent.
D.G.F. Guidelines on Immunization for Indian Adolescents Girls DGFPublicAwareness
The document provides guidelines on immunization for Indian adolescents. It discusses how immunization is important not just for infants and children, but adolescents as well. It recommends vaccines for different age groups, including Tdap, HPV, meningococcal, and annual influenza vaccines for ages 11-12. The guidelines emphasize delivering immunization services to adolescents to protect their health and future. Barriers to adolescent immunization rates are also addressed, along with ways providers can improve communication and access to help more adolescents get recommended vaccines.
Newer Vaccines were presented. Key points include:
1) Vaccines work by exposing the immune system to agents that resemble viruses or bacteria without causing illness, allowing the body to develop immunity.
2) Newer vaccines include pentavalent, fIPV, MR, and dengue vaccines that have been added to national immunization programs.
3) Other newer vaccines discussed include malaria, Japanese encephalitis, cholera, HIV, leprosy, HPV, and cancer vaccines that target specific diseases.
LAIV in India - Should we use it? Sep 2014Gaurav Gupta
LAIV Nasovac S by Serum Institute of India, should it be used in India?
Influenza vaccine, Flu, India, Live, Inactivated, Children, injection, vaccine, asthma
Newer vaccines provide protection against additional diseases. The document discusses several newer vaccines including dengue, pentavalent, HPV, measles-rubella (MR), Japanese encephalitis (JE), oral cholera, HIV, malaria, leprosy, tuberculosis, and cancer vaccines. Many of these vaccines have been added to national immunization programs in recent decades to further reduce mortality from vaccine-preventable diseases.
Adult immunization is important but lagging in India due to various factors like lack of universal adult immunization programs, short-term vaccine induced immunity, and lack of awareness among adults. Several vaccines are available for adults including influenza, hepatitis A and B, tetanus-diphtheria-pertussis, herpes zoster, HPV, pneumococcal, and meningococcal vaccines. Pregnant women should receive Tdap and influenza vaccines. Immunocompromised adults may receive inactivated vaccines depending on their condition. Travel vaccines like yellow fever are also important for international travel. Increasing awareness among healthcare providers and adults is key to improving adult immunization rates.
1) GSK produces vaccines for diseases like pneumonia, polio, rotavirus, cervical cancer and others. Their vaccines have helped prevent up to 3 million deaths and disability in 750,000 children annually.
2) GSK's cervical cancer vaccine, Cervarix, is dedicated to preventing cervical cancer. Clinical trials showed it has nearly 100% efficacy against HPV types 16 and 18, which cause over 50% of cervical cancer cases. It also has efficacy against other high-risk HPV types and has a good safety profile.
3) GSK provides holistic support for vaccination programs including cold chain management, training, advocacy, and monitoring to help ensure vaccines are effectively delivered and utilized. They aim
Recommended Immunization Schedules For Children And Adolescents,DJ CrissCross
The document outlines the recommended immunization schedules for children and adolescents in the United States in 2007, including details on the vaccines, ages for administration, dosage information, efficacy of the vaccines, and notable changes from previous years such as the addition of rotavirus and HPV vaccines. It provides guidance on the optimal timing and procedures for administering 16 different vaccines to help protect against various diseases.
The document provides recommendations for adult immunization schedules in the United States for 2014. It includes 2 figures: Figure 1 lists recommended vaccines by age group from 19-21 years to 65 years and older. Figure 2 lists medical indications when additional vaccines may be recommended. Key recommendations include an annual influenza vaccine for all adults, a one-time Tdap booster followed by Td every 10 years, HPV vaccination through age 26, and consideration of PCV13, PPSV23, and hepatitis B vaccines for adults with certain medical conditions.
Based on the current NACO guidelines for prevention of parent to child transmission of HIV in India. Also describes the medication, testing and followup of children born to HIV positive mothers.
This document presents the 2017 adult and pediatric immunization schedule as recommended by the Advisory Committee on Immunization Practices and approved by the Centers for Disease Control and Prevention. It consists of recommendations for routine vaccines for adults by age and medical condition/indication, including important footnotes on vaccine-specific considerations. The schedule aims to provide healthcare professionals with current evidence-based guidance on immunization for adults and children.
The document discusses adult immunization strategies in India. It notes there is a lack of consensus on optimal adult immunization strategies in developing countries like India due to a lack of reliable epidemiological data, efficacy and safety data of vaccination strategies, and data on monitoring immunization adequacy. The document provides guidance on recommended vaccines for different adult groups and schedules for vaccines including tetanus, diphtheria, pertussis, hepatitis A, hepatitis B, HPV, influenza, measles, mumps, rubella, varicella, herpes zoster and pneumococcal vaccines.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14...Donc Test
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
1. Adult Vaccinations: An Update
Bernard J Dunn School of Pharmacy
Shenandoah University
03/13/2013
2. Objectives
● Evaluate pneumococcal vaccine Menveo®
● Compare Menveo® with other meningococcal
vaccines
● Provide new Advisory Committee on Immunization
Practices (ACIP) recommendations for vaccinations
3. Menveo®
● FDA approved 2010 for active immunization against
invasive meningococcal disease caused by Neisseria
meningitidis serogroups: A, C, Y and W-135.
● Initially, Menveo® was only indicated for use for persons
11-55 years old. Coverage expanded in June 2011 to
include children ages 2-10.
● Administered as a single dose IM.
Menveo package insert, 2011
4. Menveo - Efficacy
Clinical Trial for the safety and efficacy of Menveo in children 2-10 years old
study design
MENVEO in subjects 2-55 years old was assessed by comparing
the serum bactericidal antibody (SBA) responses to immunization
with Menveo®
● Two randomized, multicenter, active controlled clinical studies
comparing the hSBA responses following one dose of Menveo® or
Menactra®.
● Primary endpoint - hSBA seroresponse to each serogroup 28 days after
vaccination. Seroresponse was defined as:
- post vaccination hSBA titer of ≥1:8 for subjects with a baseline hSBA titer of <1:4 OR
at least 4-fold higher than baseline titers for subjects with a pre-vaccination hSBA titer ≥1:4.
Menveo package insert, 2011
5. Menveo - Efficacy
● Population – (1170) Menveo® and (1161)
Menactra®
● Demographics were similar between the two
groups
6. Menveo - Efficacy
● Results (28 days after vaccination)
Ages 2-5 (seroresponse in %)
Menveo® was non-inferior to Menactra® for subjects with a
seroresponse for serogroups C (60 vs. 56), W-135 (72 vs. 58) and Y
(66 vs. 45) , but not for serogroup A (72 vs. 77)
Ages 6-10
Menveo® was non-inferior to Menactra® for subjects with a
seroresponse for serogroups C(63 vs. 57), W-135 (57 vs. 44) and Y
(58 vs. 39) , but not for serogroup A (77 vs. 83)
7. Menveo - Efficacy
Ages 11-18
Menveo® was non-inferior to Menactra in all four serogroups A
(75 vs. 66), C (76 vs. 73), W-135(75-63) and Y(68 vs. 41) for the
proportion of subjects with a seroresponse.
Ages 19-55
Menveo® was non-inferior to Menactra in all four serogroups A
(67 vs. 68), C (68 vs. 60), W-135(50-41) and Y(56 vs. 40) for the
proportion of subjects with a seroresponse.
8. Menveo® - Safety
Study design
● Ages 2-10: four randomized clinical trials.
● Population - 3181 subjects received Menveo® and 2116 received either Menomune®
or Menactra®.
● 51% male in both populations and mean age was 5.2 years old.
● Safety of a second dose of Menveo administered 2 months following a first dose was
assessed in 351 children ages 2-5 years old.
● Ages 11-55: five randomized trials.
● Population - 5286 subjects received Menveo® , 209 subjects received Menomune®
and 1757 patients Menactra®.
● Average ages on Menveo® were 23.5 years (SD 12.9 years), Menacta® 29.2 years (SD
13.4), Menomune® 14.2 years (sd 1.8 years)
● Subjects were monitored for 7 days following vaccinations, 28 days for adverse
events and serious adverse events 6 months after vaccination.
9. Menveo
● Results - Adverse reactions
Ages 2-10
Injection site pain(31%), erythema (23%), irritability (18%),
induration (16%), sleepiness (14%), malaise (12%), and
headache (11%)
Ages 11-55
Injection site pain (41%), headache (30%), myalgia (18%),
malaise (16%) and nausea (10%)
These adverse reactions when compared to Menactra
were not significantly different.
10. Menveo®-pregnancy
● Pregnancy Category B – Animal Studies performed in females rabbits at a dose 20x
the human dose revealed no evidence of impaired fertility or harm to the fetus.
● Among 5065 adolescent and adult women enrolled:
– 43 were found to be pregnant during the 6-month follow-up period after
vaccination.
– 37 pregnancies occurred among 3952 Menveo® recipients
7 spontaneous abortions, no congenital anomalies
– 6 pregnancies occurred among 1113 Menactra® recipients
no spontaneous abortions, one congenital anomaly (hydrocephalus)
● Women who are pregnant or become aware that they are pregnant at the time of
Menveo injection should contact the Novartis Vaccines and Diagnostics Inc.
pregnancy registry at 1-877-311-8972
11. Menveo® vs Menactra®
Menveo® Menactra®
Pathogen N. meningitidis N. meningitidis
Serotypes A, C, Y, W-135 A, C, Y, W-135
Age 2-55 y/o 9 months – 55 y/o
Cost 5 pack-single dose vials:
$110.72
5 pack-single dose vials:
$112.72
Bottom Line:
●Menveo is non inferior to Menactra in the prevention of serogroups A, C, Y, W-135
caused by N. meningitidis. At this moment, based on cost and its age of approval, I
would not recommend it for the addition to the formulary. More studies on its long-
term safety profile would be beneficial for re-evaluation.
12. Menveo® vs. Menomune®
Menveo® Menomune®
Pathogen N. meningitidis N. meningitidis
Serotypes A, C, Y, W-135 A, C, Y, W-135
Age 2-55 y/o ≥2 y/o
Cost 5 pack-single dose vials:
$110.72
5 pack-single dose vials:
$112.72
13. Menhibrix®
● Approved June 2012 for infants and children ages 6
weeks - 18 months, for prevention of invasive
disease caused by Neisseria meningitidis serogroups
C and Y and Haemophilus influenzae type b.
● Administered as four IM doses at 2, 4, 6 and 12
through 15 months of age. The first dose may be
given as early as 6 weeks of age. The fourth dose
may be given as late as 18 months of age.
14. New vaccines 2013
● Flublok® (influenza vaccine)
● Approved January 2013
● Trivalent influenza vaccine made using an insect virus (baculovirus) expression
system and recombinant DNA technology – does not use the influenza virus or eggs
in its production.
● Indication - active immunization against influenza virus subtypes A and type B
● Flublok® is approved for use in persons 18 through 49 years of age.
Flublok® package insert, 2013
15. Vaccine recommendation updates
Pneumoccocal Polysaccharide Vaccine
2012
● Individuals 65+ y/o vaccinated with PPSV23 before age 65 years and for whom at least 5 years has
passed since their previous dose should be vaccinated with PPSV.
2013
● Individuals who have received 2 doses of PPSV23 before age 65 years are recommended to receive
PPSV23 at age 65 years, as long as it has been 5 years since the most recent dose.
● Pneumococcal Conjugate Vaccine 13 (PCV13) vaccine – recommended for adults aged 19 years or
older with immunocompromising conditions including chronic renal failure, cerebrospinal fluid
leaks and cochlear implants.
● Individuals not previously vaccinated with PCV13 or PPSV23 should receive a single dose of PCV13
16. Vaccine recommendations updates
Pneumoccocal Polysaccharide Vaccine
Notes
- Individuals 65 years and older, individuals ages 2-64 with long term
health problems including: heart disease, lung disease, sickle cell disease,
diabetes, alcoholism, cirrhosis, leaks if CSF should get the vaccine.
● Individuals ages 2-64 with immunocopromising conditions e.g. kidney
failure, HIV, organ transplant should also be vaccinated.
● Individuals ages 2-64 who on long term steroids, oncology drugs should
also be vaccinated.
● Adults 19-64 years old who are either smokers or have a history of asthma
17. Vaccine recommendations updates
Influenza
2012
● Infants 6 months or older can receive trivalent inactivated vaccine (TIV).
● Health care professionals caring for persons in a protected environment should receive TIV.
● Health care professionals younger than 50 y/o may receive either the live attenuated
influenza vaccine or TIV as long as they do not have any contraindications.
2013
● The influenza vaccination footnote (footnote 2) will now use the acronym IIV for inactivate
influenza vaccine.
● The acronym TIV has been dropped for trivalent inactivated vaccine.
● 2013–14 influenza season – LAIV will be available only in a quadrivalent formulation; IIV may
be available in both trivalent and quadrivalent formulations.
Notes
- Pregnant women, children 6 months and older, health care personnel, persons living in a
nursing home, individuals with a weakened immune system or have a long term chronic
illness should be vaccinated.
18. Vaccine recommendations updates
Tetanus, Diptheria, Pertussis (Tdap)
2012
● Persons who are close contacts of infants younger than 12 months of age e.g.
parents, grandparents, and child care providers and who have not received Tdap
previously are recommended to receive the vaccine.
● ACIP recommends pregnant women to receive the vaccination preferentially after 20
weeks gestation.
● Other adults in close contacts of children younger than 12 months are also advised to
receive a one-time dose of Tdap vaccine.
2013
● Adults aged 65 years or older should receive the vaccine.
● Pregnant women are now recommended to receive the Tdap vaccine with each
pregnancy.
Notes
● Recommended as a booster to the DTaP vaccine in children 11-12 years old.
● Adults 19-64 years old should also receive one dose of Tdap and a booster Td
vaccine every 10 years.
19. Vaccine recommendation updates
Human Papillomavirus (HPV) vaccine
2012
● While the HPV vaccine is not recommended for health care
employees, they should receive the vaccine if they are in
the specified age group.
● Males 11-12 years or males 13-21 years requiring catch up
vaccination may receive the quadrivalent human
papillomavirus (HPV4) vaccine.
● Males aged 22 to 26 years may also be vaccinated with
HPV4 vaccine.
2013
● No changes
20. Vaccine recommendation updates
Human Papillomavirus (HPV) vaccine
Notes
Gardasil® is approved for:
- Females ages 9-26 to protect against cervical cancer
and to prevent genital warts
- Males ages 9 - 26 to prevent genital warts
Cervarix® is approved for:
- Females age 10 - 26 to help protect against cervical
cancer
21. Vaccine recommendations updates
Herpes Zoster vaccination
2012
● Although zoster vaccination is not specifically
recommended for health care employees, they should
receive the vaccine if they are in the recommended age
group.
● The Herpes Zoster vaccine is FDA-approved for use in
persons aged 50 years or older – however ACIP continues
to recommend that vaccination begin at age 60 years.
2013
● Persons ≥ 60 years with or without underlying health
conditions are recommended to receive the Zoster vaccine.
22. Vaccine recommendations updates
Mumps, Measles, Rubella (MMR) Vaccine
2013
● A health care provider diagnosis of measles, mumps, or rubella is not considered
acceptable evidence of immunity.
● Previously, a provider diagnosis of measles or mumps but not rubella was considered
acceptable evidence of immunity.
Notes
- Children 12-15 months should get the vaccine and a second shot should be
administered when the child is 4-6 years old
- Adults born after 1956 should be vaccinated
23. Vaccine recommendations updates
Hepatitis A and B
2012
● Hepatitis B vaccination is now recommended for
individuals with diabetes who are ≤60 years or if
over 60 and requires glucose monitoring.
2013
● The hepatitis A vaccination is now recommended
for persons with a history of either injection or
non-injection illicit drug use.
24. Vaccine recommendations updates
Hepatitis A
Notes
- Recommended for all children 1 year and older, people travelling to Asia, Africa,
South America and the Caribbean
- Also recommended for individuals at higher risk including IV drug users, persons
with chronic liver disease, men who have sex with other men, employees of child
daycare centers, persons living in long term care facilities
- If you have had hepatitis A in the past this vaccination is not required.
Hepatitis B
Notes
- High risk individuals including health care workers, persons on dialysis, people
25. Vaccines in pregnancy
Recommended
Influenza (Inactivated), Tdap
Contraindicated
Influenza (LAIV), MMR, Varicella, Zoster
● Hepatitis B may be recommended in some circumstances: HIV
risk, treatment for STD, recent or current injection drug use
● Meningococcal and Pneumococcal lack sufficient data for
recommendation during pregnancy
26. References
1. Novartis Vaccines and Diagnostics, Inc. Menveo® package insert. Cambridge, MA:
2011, January
2. Anon. CDC Vaccine Price List. (http://www.cdc.
gov/vaccines/programs/vfc/awardees/vaccine-management/price-list/index.
html) . Updated 7 March 2013. Accessed 19 March 2013.
3. GlaxoSmithKline Biologicals, Inc. Menhibrix® package insert. Pixensart, Belgium:
2012
4. Anon. Recommended Adult Immunization Schedule: United States, 2012*. Ann
Intern Med. 2012 Feb;156(3):211-217.
5. Anon. Recommended Adult Immunization Schedule: United States, 2013* . Ann.
Internal Med. 2013 Feb;158(3):191-199.
6. Anon. Guidelines for Vaccinating Pregnant Women. (http://www.cdc.
gov/vaccines/pubs/preg-guide.htm#hepa) Updated March 2013. Accessed 19
March 2013.
7. Anon. Protein Science Corp. Flublok® package insert. Meriden, CT:2013, January