Cauda Equina Syndrome
• Spine Conference
• Tuesday Sepember 24, 2019
39 year old woman
Cc: B sciatica perineal
anesthesia
HPI: 2 weeks of symptoms
(June 2017), she thought it
was MS
PMH: bipolar, gastic sleeve
120/40 2014,
SH: disability, lives alone
Exam: 5/5 ankle DF/PF
L3L4
L4L5
L5S1
Note the R S1 nerve root
Typical L5S1 disc herniation
cauda equina
Cauda Equina Syndrome
Pain
saddle anesthesia
sacral nerve root
dysfunction
Is DRE valid?
Spine 2015 Vol 40 No 15 p 1213
75 doctors, 30 control medical assistants
Score 0-5 where 0=20mm Hg and 5= 130mm
Normal is 60 and decreased is 30mm
Anorectal manometry reveals range
Squeeze test is 180mm, more accurate
64% correct
Orthopedics March 2012 Vol 34,
No 3, page e414
LexisNexis academic legal search
data base; 104 lawsuits found 15
qualified
6/15 in favor of plaintiff with mean
award $1.6M ($230k- $7.5M)
27% involved initial presentation
of loss of B/B control; 60%
presented to ER
time to surgery>48 hours a/w
plaintiff award 83%
14/15 cases had no rectal exam
Bladder/Urination symptoms
Lack of bladder fullness sensation
Urinary retention
Urination down thigh in women
Overflow incontinence
Sexual dysfunction:
• Men: decreased sensation, EF
• Women: decreased sensation,
urinary incontinence during
intercourse
• Worse with increased age
Spine 2000 June 15; 25(12):1515-22
meta-analysis
322 patients
chronic LBP worse B/B
bowel dysfunction worse urinary
older age worse sex function
<24 hours no better than 24-48 hours
all patients have same outcome >48 hours
significant difference in B/B function and
sensation for patients <48 hours and >48
hours
Sacral nerve
root
resections
• (bowel/bladder loss)
• B S2S5 100%
• Unilateral preservation of S3
33%/40%
• Bilateral S2 preservation
60%/75%
• Bilateral S2S3
preservation 0%/30%
Nicholas Vyner Todd, UK neurosurgeon,
Newcastly upon Tyne, UK
Categories:
1. Suspicious
2. Incomplete
3. Retention (urinary)
4. Complete
Br J Neurosurgery 2016 review article
158 papers
<24 hours surgery 89% normal bladder
<48 hours surgery 79% normal bladder
>48 hours surgery 44% normal bladder
Emergency MRI critical for suspicious patients
B sciatica is suspicious
Incomplete bladder dysfunction patients are
true emergencies
“out of hours” surgery carry increased
morbidity and mortality
Shanghai, china
E: Early: B symptoms lower extremity m/s
I: incomplete
R: retention
BLE pain
BLE
paresthesia
B motor LE
B sciatica
Perineal
paresethsia
Perineal pain
Reduction
bladder
Reduction
bowel
Bladder
dysfuction
Bowel
dysfunction
222 cases
2000-2014 national database using icdm/cpt
codes for CES for disc, stenosis, tumor, hematoma
20k patients
Early <48 hours Late>48 hours
Routine d/c 48% 27%
Skilled facility 38% 57%
Mortality 0.18% 1.7%
Complications 20% 27%
Foley 1.8% 2.7%
Length of stay 6 days 9 days
Charges $71k $131k
Problem: physical exam is poor predictor for CES
Pre and postvoid bladder scan in predicting CES
6 months prospective, Nottingham UK; Spine 2019;44:1303
92 patients suspect CES, 18% nerve compression by MRI
53% sensitivity of anal tone to predict CES
82% sensitivity perianal numbness;92% negative predictive
value
PVR<200cc negative predictive value 98%, specificity 72% a d
sensitivity 94%
Thanks
Br J Neurosurgery 2017 Vol 31 no 3 p336
red flag is danger ahead, white flag is too late
Spine Lecture cauda equina syndrome 2019 sept

Spine Lecture cauda equina syndrome 2019 sept

  • 1.
    Cauda Equina Syndrome •Spine Conference • Tuesday Sepember 24, 2019
  • 2.
    39 year oldwoman Cc: B sciatica perineal anesthesia HPI: 2 weeks of symptoms (June 2017), she thought it was MS PMH: bipolar, gastic sleeve 120/40 2014, SH: disability, lives alone Exam: 5/5 ankle DF/PF
  • 4.
  • 5.
  • 6.
    Note the RS1 nerve root
  • 7.
  • 9.
  • 10.
  • 11.
  • 17.
    Is DRE valid? Spine2015 Vol 40 No 15 p 1213 75 doctors, 30 control medical assistants Score 0-5 where 0=20mm Hg and 5= 130mm Normal is 60 and decreased is 30mm Anorectal manometry reveals range Squeeze test is 180mm, more accurate 64% correct
  • 18.
    Orthopedics March 2012Vol 34, No 3, page e414 LexisNexis academic legal search data base; 104 lawsuits found 15 qualified 6/15 in favor of plaintiff with mean award $1.6M ($230k- $7.5M) 27% involved initial presentation of loss of B/B control; 60% presented to ER time to surgery>48 hours a/w plaintiff award 83% 14/15 cases had no rectal exam
  • 19.
    Bladder/Urination symptoms Lack ofbladder fullness sensation Urinary retention Urination down thigh in women Overflow incontinence
  • 21.
    Sexual dysfunction: • Men:decreased sensation, EF • Women: decreased sensation, urinary incontinence during intercourse • Worse with increased age
  • 23.
    Spine 2000 June15; 25(12):1515-22 meta-analysis 322 patients chronic LBP worse B/B bowel dysfunction worse urinary older age worse sex function <24 hours no better than 24-48 hours all patients have same outcome >48 hours significant difference in B/B function and sensation for patients <48 hours and >48 hours
  • 27.
    Sacral nerve root resections • (bowel/bladderloss) • B S2S5 100% • Unilateral preservation of S3 33%/40% • Bilateral S2 preservation 60%/75% • Bilateral S2S3 preservation 0%/30%
  • 29.
    Nicholas Vyner Todd,UK neurosurgeon, Newcastly upon Tyne, UK Categories: 1. Suspicious 2. Incomplete 3. Retention (urinary) 4. Complete Br J Neurosurgery 2016 review article 158 papers <24 hours surgery 89% normal bladder <48 hours surgery 79% normal bladder >48 hours surgery 44% normal bladder Emergency MRI critical for suspicious patients B sciatica is suspicious Incomplete bladder dysfunction patients are true emergencies “out of hours” surgery carry increased morbidity and mortality
  • 31.
  • 32.
    E: Early: Bsymptoms lower extremity m/s I: incomplete R: retention
  • 33.
    BLE pain BLE paresthesia B motorLE B sciatica Perineal paresethsia Perineal pain Reduction bladder Reduction bowel Bladder dysfuction Bowel dysfunction 222 cases
  • 34.
    2000-2014 national databaseusing icdm/cpt codes for CES for disc, stenosis, tumor, hematoma 20k patients Early <48 hours Late>48 hours Routine d/c 48% 27% Skilled facility 38% 57% Mortality 0.18% 1.7% Complications 20% 27% Foley 1.8% 2.7% Length of stay 6 days 9 days Charges $71k $131k
  • 35.
    Problem: physical examis poor predictor for CES Pre and postvoid bladder scan in predicting CES 6 months prospective, Nottingham UK; Spine 2019;44:1303 92 patients suspect CES, 18% nerve compression by MRI 53% sensitivity of anal tone to predict CES 82% sensitivity perianal numbness;92% negative predictive value PVR<200cc negative predictive value 98%, specificity 72% a d sensitivity 94%
  • 36.
  • 43.
    Br J Neurosurgery2017 Vol 31 no 3 p336 red flag is danger ahead, white flag is too late