The document discusses sleep apnea, defining it as a potentially serious sleep disorder where breathing stops and starts repeatedly. It describes the main types as obstructive, central, and complex sleep apnea. Risk factors include being overweight, having a recessed chin, enlarged tonsils, or a thick neck. Signs include loud snoring, witnessed breathing pauses, and daytime sleepiness. Diagnosis involves physical exams and polysomnography. Treatment options presented are lifestyle changes, continuous positive airway pressure devices, dental devices, and surgery.
Types of sleep apnea exist, and your physician diagnoses the specific type you have. The most common types are obstructive sleep apnea (OSA) and central sleep apnea (CSA). While not actually a separate category, mixed sleep apnea (MSA), which shows characteristics of both OSA and CSA at different times during sleep, is also diagnosed.
There are many tests used to provide a diagnosis for OSA, depending on whether you go to a pulmonologist or an otolaryngologist/head & neck surgeon. But all initial diagnostic procedures are designed to determine if your airway becomes blocked while you are asleep. If so, this will cause your brain to "wake up" several times throughout the night, generally resulting in loud snoring, pauses of breathing (apnea), and more frequent awakenings.
1. Sleep Apnea Prepared by: dr. Mohamad Ghazi 1
2. Outline: • Sleep Apnea definition • Epidemiology • Types of Sleep Apnea • Risk factors for Obstructive sleep apnea • Diagnosis • OSA can increase the risk of ? • Treatment Options for Sleep Apnea • Conclusion 2
3. Sleep Apnea is defined as the stopping of airflow during sleep and preventing air from entering the lungs caused by an obstruction.(1) What is Sleep Apnea? 1.British Snoring & Sleep Apnoea Association . 2. Orthodontics - Current Principles and Techniques - Graber 5th edition - 2011 Just as allergic disease significantly affects quality of life, obstructive sleep apnea, if it is untreated, may affect adversely the ability of adults and children to function adequately at work and at school.(2) 3
4. 4
5. Is Sleep Apnea Significant Health Issue ? 22 million Americans suffer from sleep apnea, with 80 percent of the cases of moderate and severe obstructive sleep apnea undiagnosed. (3) 3.American Sleep Apnea Association 4.Young et al 1993 5.Young et al 2002 15. Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics. 2012; 130: 576-84. EPIDEMIOLOGY: OSA present in 25-58% of Male and 10-37% of Female. (4)(5) According to a report by American Academy of Pediatrics, depends on the population studied, the prevalence of OSAS is in the range of 1% to 5% (15) 5
6. Types of Sleep Apnea: Obstructive sleep apnea is the most common type of sleep apnea. It occurs when the soft tissue in the back of your throat relaxes during sleep and blocks the airway, often causing you to snore loudly. 6
7. Central sleep apnea is a much less common type of sleep apnea that involves the central nervous system, occurring when the brain fails to signal the muscles that control breathing. People with central sleep apnea seldom snore. Complex sleep apnea is a combination of obstructive sleep apnea and central sleep apnea. A) Obstructive sleep apnea. Note continued chest and abdominal effort in the absence of airflow. B) Central sleep apnea. Note absence of chest and abdominal effort, as well as absence of airflow 7
8. You have a higher risk for obstructive sleep apnea if you are: Overweight ??? (Most Important Factor) 5.Young et al 2002 6.National Institutes of Health 14.Malhotra et al 2002 • About 70% of those with OSA are obese (14) • Higher BMI associated with higher prevalence – BMI>30: 26% with AHI>15, 60% with AHI>5 – BMI>40: 33% with AHI>15, 98% with AHI>5 Obese people have extrinsic narrowing of the area surrounding collapsible region of the pharynx and regional soft tissue enlargement. Increased fat deposits posteriolateral to oropharyngeal airspace at level of soft palate, in the soft palate, and in submental area. Risk factors for Obstructive sleep apnea(6) 8
9. • Sex : Male are more likely than Female to have sleep apnea. • Age : the risk increases as you get older. • A family history of sleep apnea.
This presentation outlines sleep dentistry whiten the context of sleep medicine. Dr John Viviano DDS prepared this presentation to educate and encourage local dentists interested in the practice of Sleep Disorders Dentistry
Obstructive sleep apnea (osa)The relationship of airway obstruction and dento...奇卿 黃
Airway obstruction, coupled with loss of lingual and palatal pressure of the tongue, produces alterations in the maxilla. The positioning of the tongue also plays an important role in mandibular development. The tongue displaced downward can lead to a retrognathic mandible; and an interposed tongue can lead to anterior occlusal anomalies.
Types of sleep apnea exist, and your physician diagnoses the specific type you have. The most common types are obstructive sleep apnea (OSA) and central sleep apnea (CSA). While not actually a separate category, mixed sleep apnea (MSA), which shows characteristics of both OSA and CSA at different times during sleep, is also diagnosed.
There are many tests used to provide a diagnosis for OSA, depending on whether you go to a pulmonologist or an otolaryngologist/head & neck surgeon. But all initial diagnostic procedures are designed to determine if your airway becomes blocked while you are asleep. If so, this will cause your brain to "wake up" several times throughout the night, generally resulting in loud snoring, pauses of breathing (apnea), and more frequent awakenings.
1. Sleep Apnea Prepared by: dr. Mohamad Ghazi 1
2. Outline: • Sleep Apnea definition • Epidemiology • Types of Sleep Apnea • Risk factors for Obstructive sleep apnea • Diagnosis • OSA can increase the risk of ? • Treatment Options for Sleep Apnea • Conclusion 2
3. Sleep Apnea is defined as the stopping of airflow during sleep and preventing air from entering the lungs caused by an obstruction.(1) What is Sleep Apnea? 1.British Snoring & Sleep Apnoea Association . 2. Orthodontics - Current Principles and Techniques - Graber 5th edition - 2011 Just as allergic disease significantly affects quality of life, obstructive sleep apnea, if it is untreated, may affect adversely the ability of adults and children to function adequately at work and at school.(2) 3
4. 4
5. Is Sleep Apnea Significant Health Issue ? 22 million Americans suffer from sleep apnea, with 80 percent of the cases of moderate and severe obstructive sleep apnea undiagnosed. (3) 3.American Sleep Apnea Association 4.Young et al 1993 5.Young et al 2002 15. Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics. 2012; 130: 576-84. EPIDEMIOLOGY: OSA present in 25-58% of Male and 10-37% of Female. (4)(5) According to a report by American Academy of Pediatrics, depends on the population studied, the prevalence of OSAS is in the range of 1% to 5% (15) 5
6. Types of Sleep Apnea: Obstructive sleep apnea is the most common type of sleep apnea. It occurs when the soft tissue in the back of your throat relaxes during sleep and blocks the airway, often causing you to snore loudly. 6
7. Central sleep apnea is a much less common type of sleep apnea that involves the central nervous system, occurring when the brain fails to signal the muscles that control breathing. People with central sleep apnea seldom snore. Complex sleep apnea is a combination of obstructive sleep apnea and central sleep apnea. A) Obstructive sleep apnea. Note continued chest and abdominal effort in the absence of airflow. B) Central sleep apnea. Note absence of chest and abdominal effort, as well as absence of airflow 7
8. You have a higher risk for obstructive sleep apnea if you are: Overweight ??? (Most Important Factor) 5.Young et al 2002 6.National Institutes of Health 14.Malhotra et al 2002 • About 70% of those with OSA are obese (14) • Higher BMI associated with higher prevalence – BMI>30: 26% with AHI>15, 60% with AHI>5 – BMI>40: 33% with AHI>15, 98% with AHI>5 Obese people have extrinsic narrowing of the area surrounding collapsible region of the pharynx and regional soft tissue enlargement. Increased fat deposits posteriolateral to oropharyngeal airspace at level of soft palate, in the soft palate, and in submental area. Risk factors for Obstructive sleep apnea(6) 8
9. • Sex : Male are more likely than Female to have sleep apnea. • Age : the risk increases as you get older. • A family history of sleep apnea.
This presentation outlines sleep dentistry whiten the context of sleep medicine. Dr John Viviano DDS prepared this presentation to educate and encourage local dentists interested in the practice of Sleep Disorders Dentistry
Obstructive sleep apnea (osa)The relationship of airway obstruction and dento...奇卿 黃
Airway obstruction, coupled with loss of lingual and palatal pressure of the tongue, produces alterations in the maxilla. The positioning of the tongue also plays an important role in mandibular development. The tongue displaced downward can lead to a retrognathic mandible; and an interposed tongue can lead to anterior occlusal anomalies.
Obstructive sleep apnea /certified fixed orthodontic courses by Indian dental...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Obstructive sleep apnea /certified fixed orthodontic courses by Indian denta...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Obstructive sleep apnea (OSA) is a prevalent chronic disease characterized by pharyngeal collapse during sleep.
Sleep disorder that involves cessation or significant decrease in airflow through the upper airway in the presence of breathing effort.
Obstructive sleep apnea is the second most common sleep disorder, insomnia being the most common.
Associated with recurrent oxyhemoglobin desaturations and arousals from sleep
Apnea index- no. of apneas /hr of total sleep time.
AHI (APNEA-HYPOPNEA INDEX)- No of apneas and hypoapneas/hr of total sleep time.
RDI (Respiratory Disturbance Index) – no. of apneas, hypoapneas and respiratory effort related arousals(RERA)/hr of total sleep time.
http://tinyurl.com/bestsnoringremedy - Sleep Apnea Remedy
Sleep Apnea Definition, Risk Factors, Symptoms, Effects and Treatment
What is Sleep Apnea? Apnea is a sleep disorder characterized by abnormal pauses in breathing or instances of abnormally low breathing, during sleep can last from at ten seconds to minutes, and may occur 5 to 30 times or more an hour• diagnosed with an overnight sleep test called a polysomnogram, or "sleep study"
Risk Factors Male, overweight, over 40 years old• Having a large neck size (17 inches or greater in men and 16 inches or greater in women)• Family history of apnea• Gastroesophageal reflux, or GERD• Nasal obstruction due to a deviated septum, allergies, or sinus problems
4. Symptoms of Sleep Apnea• Loud snoring• Waking up with sore and/or dry throat• Occasionally waking up with a choking or gasping sensation• Restless sleep• Waking with headaches
5. Effects of Sleep Apnea• High blood pressure• Stroke• Heart failure• Diabetes• Depression• Cancer (New finding)
6. Treating Sleep Apnea• Losing weight• Avoid sleeping on back• Use a Continuous Positive Airway Pressure (CPAP)• Dental devices can keep airway open• Snoreless Pillow is the best option, cheapest and least disruptive to sleep
7. Best Sleep Apnea Treatment is the Snoreless Pillow
Obstructive sleep apnea or OSA is a potentially serious sleep disorder. It causes breathing to repeatedly stop and start during sleep.
There are several types of sleep apnea, but the most common is obstructive sleep apnea(OSA). This type of apnea occurs when your throat muscles intermittently relax and block your airway during sleep. A noticeable sign of obstructive sleep apnea is snoring.
Treatments for obstructive sleep apnea are available. One treatment involves using a device that uses positive pressure to keep your airway open while you sleep. Another option is a mouthpiece to thrust your lower jaw forward during sleep. In some cases, surgery may be an only option with Maxillilomandibular advancement(MMA) producing highest success rate of near 90%.
DR. PUNIT DUBEY
International Board Certified
Facial Plastic Surgeon
CranioMaxilloFacial and Cosmetic Surgeon
MDS(RGUHS,Bangalore), FIBCSOMS (USA)
New Delhi
+918123822284
www.thefacialplasticsurgery.com
Snoring and Obstructive Sleep Apnea:ManagementDr. Paulose
By Dr.K.O.Paulose FRCS DLO
Consultant ENT Surgeon, Jubilee Hospital, Trivandrum, South India.www.drpaulose.com
www.snorefreesleep.com
Presentation in Indian Medical Association meeting on 07102011, Trivandrum Chapter.
Obstructive sleep apnea /certified fixed orthodontic courses by Indian dental...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Obstructive sleep apnea /certified fixed orthodontic courses by Indian denta...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Obstructive sleep apnea (OSA) is a prevalent chronic disease characterized by pharyngeal collapse during sleep.
Sleep disorder that involves cessation or significant decrease in airflow through the upper airway in the presence of breathing effort.
Obstructive sleep apnea is the second most common sleep disorder, insomnia being the most common.
Associated with recurrent oxyhemoglobin desaturations and arousals from sleep
Apnea index- no. of apneas /hr of total sleep time.
AHI (APNEA-HYPOPNEA INDEX)- No of apneas and hypoapneas/hr of total sleep time.
RDI (Respiratory Disturbance Index) – no. of apneas, hypoapneas and respiratory effort related arousals(RERA)/hr of total sleep time.
http://tinyurl.com/bestsnoringremedy - Sleep Apnea Remedy
Sleep Apnea Definition, Risk Factors, Symptoms, Effects and Treatment
What is Sleep Apnea? Apnea is a sleep disorder characterized by abnormal pauses in breathing or instances of abnormally low breathing, during sleep can last from at ten seconds to minutes, and may occur 5 to 30 times or more an hour• diagnosed with an overnight sleep test called a polysomnogram, or "sleep study"
Risk Factors Male, overweight, over 40 years old• Having a large neck size (17 inches or greater in men and 16 inches or greater in women)• Family history of apnea• Gastroesophageal reflux, or GERD• Nasal obstruction due to a deviated septum, allergies, or sinus problems
4. Symptoms of Sleep Apnea• Loud snoring• Waking up with sore and/or dry throat• Occasionally waking up with a choking or gasping sensation• Restless sleep• Waking with headaches
5. Effects of Sleep Apnea• High blood pressure• Stroke• Heart failure• Diabetes• Depression• Cancer (New finding)
6. Treating Sleep Apnea• Losing weight• Avoid sleeping on back• Use a Continuous Positive Airway Pressure (CPAP)• Dental devices can keep airway open• Snoreless Pillow is the best option, cheapest and least disruptive to sleep
7. Best Sleep Apnea Treatment is the Snoreless Pillow
Obstructive sleep apnea or OSA is a potentially serious sleep disorder. It causes breathing to repeatedly stop and start during sleep.
There are several types of sleep apnea, but the most common is obstructive sleep apnea(OSA). This type of apnea occurs when your throat muscles intermittently relax and block your airway during sleep. A noticeable sign of obstructive sleep apnea is snoring.
Treatments for obstructive sleep apnea are available. One treatment involves using a device that uses positive pressure to keep your airway open while you sleep. Another option is a mouthpiece to thrust your lower jaw forward during sleep. In some cases, surgery may be an only option with Maxillilomandibular advancement(MMA) producing highest success rate of near 90%.
DR. PUNIT DUBEY
International Board Certified
Facial Plastic Surgeon
CranioMaxilloFacial and Cosmetic Surgeon
MDS(RGUHS,Bangalore), FIBCSOMS (USA)
New Delhi
+918123822284
www.thefacialplasticsurgery.com
Snoring and Obstructive Sleep Apnea:ManagementDr. Paulose
By Dr.K.O.Paulose FRCS DLO
Consultant ENT Surgeon, Jubilee Hospital, Trivandrum, South India.www.drpaulose.com
www.snorefreesleep.com
Presentation in Indian Medical Association meeting on 07102011, Trivandrum Chapter.
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
What are the different types of sleep apnea.pptxleelindesy
In this type of sleep apnea, the obstruction in the mouth and nose becomes the cause for hindered breathing. So, inhaling and exhaling becomes difficult when your tongue falls against the soft palate, or the uvula falls against the throat.
Often dismissed as a habit, mouth breathing is a health problem due to the presence of nasal obstruction. An experienced ear nose and throat surgeon can help solve this problem for you or your child.
Obstructive Sleep Apnea a type of sleep disorderGunalan M.M
OSA, or Obstructive Sleep Apnea, is a sleep disorder characterized by repeated interruptions in breathing during sleep due to blocked or narrowed airways. This obstruction can lead to fragmented sleep, daytime fatigue, and other health complications if left untreated. Treatment options include lifestyle changes, CPAP therapy, and in some cases, surgery.
VirtuOx Medicare Approved IDTF is the nation’s leader in Home Sleep Testing and Overnight Oximetry. VirtuOx Sells Overnight Oximeters, Oximeter Probes and Patient Monitors. For more information please visit https://www.virtuox.net/Services/HomeSleepTesting
VirtuOx Medicare Approved IDTF is the nation’s leader in Home Sleep Testing and Overnight Oximetry. VirtuOx Sells Overnight Oximeters, Oximeter Probes and Patient Monitors. For more information please visit https://www.virtuox.net/Services/HomeSleepTesting
Analysis on parameters affecting sleep apnea & control measures using low...eSAT Journals
Abstract Sleep apnea is a potentially serious sleep disorder in which breathing repeatedly stops and starts for at least ten seconds. Apnea may occur 5 to 30 times or more in patients during sleep. Sleep apnea is diagnosed with an overnight sleep test called a polysomnogram, or "sleep study". More than eighteen million Americans suffer from sleep apnea (ASAA), and it is estimated conservatively that ten million remain undiagnosed. There are many ways to control sleep apnea i.e., through respiratory devices (CPAP, Bi-PAP), surgery on mouth and throat, Oral Appliance Therapy (OAT) etc. These respiratory devices are not self controlled which disturbs the patients sleep and should be turn ON throughout the night continuously In this Research, the objective is to develop a Bi-PAP device (Automatic Bi-level Positive Airway Pressure machine) for the purpose of detection and controlling of sleep apnea disease using Atmel 89c51 Microcontroller programming. Here, a new methodology is followed to detect the sleep apnea condition in a patient by using active Infrared source and Infrared detector. The program is specifically to control the functioning of the Bi-PAP and is shown to be effective at responding to a patient’s breathing cycle. Central sleep apnea can also be detected and alarmed such that this ability could prove critic during emergency situations. In particular, the current Bi-PAP machine operates depending up on the patient’s necessity for positive air pressure. Therefore the BiPAP acting time on a patient can be reduced and hence, BiPAP side effects can be minimized. A Humidifier is also engaged along with saturated oxygen line to clear patients’ airway. Based on the results, the Automatic BiPAP system is shown to be more effective at responding sleep apnea condition by giving alarm signal. It is economically good and maintenance free. Exclusively, in this system Apneas both in infants and adults are detected by the adjustable sensing time. Current design acts positively on demerits of existing methodologies. The system has been validated on a single live subject in the Sleep Research Laboratory. Finally, it is found that this fully functional Bi-PAP is compatible for both home & hospital usage. Development of this device in several aspects will be a great achievement.
Analysis on parameters affecting sleep apnea & control measures using low cos...eSAT Publishing House
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?
Sleep apnea
1. UNIVERSIDAD TECNICA DE MACHALA
ACADEMIC UNIT OF CHEMICAL
SCIENCES AND HEALTH
MEDICINE SCHOOL
ENGLISH
SLEEP APNEA
STUDENTS
William Cruz
Kevin Herrera
Jorge Pacheco
Angie Chamba
Sonia Quijilema
TEACHER:
Mgs. Barreto Huilcapi Lina Maribel
CLASS:
EIGHTH SEMESTER ‘’A’’
Machala, El Oro
2018
2. Sleep Apnea
Definition
Sleep apnea is a potentially serious sleep disorder, in which breathing stops and starts again
and again. You may suffer from sleep apnea if you snore loudly and you feel tired even
after a full night of sleep.
The main types of sleep apnea are the following:
Obstructive sleep apnea, the most common form, which occurs when the muscles of
the throat relax.
Central sleep apnea, which occurs when the brain does not send correct signals to
the muscles that control breathing.
Complex sleep apnea syndrome, also called "central apnea of emergent sleep",
which occurs when someone suffers from obstructive sleep apnea and central sleep
apnea.
3. Etiology
When you sleep, all the muscles of the body relax more. This includes the muscles that help
keep the throat open so that air can flow into the lungs.
Normally, the throat remains sufficiently open during sleep to allow air passage. Some
people have a narrower throat. When the muscles in the upper part of the throat relax
during sleep, the tissues close and block the airway. This arrest of breathing is called apnea.
Harsh snoring is a warning sign of AOS. Snoring is caused by air that drains through the
narrowed or blocked airway. Although not all people who snore suffer from sleep apnea.
Other factors can also increase the risk:
A lower jaw that is short compared to the maxilla
Certain forms of the roof of the mouth (palate) or the airway that cause the latter to
collapse more easily
Neck or large collar, 17 inches (43 cm) or more in men and 16 inches (41 cm) or
more in women
Large tongue that can retract and block the airway
Obesity
Tonsils and large adenoids that can block the airway
Signs and symptoms
The signs and symptoms of obstructive sleep apnea and central sleep apnea coincide,
making it more difficult to determine the type of apnea. Some of the most frequent signs
and symptoms of obstructive sleep apnea and central sleep apnea are:
Strong snoring, which is usually more prominent in obstructive sleep apnea
Episodes of cessation of breathing during sleep that is witnessed by another person
Abrupt awakenings accompanied by shortness of breath, which probably indicates
central sleep apnea
Waking up with a dry mouth or sore throat
Headache in the morning
Difficulty to stay asleep (insomnia)
Excessive daytime sleepiness (hypersomnia)
Attention problems
4. Irritability
Diagnosis
The physical examination is:
It will check your mouth, neck and throat.
You may be asked about daytime sleepiness, sleep quality, and bedtime habits.
You may need a polysomnogram to confirm OSA. This test can be done at home or
in a sleep laboratory.
Other tests that may be carried out include:
Arterial blood gases
Electrocardiography (ECG)
Echocardiography
Studies of thyroid function
Treatment
The treatment helps keep the airway open while you sleep so that your breathing does not
stop.
Lifestyle changes can relieve symptoms in people with mild sleep apnea, such as:
Avoid alcohol or sleeping pills before bedtime (may worsen symptoms)
Avoid sleeping on your back
Lose excess weight
Continuous positive airway pressure (CPAP) devices work best for the treatment of
obstructive sleep apnea in most people.
You put a mask on your nose or on your nose and mouth while you sleep.
The mask is connected by means of a hose to a small machine that stays next to your bed.
The machine pumps air under pressure through the hose and the mask into the airways
while you sleep. This helps keep the airway open.
It may take some time to get used to sleeping with CPAP therapy. Good control and
support of a sleep center can help overcome any problem in the use of CPAP.
Dental devices can help some people. You put them in your mouth while you sleep to keep
the jaw forward and the airway open.
5. Other treatments may be available, but there is little evidence that they work. It is best to
talk to a doctor who specializes in sleep problems before trying them.
Surgery may be an option for some people. It is often a last resort if other treatments did
not work and you have severe symptoms. The surgery can be used to:
Remove extra tissue in the back of the throat.
Correct problems of the structures of the face.
Create an opening in the trachea to bypass blocked airways if there are physical
problems.
Remove the tonsils and adenoids.
Surgery may not completely cure obstructive sleep apnea and may have long-term
side effects.
Prevention
The prevention of sleep apnea is not always possible, although the different measures of
lifestyle changes can help: avoid alcohol, do not take sleeping pills, lose weight and avoid
obesity.
Bibliography
American Academy of Sleep Medicine. International classification of sleep
disorders. Diagnostic and coding manual. 2nd ed. Westchester, Illinois: American
Academy of Sleep Medicine, 2005: 51.
Iber C, Ancoli-Israel S, Chesson A, Quan SF for the American Academy of Sleep
Medicine. The AASM manual for the scoring of sleep and associated events: rules,
terminology and technical specifications. Westchester, Illinois: American Academy
of Sleep Medicine; 2007
Ohayon MM, Guilleminault C, Priest RG, Caulet M. Snoring and breathing pauses
during sleep: telephone interview surrey of a United Kingdom population sample.
BMJ 1997; 314: 860-863