The study evaluated outcomes of 1257 off-pump coronary artery bypass (OPCAB) cases from 2001-2009. Patients who developed atrial fibrillation (AF) post-operatively had higher rates of prior PCI, congestive heart failure, age over 70, and pneumonia. Multivariate analysis identified prior PCI, pneumonia, congestive heart failure, and age over 70 as independent risk factors for longer hospital stays and higher 30-day mortality following OPCAB.