Rotational atherectomy can be performed via the radial or femoral artery approaches with similar success rates. A study compared outcomes of 67 patients who underwent rotational atherectomy via the femoral approach to 52 patients who underwent it via the radial approach and found no significant differences in procedural characteristics, success rates, or in-hospital complications between the two groups except that pacing wires were inserted less often in the radial group. Overall, rotational atherectomy performed via the radial approach was found to be a feasible alternative to the femoral approach.
Impact of access site on bleeding and ischemic events in patients with non-ST-segment elevation myocardial infarction treated with prasugrel at the time of percutaneous coronary intervention or as pretreatment at the time of diagnosis: the ACCOAST access substudy
Impact of access site on bleeding and ischemic events in patients with non-ST-segment elevation myocardial infarction treated with prasugrel at the time of percutaneous coronary intervention or as pretreatment at the time of diagnosis: the ACCOAST access substudy
Emmanouil S. Brilakis - CTO PCI Outcome associated with poor quality of the d...Euro CTO Club
16:53
CTO PCI Outcome associated with poor quality of the distal target vessel
Emmanouil Brilakis (Minneapolis - USA)
_____________________________________________
PARALLEL SESSION
Interventional CTO & Chip Research
Best CTO Publications 2022-23 (selected by the Editors of the Cardiology Interventional journals)
Auditorium Zubin Mehta - Friday 16:30 - 17:16
Chairpersons:
Davide Capodanno (Catania),
Carlo Di Mario (Florence),
Giuseppe Tarantini (Padua)
Panelist:
Roberto Diletti (Rotterdam - NL),
Giovanni Esposito (Naples),
Paul Knaapen (Amsterdam - NL),
Maksymilian Opolski (Warsaw - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Phone Us ❤85270-49040❤ #ℂall #gIRLS In Surat By Surat @ℂall @Girls Hotel With...
Dzavik V - AIMRADIAL 2014 - Rotablator and radial approach
1. Peter Munk Cardiac Centre
University Health Network
Rotation Atherectomy
and
Radial vs. Femoral Approach
Vladimír Džavík MD
Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada
AIM-RADIAL, Chicago, October 23, 2014
8. Peter Munk Cardiac Centre
University Health Network
After stenting – 2 DES
9. from New Jersey
Peter Munk Cardiac Centre
University Health Network
10. Peter Munk Cardiac Centre
University Health Network
Baseline Characteristics
Gioia et al. Catheter and Cardiovasc Intervent 2000;51:234–238
11. Peter Munk Cardiac Centre
University Health Network
Angiographic and Procedural
Characteristics
3 patients discharged same day, 10 next day, 3 on Day 2
17. Peter Munk Cardiac Centre
University Health Network
Baseline Characteristics
Kassimis et al. EuroIntervention 2014;10:694-699
18. Peter Munk Cardiac Centre
University Health Network
Procedural Characteristics
Kassimis et al. EuroIntervention 2014;10:694-699
19. Peter Munk Cardiac Centre
University Health Network
In-hospital Outcomes
Kassimis et al. EuroIntervention 2014;10:694-699
20. Rotational atherectomy via the radial artery
Peter Munk Cardiac Centre
University Health Network
is associated with similar procedural
success when compared to the
transfemoral route
Mark A. Kotowycz, Sohail Q. Khan, Xavier Freixa, Joan Ivanov, Peter H. Seidelin,
Christopher B. Overgaard, Vladimír Džavík
Interventional Cardiology Program
Peter Munk Cardiac Centre, University Health Network
Toronto, Ontario, Canada
Coronary Artery Disease (in press)
21. Peter Munk Cardiac Centre
University Health Network
Baseline Characteristics
Variable Femoral
n = 67
Radial
n = 52
P value
Age (years) 71.3 ± 10.5 71.0 ± 10.2 0.89
Male 43 (64) 43 (83) 0.03
Smoking (current or
former)
31 (46) 35 (67) 0.02
Hypertension 58 (87) 41 (79) 0.26
Dyslipidemia 58 (87) 44 (85) 0.76
Diabetes 33 (49) 15 (29) 0.02
Prior MI 25 (37) 12 (23) 0.10
Prior PCI 27 (40) 21 (40) 0.86
Prior CABG 11 (16) 9 (17) 0.93
Prior CVA 3 (4) 3 (6) 0.75
Presentation:
Elective 39 (58) 39 (75)
Urgent
(ACS/NSTEMI)
27 (40) 11 (21)
Acute MI (STEMI) 1 (1) 2 (4)
CCS Class 3 or 4 41 (61) 27 (52) 0.31
Kotowycz et al. Coronary Artery Disease (in press)
22. Peter Munk Cardiac Centre
University Health Network
Procedural Characteristics
Variable Femoral
group
n = 67
Radial
group
n = 52
P value
Target Vessel:
Left Main 3 (4) 1 (2) 0.63
LAD 31 (46) 17 (33) 0.13
LCx 6 (9) 11 (21) 0.06
RCA 27 (40) 23 (44) 0.67
ACC/AHA Lesion Type:
A/B1 1 (1) 0 (0)
B2 12 (18) 17 (33)
C 54 (81) 35 (67)
Ad Hoc PCI 7 (10) 6 (12) 0.85
Ad Hoc Rotablation 32 (48) 34 (65) 0.06
Kotowycz et al. Coronary Artery Disease (in press)
23. Peter Munk Cardiac Centre
University Health Network
Procedural Variables
Variable Femoral group
n = 67
Radial group
n = 52
P value
Access site crossover 0 (0) 3 (6) 0.08
Guiding Catheter Size:
6-French 20 (30) 36 (69)
7-French 41 (62) 16 (31)
8-French 6 (9) 0 (0)
Average 6.79 ± 0.59 6.31 ± 0.47 < 0.001
Number of Burrs:
1 39 (58) 26 (50)
2 26 (39) 24 (46)
3 2 (3) 2 (4)
Average Burr Size:
Burr 1 1.34 ± 0.14 1.34 ± 0.13 0.74
Burr 2 1.63 ± 0.16 1.62 ± 0.15 0.82
Burr 3 1.88 ± 0.18 1.75 ± 0 0.42
Kotowycz et al. Coronary Artery Disease (in press)
24. Peter Munk Cardiac Centre
University Health Network
Procedural variables
Variable Femoral group
n = 67
Radial group
n = 52
P value
Successful Rotablation 61 (91) 50 (96) 0.46
Average number of stents 1.66 ± 1.20 1.79 ± 1.54 0.60
Average stent diameter (mm) 2.97 ± 0.48 3.02 ± 0.47 0.60
Stent length (mm) 40.3 ± 27.9 34.2 ± 27.3 0.25
Use of drug-eluting stent (%) 27 (40) 20 (38) 0.71
Use of GP IIb/IIIa Inhibitor (%) 35 (52) 28 (54) 0.86
Insertion of pacing wire (%) 17 (25) 3 (6) 0.0057
Insertion of IABP (%) 6 (9) 1 (2) 0.13
Fluoroscopy time (minutes) 40.5 ± 21.2 43.8 ± 18.1 0.37
Radiation exposure (cGy cm2) 27743 ± 16541 29939 ± 15192 0.50
Contrast used (mL) 429 ± 182 384 ± 189 0.19
Kotowycz et al. Coronary Artery Disease (in press)
25. Peter Munk Cardiac Centre
University Health Network
In-hospital Outcomes
Complication Femoral
n = 67
Radial
n = 52
P value
Death 3 (4.5) 1 (1.9) 0.63
Peri-procedural MI (CK > 2 ULN) 6 (9.0) 3 (5.8) 0.73
Urgent CABG 1 (1.5 ) 0 (0) 1.00
Blood transfusion 3 (4.5) 0 (0) 0.26
MACE (death, MI or urgent CABG) 10 (14.9) 4 (7.7) 0.26
MACE or blood transfusion 11 (16.4) 4 (7.7) 0.18
Kotowycz et al. Coronary Artery Disease (in press)
26. Peter Munk Cardiac Centre
University Health Network
Causes of Death
Patient age/sex Indication Access Burr size (mm) Cause of death
96/F ACS RF 1.25 Tamponade 2º to RA
75/F ACS RF 1.25 Stent thrombosis
76/M ACS LF 1.50 Palliative
88/F STEMI RR 1.50 Bleed
27. Peter Munk Cardiac Centre
University Health Network
A long, dominant LCx lesion
28. Peter Munk Cardiac Centre
University Health Network
Unable to advance a balloon
30. Peter Munk Cardiac Centre
University Health Network
IN SUMMARY
• Rotational Atherectomy via the transradial approach is
feasible and associated with results that similar to
those achieved utilizing the transfemoral approach
• Bleeding complications may be decreased