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Peter Munk Cardiac Centre 
University Health Network 
Rotation Atherectomy 
and 
Radial vs. Femoral Approach 
Vladimír Džavík MD 
Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada 
AIM-RADIAL, Chicago, October 23, 2014
Peter Munk Cardiac Centre 
University Health Network 
A recanalized RCA?
Peter Munk Cardiac Centre 
University Health Network 
RAO view
Peter Munk Cardiac Centre 
University Health Network 
After wiring
Peter Munk Cardiac Centre 
University Health Network 
Rotawire floppy and a 1.5 mm burr
Peter Munk Cardiac Centre 
University Health Network 
Predilation achieved easily
Peter Munk Cardiac Centre 
University Health Network 
After predilation
Peter Munk Cardiac Centre 
University Health Network 
After stenting – 2 DES
from New Jersey 
Peter Munk Cardiac Centre 
University Health Network
Peter Munk Cardiac Centre 
University Health Network 
Baseline Characteristics 
Gioia et al. Catheter and Cardiovasc Intervent 2000;51:234–238
Peter Munk Cardiac Centre 
University Health Network 
Angiographic and Procedural 
Characteristics 
3 patients discharged same day, 10 next day, 3 on Day 2
Peter Munk Cardiac Centre 
University Health Network
Peter Munk Cardiac Centre 
University Health Network 
Baseline Characteristics 
Watt & Oldroyd Catheter Cardiovasc Intervent 2009;74:550–554
Peter Munk Cardiac Centre 
University Health Network 
Procedural Characteristics 
Watt & Oldroyd Catheter Cardiovasc Intervent 2009;74:550–554
Peter Munk Cardiac Centre 
University Health Network 
In-hospital outcomes 
Watt & Oldroyd Catheter Cardiovasc Intervent 2009;74:550–554
Peter Munk Cardiac Centre 
University Health Network
Peter Munk Cardiac Centre 
University Health Network 
Baseline Characteristics 
Kassimis et al. EuroIntervention 2014;10:694-699
Peter Munk Cardiac Centre 
University Health Network 
Procedural Characteristics 
Kassimis et al. EuroIntervention 2014;10:694-699
Peter Munk Cardiac Centre 
University Health Network 
In-hospital Outcomes 
Kassimis et al. EuroIntervention 2014;10:694-699
Rotational atherectomy via the radial artery 
Peter Munk Cardiac Centre 
University Health Network 
is associated with similar procedural 
success when compared to the 
transfemoral route 
Mark A. Kotowycz, Sohail Q. Khan, Xavier Freixa, Joan Ivanov, Peter H. Seidelin, 
Christopher B. Overgaard, Vladimír Džavík 
Interventional Cardiology Program 
Peter Munk Cardiac Centre, University Health Network 
Toronto, Ontario, Canada 
Coronary Artery Disease (in press)
Peter Munk Cardiac Centre 
University Health Network 
Baseline Characteristics 
Variable Femoral 
n = 67 
Radial 
n = 52 
P value 
Age (years) 71.3 ± 10.5 71.0 ± 10.2 0.89 
Male 43 (64) 43 (83) 0.03 
Smoking (current or 
former) 
31 (46) 35 (67) 0.02 
Hypertension 58 (87) 41 (79) 0.26 
Dyslipidemia 58 (87) 44 (85) 0.76 
Diabetes 33 (49) 15 (29) 0.02 
Prior MI 25 (37) 12 (23) 0.10 
Prior PCI 27 (40) 21 (40) 0.86 
Prior CABG 11 (16) 9 (17) 0.93 
Prior CVA 3 (4) 3 (6) 0.75 
Presentation: 
Elective 39 (58) 39 (75) 
Urgent 
(ACS/NSTEMI) 
27 (40) 11 (21) 
Acute MI (STEMI) 1 (1) 2 (4) 
CCS Class 3 or 4 41 (61) 27 (52) 0.31 
Kotowycz et al. Coronary Artery Disease (in press)
Peter Munk Cardiac Centre 
University Health Network 
Procedural Characteristics 
Variable Femoral 
group 
n = 67 
Radial 
group 
n = 52 
P value 
Target Vessel: 
Left Main 3 (4) 1 (2) 0.63 
LAD 31 (46) 17 (33) 0.13 
LCx 6 (9) 11 (21) 0.06 
RCA 27 (40) 23 (44) 0.67 
ACC/AHA Lesion Type: 
A/B1 1 (1) 0 (0) 
B2 12 (18) 17 (33) 
C 54 (81) 35 (67) 
Ad Hoc PCI 7 (10) 6 (12) 0.85 
Ad Hoc Rotablation 32 (48) 34 (65) 0.06 
Kotowycz et al. Coronary Artery Disease (in press)
Peter Munk Cardiac Centre 
University Health Network 
Procedural Variables 
Variable Femoral group 
n = 67 
Radial group 
n = 52 
P value 
Access site crossover 0 (0) 3 (6) 0.08 
Guiding Catheter Size: 
6-French 20 (30) 36 (69) 
7-French 41 (62) 16 (31) 
8-French 6 (9) 0 (0) 
Average 6.79 ± 0.59 6.31 ± 0.47 < 0.001 
Number of Burrs: 
1 39 (58) 26 (50) 
2 26 (39) 24 (46) 
3 2 (3) 2 (4) 
Average Burr Size: 
Burr 1 1.34 ± 0.14 1.34 ± 0.13 0.74 
Burr 2 1.63 ± 0.16 1.62 ± 0.15 0.82 
Burr 3 1.88 ± 0.18 1.75 ± 0 0.42 
Kotowycz et al. Coronary Artery Disease (in press)
Peter Munk Cardiac Centre 
University Health Network 
Procedural variables 
Variable Femoral group 
n = 67 
Radial group 
n = 52 
P value 
Successful Rotablation 61 (91) 50 (96) 0.46 
Average number of stents 1.66 ± 1.20 1.79 ± 1.54 0.60 
Average stent diameter (mm) 2.97 ± 0.48 3.02 ± 0.47 0.60 
Stent length (mm) 40.3 ± 27.9 34.2 ± 27.3 0.25 
Use of drug-eluting stent (%) 27 (40) 20 (38) 0.71 
Use of GP IIb/IIIa Inhibitor (%) 35 (52) 28 (54) 0.86 
Insertion of pacing wire (%) 17 (25) 3 (6) 0.0057 
Insertion of IABP (%) 6 (9) 1 (2) 0.13 
Fluoroscopy time (minutes) 40.5 ± 21.2 43.8 ± 18.1 0.37 
Radiation exposure (cGy cm2) 27743 ± 16541 29939 ± 15192 0.50 
Contrast used (mL) 429 ± 182 384 ± 189 0.19 
Kotowycz et al. Coronary Artery Disease (in press)
Peter Munk Cardiac Centre 
University Health Network 
In-hospital Outcomes 
Complication Femoral 
n = 67 
Radial 
n = 52 
P value 
Death 3 (4.5) 1 (1.9) 0.63 
Peri-procedural MI (CK > 2 ULN) 6 (9.0) 3 (5.8) 0.73 
Urgent CABG 1 (1.5 ) 0 (0) 1.00 
Blood transfusion 3 (4.5) 0 (0) 0.26 
MACE (death, MI or urgent CABG) 10 (14.9) 4 (7.7) 0.26 
MACE or blood transfusion 11 (16.4) 4 (7.7) 0.18 
Kotowycz et al. Coronary Artery Disease (in press)
Peter Munk Cardiac Centre 
University Health Network 
Causes of Death 
Patient age/sex Indication Access Burr size (mm) Cause of death 
96/F ACS RF 1.25 Tamponade 2º to RA 
75/F ACS RF 1.25 Stent thrombosis 
76/M ACS LF 1.50 Palliative 
88/F STEMI RR 1.50 Bleed
Peter Munk Cardiac Centre 
University Health Network 
A long, dominant LCx lesion
Peter Munk Cardiac Centre 
University Health Network 
Unable to advance a balloon
Peter Munk Cardiac Centre 
University Health Network
Peter Munk Cardiac Centre 
University Health Network 
IN SUMMARY 
• Rotational Atherectomy via the transradial approach is 
feasible and associated with results that similar to 
those achieved utilizing the transfemoral approach 
• Bleeding complications may be decreased

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Dzavik V - AIMRADIAL 2014 - Rotablator and radial approach

  • 1. Peter Munk Cardiac Centre University Health Network Rotation Atherectomy and Radial vs. Femoral Approach Vladimír Džavík MD Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada AIM-RADIAL, Chicago, October 23, 2014
  • 2. Peter Munk Cardiac Centre University Health Network A recanalized RCA?
  • 3. Peter Munk Cardiac Centre University Health Network RAO view
  • 4. Peter Munk Cardiac Centre University Health Network After wiring
  • 5. Peter Munk Cardiac Centre University Health Network Rotawire floppy and a 1.5 mm burr
  • 6. Peter Munk Cardiac Centre University Health Network Predilation achieved easily
  • 7. Peter Munk Cardiac Centre University Health Network After predilation
  • 8. Peter Munk Cardiac Centre University Health Network After stenting – 2 DES
  • 9. from New Jersey Peter Munk Cardiac Centre University Health Network
  • 10. Peter Munk Cardiac Centre University Health Network Baseline Characteristics Gioia et al. Catheter and Cardiovasc Intervent 2000;51:234–238
  • 11. Peter Munk Cardiac Centre University Health Network Angiographic and Procedural Characteristics 3 patients discharged same day, 10 next day, 3 on Day 2
  • 12. Peter Munk Cardiac Centre University Health Network
  • 13. Peter Munk Cardiac Centre University Health Network Baseline Characteristics Watt & Oldroyd Catheter Cardiovasc Intervent 2009;74:550–554
  • 14. Peter Munk Cardiac Centre University Health Network Procedural Characteristics Watt & Oldroyd Catheter Cardiovasc Intervent 2009;74:550–554
  • 15. Peter Munk Cardiac Centre University Health Network In-hospital outcomes Watt & Oldroyd Catheter Cardiovasc Intervent 2009;74:550–554
  • 16. Peter Munk Cardiac Centre University Health Network
  • 17. Peter Munk Cardiac Centre University Health Network Baseline Characteristics Kassimis et al. EuroIntervention 2014;10:694-699
  • 18. Peter Munk Cardiac Centre University Health Network Procedural Characteristics Kassimis et al. EuroIntervention 2014;10:694-699
  • 19. Peter Munk Cardiac Centre University Health Network In-hospital Outcomes Kassimis et al. EuroIntervention 2014;10:694-699
  • 20. Rotational atherectomy via the radial artery Peter Munk Cardiac Centre University Health Network is associated with similar procedural success when compared to the transfemoral route Mark A. Kotowycz, Sohail Q. Khan, Xavier Freixa, Joan Ivanov, Peter H. Seidelin, Christopher B. Overgaard, Vladimír Džavík Interventional Cardiology Program Peter Munk Cardiac Centre, University Health Network Toronto, Ontario, Canada Coronary Artery Disease (in press)
  • 21. Peter Munk Cardiac Centre University Health Network Baseline Characteristics Variable Femoral n = 67 Radial n = 52 P value Age (years) 71.3 ± 10.5 71.0 ± 10.2 0.89 Male 43 (64) 43 (83) 0.03 Smoking (current or former) 31 (46) 35 (67) 0.02 Hypertension 58 (87) 41 (79) 0.26 Dyslipidemia 58 (87) 44 (85) 0.76 Diabetes 33 (49) 15 (29) 0.02 Prior MI 25 (37) 12 (23) 0.10 Prior PCI 27 (40) 21 (40) 0.86 Prior CABG 11 (16) 9 (17) 0.93 Prior CVA 3 (4) 3 (6) 0.75 Presentation: Elective 39 (58) 39 (75) Urgent (ACS/NSTEMI) 27 (40) 11 (21) Acute MI (STEMI) 1 (1) 2 (4) CCS Class 3 or 4 41 (61) 27 (52) 0.31 Kotowycz et al. Coronary Artery Disease (in press)
  • 22. Peter Munk Cardiac Centre University Health Network Procedural Characteristics Variable Femoral group n = 67 Radial group n = 52 P value Target Vessel: Left Main 3 (4) 1 (2) 0.63 LAD 31 (46) 17 (33) 0.13 LCx 6 (9) 11 (21) 0.06 RCA 27 (40) 23 (44) 0.67 ACC/AHA Lesion Type: A/B1 1 (1) 0 (0) B2 12 (18) 17 (33) C 54 (81) 35 (67) Ad Hoc PCI 7 (10) 6 (12) 0.85 Ad Hoc Rotablation 32 (48) 34 (65) 0.06 Kotowycz et al. Coronary Artery Disease (in press)
  • 23. Peter Munk Cardiac Centre University Health Network Procedural Variables Variable Femoral group n = 67 Radial group n = 52 P value Access site crossover 0 (0) 3 (6) 0.08 Guiding Catheter Size: 6-French 20 (30) 36 (69) 7-French 41 (62) 16 (31) 8-French 6 (9) 0 (0) Average 6.79 ± 0.59 6.31 ± 0.47 < 0.001 Number of Burrs: 1 39 (58) 26 (50) 2 26 (39) 24 (46) 3 2 (3) 2 (4) Average Burr Size: Burr 1 1.34 ± 0.14 1.34 ± 0.13 0.74 Burr 2 1.63 ± 0.16 1.62 ± 0.15 0.82 Burr 3 1.88 ± 0.18 1.75 ± 0 0.42 Kotowycz et al. Coronary Artery Disease (in press)
  • 24. Peter Munk Cardiac Centre University Health Network Procedural variables Variable Femoral group n = 67 Radial group n = 52 P value Successful Rotablation 61 (91) 50 (96) 0.46 Average number of stents 1.66 ± 1.20 1.79 ± 1.54 0.60 Average stent diameter (mm) 2.97 ± 0.48 3.02 ± 0.47 0.60 Stent length (mm) 40.3 ± 27.9 34.2 ± 27.3 0.25 Use of drug-eluting stent (%) 27 (40) 20 (38) 0.71 Use of GP IIb/IIIa Inhibitor (%) 35 (52) 28 (54) 0.86 Insertion of pacing wire (%) 17 (25) 3 (6) 0.0057 Insertion of IABP (%) 6 (9) 1 (2) 0.13 Fluoroscopy time (minutes) 40.5 ± 21.2 43.8 ± 18.1 0.37 Radiation exposure (cGy cm2) 27743 ± 16541 29939 ± 15192 0.50 Contrast used (mL) 429 ± 182 384 ± 189 0.19 Kotowycz et al. Coronary Artery Disease (in press)
  • 25. Peter Munk Cardiac Centre University Health Network In-hospital Outcomes Complication Femoral n = 67 Radial n = 52 P value Death 3 (4.5) 1 (1.9) 0.63 Peri-procedural MI (CK > 2 ULN) 6 (9.0) 3 (5.8) 0.73 Urgent CABG 1 (1.5 ) 0 (0) 1.00 Blood transfusion 3 (4.5) 0 (0) 0.26 MACE (death, MI or urgent CABG) 10 (14.9) 4 (7.7) 0.26 MACE or blood transfusion 11 (16.4) 4 (7.7) 0.18 Kotowycz et al. Coronary Artery Disease (in press)
  • 26. Peter Munk Cardiac Centre University Health Network Causes of Death Patient age/sex Indication Access Burr size (mm) Cause of death 96/F ACS RF 1.25 Tamponade 2º to RA 75/F ACS RF 1.25 Stent thrombosis 76/M ACS LF 1.50 Palliative 88/F STEMI RR 1.50 Bleed
  • 27. Peter Munk Cardiac Centre University Health Network A long, dominant LCx lesion
  • 28. Peter Munk Cardiac Centre University Health Network Unable to advance a balloon
  • 29. Peter Munk Cardiac Centre University Health Network
  • 30. Peter Munk Cardiac Centre University Health Network IN SUMMARY • Rotational Atherectomy via the transradial approach is feasible and associated with results that similar to those achieved utilizing the transfemoral approach • Bleeding complications may be decreased