1. The document discusses lessons learned from fostering entrepreneurship activities in Central-Eastern Europe through various workshops, trainings, grants, and clusters. 2. It notes that while Hungary has laws mandating technology transfer offices (TTOs) at universities, in practice there are only 7 functioning TTOs, and they are still limited by academics. 3. The document outlines the goals, components, and lessons from various entrepreneurship and incubation programs, finding that structured mentoring, coaching, and introducing trainees to real case studies through a step-by-step process are most effective.

1. Fostering entrepreneurship activities in the life sciences sector Failures and successes of workshops, trainings, grants and clusters in Central-Eastern Europe Zsombor Lacza, CEO Semmelweis Innovations

2. Lessons from Hungary There are only 7 working TTOs in Hungary - despite the innovation act which mandates a TTO at every university The minimum size of a TTO is 8 FTE trained personnel and about 150 m HUF yearly budget Entrepreneurial activities are still repressed by the academics * 100 research groups, 3 FTE researcher each, www.record-network.net ** after 2 years in operation, before the formation of Semmelweis Innovations expected* 2006** 2008 n of disclosures 300 13 120 radical innovation 2 0 0 patent 100 2 13 outlicensing 4 0 2 spin-off formation 30 1 0

3. Lessons from MIT entrepreneurship is the key element in new economic value creation (not money, education, industry, etc.) entrepreneurship can be increased dramatrically at a university, but it needs several interconnecting actions more than 1000 MIT alumni founded a company, only 30 of them did it through classical tech transfer (2000).

4. What is the goal? 1. Create an innovative niche environment 2. Build a community 3. Nurture projects

5. Incubators anyone? 50% Govt. grant - grant returned, no incubator 40% EU grant - granted, office space built 80% Govt. grant for virtual incubation - withdrawn 70% EU grant for building - withdrawn 70% EU grant for building - withdrawn ? Govt grant - pending

6. Innovative Environment training studio internet-cafe shared meeting rooms labs for rent

7. Administration online project management system standardized lab notebooks voucher-based consultancy

8. Building a community PhD level: IP, management courses Researcher level: faculty visits Project managers = future CEOs SIBE - practical learning researcher + manager + mentor 6 steps of business planning: model, IP, market, finance, design, presentation personalized business development

9. program overview

10. What do the students get? Minimized contact times - suitable for distance learning or for those who have a day job 3 weeks of your time in Budapest 2 hours on-line per week 6 + 6 half days in distance learning Hard skills: business models and planning, IP and marketing strategies, corporate design, team building with a Biotech focus Soft skills: self-assessment, team roles, negotiation skills, problem-solving, time-management www.semmelweisinnovations.com

11. What works best? The structure of intensive contact weeks plus working from home Mentoring: business consultants are best Coaching: to relieve stress and solve conflicts Stepwise introduction into real case studies Providing innovative tools to work with Biotech (=life sciences) focus Structured handouts and limited space Trainers trained to meet school requirements

12. What works least? Off-topic inventions Any changes in the Trimaran part (course+rotation+voucher) Trainers with great knowledge but boring personality Trainers who cannot adapt to school rules Full handouts Tools without excessive practice and repetitions Unreal or canned cases (=case studies)

13. Results of training 47% of them has got a higher income than what (s)he expected 50% of them could not have reached the desired income-level without the program

14. Results of projects Hyperbaric O2 therapy - expansion capital Zebrafish toxicity - service company startup New X-Ray and CT modality - tech startup Drug repositioning - tech startup Hand cleaning - medtech startup depression: small money takes you farther, high motivation and risk tolerance from people greatest risk: sluggish and sometimes incompetent administration kills the opportunities.

15. www.semmelweisinnovations.com