A shoulder dislocation occurs when the humerus separates from the scapula at the glenohumeral joint. The most common type is an anterior dislocation, which can be reduced using techniques like external rotation or traction-countertraction. Complications of shoulder dislocation include recurrent dislocations, fractures, soft tissue injuries like Hill-Sachs or Bankart lesions, and nerve or vascular injuries. Careful examination is needed before and after reduction to identify any associated injuries.
Claw Hand,Definition,Causes,Types,Symptoms and ManagementDr.Md.Monsur Rahman
Dr.Md.Monsur Rahman, Bachelor of Physiotherapy (BPT), Master of Physiotherapy (MPT) in Musculoskeletal Disorders, ABC-Spine in Osteopathic Approach,
Maharishi Markandeshwar (Deemed to be University), Ambala -Haryana.
Claw Hand,Definition,Causes,Types,Symptoms and ManagementDr.Md.Monsur Rahman
Dr.Md.Monsur Rahman, Bachelor of Physiotherapy (BPT), Master of Physiotherapy (MPT) in Musculoskeletal Disorders, ABC-Spine in Osteopathic Approach,
Maharishi Markandeshwar (Deemed to be University), Ambala -Haryana.
Dislocations of the bone by dr amna hussainDureSameen19
A dislocation is a separation of two bones where they meet at a joint. This injury can be very painful and can temporarily deform and immobilize the joint. The most common locations for a dislocation are shoulders and fingers, but can also occur in elbows, knees and hips. The cause is often a fall or a blow, sometimes from playing a contact sport.
JOINT DISLOCATION of hip knee and shoulder PART-2.pptxrammmramm000
JOINT DISLOCATION of hip knee and shoulder
JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder
JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder
JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder
JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder
JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder
JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip knee and shoulder JOINT DISLOCATION of hip kn
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. • A dislocated shoulder occurs when the humerus separates from the scapula at
the glenohumeral joint.
• A partial dislocation (subluxation) means the humerus is partially out of the
socket (glenoid). A complete dislocation means it is all the way out of the socket.
( American Academy Of Orthopaedic Surgeon).
• Most common dislocation
• Common in young/athletic patients ( recurrence > 90% if < 25 y/o)
• a/w labral tears (< 40 y/o) and rotator cuff ( > 40 y/o)
• a/w fracture of tuberosity/ glenoid rim ( Bony bankart)
5. • Mechanisms of injury are usually traumatic but may vary.
• Mechanisms may include sports, assaults, falls, seizures, throwing an
object, reaching to catch an object, forceful pulling on the arm, reaching
for an object, turning over in bed or combing hair.
• Specific mechanisms or historical facts may be suggestive of certain types
of dislocations such as lightning injuries, electrical injuries and seizure with
posterior dislocations
• Throwing a ball, a punch, forceful pulling of the arm, fall on out-stretch
hand, shoulder is abducted and externally rotated with an anterior
dislocation
• Axial loading of an extremely abducted arm with inferior dislocation.
6. • Pain
• Inability to move shoulder/ decreased range of motion of the affected
extremity
• Deformity of shoulder
7. Anterior shoulder dislocation
• sub-coracoid dislocation, sub-glenoid, subcalvicular, intrathoracic (rare)
• Arm is held in slight abduction and external rotation.
• Shoulder is "squared off" (ie, boxlike) with loss of deltoid contour compared with contralateral side.
• Humeral head is palpable anteriorly (subcoracoid region, beneath the clavicle).
• Patient resists abduction and internal rotation and is unable to touch the opposite shoulder.
• Compare bilateral radial pulses to help rule out vascular injury.
• In all cases, evaluate the axillary nerve before and after reduction by testing both pinprick sensation in the "regimental badge"
area of the deltoid and palpable contraction of the deltoid during attempted abduction.
• Evaluate sensory and motor function of the musculocutaneous and radial nerves.
8. Posterior shoulder dislocation
• Arm is held in adduction and internal rotation.
• Anterior shoulder is "squared off" and flat with prominent coracoid
process.
• Shoulders may look identical in bilateral dislocation, making it a commonly
missed injury.
• Posterior shoulder is full with humeral head palpable beneath the
acromion process.
• Patient resists external rotation and abduction.
• Neurovascular deficits are infrequent.
9. Inferior (luxatio erecta) shoulder dislocation
• Arm is fully abducted with elbow commonly flexed on or behind
head.
• Humeral head may be palpable on the lateral chest wall.
10. • Absence of normal contour of shoulder
• Bryant’s sign – Anterior axillary fold looks elongated
• Callaway’s sign – Axillary girth get increased
• Duga’s test – Inability to touch the opposite shoulder by affected hand
• Displaced head is palpable below clavicle or coracoid process of axilla
• Deformity- Shoulder extended,abducted, external rotation
• Hamilton ruler test – A ruler can touch acromion process and lateral
epicondyle at the same time.
11. Shoulder trauma series[7] - Anteroposterior (AP) and axillary or scapular "Y" views:
• Anterior dislocation is characterized by subcoracoid position of the humeral head in the AP view. The
dislocation is often more obvious in a scapular "Y" view, where the humeral head lies anterior to the "Y." In
an axillary view, the "golf ball" (ie, humeral head) is said to have fallen anterior to the "tee" (ie, glenoid).
• In posterior dislocation, the AP view may show a normal walking stick contour of the humeral head, or it
may resemble a light bulb or ice cream cone, depending upon the degree of rotation. The scapular "Y" view
reveals the humeral head behind the glenoid (the center of the "Y"). In an axillary view, the "golf ball" falls
posteriorly off the "tee." [8, 9]
• In inferior dislocation (luxatio erecta), the AP view may show the arm raised over the head with the radial
head inferior to the glenoid.
Pre-reduction films
• These are commonly performed to document the nature of the dislocation and to establish the existence of
any associated pathology, such as a Hill-Sachs lesion or other humeral fractures.
• In cases where patients have experienced repeated anterior dislocations, prereduction films may not be
necessary prior to attempts at reduction. [10]
Post-reduction films:
• These confirm relocation of the humerus and may reveal new or previously obscured pathology.
Postreduction immobilization is imperative.
12. • In Kocher's original method, bend the arm at the elbow, press it against the body, rotate outwards until resistance is felt. Lift the
externally rotated upper part of the arm in the sagittal plane as far as possible forwards and finally turn inwards slowly.
• The Stimson technique requires that the patient lie prone on the bed with the dislocated arm hanging over the side. Traction is
provided by up to 10 kg of weight attached to the wrist or above the elbow. Apply gentle internal/external humeral rotation.
Reduction may take 20-30 minutes.
• In the external rotation method, while the patient lies supine, adduct the arm and flex it to 90° at the elbow. Slowly rotate the arm
externally, pausing for pain. Reduce the shoulder before reaching the coronal plane. Often successful, this procedure requires only
one physician and little force (see Special Concerns).
• For traction-countertraction, while the patient lies supine, apply axial traction to the arm with a sheet wrapped around the
forearm and the elbow bent at 90°. An assistant should apply countertraction using a sheet wrapped under the arm and across the
chest while the shoulder is gently rotated internally and externally to disengage the humeral head from the glenoid.
• Scapular rotation is a less traumatic technique and has success rates of more than 90% in experienced hands, often without
sedation. With the patient lying prone, apply manual traction or 5-15 lb of hanging weight to the wrist. After relaxation, rotate the
inferior tip of the scapula medially and the superior aspect laterally. Alternatively, the patient can be seated while an assistant
provides traction-countertraction by pulling on the wrist with one hand and bracing the upper chest with the other. The same
scapular rotation is then performed.
13. • For reduction of a posterior dislocation, apply gentle, prolonged axial
traction on the humerus. Then, add gentle anterior pressure while
coaxing the humeral head over the glenoid rim. Slow external rotation
may be needed.
• For reduction of an inferior dislocation, maintain gentle axial traction
on the humerus while gentle abduction is applied. Apply
countertraction across the ipsilateral shoulder. Following reduction,
slowly adduct the arm. Buttonholing of the humeral head through the
capsule usually requires open reduction.
14. • Complications
• See the list below:
• Recurrent shoulder dislocation (See Prognosis).
• Fractures and soft-tissue injuries (See Other Problems to be Considered.) Hill-Sachs lesions occur when the edge of the glenoid causes an impaction fracture in the posterolateral
aspect of the humeral head during anterior dislocation and in the anterolateral aspect in posterior dislocation (referred to as a "reverse Hill-Sachs" lesion).
• A Bankart lesion is fracture of the anterior rim of the glenoid labrum associated with joint capsule rupture and inferior glenohumeral ligament injury. Significantly displaced
anterior or posterior glenoid rim fractures require operative management. Most initial shoulder dislocations produce a Bankart lesion, particularly in younger patients.
• Fracture of the greater tuberosity, acromion, coracoid, clavicle, and humeral neck also occur.
• Rotator cuff traction injury is most common in elderly patients and in association with inferior dislocations. This is a commonly missed injury, with an average time of 7 months
from injury to diagnosis of rotator cuff rupture in patients older than 40 years.
• Nerve injury (See Other Problems to be Considered.) Approximately 3% (and higher in some series) of dislocations involve injury to the axillary nerve. Injury may resolve
spontaneously or require surgical exploration and possible nerve grafting.
• Patients exhibit numbness in the area of the deltoid muscle and weakness with abduction and external rotation.
• Axillary nerve injury does not change initial treatment, but pre-reduction and post-reduction neurologic examinations are important.
• Radial nerve injury should also be determined. The axillary and radial nerves both arise from the posterior cord. The thumb, wrist, and elbow will be weak on extension, and the
dorsal hand will be numb.
• Vascular injury (See Other Problems to be Considered.) Axillary artery injuries are rare but have been reported to occur with anterior, inferior, and intra-thoracic dislocations.
Especially susceptible are older adults with atherosclerotic axillary arteries. Arterial injury may be associated with decreased radial pulse.
• Lateral chest wall ecchymosis with associated axillary hematoma and bruit may be noted on physical examination.
• Angiography should be considered with any brachial plexus injury.