It is important to opt for a fertility treatment from a doctor that gives you higher chances to conceive. If the IVF doctor success rates are not high then, it’s a total waste of hopes, money and time. Your IVF success rate depends on the doctor you are seeking the treatment from. Check out the defined list of Best 15 IVF Doctors in Pune who has the high success rates with best IVF treatment and care.
Leaf Society is promoting the concept of dignified sanitation solutions through behaviour change communication mechanisms, diverging from low cost toilet approach, using children as agents of change, promotion of sanitation societies among women and leveraging funds from various sources.
Growth prospects of children after discharge from malnutrition treatment cent...POSHAN
This presentation was made by Dr. Jyoti Sharma (Public Health Foundation of India) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Antenatal care and counseling measures increase iron and folic acid receipt a...POSHAN
This study examined individual and facility-level factors associated with iron and folic acid (IFA) receipt and consumption among pregnant women in Bihar, India. The study found that higher quality antenatal care, as measured by practices and counseling, was positively associated with both IFA receipt and consumption. Receipt was also associated with earlier antenatal care enrollment and more visits. Consumption was more likely when the local health sub-center had IFA in stock. Significant variation between health facilities remained after accounting for individual factors. Ensuring consistent IFA supply and high quality antenatal care is important for improving IFA outcomes.
Probiotics have been shown in meta-analyses to reduce rates of necrotizing enterocolitis (NEC) and mortality in preterm infants. However, there is still resistance to implementing their use due to concerns about the variability of probiotic strains and regimes used across studies, lack of data specifically in extremely low birth weight infants, and unproven long-term safety. The author argues that these objections are not valid given the consistent beneficial effects seen across probiotic types, the biological plausibility of the effects, and the lack of documented safety issues in the thousands of infants exposed to probiotics in clinical trials. Widespread adoption of probiotic supplementation could significantly reduce NEC rates and mortality in preterm infants.
Research into mealtimes and older people with dementiaRoger Watson
This document discusses research into helping older people with dementia during mealtimes. Dementia can cause problems with intelligence, memory, language, wandering, aggression and more. It also raises ethical questions around feeding. The Edinburgh Feeding Evaluation in Dementia scale is presented as the most validated measure of feeding difficulty. Several studies testing interventions like music or Montessori-based activities found positive outcomes, though more rigorous research is still needed. Factors like environment, social interaction and individualizing care can help promote independence in feeding for longer. Spaced retrieval training also showed promise in reducing mealtime difficulties. While numbers of those with dementia will rise, targeted interventions may help alleviate associated problems like eating.
Research into mealtimes and older people with dementia.pptxRoger Watson
This document discusses research into helping older people with dementia during mealtimes. Dementia can cause problems with intelligence, memory, language, wandering, aggression and more. It also discusses the ethical issues around feeding those with dementia. The Edinburgh Feeding Evaluation in Dementia scale is presented as the most widely used and validated measure of feeding difficulty. Several studies testing interventions like music or Montessori-based activities found positive outcomes, though more rigorous research is still needed. Spaced retrieval training was found to reduce mealtime difficulties and promote independence. Creating the right environment, social interactions and individualized care can help prolong eating ability in dementia patients.
It is important to opt for a fertility treatment from a doctor that gives you higher chances to conceive. If the IVF doctor success rates are not high then, it’s a total waste of hopes, money and time. Your IVF success rate depends on the doctor you are seeking the treatment from. Check out the defined list of Best 15 IVF Doctors in Pune who has the high success rates with best IVF treatment and care.
Leaf Society is promoting the concept of dignified sanitation solutions through behaviour change communication mechanisms, diverging from low cost toilet approach, using children as agents of change, promotion of sanitation societies among women and leveraging funds from various sources.
Growth prospects of children after discharge from malnutrition treatment cent...POSHAN
This presentation was made by Dr. Jyoti Sharma (Public Health Foundation of India) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Antenatal care and counseling measures increase iron and folic acid receipt a...POSHAN
This study examined individual and facility-level factors associated with iron and folic acid (IFA) receipt and consumption among pregnant women in Bihar, India. The study found that higher quality antenatal care, as measured by practices and counseling, was positively associated with both IFA receipt and consumption. Receipt was also associated with earlier antenatal care enrollment and more visits. Consumption was more likely when the local health sub-center had IFA in stock. Significant variation between health facilities remained after accounting for individual factors. Ensuring consistent IFA supply and high quality antenatal care is important for improving IFA outcomes.
Probiotics have been shown in meta-analyses to reduce rates of necrotizing enterocolitis (NEC) and mortality in preterm infants. However, there is still resistance to implementing their use due to concerns about the variability of probiotic strains and regimes used across studies, lack of data specifically in extremely low birth weight infants, and unproven long-term safety. The author argues that these objections are not valid given the consistent beneficial effects seen across probiotic types, the biological plausibility of the effects, and the lack of documented safety issues in the thousands of infants exposed to probiotics in clinical trials. Widespread adoption of probiotic supplementation could significantly reduce NEC rates and mortality in preterm infants.
Research into mealtimes and older people with dementiaRoger Watson
This document discusses research into helping older people with dementia during mealtimes. Dementia can cause problems with intelligence, memory, language, wandering, aggression and more. It also raises ethical questions around feeding. The Edinburgh Feeding Evaluation in Dementia scale is presented as the most validated measure of feeding difficulty. Several studies testing interventions like music or Montessori-based activities found positive outcomes, though more rigorous research is still needed. Factors like environment, social interaction and individualizing care can help promote independence in feeding for longer. Spaced retrieval training also showed promise in reducing mealtime difficulties. While numbers of those with dementia will rise, targeted interventions may help alleviate associated problems like eating.
Research into mealtimes and older people with dementia.pptxRoger Watson
This document discusses research into helping older people with dementia during mealtimes. Dementia can cause problems with intelligence, memory, language, wandering, aggression and more. It also discusses the ethical issues around feeding those with dementia. The Edinburgh Feeding Evaluation in Dementia scale is presented as the most widely used and validated measure of feeding difficulty. Several studies testing interventions like music or Montessori-based activities found positive outcomes, though more rigorous research is still needed. Spaced retrieval training was found to reduce mealtime difficulties and promote independence. Creating the right environment, social interactions and individualized care can help prolong eating ability in dementia patients.
Gloria Folson and Futoshi Yamauchi
Side Event: How Japan’s know-how can help address food and nutrition challenges in the developing world
Tokyo Nutrition for Growth (N4G) Summit 2021
NOV 30, 2021
EOP Evaluation of BASICS iCCM Project Benin 2009 to 2012_Paul Freeman_4.25.13CORE Group
This document summarizes an evaluation of a USAID-funded integrated community case management (iCCM) project in Benin from 2009 to 2012. The project trained over 1,000 community health workers (CHWs) across 5 health zones to treat common childhood illnesses like malaria, pneumonia, and diarrhea. The evaluation found that CHWs appropriately treated over 40,000 cases of malaria and referred over 7,000 cough/pneumonia cases. Households with a CHW had less delay in seeking care, were more likely to initially see a CHW rather than a traditional provider or store, and mothers were highly satisfied with CHW care. The evaluation identified lessons like the importance of collaboration between CHWs and local organizations to support sustainability
FOOT ASSESSMENT AND KNOWLEDGE AMONG PATIENTS ATTENDING DIABETIC CLINIC IN SHI...Lutfi Abdallah
This document summarizes a research study on foot assessment and knowledge among diabetic patients in Shinyanga, Tanzania. The study assessed 268 diabetic patients and 3 health care workers. It found that nearly half of patients had poor knowledge of foot care. Higher education level, type 1 diabetes, and no history of foot infection were associated with better knowledge. Busy clinic schedules and lack of education materials hindered thorough foot assessments by health care workers. The study recommends improved education for patients and providers, as well as designating staff specifically for foot care services.
Interventions with potential to reduce sedentary time in adults: What's the e...Health Evidence™
The document provides information about an upcoming webinar on interventions to reduce sedentary time in adults. It includes details about participating in polls during the webinar, obtaining the presentation materials afterwards, and contact information. Participation in the anonymous polling questions is voluntary and intended to stimulate discussion for professional development purposes.
The study compared the reliability and diagnostic accuracy of routine NHS laboratories and a research laboratory in diagnosing urinary tract infections (UTIs) in young children. The research laboratory showed substantially better agreement with predefined signs/symptoms of UTIs and with a clean-catch urine sample method. The NHS laboratories appeared to overdiagnose UTIs from nappy pad samples due to failure to distinguish contamination. The implications are that NHS laboratories may benefit from adopting the research laboratory's standardized methods, and clinicians should focus on obtaining higher-quality clean-catch urine samples for improved UTI diagnosis in young children.
Dr. Jean-Pierre Vaillancourt - Can You Keep High Path Avian Influenza from En...John Blue
Can You Keep High Path Avian Influenza from Entering Your Operation? - Dr. Jean-Pierre Vaillancourt, University of Montreal, Quebec, from the 2016 NIAA Annual Conference: From Farm to Table - Food System Biosecurity for Animal Agriculture, April 4-7, 2016, Kansas City, MO, USA.
More presentations at http://www.trufflemedia.com/agmedia/conference/2016_niaa_farm_table_food_system_biosecurity
Cleaning: It’s everyone’s responsibility. Review environmental cleaning procedures for all perioperative patient care areas (preoperative, OR, postoperative, and sterile processing). This information was originally shared in an AORN webinar, which is also available for free on demand at http://bit.ly/IHTNnp. One contact hour is available for the webinar through November 13, 2014. Learn more about AORN educational events at www.aorn.org/Events.
Research in pediatrician office - my story! NORC Aug 2019 New DelhiGaurav Gupta
Presented in NORC - Aug 2019 - National Original Research convention, discussion of Flu like illnesses and the Flu vaccination and drug utilization reviews and prescription audits and various other original research presented and published by Dr. Gaurav Gupta in his years of clinical practice, including yellow fever, Complementary medicines, drug costs and prescriptions analysis
Shine the Endoscopic Light on Oropharyngeal DysphagiaMichelleCimoli
Michelle Cimoli - DIG July 2017
Feel free to refer to the information contained in this presentation, but please acknowledge the original author, which is noted at the beginning of the presentation.
Bicycle Helmet Promotion in Children: What's the Evidence?Health Evidence™
Health Evidence - lead by Dr. Maureen Dobbins - hosted a webinar, funded by the Canadian Institutes of Health Research (KTB-112487), on bicycle helmet promotion interventions in children, presenting key messages, and implications for practice on Thursday October 25, 2012 at 1:00 pm EST.
This webinar interpreted the evidence in the following review:
Owen, R., Kendrick, D., Mulvaney, C., Coleman, T., Royal, S. (2011). Non-legislative interventions for the promotion of cycle helmet wearing by children. Cochrane Database of Systematic Reviews, 2011(11): Art. No.: CD003985.
This study aimed to identify pregnant women's perceptions of barriers to male involvement in antenatal care in Sekondi, Ghana. The study found that socio-demographic factors like partners' age, marital status, and living arrangement influenced perceptions. Socio-cultural factors like attitudes towards gender roles and masculinity also impacted perceptions. Health facility factors such as long wait times and distance to facilities were perceived as barriers. The study provides insight into women's views of barriers that could be addressed to increase male participation in antenatal care in Ghana.
Dr Deirdre Connolly , Trinity College Dublin (TCD)Investnet
Occupational therapy interventions for homecare clients in Dublin showed promising results in a pilot study. The interventions focused on improving functional abilities for daily activities. Quantitative measures found significant improvements in self-care and mobility scores after therapy. Qualitatively, clients reported gaining independence with activities like dressing, shopping, and social participation. Homecare hours were reduced for some clients, indicating potential cost savings. Larger studies are still needed, but initial findings suggest occupational therapy can benefit homecare clients' independence and quality of life.
An analysis of water quality and health data from a prospective study in peri-urban Zambia found that Enterococci counts in household drinking water, but not E. coli or total coliform counts, were positively associated with self-reported gastrointestinal illness among residents. Higher levels of Enterococci in water were linked to increased odds of gastrointestinal symptoms. While reported water treatment was initially associated with lower illness, this relationship did not remain significant after adjusting for other factors. The findings suggest Enterococci may be a better indicator than E. coli for predicting gastrointestinal disease risk from drinking water in this urban setting.
Enterococci but not E. coli counts in drinking water are positively associate...Michelo Simuyandi
Background and Objective
Studies of the association between faecal indicator bacteria and diarrhoeal disease risk have yielded mixed findings that range from no association to significant associations. We conducted a prospective study collecting repeated measures of water quality and health indicators and related covariates at household level in a peri-urban area south of Lusaka. The aim was to measure the association between the levels of Enterococci and E. coli in household drinking water and self-reported highly credible gastrointestinal illness (HCGI) experienced by household members in the previous seven days.
Methods
We carried out a prospective household based observational study of 290 households which involved household interviews, household observations and testing of household stored drinking water and source water for bacterial indicators of faecal contamination. Residents were interviewed regarding demographics, socio-economic status, drinking water access, treatment and storage, hygiene and sanitation practices, household-level environmental health related exposures, diarrhoea and other gastro-intestinal symptoms. The associations between Enterococci, E. coli, total coliforms in household drinking water and the HCGI experienced by household members were investigated using mixed-effects logistic regression.
Results
Univariate analyses showed Enterococci count was significantly associated with HCGI (OR 26.55 CI: 1.45, 486.04)for unadjusted and (OR 31.33 CI:(2.13, 461.73) for the adjusted. that Log2, but not E. coli or total coliforms,. For every doubling of enterococci count, the odds of HCGI increased by a factor of 1.54 (95% CI :( 1.13, 2.10), p=0.01). Reported treatment of household water (OR 0.41, p<0.01),><0.01) were negatively associated with HCGI, whilst having a place to wash hands near toilet was positively associated with HCGI outcomes (OR 2.12, p=0.03). A positive association of HCGI with age under 5 in the household did not reach statistical significance (OR 1.53, p=0.07.). In a multivariate model, log2 Enterococci count remained significantly associated with HCGI. A doubling of enterococci count increased the odds of HCGI by a factor of 1.67 (95% CI: 1.09, 2.56, p=0.02, after adjustment for water treatment.
Conclusion
In this urban setting, enterococci counts have a stronger association with HCGI than E.coli or total coliform count.
Enterococci but not E. coli counts in drinking water are positively associate...Michelo Simuyandi
Background and Objective
Studies of the association between faecal indicator bacteria and diarrhoeal disease risk have yielded mixed findings that range from no association to significant associations. We conducted a prospective study collecting repeated measures of water quality and health indicators and related covariates at household level in a peri-urban area south of Lusaka. The aim was to measure the association between the levels of Enterococci and E. coli in household drinking water and self-reported highly credible gastrointestinal illness (HCGI) experienced by household members in the previous seven days.
Methods
We carried out a prospective household based observational study of 290 households which involved household interviews, household observations and testing of household stored drinking water and source water for bacterial indicators of faecal contamination. Residents were interviewed regarding demographics, socio-economic status, drinking water access, treatment and storage, hygiene and sanitation practices, household-level environmental health related exposures, diarrhoea and other gastro-intestinal symptoms. The associations between Enterococci, E. coli, total coliforms in household drinking water and the HCGI experienced by household members were investigated using mixed-effects logistic regression.
Results
Univariate analyses showed Enterococci count was significantly associated with HCGI (OR 26.55 CI: 1.45, 486.04)for unadjusted and (OR 31.33 CI:(2.13, 461.73) for the adjusted. that Log2, but not E. coli or total coliforms,. For every doubling of enterococci count, the odds of HCGI increased by a factor of 1.54 (95% CI :( 1.13, 2.10), p=0.01). Reported treatment of household water (OR 0.41, p<0.01),><0.01) were negatively associated with HCGI, whilst having a place to wash hands near toilet was positively associated with HCGI outcomes (OR 2.12, p=0.03). A positive association of HCGI with age under 5 in the household did not reach statistical significance (OR 1.53, p=0.07.). In a multivariate model, log2 Enterococci count remained significantly associated with HCGI. A doubling of enterococci count increased the odds of HCGI by a factor of 1.67 (95% CI: 1.09, 2.56, p=0.02, after adjustment for water treatment.
Conclusion
In this urban setting, enterococci counts have a stronger association with HCGI than E.coli or total coliform count.
Status in terms of water and sanitation of some of the oldest refugee camp in Gaza.
The slides have not been converted properly. Some labels are superimposed and on top of others. Furthermore, most of them have got animations...it’s a pity since the whole presentation can’t be appreciated properly.
This document discusses the development and use of a rapid, non-invasive at-home HIV self-test called OraQuick. It describes:
1) The need for novel testing approaches to reach more individuals who have never been tested for HIV.
2) Details of the OraQuick test, including its accuracy (>99%), ease of use involving a oral fluid sample, and 30 month shelf life.
3) Clinical trial results showing the test had a 99.8% accuracy rate when used unsupervised and identified previously undiagnosed HIV-positive individuals, though some reported incorrect negative results.
4) Support resources like a 24/7 support center to help individuals interpret results and get linked to care
This document summarizes a community entry and diagnosis conducted in Emanyinya Sub-Location, Vihiga County. A team of students and supervisors assessed the health determinants and status of the community. They found that the majority of households had good ventilation but poor sanitation. Common diseases affecting adults and children included malaria, respiratory infections, and intestinal worms. While vaccination rates were high, nutrition and family planning posed challenges. The team recommended organizing medical camps and ensuring tutors are well-prepared to support students during community placements.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
More Related Content
Similar to Impact of Shared Sanitation Facilities in Madhya Pradesh, India (2012)
Gloria Folson and Futoshi Yamauchi
Side Event: How Japan’s know-how can help address food and nutrition challenges in the developing world
Tokyo Nutrition for Growth (N4G) Summit 2021
NOV 30, 2021
EOP Evaluation of BASICS iCCM Project Benin 2009 to 2012_Paul Freeman_4.25.13CORE Group
This document summarizes an evaluation of a USAID-funded integrated community case management (iCCM) project in Benin from 2009 to 2012. The project trained over 1,000 community health workers (CHWs) across 5 health zones to treat common childhood illnesses like malaria, pneumonia, and diarrhea. The evaluation found that CHWs appropriately treated over 40,000 cases of malaria and referred over 7,000 cough/pneumonia cases. Households with a CHW had less delay in seeking care, were more likely to initially see a CHW rather than a traditional provider or store, and mothers were highly satisfied with CHW care. The evaluation identified lessons like the importance of collaboration between CHWs and local organizations to support sustainability
FOOT ASSESSMENT AND KNOWLEDGE AMONG PATIENTS ATTENDING DIABETIC CLINIC IN SHI...Lutfi Abdallah
This document summarizes a research study on foot assessment and knowledge among diabetic patients in Shinyanga, Tanzania. The study assessed 268 diabetic patients and 3 health care workers. It found that nearly half of patients had poor knowledge of foot care. Higher education level, type 1 diabetes, and no history of foot infection were associated with better knowledge. Busy clinic schedules and lack of education materials hindered thorough foot assessments by health care workers. The study recommends improved education for patients and providers, as well as designating staff specifically for foot care services.
Interventions with potential to reduce sedentary time in adults: What's the e...Health Evidence™
The document provides information about an upcoming webinar on interventions to reduce sedentary time in adults. It includes details about participating in polls during the webinar, obtaining the presentation materials afterwards, and contact information. Participation in the anonymous polling questions is voluntary and intended to stimulate discussion for professional development purposes.
The study compared the reliability and diagnostic accuracy of routine NHS laboratories and a research laboratory in diagnosing urinary tract infections (UTIs) in young children. The research laboratory showed substantially better agreement with predefined signs/symptoms of UTIs and with a clean-catch urine sample method. The NHS laboratories appeared to overdiagnose UTIs from nappy pad samples due to failure to distinguish contamination. The implications are that NHS laboratories may benefit from adopting the research laboratory's standardized methods, and clinicians should focus on obtaining higher-quality clean-catch urine samples for improved UTI diagnosis in young children.
Dr. Jean-Pierre Vaillancourt - Can You Keep High Path Avian Influenza from En...John Blue
Can You Keep High Path Avian Influenza from Entering Your Operation? - Dr. Jean-Pierre Vaillancourt, University of Montreal, Quebec, from the 2016 NIAA Annual Conference: From Farm to Table - Food System Biosecurity for Animal Agriculture, April 4-7, 2016, Kansas City, MO, USA.
More presentations at http://www.trufflemedia.com/agmedia/conference/2016_niaa_farm_table_food_system_biosecurity
Cleaning: It’s everyone’s responsibility. Review environmental cleaning procedures for all perioperative patient care areas (preoperative, OR, postoperative, and sterile processing). This information was originally shared in an AORN webinar, which is also available for free on demand at http://bit.ly/IHTNnp. One contact hour is available for the webinar through November 13, 2014. Learn more about AORN educational events at www.aorn.org/Events.
Research in pediatrician office - my story! NORC Aug 2019 New DelhiGaurav Gupta
Presented in NORC - Aug 2019 - National Original Research convention, discussion of Flu like illnesses and the Flu vaccination and drug utilization reviews and prescription audits and various other original research presented and published by Dr. Gaurav Gupta in his years of clinical practice, including yellow fever, Complementary medicines, drug costs and prescriptions analysis
Shine the Endoscopic Light on Oropharyngeal DysphagiaMichelleCimoli
Michelle Cimoli - DIG July 2017
Feel free to refer to the information contained in this presentation, but please acknowledge the original author, which is noted at the beginning of the presentation.
Bicycle Helmet Promotion in Children: What's the Evidence?Health Evidence™
Health Evidence - lead by Dr. Maureen Dobbins - hosted a webinar, funded by the Canadian Institutes of Health Research (KTB-112487), on bicycle helmet promotion interventions in children, presenting key messages, and implications for practice on Thursday October 25, 2012 at 1:00 pm EST.
This webinar interpreted the evidence in the following review:
Owen, R., Kendrick, D., Mulvaney, C., Coleman, T., Royal, S. (2011). Non-legislative interventions for the promotion of cycle helmet wearing by children. Cochrane Database of Systematic Reviews, 2011(11): Art. No.: CD003985.
This study aimed to identify pregnant women's perceptions of barriers to male involvement in antenatal care in Sekondi, Ghana. The study found that socio-demographic factors like partners' age, marital status, and living arrangement influenced perceptions. Socio-cultural factors like attitudes towards gender roles and masculinity also impacted perceptions. Health facility factors such as long wait times and distance to facilities were perceived as barriers. The study provides insight into women's views of barriers that could be addressed to increase male participation in antenatal care in Ghana.
Dr Deirdre Connolly , Trinity College Dublin (TCD)Investnet
Occupational therapy interventions for homecare clients in Dublin showed promising results in a pilot study. The interventions focused on improving functional abilities for daily activities. Quantitative measures found significant improvements in self-care and mobility scores after therapy. Qualitatively, clients reported gaining independence with activities like dressing, shopping, and social participation. Homecare hours were reduced for some clients, indicating potential cost savings. Larger studies are still needed, but initial findings suggest occupational therapy can benefit homecare clients' independence and quality of life.
An analysis of water quality and health data from a prospective study in peri-urban Zambia found that Enterococci counts in household drinking water, but not E. coli or total coliform counts, were positively associated with self-reported gastrointestinal illness among residents. Higher levels of Enterococci in water were linked to increased odds of gastrointestinal symptoms. While reported water treatment was initially associated with lower illness, this relationship did not remain significant after adjusting for other factors. The findings suggest Enterococci may be a better indicator than E. coli for predicting gastrointestinal disease risk from drinking water in this urban setting.
Enterococci but not E. coli counts in drinking water are positively associate...Michelo Simuyandi
Background and Objective
Studies of the association between faecal indicator bacteria and diarrhoeal disease risk have yielded mixed findings that range from no association to significant associations. We conducted a prospective study collecting repeated measures of water quality and health indicators and related covariates at household level in a peri-urban area south of Lusaka. The aim was to measure the association between the levels of Enterococci and E. coli in household drinking water and self-reported highly credible gastrointestinal illness (HCGI) experienced by household members in the previous seven days.
Methods
We carried out a prospective household based observational study of 290 households which involved household interviews, household observations and testing of household stored drinking water and source water for bacterial indicators of faecal contamination. Residents were interviewed regarding demographics, socio-economic status, drinking water access, treatment and storage, hygiene and sanitation practices, household-level environmental health related exposures, diarrhoea and other gastro-intestinal symptoms. The associations between Enterococci, E. coli, total coliforms in household drinking water and the HCGI experienced by household members were investigated using mixed-effects logistic regression.
Results
Univariate analyses showed Enterococci count was significantly associated with HCGI (OR 26.55 CI: 1.45, 486.04)for unadjusted and (OR 31.33 CI:(2.13, 461.73) for the adjusted. that Log2, but not E. coli or total coliforms,. For every doubling of enterococci count, the odds of HCGI increased by a factor of 1.54 (95% CI :( 1.13, 2.10), p=0.01). Reported treatment of household water (OR 0.41, p<0.01),><0.01) were negatively associated with HCGI, whilst having a place to wash hands near toilet was positively associated with HCGI outcomes (OR 2.12, p=0.03). A positive association of HCGI with age under 5 in the household did not reach statistical significance (OR 1.53, p=0.07.). In a multivariate model, log2 Enterococci count remained significantly associated with HCGI. A doubling of enterococci count increased the odds of HCGI by a factor of 1.67 (95% CI: 1.09, 2.56, p=0.02, after adjustment for water treatment.
Conclusion
In this urban setting, enterococci counts have a stronger association with HCGI than E.coli or total coliform count.
Enterococci but not E. coli counts in drinking water are positively associate...Michelo Simuyandi
Background and Objective
Studies of the association between faecal indicator bacteria and diarrhoeal disease risk have yielded mixed findings that range from no association to significant associations. We conducted a prospective study collecting repeated measures of water quality and health indicators and related covariates at household level in a peri-urban area south of Lusaka. The aim was to measure the association between the levels of Enterococci and E. coli in household drinking water and self-reported highly credible gastrointestinal illness (HCGI) experienced by household members in the previous seven days.
Methods
We carried out a prospective household based observational study of 290 households which involved household interviews, household observations and testing of household stored drinking water and source water for bacterial indicators of faecal contamination. Residents were interviewed regarding demographics, socio-economic status, drinking water access, treatment and storage, hygiene and sanitation practices, household-level environmental health related exposures, diarrhoea and other gastro-intestinal symptoms. The associations between Enterococci, E. coli, total coliforms in household drinking water and the HCGI experienced by household members were investigated using mixed-effects logistic regression.
Results
Univariate analyses showed Enterococci count was significantly associated with HCGI (OR 26.55 CI: 1.45, 486.04)for unadjusted and (OR 31.33 CI:(2.13, 461.73) for the adjusted. that Log2, but not E. coli or total coliforms,. For every doubling of enterococci count, the odds of HCGI increased by a factor of 1.54 (95% CI :( 1.13, 2.10), p=0.01). Reported treatment of household water (OR 0.41, p<0.01),><0.01) were negatively associated with HCGI, whilst having a place to wash hands near toilet was positively associated with HCGI outcomes (OR 2.12, p=0.03). A positive association of HCGI with age under 5 in the household did not reach statistical significance (OR 1.53, p=0.07.). In a multivariate model, log2 Enterococci count remained significantly associated with HCGI. A doubling of enterococci count increased the odds of HCGI by a factor of 1.67 (95% CI: 1.09, 2.56, p=0.02, after adjustment for water treatment.
Conclusion
In this urban setting, enterococci counts have a stronger association with HCGI than E.coli or total coliform count.
Status in terms of water and sanitation of some of the oldest refugee camp in Gaza.
The slides have not been converted properly. Some labels are superimposed and on top of others. Furthermore, most of them have got animations...it’s a pity since the whole presentation can’t be appreciated properly.
This document discusses the development and use of a rapid, non-invasive at-home HIV self-test called OraQuick. It describes:
1) The need for novel testing approaches to reach more individuals who have never been tested for HIV.
2) Details of the OraQuick test, including its accuracy (>99%), ease of use involving a oral fluid sample, and 30 month shelf life.
3) Clinical trial results showing the test had a 99.8% accuracy rate when used unsupervised and identified previously undiagnosed HIV-positive individuals, though some reported incorrect negative results.
4) Support resources like a 24/7 support center to help individuals interpret results and get linked to care
This document summarizes a community entry and diagnosis conducted in Emanyinya Sub-Location, Vihiga County. A team of students and supervisors assessed the health determinants and status of the community. They found that the majority of households had good ventilation but poor sanitation. Common diseases affecting adults and children included malaria, respiratory infections, and intestinal worms. While vaccination rates were high, nutrition and family planning posed challenges. The team recommended organizing medical camps and ensuring tutors are well-prepared to support students during community placements.
Similar to Impact of Shared Sanitation Facilities in Madhya Pradesh, India (2012) (20)
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central19various
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Kosmoderma Academy, a leading institution in the field of dermatology and aesthetics, offers comprehensive courses in cosmetology and trichology. Our specialized courses on PRP (Hair), DR+Growth Factor, GFC, and Qr678 are designed to equip practitioners with advanced skills and knowledge to excel in hair restoration and growth treatments.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
6. Background: Global Sanitation Trends
•Millennium Development Goals Sanitation Target: 75% covered with sustainable access to improved sanitation by 2015 1
•37% of the global population lacked access to improved sanitation 2
•15% of the global population practiced open defecation 2
•86% rural
1 WHO/UNICEF 2006, 2 WHO/UNICEF 2012
7. Sanitation in India
•66% of India lacked access to improved sanitation 1
•42% urban
•77% rural
•51% of India practiced open defecation 1
•14% urban
•67% rural
•Madhya Pradesh 2
•2006 - 27% households with toilets
•2010 - 54% households with toilets
1 WHO/UNICEF 2012, 2 WHO/UNICEF 2011
8. Sanitation Ladder - India
http://www.wssinfo.org/fileadmin/user_upload/resources/IND_san.pdf
= open defecation
= other unimproved facilities
= shared
= improved
URBAN
RURAL
TOTAL
9. Background: Shared Sanitation
•Shared sanitation definition
•In 2010, 11% of the global population utilized shared sanitation
•39% rural
•Shared sanitation in India: 9% in 2010
•19% urban
•4% rural
10. Background: Health Outcomes
•Research on shared sanitation is very limited:
•Alexandria, Egypt: infection with soil- transmitted helminthes 1
•Rural Tanzania: trachoma risk 2
•Dhaka, Bangladesh: parasite and diarrheal disease prevalence 3
•Botswana, Ghana, and Zambia: infection with intestinal parasites 4
•Bhopal, India: open defecation 5
•Urban Bangladesh: weight-for-height scores 6
1 Curtale, et. al., 1998 2 Montgomery, et. al., 2010 3 Khan, 1987
4 Feachem, et. al., 1983 5 Biran, et. al., 2011 6 WHO/UNICEF 2012
11. Objectives
•Describe sanitation access among households in Madhya Pradesh, India.
•Analyze the relationship between sanitation access and diarrheal disease prevalence, safety of female users, cleanliness, and user satisfaction.
•Recommend changes to the current definition of improved sanitation based on research results.
12. Methods
•World Bank Water and Sanitation Program
Global Scaling Up Rural Sanitation intervention
•2009 baseline survey
•Cross-sectional study of Impact Evaluation survey:
•Household questionnaire
•Children < 5 years health questionnaire
13. Methods
•Sanitation facility characteristics
•Sanitation status
•Sharing status
•Health outcome
•Two-week prevalence of diarrheal disease
•3 or more bowel movements per day
•Cleanliness outcome
•Presence of flies
14. Methods
•Female safety outcomes
•Safety of sanitation facility during the day
•Safety of sanitation facility during the night
•Privacy
•Satisfaction with sanitation facility
•Potential confounders
15. Data Analysis
•Descriptive statistics
•Pearson’s Chi-square tests for association among sanitation variables and health, safety, and cleanliness outcomes
•Logistic regression analysis
•Proportional Odds Model
16. Descriptive Statistics
Madhya Pradesh
n (%)
Survey data
Households
1,978
Children
3,464
Sanitation status
Improved
261 (14.1%)
Unimproved
1,856 (85.9%)
Sharing status
Not shared
253 (12.8%)
Shared
1,717 (87.2%)
Health Outcome
Two-week diarrheal disease
prevalence
510 (14.7%)
17. Madhya Pradesh
n (%)
Female safety
Daytime
968 (49.0%)
Nighttime
452 (22.9%)
Privacy
542 (27.5%)
Cleanliness – presence of flies
Always
1,671 (84.5%)
Sometimes
201 (10.2%)
Rarely
104 (5.3%)
Satisfaction
Satisfied
774 (39.3%)
Not satisfied
1,193 (60.7%)
18. Child Health Results
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Shared
Shared (v. not shared)
1.534
0.765, 3.074
Location
Household latrine/ less than 10 min. (v. no designated area)
1.328
0.761, 2.319
Location
More than 10 min. (v. no designated area)
1.408
1.032, 1.921*
Visible feces
One or more (v. none)
0.522
0.353, 0.773*
Feces odor
Yes (v. no)
1.264
0.857, 1.864
Logistic regression for two-week diarrheal
disease prevalence among children
*Statistically significant at p < 0.05
19. Safety Results
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Sanitation status
Improved (v. unimproved)
14.921
3.695, 60.247*
Sharing status
Not shared (v. shared)
3.119
1.016, 9.573*
Toilet location
Household latrine/ less than 10 min. (v. no designated area)
0.927
0.511, 1.684
Logistic regression for female safety – daytime
*Statistically significant at p < 0.05
20. Safety Results
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Sanitation status
Improved (v. unimproved)
30.438
7.388, 125.409*
Sharing status
Not shared (v. shared)
1.830
0.581, 5.767
Toilet location
Household latrine/ less than 10 min. (v. no designated area)
5.663
2.778, 11.546*
Toilet location
More than 10 min. (v. no designated area)
1.995
1.233, 3.228*
Logistic regression for female safety – nighttime
*Statistically significant at p < 0.05
21. Safety Results
*Statistically significant at p < 0.05
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Sanitation status
Improved (v. unimproved)
15.824
4.874, 51.379*
Sharing status
Not shared (v. shared)
3.981
1.468, 10.796*
Toilet location
Household latrine/ less than 10 min. (v. no designated area)
3.892
2.008, 7.545*
Toilet location
More than 10 min. (v. no designated area)
1.955
1.315, 2.907*
Logistic regression for female privacy
22. Cleanliness Results
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Sanitation status
Improved (v. unimproved)
5.221
1.963, 13.883*
Sharing status
Not shared (v. shared)
2.449
1.036, 5.790*
Toilet location
Household latrine/ less than 10 min. (v. no designated area)
6.248
2.588, 15.086*
Toilet location
More than 10 min. (v. no area)
1.992
1.014, 3.911*
Visible feces
None (v. one or more)
1.286
0.719, 2.302
Feces odor
No (v. yes)
0.693
0.385, 1.246
Open pit/ open drain nearby
No (v. yes)
1.269
0.823, 1.958
*Statistically significant at p < 0.05
Proportional Odds Model for presence of flies
23. Satisfaction Results
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Sanitation status
Improved (v. unimproved)
1.085
0.270, 4.353
Sharing status
Not shared (v. shared)
9.897
2.713, 36.097*
Presence of flies
Rarely (v. always)
1.931
0.559, 6.673
Presence of flies
Sometimes (v. always)
0.721
0.362, 1.436
Toilet location
Household latrine/ less than 10 min. (v. no designated area)
0.662
0.326, 1.346
Toilet location
More than 10 min. (v. no designated area)
0.381
0.271, 0.536*
Logistic regression for satisfaction
*Statistically significant at p < 0.05
24. Satisfaction Results
Variable
Outcome modeled
Odds Ratio
95% Confidence Interval
Feces odor
No (v. yes)
1.094
0.674, 1.775
Open pit/ open drain nearby
No (v. yes)
0.541
0.386, 0.757*
Visible feces
None (v. one or more)
0.496
0.298, 0.827*
Female safety – day
Yes (v. no)
6.489
4.539, 9.276*
Female safety – night
Yes (v. no)
1.496
0.940, 2.382
Female privacy
Yes (v. no)
1.397
0.903, 2.163
Logistic regression for satisfaction
*Statistically significant at p < 0.05
27. Strengths
•Large dataset
•One of first studies to analyze shared sanitation and user satisfaction
28. Discussion
•Number of households sharing
•How shared facilities affect user satisfaction
•Analysis of household survey data from Bangladesh, Tanzania, and Indonesia
29. Acknowledgments
•Dr. Angelo Elmi
Dept. of Epidemiology and Biostatistics
•Dr. Jay Graham
Dept. of Environmental and Occupational Health
•Craig Kullmann
World Bank Water and Sanitation Program
•Prof. Ann Goldman
Dept. of Epidemiology and Biostatistics