The document summarizes a presentation on the neurobiology of regulation and resiliency given by Sophia Deborah Erez. It discusses how the triune brain, autonomic nervous system, and trauma can impact affect regulation. Specifically, it describes how trauma can cause the nervous system to become dysregulated and stuck in hyper-arousal or hypo-arousal states outside the optimal window of tolerance. The presentation emphasizes how developing self-regulation and expanding one's window of tolerance through trauma therapy can promote more resilient affect regulation.