Hybridoma Technology ( Production , Purification , and Application )
CINAHL AND PUBMED SEARCH STRATEGIES
1. CINAHL AND PUBMED
SEARCHING
JULIE SARPY, PHD, MSLS, MA
REFERENCE & INSTRUCTION LIBRARIAN
LIAISON TO THE DR. KIRAN C. PATEL COLLEGES OF ALLOPATHIC
MEDICINE AND OSTEOPATHIC MEDICINE
jsarpy@nova.edu
954-262-3121
954-262 –3106 (main)
hpdref@nova.ed
2. OBJECTIVES
• REVIEW OF KINDS OF RESEARCH
• UNDERSTAND VARIOUS FEATURES OF PUBMED & CINAHL AND GET PRACTICE USING
THEM.
• THE FEATURES OF THE SEARCH PAGES
• STRUCTURE A SEARCH WITH A PICO QUESTION
• CONDUCT AN ADVANCED SEARCH USING CONTROLLED VOCABULARY (MESH SUBJECT
HEADINGS, CINAHL SUBJECT HEADINGS) AND BOOLEAN OPERATORS (AND, OR, NOT)
• COMBINING YOUR SEARCH CONCEPTS USING SEARCH HISTORY
• REFINING YOUR SEARCH WITH LIMITS
• CHECKING FOR PEER REVIEW
3. IS IT RESEARCH?
• READ THE ABSTRACT FIRST BEFORE TRACKING DOWN FULL TEXT
• IS IT WRITTEN BY THE PEOPLE WHO DID THE RESEARCH?
• WHEN REVIEWING ARTICLE LOOK FOR:
*Background or Lit Review
*Methods
*Results
*Conclusions
*Discussion
5. SO WHERE DO
YOU FIND IT?
NOVA.EDU/HPDLIBRARY
*MEDLINE –
*COMPILED BY THE NATIONAL LIBRARY OF
MEDICINE
*A DATABASE –NOT AN INTERFACE
*PUBMED IS - FREE, GOV’T FUNDED,
CITATIONS ONLY –NSU PROVIDES LINKS TO
FULL TEXT
*NSU OFFERS OTHER INTERFACES FOR
SEARCHING MEDLINE -OVID, EBSCO,
PROQUEST. . .
7. The PICO(T) framework is a consistent
"formula" for developing literature search
strategies. PICO(T) stands for:
P = Population/Patient (you intend to study)
I = Intervention (drug/therapy that is
intervening)
C = Comparison/Control (intervention with
another drug, therapy, or placebo)
O = Outcome (did the intervention provide
relief)
(T) (optional) Time element or Type of Study
When you put all 4 ideas into one clinical
PICO Format
8. PICO EXAMPLE 1:
What are the adverse effects in infants who receive
the chickenpox vaccine?
The Population to be studied is infant;
the Intervention is the vaccine; the Comparison to be
studied are infants who do not receive the vaccine;
and the Outcome to be studied is the adverse effects
in those vaccinated.
9. PICO EXAMPLE 2:
For patients with type II diabetes, do routine
eye exams reduce the occurrence of
blindness?
The Population is patients with type II
diabetes. The Intervention is routine eye
exams. There is no Comparison. The
Outcome is reduced incidence of blindness.
12. BOOLEAN OPERATORS
AND
NARROW SEARCH RESULTS
ALL SEARCH TERMS MUST
BE PRESENT IN RESULTS
OR
BROADEN YOUR RESULTS
ANY OF YOUR SEARCH
TERMS CAN BE PRESENT IN
THE RESULTING RECORDS
NOT
EXCLUDE WORDS FROM
YOUR SEARCH
NARROW YOUR SEARCH
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13.
14.
15.
16.
17. Are flu vaccines safe for people
with egg allergies?
P-people with egg allergies
I-flu vaccines
C-n/a
O-safety
Using MeSH Headings in PubMed
21. In elderly patients with high blood pressure, are ACE
inhibitors more effective than beta blockers in controlling
blood pressure and minimizing adverse effects?
P -elderly patients with high blood pressure
I -ACE inhibitors
C -beta blockers
O -controlling blood pressure
Using MeSH Headings in PubMed
25. MORE EXAMPLES
•Diabetes and the effects of long term effects of insulin
•Mesenchymal Stem Cell Therapy as Alternative Treatment
for Articular Cartilage Repair
•Treatment of Trichotillomania (hair pulling): Pharmacotherapy vs Psy
28. CINAHL HEADINGS
MESH HEADINGS WITH SOME MODIFICATIONS TO MAKE THEM MORE APPLICABLE
TO OTHER FIELDS OF HEALTH CARE –USE THEM THE SAME WAY
29. CINAHL SEARCHING
• “RECENT ARTICLES ON HEART ATTACKS AND ASPIRIN USE IN MIDDLE AGED
WOMEN.”
• USE SUBJECT HEADINGS
• COMBINE SETS WITH AND
• USE AGE AND SEX FILTERS
34. ORGANIZE YOUR SEARCH STRATEGY USING PICO OR ANOTHER
METHOD
USE MESH & CINAHL HEADINGS TO TAKE ADVANTAGE OF SUBJECT
EXPERTS CATALOGING USING CONTROLLED VOCABULARY
USE SUBHEADINGS, LIMIT TO MAIN TOPIC, FOR PRECISION
BUILD A SEARCH STEP-BY-STEP,
COMBINE THEM WITH BOOLEAN OPERATORS
USE LIMITS TO FURTHER REFINE RESULTS
Review
35. Julie Sarpy, PhD, MSLS, MA
Reference Support Librarian
Liaison to the Colleges of
Allopathic and Dental Medicine
jsarpy@nova.edu
954-262-3121
hpdref@nova.edu - goes to all
the reference librarians
(954) 262 – 3106 (main)