revascularisation
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This document summarizes regenerative endodontic procedures. It discusses the history of revascularization and defines related terms. The principle that dental pulp has the ability to self-revascularize after trauma or infection is explained. The typical two-appointment procedure is outlined, including disinfection in the first appointment and inducing bleeding in the second. The mechanisms of early cell mobilization and late cell differentiation are described. Limitations and a case report demonstrating apical closure after 6 months are provided. Recent concepts and references on the topic are listed at the end.
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Regenerative endodontics
REGENERATIVE ENDODONTICS CONSISTS OF INTRODUCTION, HISTORY, DEFINITION OF REGENERATION, TISSUE ENGINEERING, SCAFFOLD,, REVASCULARIZATION, REVITALIZATION, PROCEDURES FOR REGENERATION STEM CELLS, SOURCES OF STEM CELLS,DENTAL PULP STEM CELLS, stem cells from human exfoliated deciduous teeth
Regenerative endodontics
This document provides an overview of regenerative endodontics, which aims to regenerate dental tissues through biologically-based procedures using stem cells, growth factors, and scaffolds. Key elements for pulp regeneration include reliable stem cell sources, such as dental pulp stem cells, growth factors to stimulate cell proliferation and differentiation, and appropriate scaffolds. Potential regenerative therapies include revascularization, stem cell therapy, scaffold implantation, and gene delivery. Measuring clinical outcomes and further applications are areas of future focus to develop regenerative endodontic therapies.
Regenerative endodontics & Revascularization
This document discusses revascularization/regeneration procedures performed on immature molars. It defines regenerative endodontics as biologically based procedures to replace damaged pulp and root structures. The objectives of regenerative endodontics are to regenerate pulp-like tissue, dentin, and root structures. Stem cells, scaffolds, and growth factors are key elements in dental tissue engineering and regeneration procedures. The document also discusses the use of triantibiotic pastes containing ciprofloxacin, metronidazole, and minocycline to disinfect immature teeth and enable revascularization.
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Regenerative endodontics aims to regenerate damaged pulp and root structures through biologically-based procedures. Historically, studies in the 1960s-70s showed blood clots could induce tissue formation in root canals. Current methods include placing stem cells on scaffolds with growth factors in the root canal to regenerate the pulp-dentin complex. Triple antibiotic paste, calcium hydroxide, and MTA are used as antimicrobial medicaments. The protocol involves inducing bleeding into the root canal to form a blood clot which triggers regeneration. The goal is periradicular health and evidence of vital regenerated tissue through radiographic and clinical measures.
APEXOGENESIS AND APEXIFICATION.pptx
Apexogenesis aims to preserve the vital pulp tissue in an immature tooth to allow continued root development. It involves a deep pulpotomy to remove inflamed tissue while maintaining healthy tissue. Apexification induces formation of a calcified barrier at an open apex in a nonvital immature tooth. Calcium hydroxide is typically used over multiple visits but MTA can induce barrier formation in a single visit. The goal is to create an artificial barrier against which root filling can be condensed to allow restoration of the immature tooth.
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This document provides an overview of regenerative endodontics. It defines regenerative endodontics as the creation and delivery of tissues to replace diseased, missing, and traumatized pulp. The document discusses the history and technologies of regenerative endodontics, including the use of stem cells, growth factors, and scaffolds. The key goals of regenerative endodontics are outlined as regenerating pulp-dentin complex tissue and revitalizing teeth through pulp regeneration.
Revascularisation
This document discusses revascularization procedures for immature permanent teeth with necrotic pulps. It begins by introducing the challenges of treating such teeth and the potential for revascularization to encourage continued root development. The history of revascularization is then reviewed, from early case studies in the 1960s demonstrating new tissue formation in root canals, to more recent definitions and understanding of the process. Key aspects of revascularization techniques using calcium hydroxide, triple antibiotic paste, and their two-step protocols are then outlined. Considerations for instrumentation, irrigation, and medication of the root canal are also presented.
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Regenerative endodontics
REGENERATIVE ENDODONTICS CONSISTS OF INTRODUCTION, HISTORY, DEFINITION OF REGENERATION, TISSUE ENGINEERING, SCAFFOLD,, REVASCULARIZATION, REVITALIZATION, PROCEDURES FOR REGENERATION STEM CELLS, SOURCES OF STEM CELLS,DENTAL PULP STEM CELLS, stem cells from human exfoliated deciduous teeth
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This document provides an overview of regenerative endodontics, which aims to regenerate dental tissues through biologically-based procedures using stem cells, growth factors, and scaffolds. Key elements for pulp regeneration include reliable stem cell sources, such as dental pulp stem cells, growth factors to stimulate cell proliferation and differentiation, and appropriate scaffolds. Potential regenerative therapies include revascularization, stem cell therapy, scaffold implantation, and gene delivery. Measuring clinical outcomes and further applications are areas of future focus to develop regenerative endodontic therapies.
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This document discusses revascularization/regeneration procedures performed on immature molars. It defines regenerative endodontics as biologically based procedures to replace damaged pulp and root structures. The objectives of regenerative endodontics are to regenerate pulp-like tissue, dentin, and root structures. Stem cells, scaffolds, and growth factors are key elements in dental tissue engineering and regeneration procedures. The document also discusses the use of triantibiotic pastes containing ciprofloxacin, metronidazole, and minocycline to disinfect immature teeth and enable revascularization.
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Regenerative endodontics aims to regenerate damaged pulp and root structures through biologically-based procedures. Historically, studies in the 1960s-70s showed blood clots could induce tissue formation in root canals. Current methods include placing stem cells on scaffolds with growth factors in the root canal to regenerate the pulp-dentin complex. Triple antibiotic paste, calcium hydroxide, and MTA are used as antimicrobial medicaments. The protocol involves inducing bleeding into the root canal to form a blood clot which triggers regeneration. The goal is periradicular health and evidence of vital regenerated tissue through radiographic and clinical measures.
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Apexogenesis aims to preserve the vital pulp tissue in an immature tooth to allow continued root development. It involves a deep pulpotomy to remove inflamed tissue while maintaining healthy tissue. Apexification induces formation of a calcified barrier at an open apex in a nonvital immature tooth. Calcium hydroxide is typically used over multiple visits but MTA can induce barrier formation in a single visit. The goal is to create an artificial barrier against which root filling can be condensed to allow restoration of the immature tooth.
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This document discusses revascularization procedures for immature permanent teeth with necrotic pulps. It begins by introducing the challenges of treating such teeth and the potential for revascularization to encourage continued root development. The history of revascularization is then reviewed, from early case studies in the 1960s demonstrating new tissue formation in root canals, to more recent definitions and understanding of the process. Key aspects of revascularization techniques using calcium hydroxide, triple antibiotic paste, and their two-step protocols are then outlined. Considerations for instrumentation, irrigation, and medication of the root canal are also presented.
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This document provides an overview of regenerative endodontics and tissue engineering. It discusses definitions of key terms like regeneration, repair, and the regenerative triad of stem cells, growth factors, and scaffolds. The history and objectives of regenerative endodontics are described. Regenerative endodontic procedures aim to physiologically replace damaged tooth structures using principles of tissue engineering. This involves stimulating regeneration of the pulp-dentin complex using the building blocks of stem cells, signaling molecules, and matrices.
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This document discusses the procedure of pulp revascularization to treat immature permanent teeth with necrotic pulps and open apices. It involves disinfecting the root canal with calcium hydroxide or triple antibiotic paste, inducing bleeding into the canal to form a blood clot, and placing MTA over the clot to allow new tissue and blood vessel formation. This results in continued root development, thickening of dentin walls, and closure of the root apex. Advantages include natural root maturation and vital tooth structure, while disadvantages can include discoloration or resistant bacterial infection.
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Evaluation of obturation
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Silver cone
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Evolution
Chemistry
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Standardized Points:
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Dr. Tinet Mary Augustine presents information on regenerative endodontics, including its history, goals, mechanisms, and a case study. Regenerative endodontics aims to revascularize and regenerate dental pulp through disinfection and inducing bleeding to transport stem cells. The procedure involves chemically debriding the root canal, inducing bleeding to introduce stem cells, and sealing with MTA or biodentin. Over 6 months, the case study showed resolution of an apical radiolucency and root lengthening, indicating regeneration of the pulp-dentin complex. Long-term follow-up of 1-3 years is recommended to monitor regeneration.
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Mid treatment flare ups in endodontic
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Introduction
Objectives
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3 Main Functions
Factors Influencing Leakage
Gp : Sealer Ratio
Def:obturate And Obturation Technique
Importance Of Effectively Sealing The Rc System
Historical Perspectives
Timing Of Obturation
Preparation For Obturation
Monoblock Concept
Apical Extent Of Obturation
Underfilling & Underextension
Overfilling Vs Overextension
Evaluation of obturation
Radiographic evaluation
Clinical evaluation
Methods of microleakage evaluation
Obturating materials
Ideal requirements
Earlier root canal filling materials
Silver cone
Gutta Percha
Evolution
Chemistry
Dental GP composition
Phases
Phase transformation
Properties
Commercial Manufacture
Coagulation
Obach’s Technique
Current Forms
Solid Core Gutta Percha Points:
Standardized Points:
Non Standardized Points
Thermoplasticized Gutta Percha:
Chemically Plastisized Gp
Immuno Cross Reactivity
Disinfection
Disinfecting Agents
Other newer obturating materials
Resilon
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Primer:
Resilon sealer (epiphany)
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Endorez
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Medicated gp
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This document discusses endodontic retreatment. It defines retreatment as removing root canal filling materials from a tooth to clean, shape, and re-obturate the canals. Reasons for retreatment include persistent or reinroduced intraradicular microorganisms, extraradicular infection, foreign body reaction, or true cysts. Evaluation involves clinical examination, radiographs, and assessing for symptoms like pain, swelling or sinus tracts. Success is defined as resolution of symptoms and periapical radiolucency, while failure is persistence or worsening of these signs.
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The presentation features the pulp reparative and regenerative procedures which can be carried out in immature teeth. It involves development of mature tooth from an immature one by root formation and root fixation as a preparatory phase for root canal treatment.
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This document discusses the history, physics, and applications of ultrasonics and sonics in endodontics. It begins with definitions of key terms like ultrasound, ultrasonic instrumentation, and endosonics. It then covers the physics behind ultrasonics and sonics, including how piezoelectric and magnetostrictive transducers work. Biophysical effects like cavitation and acoustic streaming are also discussed. The document concludes by outlining various ultrasonic tips categorized by approach (surgical vs nonsurgical) and use (access, removal, etc.), and applications in endodontic procedures.
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This document discusses various aspects of vital pulp therapy (VPT), including indirect pulp capping (IPC), direct pulp capping (DPC), and pulpotomy procedures. It provides the history and objectives of these procedures, as well as guidelines for when each is appropriate based on factors like the size of a pulp exposure and presence of symptoms. Materials commonly used for VPT are also reviewed, including calcium hydroxide, MTA, and others. Success rates from studies on IPC and factors influencing the outcome of VPT are presented.
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revascularisation
- 1. Dr Vijai S Reader Dept of Pedodontics Malabar dental college
- 3. INTRODUCTION Moores CF et al ,1963,1969,1981
- 4. HISTORY Revascularization (Iwaya 2001) Regenerative endodontic procedure (Hargreaves 2008,AAE 2007) Guided tissue regeneration (Anibal Diogenes2017) Revitalization (Lenzi and Trope,Torabinejad 2011,Wang 2010,ESF2016) Maturogenesis (Weisleder 2003,Aggarwal V 2012 )
- 6. PRINCIPLE Dental pulp has the capacity to repair and successfully self-revascularize after infection or trauma. Anibal Diogenes, Dds, Ms, Phd, Nikita B. Ruparel, Ms, Dds, Phd: Regenerative Endodontic Procedures: Clinical Outcomes. Dent Clin N Am 61 (2017) 111–125
- 7. PROCEDURE FIRST APPONTMENT • Objective:disinfection • Technique:chemical debridement • Irrigant:0.5% NAOCL,17% EDTA,saline • Antimicrobial:TAP,CAOH SECOND APPOINTMENT • Objective:Transport stem cells into disinfected canal system • Technique:induced bleeding • Irrigant:17% EDTA • Capping:MTA/Biodentin Lin LM, Kahler B. A review of regenerative endodontics: current protocols and future directions. J Istanb Univ Fac Dent 2017;51(3 Suppl 1):S41-S51.
- 8. MECHANISM Anibal Diogenes, Nikita B. Ruparel, Regenerative Endodontic Procedures: Clinical Outcomes:Dent Clin N Am 61 (2017) 111–125
- 10. LIMITATION Sahng G. Kim, Biological Molecules for the Regeneration of the Pulp-Dentin Complex, Dent Clin N Am 61 (2017) 127–141
- 12. CASE REPORT TOOTH-11 21 ELLIS # 4 • Pre op • Pre op X-ray(stage 3)
- 14. REVIEW AFTER 6 MONTHS • Pre op • 6 months review APICAL CLOSURE
- 15. • Root closure • Composite restoration
- 16. REVIEW PERIOD REVIEW PROTOCOL EXPECTED OUTCOME • Resolution of apical radiolucency(6-12 months) • Root lengthening by 6months • Root thickening within 12-24 months • Asymptomatic nature • Regaining of pulp vitality Lin LM, Kahler B. A review of regenerative endodontics: current protocols and future directions. J Istanb Univ Fac Dent 2017;51(3 Suppl 1):S41-S51. • For 1year -3months follow up • After that 6month follow up
- 17. RECENT CONCEPTS • Release profile • Scaffold functionalization • Core/shell microsphere • Cell homing approach Sahng G. Kim, Biological Molecules for the Regeneration of the Pulp-Dentin Complex, Dent Clin N Am 61 (2017) 127–141
- 18. REFERENCES • Anibal Diogenes, Nikita B. Ruparel: Regenerative Endodontic Procedures: Clinical Outcomes. Dent Clin N Am 61 (2017) 111–125 • Lin LM, Kahler B. A review of regenerative endodontics: current protocols and future directions. J Istanb Univ Fac Dent 2017;51(3 Suppl 1):S41-S51. • Sahng G. Kim, Biological Molecules for the Regeneration of the Pulp-Dentin Complex, Dent Clin N Am 61 (2017) 127– 141 • Kim SG, Malek M, Sigurdsson A, Lin LM, Kahler B. Regenerative endodontics: a comprehensive review. International Endodontic Journal, 51, 1367–1388, 2018.
- 19. CLEAR THE PATH FOR THE NATURE TO HEAL THANK YOU