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DR.TINET MARY AUGUSTINE.MDS 1
Dr.Tinet Mary Augustine. BDS,MDS
Pediatric Dentist
Dr.Tinet’s Pedorayz, Pediatric And Early Age Orthodontic Dental Clinic
REGENERATIVE ENDODONTICS
BASICS AND CASE REPORT
DR.TINET MARY AUGUSTINE.MDS 2
WHAT IS
REVASCULARISATION?
DR.TINET MARY AUGUSTINE.MDS 3
HISTORY
NOMENCLATURE
Revascularization
(Iwaya 2001)
Regenerative
endodontic procedure
(AAE 2007)
Guided tissue regeneration
(Anibal Diogenes2017)
Revitalization
(Torabinejad 2011,Wang
2010,ESF2016)
Maturogenesis
(Aggarwal V 2012 )
DR.TINET MARY AUGUSTINE.MDS 4
IMPORTANCE IN PEDIATRIC
DENTISTRY
DR.TINET MARY AUGUSTINE.MDS 5
REVASCULARIZATION
VS
REGENERATION
• Self revascularization concept after severe
trauma(Kling M Cvek M 1986)
• Supported by Anderson in series of study in
1995,and 1996
DR.TINET MARY AUGUSTINE.MDS 6
OBJECTIVE
Dental pulp has the capacity to repair and
successfully self-revascularize after infection or
trauma.
Anibal Diogenes, Dds, Ms, Phd, Nikita B. Ruparel, Ms, Dds, Phd: Regenerative Endodontic
Procedures: Clinical Outcomes. Dent Clin N Am 61 (2017) 111–125
DR.TINET MARY AUGUSTINE.MDS 7
PROCEDURE
FIRST APPONTMENT
• Objective:disinfection
• Technique:chemical
debridement
• Irrigant:0.5%
NAOCL,17% EDTA,saline
• Antimicrobial:TAP,CAOH
SECOND APPOINTMENT
• Objective:Transport stem
cells into disinfected canal
system
• Technique:induced
bleeding
• Irrigant:17% EDTA
• Capping:MTA/Biodentin
Lin LM, Kahler B. A review of regenerative endodontics: current protocols and future
directions. J Istanb Univ Fac Dent 2017;51(3 Suppl 1):S41-S51.DR.TINET MARY AUGUSTINE.MDS 8
MECHANISM
Anibal Diogenes, Nikita B. Ruparel, Regenerative Endodontic Procedures: Clinical
Outcomes:Dent Clin N Am 61 (2017) 111–125
DR.TINET MARY AUGUSTINE.MDS 9
Early
Cell
mobilization
Late
Cell
differentiation
Scaffolds
Collagen
matrix
Microsphere
Shell
microsphere DR.TINET MARY AUGUSTINE.MDS 10
GOALS OF REGENERATIVE
ENDODONTIC PROCEDURE
DR.TINET MARY AUGUSTINE.MDS 11
LIMITATION
Sahng G. Kim, Biological Molecules for the Regeneration of the Pulp-Dentin Complex, Dent
Clin N Am 61 (2017) 127–141
DR.TINET MARY AUGUSTINE.MDS 12
PROCEDURE
PRE OP
DEBRIDEMENT
WORKING LENGTH DETERMINATION
IRRIGATION USING 1.5% NAOCL
METAPEX DRESSING GIVEN
DR.TINET MARY AUGUSTINE.MDS 13
CASE REPORT
TOOTH-11 21
ELLIS # 4
• Pre op
• Pre op xray
DR.TINET MARY AUGUSTINE.MDS 14
REVIEW AFTER 6 MONTHS
• Pre op • 6 months review
APICAL CLOSURE
DR.TINET MARY AUGUSTINE.MDS 15
• Root closure • Composite restoration
DR.TINET MARY AUGUSTINE.MDS 16
REVIEW PERIOD
REVIEW PROTOCOL EXPECTED OUTCOME
• Resolution of apical
radiolucency(6-12
months)
• Root lengthening by
6months
• Root thickening within
12-24 months
• Asymptomatic nature
• Regaining of pulp vitality
Lin LM, Kahler B. A review of regenerative endodontics: current protocols and future
directions. J Istanb Univ Fac Dent 2017;51(3 Suppl 1):S41-S51.
• For 1year -3months
follow up
• After that 6month
follow up
DR.TINET MARY AUGUSTINE.MDS 17
REFERENCES
• Anibal Diogenes, Dds, Ms, Phd, Nikita B. Ruparel, Ms, Dds,
Phd: Regenerative Endodontic Procedures: Clinical
Outcomes. Dent Clin N Am 61 (2017) 111–125
• Lin LM, Kahler B. A review of regenerative endodontics:
current protocols and future directions. J Istanb Univ Fac
Dent 2017;51(3 Suppl 1):S41-S51.
• Sahng G. Kim, Biological Molecules for the Regeneration of
the Pulp-Dentin Complex, Dent Clin N Am 61 (2017) 127–
141
DR.TINET MARY AUGUSTINE.MDS 18
CLEAR THE PATH FOR THE NATURE
TO HEAL
THANK YOUDR.TINET MARY AUGUSTINE.MDS 19

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