This document discusses research problems in nursing research. It defines a research problem as a topic that a researcher wants to investigate or study. Research problems come from various sources like nursing practice, literature reviews, theories, and consultation with experts. When selecting a research problem, internal criteria like the researcher's interests and competency and external criteria like the significance, researchability, novelty, urgency, and feasibility of the problem are considered. The research problem is then formulated into a researchable question through a process of narrowing the scope. The components of a well-formulated research problem statement follow the PICOT format of Population, Intervention, Comparison group, Outcome of interest, and Time.