The document reports on the inaugural national symposium of the Indonesia One Health University Network (INDOHUN) held in May 2012, focusing on enhancing collaboration among universities and health sectors to implement a One Health approach in Indonesia. The symposium aimed to set missions for Indonesian universities related to disease outbreak response and develop a strategic plan for INDOHUN's future activities, bringing together diverse stakeholders from academia and health-related organizations. Participants discussed objectives and core competencies essential for integrating the One Health approach across various disciplines to improve overall health systems in Indonesia.