Plantar fasciitis is a painful and debilitating condition. It primarily affects athletes, people whose jobs require them to stand for long periods of time. And those who put heavy stress on their feet. It involves inflammation of the plantar fascia, the strands of connective tissue that run along the sole of the foot, linking the heel of the foot to the ball and toes.
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Hand dominance is the preferential use of one hand over the other for motor tasks.
90% of people are right-hand dominant, and the majority of injuries (acute and cumulative trauma) occur to the dominant limb, creating a double-impact injury whereby a person is left in a functional state of single-handedness and must rely on the less dexterous, non-dominant hand.
When loss of dominant hand function is permanent, a forced shift of dominance is termed injury-induced hand dominance transfer
There are innate differences in dexterity influenced by hand dominance.
Although most activities are accomplished bimanually, the dominant hand acts as the more dexterous, main executor while the non-dominant hand acts as supporter.
In the context of rehabilitation, permanent loss of dexterity in dominant hand is more devastating because dexterity skill previously endowed to dominant hand must be transferred to non-dominant hand
Persons with unilateral dexterity loss of the dominant limb have two challenges
they are forced to complete two handed tasks with one hand.
the remaining limb, which primarily functioned as the supporting limb, must assume dexterity responsibilities of the dominant limb.
Hand dominance is therefore a critical factor related to rehabilitation addressing dexterity of persons with upper limb injuries.
Persons with unilateral dexterity loss of the dominant limb have two challenges
they are forced to complete two handed tasks with one hand.
the remaining limb, which primarily functioned as the supporting limb, must assume dexterity responsibilities of the dominant limb.
Hand dominance is therefore a critical factor related to rehabilitation addressing dexterity of persons with upper limb injuries.
Persons with unilateral dexterity loss of the dominant limb have two challenges
they are forced to complete two handed tasks with one hand.
the remaining limb, which primarily functioned as the supporting limb, must assume dexterity responsibilities of the dominant limb.
Hand dominance is therefore a critical factor related to rehabilitation addressing dexterity of persons with upper limb injuries.
Leading cause of upper limb amputations is trauma occurring in males ages 15-25 years,
Most of traumatic amputation happen on dominant limb
vascular complications of diseases.
No limb prefernces
cancer/tumors (common cause of more proximal amputations such as a shoulder disarticulation or forequarter amputation)
Alternative treatment for rotator cuff tear or injurypallaviparmar9
Medica Stem Cells offers effective alternative treatment for rotator cuff tear or injury with a faster recovery time compared to conventional treatments.
Everything you need to know about stem cells.pptxpallaviparmar9
Adult stem cells (also known as Somatic stem cells) are undifferentiated cells found throughout your body.
In some adult tissues, such as bone marrow, muscle, and brain, discrete populations of adult stem cells generate replacements for other cells that are lost through normal wear and tear, injury, or disease.
Stem Cell Therapy 9 Things You Need to Know by Dr. David Greene of R3 Stem Ce...R3 Stem Cell
In this powerful presentation, Dr. David Greene R3 Stem Cell shares his revolutionary stem cell therapy and how it can help you. With no surgery or medication required, R3 exosome therapy is an innovative regenerative medicine therapy that uses a patient’s cells to treat various conditions, such as heart disease, diabetes, and cancer.
India's one of the first dedicated to practicing Prolotherapy (Regenerative Injection Therapy) in an orthopedic clinical setting. We the Prolotherapy Clinic are the premier destination for cutting-edge interventional (minimally invasive) Regenerative Orthopedics and Sports Medicine.
A spinal fusion surgery is a procedure that is used to join two or more vertebrae together. Spinal Fusion Surgery India has a high success rate and you can be one of the many people who recover from a serious illness and live a long and happy life.
Rehabilitation of dominant upper limb amputationJoe Antony
Hand dominance is the preferential use of one hand over the other for motor tasks.
90% of people are right-hand dominant, and the majority of injuries (acute and cumulative trauma) occur to the dominant limb, creating a double-impact injury whereby a person is left in a functional state of single-handedness and must rely on the less dexterous, non-dominant hand.
When loss of dominant hand function is permanent, a forced shift of dominance is termed injury-induced hand dominance transfer
There are innate differences in dexterity influenced by hand dominance.
Although most activities are accomplished bimanually, the dominant hand acts as the more dexterous, main executor while the non-dominant hand acts as supporter.
In the context of rehabilitation, permanent loss of dexterity in dominant hand is more devastating because dexterity skill previously endowed to dominant hand must be transferred to non-dominant hand
Persons with unilateral dexterity loss of the dominant limb have two challenges
they are forced to complete two handed tasks with one hand.
the remaining limb, which primarily functioned as the supporting limb, must assume dexterity responsibilities of the dominant limb.
Hand dominance is therefore a critical factor related to rehabilitation addressing dexterity of persons with upper limb injuries.
Persons with unilateral dexterity loss of the dominant limb have two challenges
they are forced to complete two handed tasks with one hand.
the remaining limb, which primarily functioned as the supporting limb, must assume dexterity responsibilities of the dominant limb.
Hand dominance is therefore a critical factor related to rehabilitation addressing dexterity of persons with upper limb injuries.
Persons with unilateral dexterity loss of the dominant limb have two challenges
they are forced to complete two handed tasks with one hand.
the remaining limb, which primarily functioned as the supporting limb, must assume dexterity responsibilities of the dominant limb.
Hand dominance is therefore a critical factor related to rehabilitation addressing dexterity of persons with upper limb injuries.
Leading cause of upper limb amputations is trauma occurring in males ages 15-25 years,
Most of traumatic amputation happen on dominant limb
vascular complications of diseases.
No limb prefernces
cancer/tumors (common cause of more proximal amputations such as a shoulder disarticulation or forequarter amputation)
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Medica Stem Cells regenerative treatments are minimally invasive non-surgical procedures. Treatments provide long-lasting relief from symptoms with minimal downtime and enhance recovery within a short period using your own body's healing power to treat knee arthritis and knee-related injuries. Our patients benefit from reduced pain and enhanced functionality of the knee without undergoing surgery or knee replacement.
Get the best treatment for plantar fasciitis and enjoy a long walk as you do before. Active Family Chiropractic uses rage of therapies, including manipulation, stretching, ultrasound, and soft tissue work to treat plantar fasciitis. Our qualified staff will recommend orthotics and useful exercises you can do at home to gently stretch tight muscles and tendons. To hire the services of Plantar Fasciitis Treatment Chiropractic, visit us at https://swistakchiro.com/plantar-fasciitis/
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
3. What is Plantar Fasciitis?
• Plantar fasciitis is a painful and debilitating condition.
• It primarily affects athletes, people whose jobs require them to stand for long periods of time.
• And those who put heavy stress on their feet.
• It involves inflammation of the plantar fascia, the strands of connective tissue that run along the sole of the foot, linking
the heel of the foot to the ball and toes.
• The plantar fascia protects and relieves pressure from the bottom of your foot because it acts like a shock-absorbing
bowstring.
• However, it can tear due to repetitive tension and stress. When it is stretched and torn, it becomes inflamed, resulting in
plantar fasciitis.
4. The inflammation can be caused by
trauma from an injury, or from overuse of
the tissue.
It usually manifests as sharp pain in the
heel or sole of the foot and an inability to
point the toes upward.
If left untreated, it can lead to other and
more severe orthopaedic conditions in
the foot, shin, and knee.
5. How can Regenerative Therapy be used in Plantar fasciitis
treatment?
• Traditional treatment for plantar fasciitis often required a combination of orthopaedic foot supports, physical therapy, and
cortisone injections.
• Most people recover completely within a year. In extreme cases, surgery is used to release the tension on the plantar
fascia.
• However, the best way to actually heal the injury and provide long-lasting improvement is through orthobiologic
Regenerative treatments such as Prolotherapy and Platelet Rich Plasma (PRP).
• For actual tears in the plantar fascia, mesenchymal cell treatment may also be a viable option.
• These treatments aim to stimulate the connective tissue’s ability to heal and regenerate the torn plantar fascia.
6. How can Regenerative Therapy be used in Plantar fasciitis
treatment?
• This can permanently provide pain relief and prevent further damage as you continue to enjoy your daily physical
activities.
• These orthobiologic injections for plantar fasciitis often work better than the traditional cortisone shots, since they not
only soothe the pain but can also promote regeneration of damaged tissue.
• Repeated cortisone shots can actually lead to further damage to the affected tendons, but the same is not true of stem
cell-based therapy.
7. Prolotherapy
• Prolotherapy is a non-surgical treatment that involves targeted injections.
• The solution used in this treatment contains a local anaesthetic and concentrated dextrose
(steroids are not used).
• This procedure stimulates the tissues’ natural ability to repair.
• Afterwards, this may be followed by a stem cell treatment to aid in regeneration.
8. Platelet-Rich Plasma Therapy
• There is another non-surgical treatment for plantar fasciitis which involves platelet-rich plasma. This stimulates the tissue
to release growth factors and attract other cells.
• This is especially useful for helping stem cells concentrate on the damaged area of the connective tissue.
• It is an autologous procedure where the platelets are harvested from the patient’s own blood. After separating the
platelets in a centrifuge, it is injected into the source of pain or point of injury.
• The key is to provide the treatments to not only the Plantar Fasciitis, but also the ankle when necessary. If you had a
previous ankle injury, it is essential to heal both injuries to the point where the foot can return to normal, healthy
function. That is the path to returning to all of the activities you enjoy that depend on a strong, painless foot and ankle.
9. When do I See Results?
• Regenerative therapy for plantar fasciitis only takes a few hours to complete.
• It is performed in an outpatient setting, no general anaesthesia is required and most patients don’t need
post-operative pain medication.
• Patients will be able to go home almost immediately after the injection is done.
• Since this therapy is an orthobiological treatment that requires time for the cells to restore the damaged
areas in the foot, patients will not feel the effect of the injection immediately.
• On average, most patients will start to see signs of improvement in the form of reduced pain or increased
function within 30 days.
10. Is this Plantar Fasciitis Treatment Safe?
• Regenerative Therapy for plantar fasciitis is a safe alternative to surgery and other traditional
plantar fasciitis treatments.
• Since we only use Cells and PRP that were harvested from the same patient, the risk of infections
or rejection is virtually non-existent.
11. Am I a Candidate for Regenerative therapy?
• In general, Regenerative Therapy can be utilised by anyone, regardless of the age, race, or gender.
• However, in order to determine if you are a good candidate and will benefit the most from this treatment,
you will need to schedule an appointment with our Clinic to have assessment done by our Consultant, who
will review your medical records and determine if you are a qualified candidate for our therapy.
• The choice of treatment is then at the discretion of the Consultant and is based on your unique case.
• Regenerative Therapy is not suitable for all conditions and all patients.
• Only the doctor will be able to advise if you are a suitable candidate.
• The final outcome of the treatment and extent of improvement varies from one patient to another.
12. Contact us
• Website: https://medicastemcells.com/
• Contact us: https://medicastemcells.com/contact-us/