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In this presentation Daniel Faithful Miebaka provides detailed review of the condition that has fatal potential.
RESPIRATORY DISTRESS SYNDROME, PREVIOUSLY HYALINE MEMBRANE DISEASE IS A COMMON COMPLICATION OF PREMATURITY WITH MORTALITY ALMOST 100% IN THE ABSENCE OF PULMONARY SURFACTANT ADMINISTRATION, ESPECIALLY IN LOW RESOURCE SETTINGS LIKE OURS.
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RESPIRATORY DISTRESS SYNDROME, PREVIOUSLY HYALINE MEMBRANE DISEASE IS A COMMON COMPLICATION OF PREMATURITY WITH MORTALITY ALMOST 100% IN THE ABSENCE OF PULMONARY SURFACTANT ADMINISTRATION, ESPECIALLY IN LOW RESOURCE SETTINGS LIKE OURS.
Struggling with intense fears that disrupt your life? At Renew Life Hypnosis, we offer specialized hypnosis to overcome fear. Phobias are exaggerated fears, often stemming from past traumas or learned behaviors. Hypnotherapy addresses these deep-seated fears by accessing the subconscious mind, helping you change your reactions to phobic triggers. Our expert therapists guide you into a state of deep relaxation, allowing you to transform your responses and reduce anxiety. Experience increased confidence and freedom from phobias with our personalized approach. Ready to live a fear-free life? Visit us at Renew Life Hypnosis..
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India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
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Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
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2. OBJECTIVES
Introduction of RDS
Definition of RDS
Enlist the causes of RDS
To elaborate the pathophysiology
To enlist the sign & symptoms
To discuss the diagnostic evaluation
Describe the management of RDS
Health education
Conclusion
Bibliography
3. INTRODUCTION
Respiratory distress syndrome (RDS) occurs in babies born
early (premature) whose lungs are not fully developed.
Also known as neonatal respiratory distress syndrome.
The earlier the infant is born, the more likely it is for them to
have RDS and need extra oxygen and help breathing.
4. INCIDENCE
The incidence of RDS is inversely related to
gestational age.It occurs in 98% of preterm infants
betewee n 22 and 24 weeks gestation but only 25 %
of those with bright weight between 1.25 – 1.5 kg.
5. DEFINITION
Neonatal respiratory distress syndrome (NRDS) is more
common in premature babies born six weeks or more before
their due dates. It usually develops within the first 24 hours
after birth.
It is a syndrome of premature neonates that is characterized
by progressive and usually fetal respiratory failure resulting
from atelectasis and immature lungs.
11. SYMPTOMS
Fast breathing very soon after birth
Grunting “ugh” sound with each breath.
Widening (flaring) of the nostrils with each breath
Chest retractions – skin over the breastbone and ribs pulls in
during breathing
19. MANAGEMENT
Mediacal management:
1. Neonatal suspected to RDS need to be treated in NICU
2. Administer IV fluids & oxygen start oxygen therapy depends
on the condition.
3. Maintain oxygen saturation between 90-95%
4. Administration of exogenous surfectant through ET tube
directly into trachea.
20. CONT….
Medicine
1. Antibiotics, aminoglycosides, ampicillin,
Amoxicillin, Procaine penicillin usually given for
7-10 days.
2. Muscle relaxants : pancuronium
3. Antacids: sodium bicarbonate, sodium citrate
21. SURFACTANT THERAPY
Surfectant is isurfactant in all neonates with RDS.
Adequate oxygenation, ventilation and monitoring should be
started before administration surfectant.
Dose 100mg/kg body weight 2-4 divided doses as 6-12
hours apart.
Depending upon the baby’s condition repeated dose of
surfectant need to be administered.
22. NURSING MANAGEMENT
1. Maintain adequate hydration and electrolyte status.
2. Administer antibiotics to reduce the infections.
3. Maintain acid base balance.
4. Fluid and electrolyte management: Electrolyte balance,
fluids, calcium and glucose homeostasis are all equally
important
5. IV line for fluid/hydration, nutrition and medication.
6. Maintain saturation level.
23. HEALTH EDUCATION
To prevent premature birth can help prevent neonatal RDS.
Good prenatal care and regular checkups beginning as soon
as a woman discovers she is pregnant can help avoid
premature birth.
Maintain proper hygiene to prevent infections.
Provide iron rich diet to the pregnant mother
24. CONT….
Give your child over-the-counter and prescription medicines
only as told by your child’s health care provider.
26. CONCLUSION
RDS is the commonest cause of respiratory distress in the
newborn, particularly, in preterm infants. It carries a high
mortality rate and the incidence is more than that
documented in the Western world.
27. BIBLIOGRAPHY
Book reference:
1. Dutta Parul, textbook of pediatrics, 3rd edition, published by Jaypee Brothers, page no. 306-
309.
2. Sharma Rimple, textbook of pediatrics, 2nd edition, published by Jaypee Brothers, page no.
256-258.
Net reference:
1. www.slideshare .com
2. www.medlineplus.com
3. www.wikipedia.com