This document discusses the development of railroads in the United States from before the Civil War to 1898 and how railroads impacted industry. It describes how railroads transported natural resources like copper, lead, and coal from factories in the West to eastern cities for manufacturing. The document also outlines some major manufacturing centers that emerged in American cities and the industries they became known for, such as textiles in New England, automobiles in Detroit, steel in Pittsburgh, and meat packing in Chicago.