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Psoriatic arthritis
Psoriatic arthritis (PsA) is a type of joint pains, that affects people who have skin psoriasis — a
condition with red, raised skin, with white and silvery flakes. Around 30% of psoriasis patients
will develop Psoriatic Arthritis. Most people develop psoriasis first and later develop psoriatic
arthritis,butthejoint problemscansometimesbeginbeforetheskinpsoriasis.PsoriaticArthritis
canaffect anyage group(fromchildren tooldage group).
Symptoms-
Jointpain,stiffnessandswellingare the main symptoms. Itcanaffect anyjointofbody. Other
commonsymptomsincludepainful, sausage-likeswellingofyourfingersandtoes(Dactylitis),
heelpain (Enthesitis).Spineinvolvement causesneckandbackpain withearlymorningstiffness
similartospondyloarthritis(Ankylosingspondylitis).Somepatientswilldeveloprecurrent
painfulRedeyeswithblurredvision (uveitis/iritis)andBowelinflammation withrepeated
episodesofloose stool(IBD-InflammatoryBoweldisease). Theyarealsoat higherriskof
cardiovasculardiseaseandNon-AlcoholicFattyliverdisease. Arthritismutilansacomplication
ofPsAleadstodestructionofsmallbonesoffingersleadingtosevere,painful deformitiesof
handjoints.Symptomscanrange frommildtosevere.In bothpsoriasisandpsoriaticarthritis,
diseaseflaresmayalternatewithperiodsofremission.
Causes
JPsoriaticarthritisoccurswhenyourbody'simmunesystemmistakenlyattacksthejointandskin.
Genetic and environmental factors play a role. Many people with psoriatic arthritis have a family
history of psoriasis or psoriatic arthritis. Physical trauma, viral or bacterial infection — may
trigger psoriatic arthritis in people with an inherited tendency.
Riskfactors forPsoriatic arthritisinclude-People who have pitted, deformed psoriatic nails and
familyhistoryofpsoriasis.
Diagnosis
Clinical examination of joints, skin and nails helps in diagnosis. No single test can confirm a
diagnosis of psoriatic arthritis. But some tests can rule out other causes of joint pain, such as
rheumatoidarthritisorgout.Imaging-x-raysofhandsandfeet,Ultrasoundofjoints,MRIofjoints
or spine Lab test- ESR, CRP, HLA B27, RA factor (to rule out rheumatoid arthritis), joint fluid
analysisifneededtorule out othercauses.
Treatment
Nocure existsforpsoriaticarthritis,sotreatment mainlyfocuseson controllinginflammationin
youraffectedjointstopreventjoint painanddeformities.
Medications
Drugsusedtotreatpsoriaticarthritisinclude:
• NSAIDs.Nonsteroidal anti-inflammatory drugs (NSAIDs) relieves pain and
reduces inflammation. These may be prescribed for short period. Long-term
usageleads to sideeffects likegastritis,liver and kidney damage.
• Disease-modifying anti-rheumatic drugs (DMARDs). These drugs slows the
progression of psoriatic arthritis and save the joints from permanent damage.
Common DMARDs include Methotrexate, Leflunomide, Sulfasalazine and
Apremilast.SometimesAzathioprineandCyclosporinearealsoused.Sideeffects
vary butmay includeliver damage,bonemarrow suppressionand infections.
• Biologic agents. These medications target specific parts of the immune system
that trigger inflammation. This newer class of DMARDs includes Adalimumab,
Etanercept, Golimumab, Infliximab, Ixekizumab, Secukinumab, Tofacitinib and
Ustekinumab.Thesedrugsmayincreasetheriskofinfections.Biologicagentscan
beused aloneor combined withDMARDs suchas methotrexate.
Surgicalandotherprocedures
• Steroid injections - injected into anaffected joint,reduces theinflammation
quickly.
• Jointreplacementsurgery- for severely damaged joints.
Lifestyleandhomeremedies
• Protectyour joints- Avoid straining your joints or lifting weights .
• Maintain ahealthy weight,avoid stress,adequatesleep.
• Thebestway to increasenutrients whilelimiting calories is to eatmoreplant-
based foods — fruits,vegetables and wholegrains.
• Exerciseregularly- Tokeep your joints flexible.Types ofexercises thatareless
stressful on joints includebiking,swimming and walking.
• Stop smoking.Smoking is associated withahigher riskofdeveloping severe
psoriasis and arthritis.
• Limitalcohol use. Alcohol canincreaseyour riskofpsoriasis,decreasethe
effectiveness ofyour treatmentand increasesideeffects frommedications.
Copingandsupport
Psoriaticarthritiscanbe particularlydiscouragingbecause oftheemotionalpaindueto
psoriasisandjoint pains. Thesupportoffriendsandfamilymakeatremendousdifference to
overcomethephysicalandpsychologicalchallenges.Forsome people,support groupscan offer
thesamebenefits.

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Psoriatic arthritis

  • 1. Psoriatic arthritis Psoriatic arthritis (PsA) is a type of joint pains, that affects people who have skin psoriasis — a condition with red, raised skin, with white and silvery flakes. Around 30% of psoriasis patients will develop Psoriatic Arthritis. Most people develop psoriasis first and later develop psoriatic arthritis,butthejoint problemscansometimesbeginbeforetheskinpsoriasis.PsoriaticArthritis canaffect anyage group(fromchildren tooldage group). Symptoms- Jointpain,stiffnessandswellingare the main symptoms. Itcanaffect anyjointofbody. Other commonsymptomsincludepainful, sausage-likeswellingofyourfingersandtoes(Dactylitis), heelpain (Enthesitis).Spineinvolvement causesneckandbackpain withearlymorningstiffness similartospondyloarthritis(Ankylosingspondylitis).Somepatientswilldeveloprecurrent painfulRedeyeswithblurredvision (uveitis/iritis)andBowelinflammation withrepeated episodesofloose stool(IBD-InflammatoryBoweldisease). Theyarealsoat higherriskof cardiovasculardiseaseandNon-AlcoholicFattyliverdisease. Arthritismutilansacomplication ofPsAleadstodestructionofsmallbonesoffingersleadingtosevere,painful deformitiesof handjoints.Symptomscanrange frommildtosevere.In bothpsoriasisandpsoriaticarthritis, diseaseflaresmayalternatewithperiodsofremission. Causes JPsoriaticarthritisoccurswhenyourbody'simmunesystemmistakenlyattacksthejointandskin. Genetic and environmental factors play a role. Many people with psoriatic arthritis have a family history of psoriasis or psoriatic arthritis. Physical trauma, viral or bacterial infection — may trigger psoriatic arthritis in people with an inherited tendency. Riskfactors forPsoriatic arthritisinclude-People who have pitted, deformed psoriatic nails and familyhistoryofpsoriasis. Diagnosis Clinical examination of joints, skin and nails helps in diagnosis. No single test can confirm a diagnosis of psoriatic arthritis. But some tests can rule out other causes of joint pain, such as rheumatoidarthritisorgout.Imaging-x-raysofhandsandfeet,Ultrasoundofjoints,MRIofjoints or spine Lab test- ESR, CRP, HLA B27, RA factor (to rule out rheumatoid arthritis), joint fluid analysisifneededtorule out othercauses. Treatment
  • 2. Nocure existsforpsoriaticarthritis,sotreatment mainlyfocuseson controllinginflammationin youraffectedjointstopreventjoint painanddeformities. Medications Drugsusedtotreatpsoriaticarthritisinclude: • NSAIDs.Nonsteroidal anti-inflammatory drugs (NSAIDs) relieves pain and reduces inflammation. These may be prescribed for short period. Long-term usageleads to sideeffects likegastritis,liver and kidney damage. • Disease-modifying anti-rheumatic drugs (DMARDs). These drugs slows the progression of psoriatic arthritis and save the joints from permanent damage. Common DMARDs include Methotrexate, Leflunomide, Sulfasalazine and Apremilast.SometimesAzathioprineandCyclosporinearealsoused.Sideeffects vary butmay includeliver damage,bonemarrow suppressionand infections. • Biologic agents. These medications target specific parts of the immune system that trigger inflammation. This newer class of DMARDs includes Adalimumab, Etanercept, Golimumab, Infliximab, Ixekizumab, Secukinumab, Tofacitinib and Ustekinumab.Thesedrugsmayincreasetheriskofinfections.Biologicagentscan beused aloneor combined withDMARDs suchas methotrexate. Surgicalandotherprocedures • Steroid injections - injected into anaffected joint,reduces theinflammation quickly. • Jointreplacementsurgery- for severely damaged joints. Lifestyleandhomeremedies • Protectyour joints- Avoid straining your joints or lifting weights . • Maintain ahealthy weight,avoid stress,adequatesleep. • Thebestway to increasenutrients whilelimiting calories is to eatmoreplant- based foods — fruits,vegetables and wholegrains.
  • 3. • Exerciseregularly- Tokeep your joints flexible.Types ofexercises thatareless stressful on joints includebiking,swimming and walking. • Stop smoking.Smoking is associated withahigher riskofdeveloping severe psoriasis and arthritis. • Limitalcohol use. Alcohol canincreaseyour riskofpsoriasis,decreasethe effectiveness ofyour treatmentand increasesideeffects frommedications. Copingandsupport Psoriaticarthritiscanbe particularlydiscouragingbecause oftheemotionalpaindueto psoriasisandjoint pains. Thesupportoffriendsandfamilymakeatremendousdifference to overcomethephysicalandpsychologicalchallenges.Forsome people,support groupscan offer thesamebenefits.