Inflammation is the body's response to infection or injury and is characterized by redness, swelling, heat, and pain. It is caused by the release of chemicals from white blood cells that increase blood flow and cause fluid leakage into tissues. Inflammatory diseases like arthritis occur when the immune system mistakenly attacks the body's own tissues. Symptoms of inflammation can affect joints as well as internal organs. Treatment focuses on controlling the disease process, relieving pain, and maintaining joint function through medications, exercise, and surgery.
The uploaded content is related to Arthritis.In this, more emphasized topics are Rehabilitation and Nursing care of patients who are suffering from disabilities and developed deformities due to arthritis.This content have many related images , videos etc so that learners will get a better idea of the disease condition, also it will be helpful to all nursing students to serve the patients with comprehensive care.
The uploaded content is related to Arthritis.In this, more emphasized topics are Rehabilitation and Nursing care of patients who are suffering from disabilities and developed deformities due to arthritis.This content have many related images , videos etc so that learners will get a better idea of the disease condition, also it will be helpful to all nursing students to serve the patients with comprehensive care.
Salas, V. (2024) "John of St. Thomas (Poinsot) on the Science of Sacred Theol...Studia Poinsotiana
I Introduction
II Subalternation and Theology
III Theology and Dogmatic Declarations
IV The Mixed Principles of Theology
V Virtual Revelation: The Unity of Theology
VI Theology as a Natural Science
VII Theology’s Certitude
VIII Conclusion
Notes
Bibliography
All the contents are fully attributable to the author, Doctor Victor Salas. Should you wish to get this text republished, get in touch with the author or the editorial committee of the Studia Poinsotiana. Insofar as possible, we will be happy to broker your contact.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
2. ا
ﻟ
ﺼ
ﻔ
ﺤ
ﺔ
1
What Is Inflammation?
Inflammation is a process by which the body's white blood cells and
substances they produce protect us from infection with foreign organisms,
such as bacteria and viruses.
However, in some diseases, like arthritis, the body's defense system -- the
immune system -- triggers an inflammatory response when there are no
foreign invaders to fight off. In these diseases, called autoimmune diseases,
the body's normally protective immune system causes damage to its own
tissues. The body responds as if normal tissues are infected or somehow
abnormal.
What Diseases Are Associated with Inflammation?
Some, but not all, types of arthritis are the result of misdirected inflammation.
Arthritis is a general term that describes inflammation in the joints. Some types of
arthritis associated with inflammation include the following:
§ Rheumatoid arthritis
§ Psoriatic arthritis
§ Gouty arthritis
Other painful conditions of the joints and musculoskeletal system that may not be
associated with inflammation include osteoarthritis, fibromyalgia, muscular low
back pain, and muscular neck pain.
What Are the Symptoms of Inflammation?
Symptoms of inflammation include:
§ Redness
§ Swollen joint that's sometimes warm to the touch
§ Joint pain
§ Joint stiffness
§ Loss of joint function
Often, only a few of these symptoms are present.
Inflammation may also be associated with general flu-like
symptoms including:
3. ا
ﻟ
ﺼ
ﻔ
ﺤ
ﺔ
2
§ Fever
§ Chills
§ Fatigue/loss of energy
§ Headaches
§ Loss of appetite
§ Muscle stiffness
What Causes Inflammation and What Are Its Effects?
When inflammation occurs, chemicals from the body's white blood cells are
released into the blood or affected tissues to protect your body from foreign
substances. This release of chemicals increases the blood flow to the area of
injury or infection, and may result in redness and warmth. Some of the
chemicals cause a leak of fluid into the tissues, resulting in swelling. This
protective process may stimulate nerves and cause pain.
The increased number of cells and inflammatory substances within the joint
cause irritation, swelling of the joint lining and, eventually, wearing down of
cartilage (cushions at the end of bones).
How Are Inflammatory Diseases Diagnosed?
Inflammatory diseases are diagnosed after careful evaluation of the following:
• Complete medical history and physical exam with attention to:
o The pattern of painful joints and whether there is evidence of inflammation
o Presence of joint stiffness in the morning
o Evaluation of other symptoms
• Results of X-rays and blood tests
Can Inflammation Affect Internal Organs?
Yes. Inflammation can affect organs as part of an autoimmune disorder. The
type of symptoms depend on which organs are affected. For example:
§ Inflammation of the heart (myocarditis) may cause shortness of breath or
fluid retention.
§ Inflammation of the small tubes that transport air to the lungs may cause
shortness of breath.
§ Inflammation of the kidneys (nephritis) may cause high blood pressure or
kidney failure.
4. ا
ﻟ
ﺼ
ﻔ
ﺤ
ﺔ
3
Pain may not be a primary symptom of an inflammatory disease, since many
organs do not have many pain-sensitive nerves. Treatment of organ
inflammation is directed at the cause of inflammation whenever possible.
How Are Inflammatory Joint Diseases Treated?
There are a number of treatment options for inflammatory diseases, like arthritis,
including medications, rest, exercise, and surgery to correct joint damage. The
type of treatment prescribed will depend on several factors, including the type of
disease, the person's age, type of medications he or she is taking, overall health,
medical history, and severity of symptoms.
The goals of treatment are the following:
§ Correct, control, or slow down the underlying disease process
§ Avoid or modify activities that aggravate pain
§ Relieve pain through pain medications and anti-inflammatory drugs
§ Maintain joint movement and muscle strength through physical therapy
§ Decrease stress on the joints by using braces, splints, or canes as needed
What Drugs Are Used to Treat Inflammatory Diseases?
There are many drugs available to decrease joint pain, swelling and
inflammation, and possibly prevent or minimize the progression of the
inflammatory disease. They are often used in combination due to their
differing effects. The medications include:
§ Nonsteroidal anti-inflammatory drugs (NSAIDs such as aspirin,
ibuprofen, or naproxen)
§ Corticosteroids (such as prednisone)
§ Antimalarial medications (such as hydroxychloroquine)
§ Other oral drugs known as DMARDs (disease-modifying
antirheumatic drugs), including methotrexate, sulfasalazine,
leflunomide, azathioprine, and cyclophosphamide
§ Biologic drugs such as infliximab, etanercept, adalimumab,
certolizumab, golimumab, abatacept, tocilizumab, and rituximab
Some of these medications are also used to treat other conditions such as
cancer or inflammatory bowel disease, or to reduce the risk of rejection of
a transplanted organ. However, when "chemotherapy" types of
medications (such as methotrexate or cyclophosphamide) are used to treat
5. ا
ﻟ
ﺼ
ﻔ
ﺤ
ﺔ
4
inflammatory diseases, the doses are sometimes significantly lower and
the risks of side effects tend to be less than when prescribed in higher
doses for cancer treatment.
When you are prescribed any medication, it is important to meet with your
doctor regularly so he or she can detect the development of any side
effects.