Photo system II is a large pigment-protein complex found in the thylakoid membrane of photosynthetic organisms that converts sunlight into chemical energy. It catalyzes the splitting of water molecules into protons, electrons, and oxygen to produce ATP and NADPH. Photo system II contains at least 99 cofactors including 35 chlorophyll a molecules, 12 beta-carotene molecules, and a manganese calcium oxide cluster that catalyzes the water-splitting reaction.