Protease Enzyme and their functions, sources, classification and applications.

1. “PROTEASE ENZYME”
By
SyedaSadafWajahat

2. What are Proteases?
▪ Proteases are the enzymes which breakdown
the proteins into smaller polypeptides or amino
acids (proteolysis).
▪ Proteases, as also known as as peptidases or
proteinases.

3. Functions of
Proteases
• Digestion and catabolism of proteins.
• Blood coagulation.
• Cell division, growth, apoptosis and migration.
• Protein recycling and transport across membranes.
• Mediate immune response.
• Wound healing and muscle soreness.
• Video:
https://www.youtube.com/watch?v=DvqZea4dq5E

4. Sources of Proteases
Sources
Plants
(e.g. Papain,
Bromelain)
Microorganisms
(e.g. Subtilisin,
Thermolysin)
Animals
(e.g. Trypsin,
Pepsin)

5. Classification of Proteases

6. On the basis of
reaction they catalyze

8. On the basis of site of enzyme
action

10. On the basis of pH

11. pH
Acidic
Alkaline
Neutral

12. On the basis of mechanism of
catalysis

13. Threonine
peptidase
Asparagine
peptidase
Aspartic
peptidase
Cysteine
peptidase
Glutamic
peptidase
Metallo-
peptidase
Serine
peptidase

14. Applications of Proteases