The application of post-light semiconductor-based
next-generation sequencing in clinical cases of preimplantation
aneuploidy screening (PGS) with fresh embryo transfer.
The application of post-light semiconductor-based
next-generation sequencing in clinical cases of preimplantation
aneuploidy screening (PGS) with fresh embryo transfer.
Synthetic biology with Three parent Baby presentation and legal issues relate...Vikram Jeet Singh
This presentation deals with the use of synthetic biology in current world to produce synthetic microorganisms and issues related to that. Three parent baby is also a part of synthetic biology where faulty mitochondria of one mother are replaced by healthy mitochondria of other women. It is a revolution towards the production of the designer baby. This designer baby will be a concern shortly as human are acting like God and may be started to produce the baby with other unknown defects or diseases which might be uncurable in the near future.
The procedure is called as "three-parent" in vitro fertilization because the babies, born from genetically modified embryos, would have DNA from a mother, a father and from a healthier female donor to prevent some serious incurable diseases passing on.
About us: FertilityConsultants.ca is people choice of consulting firm International Surrogacy in Canada which is fully devoted in helping couples who are having difficulty in trying to conceive.
Эко корпоратив. Корпоративное мероприятие с выгодой для своего бизнеса. Fedor Tarabukin
Из этой презентации Вы узнаете как провести корпоративное
мероприятие с выгодой для
своего бизнеса.
Вы хотите повысить имидж Вашей компании?
Вам интересно узнать, как окупить средства,
вложенные в корпоративное мероприятие?
Вы хотите создать вдохновение в коллективе?
Вам важно, чтобы сотрудники гордились тем,
что работают в Вашей компании?
Synthetic biology with Three parent Baby presentation and legal issues relate...Vikram Jeet Singh
This presentation deals with the use of synthetic biology in current world to produce synthetic microorganisms and issues related to that. Three parent baby is also a part of synthetic biology where faulty mitochondria of one mother are replaced by healthy mitochondria of other women. It is a revolution towards the production of the designer baby. This designer baby will be a concern shortly as human are acting like God and may be started to produce the baby with other unknown defects or diseases which might be uncurable in the near future.
The procedure is called as "three-parent" in vitro fertilization because the babies, born from genetically modified embryos, would have DNA from a mother, a father and from a healthier female donor to prevent some serious incurable diseases passing on.
About us: FertilityConsultants.ca is people choice of consulting firm International Surrogacy in Canada which is fully devoted in helping couples who are having difficulty in trying to conceive.
Эко корпоратив. Корпоративное мероприятие с выгодой для своего бизнеса. Fedor Tarabukin
Из этой презентации Вы узнаете как провести корпоративное
мероприятие с выгодой для
своего бизнеса.
Вы хотите повысить имидж Вашей компании?
Вам интересно узнать, как окупить средства,
вложенные в корпоративное мероприятие?
Вы хотите создать вдохновение в коллективе?
Вам важно, чтобы сотрудники гордились тем,
что работают в Вашей компании?
Lecture on prenatal genetic diagnostic techniques and their value in detection of prenatal genetic anomalies. This lecture details techniques employed in the common diagnostic interventions used in prenatal period and their usefulness.
Thsi presentation is a sincere attempt to demonstrate the aseptic techniques needed to collect blood culture, urine culture, diagnostic lumbar puncture. Disscussion about the use of there modalities in neonatology practice and the ways to increase their sensitivity and specificity is done.
this presentation is also available in a video lecture format at my Youtube channel - "NeonatoHub". Hope you enjoy it more in that format.
https://www.youtube.com/watch?v=vZ71vymGVC8
widespread epidemic of Zika virus (ZIKV) infection was reported in 2015 in South and Central America and the Caribbean. A major concern associated with this infection is the apparent increased incidence of microcephaly in fetuses born to mothers infected with ZIKV. In this report, we describe the case of an expectant mother who had a febrile illness with rash at the end of the first trimester of pregnancy while she was living in Brazil. Ultrasonography performed at 29 weeks of gestation revealed microcephaly with calcifications in the fetal brain and pla-centa. After the mother requested termination of the pregnancy, a fetal autopsy was performed. Micrencephaly (an abnormally small brain) was observed, with almost complete agyria, hydrocephalus, and multifocal dystrophic calcifications in the cortex and subcortical white matter, with associated cortical displacement and mild focal inf lammation. ZIKV was found in the fetal brain tissue on reverse-transcriptase–polymerase-chain-reaction (RT-PCR) assay, with consistent findings on electron microscopy. The complete genome of ZIKV was recovered from the fetal brain
Cytomegalovirus infection in kidny transplantationhadi lashini
HCMV infection is a frequent complication of kidney transplantation, especially in the period 1 to 4 months after transplantation. Overall incidences of HCMV infection and disease during the first 100 days post-transplantation, 60% and 25% respectively, when no HCMV prophylaxis or pre-emptive therapy is given. HCMV infection is an independent risk-factor for kidney graft rejection and associated with high morbidity and mortality rates .
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024Tobias Schneck
As AI technology is pushing into IT I was wondering myself, as an “infrastructure container kubernetes guy”, how get this fancy AI technology get managed from an infrastructure operational view? Is it possible to apply our lovely cloud native principals as well? What benefit’s both technologies could bring to each other?
Let me take this questions and provide you a short journey through existing deployment models and use cases for AI software. On practical examples, we discuss what cloud/on-premise strategy we may need for applying it to our own infrastructure to get it to work from an enterprise perspective. I want to give an overview about infrastructure requirements and technologies, what could be beneficial or limiting your AI use cases in an enterprise environment. An interactive Demo will give you some insides, what approaches I got already working for real.
Software Delivery At the Speed of AI: Inflectra Invests In AI-Powered QualityInflectra
In this insightful webinar, Inflectra explores how artificial intelligence (AI) is transforming software development and testing. Discover how AI-powered tools are revolutionizing every stage of the software development lifecycle (SDLC), from design and prototyping to testing, deployment, and monitoring.
Learn about:
• The Future of Testing: How AI is shifting testing towards verification, analysis, and higher-level skills, while reducing repetitive tasks.
• Test Automation: How AI-powered test case generation, optimization, and self-healing tests are making testing more efficient and effective.
• Visual Testing: Explore the emerging capabilities of AI in visual testing and how it's set to revolutionize UI verification.
• Inflectra's AI Solutions: See demonstrations of Inflectra's cutting-edge AI tools like the ChatGPT plugin and Azure Open AI platform, designed to streamline your testing process.
Whether you're a developer, tester, or QA professional, this webinar will give you valuable insights into how AI is shaping the future of software delivery.
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
PHP Frameworks: I want to break free (IPC Berlin 2024)Ralf Eggert
In this presentation, we examine the challenges and limitations of relying too heavily on PHP frameworks in web development. We discuss the history of PHP and its frameworks to understand how this dependence has evolved. The focus will be on providing concrete tips and strategies to reduce reliance on these frameworks, based on real-world examples and practical considerations. The goal is to equip developers with the skills and knowledge to create more flexible and future-proof web applications. We'll explore the importance of maintaining autonomy in a rapidly changing tech landscape and how to make informed decisions in PHP development.
This talk is aimed at encouraging a more independent approach to using PHP frameworks, moving towards a more flexible and future-proof approach to PHP development.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
JMeter webinar - integration with InfluxDB and GrafanaRTTS
Watch this recorded webinar about real-time monitoring of application performance. See how to integrate Apache JMeter, the open-source leader in performance testing, with InfluxDB, the open-source time-series database, and Grafana, the open-source analytics and visualization application.
In this webinar, we will review the benefits of leveraging InfluxDB and Grafana when executing load tests and demonstrate how these tools are used to visualize performance metrics.
Length: 30 minutes
Session Overview
-------------------------------------------
During this webinar, we will cover the following topics while demonstrating the integrations of JMeter, InfluxDB and Grafana:
- What out-of-the-box solutions are available for real-time monitoring JMeter tests?
- What are the benefits of integrating InfluxDB and Grafana into the load testing stack?
- Which features are provided by Grafana?
- Demonstration of InfluxDB and Grafana using a practice web application
To view the webinar recording, go to:
https://www.rttsweb.com/jmeter-integration-webinar
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
4. Researches Malformations of cortical development in children with congenital cytomegalovirus infection - A study of nine children with proven congenital cytomegalovirus infection Development of Lissencephaly in the fetus as direct consequence of early infection. Most common vertically transmitted disease rate of the infection ranging: 0.2 to 2.4% in newborn infants 40.000 infants per year
5. Chemical remedy Oral Hexadecyloxypropyl-Cidofovir Therapy in Pregnant Guinea Pigs Improves Outcome in the Congenital Model of Cytomegalovirus Infection Alternative orally supply analog of the existing drug, Cidofovir Only proved effiency of Guinea Pigs
7. Hypothesis The augment of antibodies IgG and IgM may reduce the presence of CVM, representing a minor risk to the fetus in developing Lissencephaly.
15. Prepare research models Mice from 12-13 days Anesthiaze mice Inject with CMV vector solution with a glass micropipette Place pipette for an 30 s and then slowly withdrawn.
16. Research model’s distribution Groups: IL 6 IL 28 IgG IgM Sub-groups: A= every week B= every 48 hrs C= every three days
18. Extract serology: CVS Placenta is the common path Chronic Villous Sampling Suction of a tissue from placenta
19. Step: ELISPOT Quantify presence of IgG and IgM in all experimental groups Procedure according to: “General ELISPOT procedure” by abcam.com
20. Step: Direct immunofluorescence Cualitative presence of IgG and IgM in all experimental groups Process according to: “Immunostaining of cells in tissue culture” by ENCORE biotechnology INC.
21. Spected results ELISPOT will indicate: augment in antibodies in experimental groups will mean lower presence of CMV Direct immunofluorescence: Control group will be brighter than experimental groups will mean high presence of CMV
22. Bibliography Bosnjak VM, Daković I, et al. Malformations of cortical development in children with congenital cytomegalovirus infection - A study of nine children with proven congenital cytomegalovirus infection. January, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21648339 Ravo FJ, Bernstein DI, et al. Oral Hexadecyloxypropyl-Cidofovir Therapy in Pregnant Guinea Pigs Improves Outcome in the Congenital Model of Cytomegalovirus Infection. November 15, 2011. http://www.ncbi.nlm.nih.gov/pubmed?term=Oral%20Hexadecyloxypropyl-Cidofovir%20Therapy%20in%20Pregnant%20Guinea%20Pigs%20Improves%20Outcome%20in%20the%20Congenital%20Model%20of%20Cytomegalovirus%20Infection%20
23. Araswathy TS, Az-Ulhusna A, et al. Seroprevalence of cytomegalovirus infection in pregnant women and associated role in obstetric complications: a preliminary study. March, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21710852 Kaneda K, Kasahara H, et al.Selective Optical Control of Synaptic Transmission in the Subcortical Visual Pathway by Activation of Viral Vector-Expressed Halorhodopsin. April 5, 2011. http://www.ncbi.nlm.nih.gov/pubmed?term=Selective%20Optical%20Control%20of%20Synaptic%20Transmission%20in%20the%20Subcortical%20Visual%20Pathway%20by%20Activation%20of%20Viral%20Vector-Expressed%20Halorhodopsin Boeckh, M. and Boivin, G. Quantitation of Cytomegalovirus: Methodologic Aspects and Clinical Applications. Clinical Microbiology Reviews, July 1998, p. 533-554, Vol. 11, No. 3. http://cmr.asm.org/cgi/content/full/11/3/533
Editor's Notes
Researches as Malformations of cortical development in children with congenital cytomegalovirus infection - A study of nine children with proven congenital cytomegalovirus infection affirm that... “Congenital cytomegalovirus (CMV) infection is the most common vertically transmitted disease with the rate of the infection ranging from 0.2 to 2.4% in newborn infants”.
A chemical remedy had already been experimented inOral Hexadecyloxypropyl-Cidofovir Therapy in Pregnant Guinea Pigs Improves Outcome in the Congenital Model of Cytomegalovirus Infectionas an alternative orally supply analog of the existing drug, Cidofovir, against CMV
125 pregnant women tested, IgG antibody was found 84% (105 women) of the times, but IgM only on 7.2% (9 women)It means that they weren’t always present, signifying lack of antibody levels. Therefore, that can be reasoned that... (hypothesis)
Musmusculus, because:resemblance to human, able to be infected with CMV, more ethical to work with than humans, small sized, highly fertile, principally because isgraded as ideal for ‘in vivo’ hybridomasto produce continuous supply of antibody. Division:9 for each experimental group + 3 for the control group.Image Citometri = stores image data and the microscopic parameters describing the optics during the acquisition.
Dextran Leukocyte Separation Kit = isolation of the PMN by dextran separation PMN Polymorphonuclear leukocytes:CMV DNA can be detected in different fractions of leukocytes like this one during active infectionFormaldehyde-Noidet P-40=solution made of a simple Aldehyde and a detergent.MRI= Magnetic Resonance Image
Selective Optical Control of Synaptic Transmission in the Subcortical Visual Pathway by Activation of Viral Vector-Expressed Halorhodopsin.Anestethiaze with ketamineand xylazineInject mice with unilateral pressure injections of 1.0–1.5 µl of CMV vector solution (Recombinant CMV) into the body using a glass micropipette with a tip diameter of 20–30 µm.Place pipette for an 30 s and then slowly withdrawn.
IL 6 =B-cell stimulatory factorIL 28=inmune defense against virusIgG= battle bacterial and viral infectionsIgM= first reponse against antigen presenceEach will be for a complete of period fifteen days, because the sampling can be made days before the offspring born.
After fifteen days of gestation, the CVS (Chronic Villous Sampling) in order to analyze the placenta tissue. Placenta is the organ where the mother supplies the fetus important needs for the development as nutritional and respiratory.
