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Principles of Cancer Treatment
Principles of Cancer Treatment
Always use Multimodal Therapy ie.
Combination of two or more approaches
from Surgery, Chemo, Radio and
Targeted therapy
Principles of Cancer Treatment
Stages of Cancer
• I Small tumor
• II I+ Regional mobile L.Ns.
• III Locally advanced
• IV Mets +nt
Principles of Cancer Treatment
• Local Tt
• Systemic Tt
• Surgery
• Radiotherapy
• Chemotherapy
• Hormonal therapy
• Targeted Therapy
Treatment modalities
Principles of Cancer Treatment
• Early disease
(Stage I&II)
• Advanced Disease
(Stage III&IV)
• CurativeTt
– Local Tt followed by
Systemic Tt
• Palliative Tt
– Systemic followed by
Local Tt
Principles of Cancer Surgery
Principles of Cancer Surgery
• Curative
– Removal of diseased organ with regional LNs
enblock.
– Achieve tumor free margins.
• Palliative –Surgery is the best palliation
• Reconstruction is required.
• Recent trend is to limit surgery –
Lumpectomy followed by RT.
Principles of Radiotherapy
Principles of Radiotherapy
• Alternative to surgery
• Tt of residual disease
• Repeat RT is ineffective.
Advantages of radiotherapy
Disadvantages of RT
• adverse effects are common;
• cure is uncommon, especially for large
tumors; and
• subsequent surgery is more difficult and
hazardous and survival is reduced further.
Disadvantages of RT
• adverse effects are common;
• cure is uncommon, especially for large
tumors; and
• subsequent surgery is more difficult and
hazardous and survival is reduced further.
Adverse effects of RT
Adverse effects of RT
• Oral mucositis
• Xerostomia
• loss of taste
• osteoradionecrosis
Principles of Chemotherapy
Principles of Chemotherapy
• Adjuvant CT –following curative surgery
• Palliative CT in inoperable disease- lower
dose.
• Neo-adjuvant CT- Before curative surgery
Recent Trend
• To Use Chemoradiotherapy as neo adjuvant
therapy
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Principles of cancer therapy.pptx

  • 1. Tips on using my ppt. 1. You can freely download, edit, modify and put your name etc. 2. Don’t be concerned about number of slides. Half the slides are blanks except for the title. 3. First show the blank slides (eg. Aetiology ) > Ask students what they already know about ethology of today's topic. > Then show next slide which enumerates aetiologies. 4. At the end rerun the show – show blank> ask questions > show next slide. 5. This will be an ACTIVE LEARNING SESSION x three revisions. 6. Good for self study also. 7. See notes for bibliography.
  • 3. Principles of Cancer Treatment Always use Multimodal Therapy ie. Combination of two or more approaches from Surgery, Chemo, Radio and Targeted therapy
  • 4. Principles of Cancer Treatment Stages of Cancer • I Small tumor • II I+ Regional mobile L.Ns. • III Locally advanced • IV Mets +nt
  • 5. Principles of Cancer Treatment • Local Tt • Systemic Tt • Surgery • Radiotherapy • Chemotherapy • Hormonal therapy • Targeted Therapy Treatment modalities
  • 6. Principles of Cancer Treatment • Early disease (Stage I&II) • Advanced Disease (Stage III&IV) • CurativeTt – Local Tt followed by Systemic Tt • Palliative Tt – Systemic followed by Local Tt
  • 8. Principles of Cancer Surgery • Curative – Removal of diseased organ with regional LNs enblock. – Achieve tumor free margins. • Palliative –Surgery is the best palliation • Reconstruction is required. • Recent trend is to limit surgery – Lumpectomy followed by RT.
  • 10. Principles of Radiotherapy • Alternative to surgery • Tt of residual disease • Repeat RT is ineffective.
  • 12. Disadvantages of RT • adverse effects are common; • cure is uncommon, especially for large tumors; and • subsequent surgery is more difficult and hazardous and survival is reduced further.
  • 13. Disadvantages of RT • adverse effects are common; • cure is uncommon, especially for large tumors; and • subsequent surgery is more difficult and hazardous and survival is reduced further.
  • 15. Adverse effects of RT • Oral mucositis • Xerostomia • loss of taste • osteoradionecrosis
  • 17. Principles of Chemotherapy • Adjuvant CT –following curative surgery • Palliative CT in inoperable disease- lower dose. • Neo-adjuvant CT- Before curative surgery
  • 18. Recent Trend • To Use Chemoradiotherapy as neo adjuvant therapy
  • 19. Get this ppt in mobile 1. Download Microsoft PowerPoint from play store. 2. Open Google assistant 3. Open Google lens. 4. Scan qr code from next slide.
  • 20. Get this ppt in mobile
  • 21. Get my ppt collection • https://www.slideshare.net/drpradeeppande/ edit_my_uploads • https://www.dropbox.com/sh/x600md3cvj8 5woy/AACVMHuQtvHvl_K8ehc3ltkEa?dl =0 • https://www.facebook.com/doctorpradeeppa nde/?ref=pages_you_manage

Editor's Notes

  1. drpradeeppande@gmail.com 7697305442