The document summarizes the key differences between fish, reptile, and human hearts. It notes that fish hearts are two-chambered with one atrium and ventricle and no separation between chambers. Reptile hearts vary, with some like lizards having a three-chambered heart with mixing of oxygenated and deoxygenated blood, while crocodiles and turtles have a four-chambered heart like birds and mammals. Human hearts are four-chambered with complete separation of oxygenated and deoxygenated blood into two pressure systems.