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Precellys homogenizers
The Precellys 24, a high-throughput tissue homogenizer, can handle up to 24 samples simultaneously with speeds ranging from 4000 to 6800 rpm, supporting a diverse range of biological materials. It features powerful 3D bead-beating technology, ensuring molecular integrity while allowing for reproducible results through over 1000 validated protocols. Complementary products include the Precellys 24-dual for medium throughput and the Minilys for personal use, alongside the Cryolys cooling system for safeguarding sensitive samples.
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Precellys homogenizers
- 1. Precellys 24 Tissue homogenizer Precellys24 is an efficient, robust and high throughput homogenizer, capable of simultaneously handling up to 24 samples. • High quality: robust, ergonomic and safe • Efficient: provides powerful 3D bead-beating while maintaining total molecular integrity • Flexible: from soft to hard tissues / from low to high throughput • Reproducible: more than a thousand validated protocols available for users +Compatible with the only patented and efficient cooling option for sensitive samples www.precellys.com 24x2ml
- 2. Efficient and robusthigh-throughput homogenizer PRECELLYS 24 Technical specifications The Science of Lysing CAPACITY from 1 to 24 tubes of 2ml/0,5ml SPEED RANGE 4000 – 6800 rpm by increment of 100rpm PROGRAMS 5 presets programs NUMBER OF CYCLES from 1 to 3 cycles TIME time of use per cycle: from 5s to 90s pause between cycle: from 5s to 120s SIZE L: 290mm, W: 375mm, H: 370mm (600mm with opened lid) WEIGHT 29,8 kg NORMS CE, FCC part 15 developed to be used in L3 laboratory ELECTRICITY 100 - 230 VAC / 50-60 Hz power:1 kVA NOISE ‹ 70dB PATENTED TECHNOLOGY CATALOG NUMBER 03119.200.RD000 Precellys range Discover the other products of the Precellys range Preserve your sensitive samples: ensure the combined yield and integrity of thermo-sensitive molecules by using the Cryolys cooling option! Precellys 24-Dual for flexibility Cryolys for sensitive samples Minilys for personal use Lysing Kits consumables ANIMAL HUMAN MICRO-ORGANISMS PLANT TISSUES Precellys 24 for high throughput Grind and homogenize a wide range of biological samples with Precellys 24! Designed for use inL3laboratories, it is highlyrobustfordailyuse. The system enables the preparation of upto24biological samples from soft to hard tissue (animal human tissue, plant tissue, microorganisms…) and has been validated on more than 1000 different samples: from brain, muscle and heart samples to very hard matter such as bones, hair and rice… A figure-of-8 multi-directional motion gives a high energy level to the beads that grind up to 24 samples together in just a few seconds, at speeds ranging from 4000 rpm to 6800 rpm. Typical homogenization time is thus around 30 seconds. Samples are then ready for analysis using DNA, RNA analysis, PCR, Electrophoresis, Liquid Chromatography, Western Blot… Precellys 24 - Quick User Mode 1. Load from one to twenty-four 2ml tubes 2. Position the patented system for quick and safe blocking 3. Set speed (4000 - 6800 rpm), time and cycle DNA RNA Drugs Proteins 4. 3D bead-beating: homogenization is achieved in just a few seconds 5. The same efficiency in each tube enables the liberation of cell components 6. In around 30 seconds, your sample is ready for analysis! Precellys24-February2012-DesignbyCCECie-Créditphotos:JPLagiewski 1000 protocols available on www.precellys.com BERTIN TECHNOLOGIES BERTIN Corp. FRANCE MD, USA Phone: +33 139 306 169 Phone: +1 240 428 1047 precellys@bertin.fr Find your distributor on www.precellys.com
- 3. • Dual: 6x7mlor 12x2 (or 0,5ml) lysing tubes • Flexible: from 0,5µl to 7ml samples / from soft to hard tissues • Efficient: provides powerful 3D bead-beating motion while maintaining total molecular integrity • High quality: robust, ergonomic and safe +Compatible with the only patented and efficient cooling option for sensitive samples www.precellys.com 6x7ml or 12x2ml Tissue homogenizer Precellys 24-Dual is an efficient flexible tissue homogenizer, for medium-to-high-throughput routine process. Precellys 24 Dual
- 4. Technical specifications CAPACITY from 1to 12 tubes of 2ml/0,5ml from 1 to 6 tubes of 7ml SPEED RANGE 4000 - 6500 rpm by increment of 100rpm PROGRAMS 5 user presets NUMBER OF CYCLES from 1 to 3 cycles TIME time of use per cycle: from 5s to 90s pause between cycle: from 5s to 120s SIZE L: 290mm, W: 375mm, H: 370mm (600mm with opened lid) WEIGHT 29,8 kg NORMS CE, FCC part 15 developed to be used in L3 laboratory ELECTRICITY 100 - 230 VAC / 50-60 Hz power:1 kVA NOISE ‹ 70dB PATENTED TECHNOLOGY CATALOG NUMBER 03119.200.RD010 Efficient and flexible homogenizer The Science of Lysing Precellys 24-Dual for greater flexibility Expand your Precellys 24 experience with the access to 7ml lysing tubes with Precellys 24-Dual! Precellys 24-Dual is a biological sample homogenizer for medium throughput (up to 12 samples) and a diverse range of biological samples (several different tube formats according to the size and quantity of your samples). The system enables sample preparation in 0.5ml, 2ml or 7ml tubes and biological samples from soft to hard tissues / from 1mg to 5000 mg. A figure-of-8 multi-directional motion gives a high energy level to the beads that grind up to 12 samples together in just a few seconds, at speeds ranging from 4000 to 6500 rpm. Typical homogenization time is thus around 30 seconds. Samples are then ready for analysis using DNA, RNA analysis, PCR, Electrophoresis, Liquid Chromatography, Western Blot… Precellys range Discover the other products of the Precellys range Preserve your sensitive samples: ensure the combined yield and integrity of thermo-sensitive molecules by using the Cryolys cooling option! PRECELLYS 24-DUAL Precellys 24 for high throughput Cryolys for sensitive samples Minilys for personal use Lysing Kits consumables Precellys 24-Dual - Quick User Mode DNA RNA Drugs Proteins 1. Load from one to twelve 2ml tubes or from one to six 7ml tubes 4. 3D bead-beating: homogenization is achieved in just a few seconds 2. Position the patented system for quick and safe blocking 5. The same efficiency in each tube enables the liberation of cell components 3. Set speed (4000 - 6500 rpm), time and cycle 6. In around 30 seconds, your sample is ready for analysis! Precellys24-Dual-February2012-DesignbyCCECie-Créditphotos:JPLagiewski 1000 protocols available on www.precellys.com BERTIN TECHNOLOGIES BERTIN Corp. FRANCE MD, USA Phone: +33 139 306 169 Phone: +1 240 428 1047 precellys@bertin.fr Find your distributor on www.precellys.com
- 5. • The onlyefficient and small homogenizer for 3D bead beating • Flexible ready-to-use: a wide range of samples (type/volume) and parameters • Convenient for personal use • Safe easy-to-handle system • Small equipment footprint www.precellys.com 1x7ml or 3x2ml Minilys is a flexible and personal homogenizer for cell/sample disruption for daily lab workflow. Minilys Tissue homogenizer
- 6. Technicalspecifications CAPACITY from 1 to3 tubes of 2ml/0,5ml from 1 to 3 microtubes 1 tube of 7ml SPEED RANGE 3000, 4000 or 5000 rpm TIME from 5s to 240s SIZE L: 180mm, W: 290mm, H: 380mm WEIGHT 7.8kg NORMS CE, FCC part 15 ELECTRICITY 100 - 230 VAC / 50-60 Hz power:1 kVA NOISE ‹ 70dB PATENTED TECHNOLOGY CATALOG NUMBER 06404.200.RD000 Flexible and personal homogenizer The Science of Lysing MINILYS Minilys is a small and compact homogenizer for fast hands-free disruption of a wide range of biological samples (prior to DNA, RNA, proteins or drug extraction) at a low throughput level. Flexible (0.5ml, 2ml, 7ml lysing tubes) and easy to handle, it is the only small homogenizer that works in 3D motion, following standard protocols and providing more homogeneous results. Moreover, Minilys is extremely budget-friendly. Convenient for personal use Specially designed for low-throughput laboratory workflows and personal use, Minilys homogenizes 3 samples simultaneously in 0.5ml/2ml tubes or 1 sample in 7ml. Small and compact, Minilys requires minimal bench space in your laboratory. Efficient rapid Minilys offers the same bead-beating technology and extremely high quality as the Precellys homogenizer range, is the only small homogenizer on the market that disrupts samples using 3D motion and is by far the most efficient one. Safe easy-handling Minilys ensures easy-handling and safe operations. Its innovative cut-out system automatically stops the operation if the lid is not firmly closed or is opened while running, thus providing additional safety guarantees for users. Flexible ready-to-use Minilys accommodates a widerangeofsampletypes from animal plant tissue to microorganisms. With 3 different speeds ranging from 3000 to 5000 rpm, Minilys can handle either low- velocity agitation or harsh homogenization. Detachable tube-holders are adapted to three volumes of lysing tubes (0,5ml, 2ml or 7ml), providing the flexibility to vary your sample size and volume. Precellys range Discover the other products of the Precellys range MINILYS Precellys 24 for high throughput Precellys 24-Dual for flexibility Cryolys for sensitive samples Lysing Kits consumables Minilys - Quick User Mode 1. Prepare your biological samples in 0.5, 2ml or 7ml tubes 2. Load between one and three 2ml or 7ml tubes 5. In around 30 seconds, your sample is ready for analysis! 3. Set speed and time 4. 3D beat-beating: same efficiency in each tube enables the liberation of cell components. Minilys-February2012-February2012-DesignbyCCECie-Créditphotos:JPLagiewski 1000 protocols available on www.precellys.com BERTIN TECHNOLOGIES BERTIN Corp. FRANCE MD, USA Phone: +33 139 306 169 Phone: +1 240 428 1047 precellys@bertin.fr Find your distributor on www.precellys.com
- 7. • Efficient cooling:before, during and after processing • Ideal for thermo-sensitive molecules: RNA, siRNA, metabolites, enzymes, proteins… • Adjustable cooling flow rate • Powered by liquid nitrogen or dry ice www.precellys.com Cooling system for sensitive sample preparation C ryolys coupled with Precell ys Cryolysisapatentedcoolingoption to overcome the heat limitations of regular grinding and to protect thermo-sensitive molecules Cryolys
- 8. Technical specifications AIR FLOWRATE SETTINGS 80, 100 or 120 litre/min SIZE L: 430mm, W: 300mm, H: 300mm WEIGHT 16 kg NORMS CE ELECTRICITY 100 - 230 VAC / 50-60 Hz power: 2A NOISE ‹ 70dB PATENTED TECHNOLOGY Lab requirement Compressed air (lab network or canister): - Pressure: from 4 bars (5 PSI) to 8 bars (116 PSI) - Flow rate: up to 120 l/min (7,2 m3/h) - Consumption (run time): 1l of liquid nitrogen for 5 min / 1kg of dry ice for 1,5h CATALOG NUMBER 05068.200.RD000 Cooling system for sensitive sample preparation The Science of Lysing CRYOLYS for sensitive samples Cryolys is the only patented cooling option that prevents the increase of temperature during lysing; it thus enhances the efficiency of molecular extraction, resulting in premium quality analysis, maintaining temperature at approximately 4°C before and during homogenization. It enables the extraction of stable RNA and native-state proteins. Cryolys is compatible with Precellys 24 and Precellys 24-Dual homogenizers. Cold air (-50°C) is sprayed around each tube so that the temperature during homogenization remains at around 4°C. A probe enables real-time monitoring of the temperature inside the lid, thus protecting sensitive molecules from degradation during sample preparation. Achieve higher yield, greater quality and increased functionality Prevent enzymes from becoming active Retain 100% active proteins Precellys range Discover the other products of the Precellys range Cryolys - Quick User Mode CRYOLYS Precellys 24 for high throughput Precellys 24-Dual for flexibility Minilys for personal use Lysing Kits consumables Temp. in tubes Temp. in tube w/Cryolys Precellys Run on/Off Temperature Profile with Cryolys Option 6800rpm, 3x30s, 30s breaks, Compressed Air Flow rate: 120L/min Température(C°) 90 80 70 60 50 40 30 20 10 0 0 0,5 1 1,5 2 2,5 3 3,5 4 Time (min) +85°C inside tubes without Cryolys With Cryolys, your sensitive samples are preserved ! 1.Compressed air passes through liquid nitrogen or dry-ice inside Cryolys 2. Cold compressed air is sprayed into the specially-adapted Precellys lid 3. Each sample is cooled and temperature sensitive molecules are retained in their native state Cryolys-February2012-DesignbyCCECie-Créditphotos:JPLagiewski 1000 protocols available on www.precellys.com BERTIN TECHNOLOGIES BERTIN Corp. FRANCE MD, USA Phone: +33 139 306 169 Phone: +1 240 428 1047 precellys@bertin.fr Find your distributor on www.precellys.com
- 9. • More than15 references for soft samples to hard samples • 0,5ml – 2ml – 7ml ready-to-use tubes • Wide range and mix of beads for optimized results • Full range of ceramic beads www.precellys.com 0,5ml tubes 2ml tubes 7ml tubes Precellys Lysing Kits are prefilled tubes with specific beads and are suitable for use with all biological samples prepared for DNA, RNA, protein or drug extraction. Precellys Lysing kits for tissue homogenizer 1000 protocols available on www.precellys.com
- 10. Animal and Humantissue homogenization Brain, liver, heart, muscle, skin, kidney, lung, spleen, colon, faeces etc. Also pulverization of difficult tissue samples such as bones, hair, cartilage, etc. Whole organs can even be prepared thanks to 7ml Lysing Kits. Plant tissue grinding Leaves oats, tomato seeds, cotton, soil etc. Also pulverization of hard materials such as seeds, roots, rice etc. Large samples can also be prepared thanks to 7ml Lysing Kits. Micro-organism lysing Small beads facilitate the crushing of micro-organism walls. Yeast, fungi, spores, mould, bact. gram+/gram-, mycobacteria, cyanobacteria, algae etc. 0.5ml Lysing Kits are especially suited to small sample amounts. Technical specifications QUANTITY OF TUBES PER KIT: 50 TUBES CAPS MATERIALS: Polypropylen Co-Polymered TEMPERATURE RANGE OF USE: -80°C to 100°C AUTOCLAVE: standard procedure CHEMICAL COMPATIBILITY: compatible with most of extraction buffer (Acid Phenol, Guanidine thiocyanate, acetonitril etc.) LOADING CAPACITY 0.5ml : from 1mg to 30mg tissue or 5µL to 200µL culture LOADING CAPACITY 2ml : from 30mg to 1g tissue or 200µL to 1.6ml culture LOADING CAPACITY 7ml : from 30mg to 5g tissue or 200µL to 6ml culture COMPATIBLE WITH PRECELLYS 24, PRECELLYS 24-DUAL, CRYOLYS AND MINILYS. A complete range for biological samples preparation PRECELLYS LYSING KITS The Science of Lysing Enjoy all the benefits of Precellys’ powerful bead-beating technology with the 15 available references of Precellys Lysing Kits! Precellys Lysing Kits are robust tubes prefilled with high quality beads and manufactured under clean-room environment. Optimize your preparation of biological samples: animal tissue, human tissue, plant tissue, microorganisms… whatever the precious sample you wish to prepare, find a suitable Precellys Lysing kit from the 15 available references: choose the right tube size (0.5ml, 2ml or 7ml), bead type / diameter (ceramic, glass, stainless steel …) and you will be sure to obtain excellent DNA, RNA, Protein and Drug recovery! Log on now to www.precellys.com to find the most suitable lysing kit for your sample! Save time and improve your lab practices by following tried tested scientific publications: use our web-based Application Center to find the right Lysing Kit for your sample: just enter your sample name and get access to examples, lysing kits and protocols that current Precellys’ users are already using! Precellys 24 for high throughput Precellys 24-Dual for flexibility Cryolys for sensitive sample Minilys for personal use Precellys range Precellys Lysing Kits are specially designed for use with the entire Precellys range: Precellyslysingkits-February2012-DesignbyCCECie-Créditphotos:JPLagiewski Precellys LYSING KITS 1000 protocols available on www.precellys.com BERTIN TECHNOLOGIES BERTIN Corp. FRANCE MD, USA Phone: +33 139 306 169 Phone: +1 240 428 1047 precellys@bertin.fr Find your distributor on www.precellys.com