The HT Homogenizer is a high throughput sample disruption device that processes samples in microwell plates, deep well plates, microfuge tubes, and vial sets using linear motion to homogenize samples quickly and consistently. It is a small but powerful homogenizer that can disrupt hard tissues and matrices like corn kernels, bone, and fibrous tissues at speeds from 50 to 1600 cycles per minute. It is useful for individual and pooled sample preparation in applications like DNA, RNA, and protein isolation from animal and plant tissues and microorganisms.