SlideShare a Scribd company logo
3/28/20171
Prof: Kavitha Mole PJ
3/28/2017
2
INTRODUCTION
3/28/20173
DEFINITION
DEFINITION:
Preeclampsia is a multiple system disorder of unknown etiology
characterized by development of hypertension to the extent of 140/90
mm hg or more with proteinuria after 20th week in a previously
normotensive and non-proteinuric woman.
PREGNANCY INDUCED HYPERTENSION :
The term “pregnancy induced hypertension (PIH)” is defined
as the hypertension that develops as a direct result of a gravid state.
It includes
 Gestational hypertension
 Pre-eclampsia
 Eclampsia
3/28/20174
DIAGNOSTIC CRITERIA OF
PREECLAMPSIA
3/28/20175
RISK FACTORS
 Primigravida
 Family history
 Placental
abnormalities
 Obesity
 Pre-existing
vascular disease
 New paternity
 Thrombophilias
3/28/20176
PATHOPHYSIOLOGY
3/28/20177
In normal pregnancy
 Angiotensin II is destroyed by angiotensinase enzyme
which is liberated from placenta.
 Vascular system becomes refraction to pressure agent like
angiotensin II by increased synthesis of prostaglandin and
nitric oxide, which act as vasodilator.
CLINICAL TYPES
PRE-ECLAMPSIA
MILD SEVERE
 Diastolic BP is above 90 mm
hg but less than 110 mm hg.
 Systolic BP is 30 mm hg above
the pregnancy reading in early
pregnancy.
 The mean arterial pressure
exceeds 105 mm hg.
 Systolic BP more than 160mm hg
or diastolic more than 110 mm hg.
 Proteinuria > 5 gm/24 hours.
 Oliguria < 400 ml/24 hours.
 Platelet count < 100000 / mm3.
 HELLP syndrome.
 Cerebral or visual disturbances.
 IUGR
3/28/20178
CLINICAL FEATURES
PRE-ECLAMPSIA
WARNING SIGNS SIGNS
 Severe headache or blurred vision
 Nausea or vomiting
 Dizziness or double vision
 Excessive swelling of the hands or feet
 Decreased frequency of urination
 Rapid pulse
 Abnormal weight gain
 Raise blood pressure
 Oedema
 Pulmonary oedema
ALARMING SYMPTOMSMILD SYMPTOMS
 Slight swelling over the ankles.
 Swelling may extend to face,
abdominal wall, vulva and even the
whole body.
 Headache
 Diminished urine output.
 Disturbed sleep.
 Epigastric pain.
 Eye symptoms
 Blurring vision
3/28/20179
INVESTIGATION
3/28/201710
CONT…..
3/28/201711
COMPLICATIONS
IMMEDIATE
Maternal complication
During pregnancy
 Eclampsia
 Accidental hemorrhage
 Oliguria and anuria
 Preterm labour
 HELLP syndrome
 Dimness of vision and even blindness
 Cerebral hemorrhage
 Acute respiratory distress syndrome (ARDS)
3/28/201712
CONT…..
During labour
 Eclampsia
 Postpartum hemorrhage
Puerperium
 Eclampsia
 Shock
 Sepsis.
Fetal complications
 Intrauterine death
 Asphyxia
 Prematurity
 IUGR
Remote complications
 Residual hypertension
 Recurrent pre-eclampsia
 Chronic renal disease
 Placental abruption
3/28/201713
SCREENING TESTS
 Doppler ultrasound
 Presence of diastolic notch at 24 weeks gestation.
 Absence of end diastolic frequencies.
 Average mean arterial pressure (MAP) in second
trimester more than 90 mm hg.
 Fetal DNA.
3/28/201714
PROPHYLACTIC MEASURES
 Regular antenatal check-up.
 Antithrombotic agents.
 Heparin or low molecular weight.
 Calcium supplementation (2 gms per day).
 Antioxidants, vitamins E, C, and nutritional
supplementation with magnesium, zinc, fish oil and
low salt diet.
 Balanced diet.
3/28/201715
MANAGEMENT
Objectives
 To stabilize the hypertension and to prevent severe
pre-eclampsia.
 To prevent the complications.
 To prevent eclampsia.
 Delivery a healthy baby in optimal time.
 Restoration of the health of the mother in
Puerperium.
3/28/201716
HOSPITAL MANAGEMENT
• REST
DIET
3/28/201717
CONT…..
 DIURETICS
 ANTIHYPERTENSIVE
DRUG
3/28/201718
CONT…..
DRUGS DOSE SCHEDULE MAXIMUM DOSE MAINTAINANCE DOSE
Labetalol 10-20 mg, IV every
10 min
300 mg, IV 40 mg/hour
Hydralazine 5 mg, IV every 30
min
30 mg, IV 10 mg/ hour
Nifedipine 10-20 mg, orally,
can be repeated in
30 min
240 mg/ 24 hour 4-6 hour interval
Nitroglycerine 5 µg/ min IV Short term therapy only when the other drugs
have failed.Sodium
Nitroprusside
0.25-5 µg/kg/min
IV
Antihypertensive crisis
The following drugs can be used when the BP is more than 160/110 mm hg
or the MAP is more than 125 mm hg :
3/28/201719
CONT…..
MANAGEMENT
DURATION OF
TREATMENT
GROUP-
A
METHODS OF
DELIVERY
INDUCTION OF
LABOUR
CAESAREAN
SECTION
GROUP-
B
GROUP-
C
3/28/201720
CONT…..
Management during labour
 Progress of labour recorded in partograph.
 Abdominal and vaginal examination at regular
intervals.
 Bed rest in first stage of labour.
 Cut short the second stage of labour with using
prophylactic forceps.
 Methergine contraindicated in 3rd stage.
3/28/201721
SCHEME OF MANAGEMENT OF PRE- ECLAMPSIA
3/28/201722
HEELLP SYNDROME
 This is an acronym for haemolysis, elevated liver
enzymes and low platelet count (< 100000 mm3).
 This is rare complications in pre-eclampsia.
 HELLP syndrome are developed even without
maternal hypertension.
 The symptoms are nausea, vomiting, Epigastric pain,
right upper quadrant pain along with biochemical and
hematological changes.
 There may be sub capsular hematoma formation and
peripheral blood smear.
3/28/201723
 Antiseizure prophylaxis with magnesium sulphate
(MgSO4) are started.
 Anticorticosteroids administer to improves the perineal and
maternal outcome.
 Caesarean section are common mode of delivery.
 Epidural anaesthesia can be used very safely if platelet
count more than 100000 /mm3.
 Platelet transfusion if count less than 50,000/mm3.
 Recurrent risk of HELLP syndrome 3-19 %.
3/28/201724
CONT…..
Expectant management
 This management carried out selectively :
 When pregnancy less than 34 weeks.
 With bed rest.
 Plasma volume expansion.
 Antithrombotic agent (Dipyridamole).
 Anti-immunosuppressant (steroids).
 Others (fresh frozen plasma).
3/28/201725
 Abruptio placentae
 Cerebral oedema
 Pulmonary oedema
 Laryngeal oedema
 ARDS
 Sepsis
 Acute renal failure
 Severe ascites
 Retinal detachment
 Subcapsular hematoma
 Death
3/28/201726
3/28/201727
3/28/201728
3/28/201729

More Related Content

What's hot

Premature labour
Premature labourPremature labour
Premature labour
Balkeej Sidhu
 
Hydatidiform Mole
Hydatidiform MoleHydatidiform Mole
Hydatidiform Mole
Sandhya Kumari
 
Eclampsia ppt
Eclampsia pptEclampsia ppt
Eclampsia ppt
Abhilasha verma
 
Caesarean section
Caesarean sectionCaesarean section
Caesarean section
Snehlata Parashar
 
Hyperemesis gravidarum
Hyperemesis gravidarumHyperemesis gravidarum
Hyperemesis gravidarum
jagadeeswari jayaseelan
 
Prolonged labour
Prolonged labourProlonged labour
Prolonged labour
Priyanka Gohil
 
Normal labour
Normal labourNormal labour
Normal labour
Priyanka Gohil
 
PUERPERAL SEPSIS
PUERPERAL SEPSISPUERPERAL SEPSIS
PUERPERAL SEPSIS
TriptiSharma72
 
Partograph
PartographPartograph
Partograph
Shrooti Shah
 
Hydatidiform (vesicular) mole
Hydatidiform (vesicular) moleHydatidiform (vesicular) mole
Hydatidiform (vesicular) moleraj kumar
 
Breech presentation
Breech presentationBreech presentation
Breech presentation
Ayman Shehata
 
Episiotomy
EpisiotomyEpisiotomy
Episiotomy
Shrooti Shah
 
Rupture of the uterus
Rupture of the uterusRupture of the uterus
Rupture of the uterusFahad Zakwan
 
HYPEREMESIS GRAVIDARUM
HYPEREMESIS GRAVIDARUMHYPEREMESIS GRAVIDARUM
HYPEREMESIS GRAVIDARUM
Arkab Khan Pathan
 
Abruptio placentae
Abruptio placentae Abruptio placentae
Abruptio placentae
Shailendra Veerarajapura
 
ECLAMPSIA
ECLAMPSIAECLAMPSIA
Physiological changes during pregnancy
Physiological changes during pregnancyPhysiological changes during pregnancy
Physiological changes during pregnancyvruti patel
 

What's hot (20)

Premature labour
Premature labourPremature labour
Premature labour
 
Hydatidiform Mole
Hydatidiform MoleHydatidiform Mole
Hydatidiform Mole
 
Eclampsia ppt
Eclampsia pptEclampsia ppt
Eclampsia ppt
 
Caesarean section
Caesarean sectionCaesarean section
Caesarean section
 
Hyperemesis gravidarum
Hyperemesis gravidarumHyperemesis gravidarum
Hyperemesis gravidarum
 
hydatidiform mole
hydatidiform molehydatidiform mole
hydatidiform mole
 
Prolonged labour
Prolonged labourProlonged labour
Prolonged labour
 
Normal labour
Normal labourNormal labour
Normal labour
 
Threatened abortion
Threatened abortion Threatened abortion
Threatened abortion
 
PUERPERAL SEPSIS
PUERPERAL SEPSISPUERPERAL SEPSIS
PUERPERAL SEPSIS
 
Partograph
PartographPartograph
Partograph
 
Hydatidiform (vesicular) mole
Hydatidiform (vesicular) moleHydatidiform (vesicular) mole
Hydatidiform (vesicular) mole
 
Breech presentation
Breech presentationBreech presentation
Breech presentation
 
Episiotomy
EpisiotomyEpisiotomy
Episiotomy
 
Rupture of the uterus
Rupture of the uterusRupture of the uterus
Rupture of the uterus
 
HYPEREMESIS GRAVIDARUM
HYPEREMESIS GRAVIDARUMHYPEREMESIS GRAVIDARUM
HYPEREMESIS GRAVIDARUM
 
Abruptio placentae
Abruptio placentae Abruptio placentae
Abruptio placentae
 
ECLAMPSIA
ECLAMPSIAECLAMPSIA
ECLAMPSIA
 
puerperium
puerperiumpuerperium
puerperium
 
Physiological changes during pregnancy
Physiological changes during pregnancyPhysiological changes during pregnancy
Physiological changes during pregnancy
 

Viewers also liked

Case Study Report on PIH and Severe Pre eclampsia
Case Study Report on PIH and Severe Pre eclampsiaCase Study Report on PIH and Severe Pre eclampsia
Case Study Report on PIH and Severe Pre eclampsia
Rashmi Regmi
 
eclampsia presentation
eclampsia presentationeclampsia presentation
eclampsia presentation
Kavitha Kaleshan
 
Pre Eclampsia Powerpoint Template - SlideWorld
Pre Eclampsia Powerpoint Template -  SlideWorldPre Eclampsia Powerpoint Template -  SlideWorld
Pre Eclampsia Powerpoint Template - SlideWorld
http://www.slideworld.com/
 
Pre-Eclampsia & Eclampsia
Pre-Eclampsia & EclampsiaPre-Eclampsia & Eclampsia
Pre-Eclampsia & Eclampsia
limgengyan
 
Pre eclampsia; eclampsia
Pre eclampsia; eclampsiaPre eclampsia; eclampsia
Pre eclampsia; eclampsiaEddo Adams
 
Preeclampsia
PreeclampsiaPreeclampsia
Preeclampsia
Androu Waheeb
 
Preeclampsia 2015
Preeclampsia 2015Preeclampsia 2015
Preeclampsia 2015
Gladys Maria Lovo Caballero
 
Pre eclampsia & eclampsia
Pre eclampsia & eclampsiaPre eclampsia & eclampsia
Pre eclampsia & eclampsia
shanza aurooj
 
Preeclampsia Y Eclampsia
Preeclampsia Y EclampsiaPreeclampsia Y Eclampsia
Preeclampsia Y EclampsiaSandra Gallaga
 

Viewers also liked (10)

Case Study Report on PIH and Severe Pre eclampsia
Case Study Report on PIH and Severe Pre eclampsiaCase Study Report on PIH and Severe Pre eclampsia
Case Study Report on PIH and Severe Pre eclampsia
 
eclampsia presentation
eclampsia presentationeclampsia presentation
eclampsia presentation
 
Pre Eclampsia Powerpoint Template - SlideWorld
Pre Eclampsia Powerpoint Template -  SlideWorldPre Eclampsia Powerpoint Template -  SlideWorld
Pre Eclampsia Powerpoint Template - SlideWorld
 
Pre-Eclampsia & Eclampsia
Pre-Eclampsia & EclampsiaPre-Eclampsia & Eclampsia
Pre-Eclampsia & Eclampsia
 
Pre eclampsia; eclampsia
Pre eclampsia; eclampsiaPre eclampsia; eclampsia
Pre eclampsia; eclampsia
 
Pre eclampsia
Pre eclampsiaPre eclampsia
Pre eclampsia
 
Preeclampsia
PreeclampsiaPreeclampsia
Preeclampsia
 
Preeclampsia 2015
Preeclampsia 2015Preeclampsia 2015
Preeclampsia 2015
 
Pre eclampsia & eclampsia
Pre eclampsia & eclampsiaPre eclampsia & eclampsia
Pre eclampsia & eclampsia
 
Preeclampsia Y Eclampsia
Preeclampsia Y EclampsiaPreeclampsia Y Eclampsia
Preeclampsia Y Eclampsia
 

Similar to PRE -ECLAMPSIA

pptonpre-ecautosaved-170328035747 (1).pptx
pptonpre-ecautosaved-170328035747 (1).pptxpptonpre-ecautosaved-170328035747 (1).pptx
pptonpre-ecautosaved-170328035747 (1).pptx
vijaymala00
 
Preeclampsia in pregnancy etiopathogenesis and management
Preeclampsia in pregnancy  etiopathogenesis and management Preeclampsia in pregnancy  etiopathogenesis and management
Preeclampsia in pregnancy etiopathogenesis and management
Deepti Daswani
 
Pih, by dr omer ajmal
Pih, by dr omer ajmalPih, by dr omer ajmal
Pih, by dr omer ajmal
Omer Ajmal
 
CIP.pptx
CIP.pptxCIP.pptx
CIP.pptx
Priyanka964777
 
Hypertensive disorders in pregnancy
Hypertensive disorders in pregnancyHypertensive disorders in pregnancy
Hypertensive disorders in pregnancy
gauriwaghamare1
 
HYPERTENSIVE DISORDERS IN PREGNANCY.pptx
HYPERTENSIVE DISORDERS IN PREGNANCY.pptxHYPERTENSIVE DISORDERS IN PREGNANCY.pptx
HYPERTENSIVE DISORDERS IN PREGNANCY.pptx
Gouri Das
 
Medical disorders in pregnancy
Medical disorders in pregnancyMedical disorders in pregnancy
Medical disorders in pregnancy
Awoke Worku
 
Hypertensive disorders in Pregnancy
Hypertensive disorders in PregnancyHypertensive disorders in Pregnancy
Hypertensive disorders in Pregnancy
Hanifullah Khan
 
Hypertensive disorders in pregnancy -I
Hypertensive disorders in pregnancy -IHypertensive disorders in pregnancy -I
Hypertensive disorders in pregnancy -I
obgymgmcri
 
PIH.pptx8888888888888888888888888888888888
PIH.pptx8888888888888888888888888888888888PIH.pptx8888888888888888888888888888888888
PIH.pptx8888888888888888888888888888888888
JamesAmaduKamara
 
Pregnancy induced hypertension
Pregnancy induced hypertensionPregnancy induced hypertension
Pregnancy induced hypertensionDeepa Sinha
 
Figeroa pih
Figeroa   pihFigeroa   pih
Figeroa pihfelling
 
Renal disorders in pregnancy
Renal disorders in pregnancyRenal disorders in pregnancy
Renal disorders in pregnancy
scienthiasanjeevani1
 
CME Hypertension in Pregnancy.pdf
CME Hypertension in Pregnancy.pdfCME Hypertension in Pregnancy.pdf
CME Hypertension in Pregnancy.pdf
yogeswary7
 
Hypertensive disorder in pregnancy .pptx
Hypertensive disorder in pregnancy .pptxHypertensive disorder in pregnancy .pptx
Hypertensive disorder in pregnancy .pptx
upendrakumar200509
 
Hypertension in pregnancy
Hypertension in pregnancyHypertension in pregnancy
Hypertension in pregnancy
Jackson Henerico
 
Lecture 16 Hypertensive disorders in pregnancy
Lecture 16 Hypertensive disorders in pregnancyLecture 16 Hypertensive disorders in pregnancy
Lecture 16 Hypertensive disorders in pregnancy
Public Health & Medical Academy
 
Htninpregnancy 130120114747-phpapp01
Htninpregnancy 130120114747-phpapp01Htninpregnancy 130120114747-phpapp01
Htninpregnancy 130120114747-phpapp01
Krupa Meet Patel
 
htninpregnancy-130120114747-phpapp01.pdf
htninpregnancy-130120114747-phpapp01.pdfhtninpregnancy-130120114747-phpapp01.pdf
htninpregnancy-130120114747-phpapp01.pdf
SavitaHanamsagar
 

Similar to PRE -ECLAMPSIA (20)

pptonpre-ecautosaved-170328035747 (1).pptx
pptonpre-ecautosaved-170328035747 (1).pptxpptonpre-ecautosaved-170328035747 (1).pptx
pptonpre-ecautosaved-170328035747 (1).pptx
 
Preeclampsia.pdf
Preeclampsia.pdfPreeclampsia.pdf
Preeclampsia.pdf
 
Preeclampsia in pregnancy etiopathogenesis and management
Preeclampsia in pregnancy  etiopathogenesis and management Preeclampsia in pregnancy  etiopathogenesis and management
Preeclampsia in pregnancy etiopathogenesis and management
 
Pih, by dr omer ajmal
Pih, by dr omer ajmalPih, by dr omer ajmal
Pih, by dr omer ajmal
 
CIP.pptx
CIP.pptxCIP.pptx
CIP.pptx
 
Hypertensive disorders in pregnancy
Hypertensive disorders in pregnancyHypertensive disorders in pregnancy
Hypertensive disorders in pregnancy
 
HYPERTENSIVE DISORDERS IN PREGNANCY.pptx
HYPERTENSIVE DISORDERS IN PREGNANCY.pptxHYPERTENSIVE DISORDERS IN PREGNANCY.pptx
HYPERTENSIVE DISORDERS IN PREGNANCY.pptx
 
Medical disorders in pregnancy
Medical disorders in pregnancyMedical disorders in pregnancy
Medical disorders in pregnancy
 
Hypertensive disorders in Pregnancy
Hypertensive disorders in PregnancyHypertensive disorders in Pregnancy
Hypertensive disorders in Pregnancy
 
Hypertensive disorders in pregnancy -I
Hypertensive disorders in pregnancy -IHypertensive disorders in pregnancy -I
Hypertensive disorders in pregnancy -I
 
PIH.pptx8888888888888888888888888888888888
PIH.pptx8888888888888888888888888888888888PIH.pptx8888888888888888888888888888888888
PIH.pptx8888888888888888888888888888888888
 
Pregnancy induced hypertension
Pregnancy induced hypertensionPregnancy induced hypertension
Pregnancy induced hypertension
 
Figeroa pih
Figeroa   pihFigeroa   pih
Figeroa pih
 
Renal disorders in pregnancy
Renal disorders in pregnancyRenal disorders in pregnancy
Renal disorders in pregnancy
 
CME Hypertension in Pregnancy.pdf
CME Hypertension in Pregnancy.pdfCME Hypertension in Pregnancy.pdf
CME Hypertension in Pregnancy.pdf
 
Hypertensive disorder in pregnancy .pptx
Hypertensive disorder in pregnancy .pptxHypertensive disorder in pregnancy .pptx
Hypertensive disorder in pregnancy .pptx
 
Hypertension in pregnancy
Hypertension in pregnancyHypertension in pregnancy
Hypertension in pregnancy
 
Lecture 16 Hypertensive disorders in pregnancy
Lecture 16 Hypertensive disorders in pregnancyLecture 16 Hypertensive disorders in pregnancy
Lecture 16 Hypertensive disorders in pregnancy
 
Htninpregnancy 130120114747-phpapp01
Htninpregnancy 130120114747-phpapp01Htninpregnancy 130120114747-phpapp01
Htninpregnancy 130120114747-phpapp01
 
htninpregnancy-130120114747-phpapp01.pdf
htninpregnancy-130120114747-phpapp01.pdfhtninpregnancy-130120114747-phpapp01.pdf
htninpregnancy-130120114747-phpapp01.pdf
 

Recently uploaded

Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondEmpowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Health Catalyst
 
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
pchutichetpong
 
POLYCYSTIC OVARIAN SYNDROME (PCOS)......
POLYCYSTIC OVARIAN SYNDROME (PCOS)......POLYCYSTIC OVARIAN SYNDROME (PCOS)......
POLYCYSTIC OVARIAN SYNDROME (PCOS)......
Ameena Kadar
 
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfCHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
Sachin Sharma
 
ABDOMINAL COMPARTMENT SYSNDROME
ABDOMINAL COMPARTMENT SYSNDROMEABDOMINAL COMPARTMENT SYSNDROME
ABDOMINAL COMPARTMENT SYSNDROME
Rommel Luis III Israel
 
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
Kumar Satyam
 
HEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptxHEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptx
priyabhojwani1200
 
The Docs PPG - 30.05.2024.pptx..........
The Docs PPG - 30.05.2024.pptx..........The Docs PPG - 30.05.2024.pptx..........
The Docs PPG - 30.05.2024.pptx..........
TheDocs
 
Nursing Care of Client With Acute And Chronic Renal Failure.ppt
Nursing Care of Client With Acute And Chronic Renal Failure.pptNursing Care of Client With Acute And Chronic Renal Failure.ppt
Nursing Care of Client With Acute And Chronic Renal Failure.ppt
Rommel Luis III Israel
 
A Community health , health for prisoners
A Community health  , health for prisonersA Community health  , health for prisoners
A Community health , health for prisoners
Ahmed Elmi
 
BOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptx
BOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptxBOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptx
BOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptx
AnushriSrivastav
 
The Impact of Meeting: How It Can Change Your Life
The Impact of Meeting: How It Can Change Your LifeThe Impact of Meeting: How It Can Change Your Life
The Impact of Meeting: How It Can Change Your Life
ranishasharma67
 
Neuro Saphirex Cranial Brochure
Neuro Saphirex Cranial BrochureNeuro Saphirex Cranial Brochure
Neuro Saphirex Cranial Brochure
RXOOM Healthcare Pvt. Ltd. ​
 
CONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docxCONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docx
PGIMS Rohtak
 
10 Ideas for Enhancing Your Meeting Experience
10 Ideas for Enhancing Your Meeting Experience10 Ideas for Enhancing Your Meeting Experience
10 Ideas for Enhancing Your Meeting Experience
ranishasharma67
 
The Importance of Community Nursing Care.pdf
The Importance of Community Nursing Care.pdfThe Importance of Community Nursing Care.pdf
The Importance of Community Nursing Care.pdf
AD Healthcare
 
Yemen National Tuberculosis Program .ppt
Yemen National Tuberculosis Program .pptYemen National Tuberculosis Program .ppt
Yemen National Tuberculosis Program .ppt
Esam43
 
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
ranishasharma67
 
Roti bank chennai PPT [Autosaved].pptx1
Roti bank  chennai PPT [Autosaved].pptx1Roti bank  chennai PPT [Autosaved].pptx1
Roti bank chennai PPT [Autosaved].pptx1
roti bank
 
Navigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and BeyondNavigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and Beyond
Aboud Health Group
 

Recently uploaded (20)

Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondEmpowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
 
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
 
POLYCYSTIC OVARIAN SYNDROME (PCOS)......
POLYCYSTIC OVARIAN SYNDROME (PCOS)......POLYCYSTIC OVARIAN SYNDROME (PCOS)......
POLYCYSTIC OVARIAN SYNDROME (PCOS)......
 
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfCHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
 
ABDOMINAL COMPARTMENT SYSNDROME
ABDOMINAL COMPARTMENT SYSNDROMEABDOMINAL COMPARTMENT SYSNDROME
ABDOMINAL COMPARTMENT SYSNDROME
 
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
 
HEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptxHEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptx
 
The Docs PPG - 30.05.2024.pptx..........
The Docs PPG - 30.05.2024.pptx..........The Docs PPG - 30.05.2024.pptx..........
The Docs PPG - 30.05.2024.pptx..........
 
Nursing Care of Client With Acute And Chronic Renal Failure.ppt
Nursing Care of Client With Acute And Chronic Renal Failure.pptNursing Care of Client With Acute And Chronic Renal Failure.ppt
Nursing Care of Client With Acute And Chronic Renal Failure.ppt
 
A Community health , health for prisoners
A Community health  , health for prisonersA Community health  , health for prisoners
A Community health , health for prisoners
 
BOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptx
BOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptxBOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptx
BOWEL ELIMINATION BY ANUSHRI SRIVASTAVA.pptx
 
The Impact of Meeting: How It Can Change Your Life
The Impact of Meeting: How It Can Change Your LifeThe Impact of Meeting: How It Can Change Your Life
The Impact of Meeting: How It Can Change Your Life
 
Neuro Saphirex Cranial Brochure
Neuro Saphirex Cranial BrochureNeuro Saphirex Cranial Brochure
Neuro Saphirex Cranial Brochure
 
CONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docxCONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docx
 
10 Ideas for Enhancing Your Meeting Experience
10 Ideas for Enhancing Your Meeting Experience10 Ideas for Enhancing Your Meeting Experience
10 Ideas for Enhancing Your Meeting Experience
 
The Importance of Community Nursing Care.pdf
The Importance of Community Nursing Care.pdfThe Importance of Community Nursing Care.pdf
The Importance of Community Nursing Care.pdf
 
Yemen National Tuberculosis Program .ppt
Yemen National Tuberculosis Program .pptYemen National Tuberculosis Program .ppt
Yemen National Tuberculosis Program .ppt
 
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
 
Roti bank chennai PPT [Autosaved].pptx1
Roti bank  chennai PPT [Autosaved].pptx1Roti bank  chennai PPT [Autosaved].pptx1
Roti bank chennai PPT [Autosaved].pptx1
 
Navigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and BeyondNavigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and Beyond
 

PRE -ECLAMPSIA

  • 2. Prof: Kavitha Mole PJ 3/28/2017 2
  • 4. DEFINITION DEFINITION: Preeclampsia is a multiple system disorder of unknown etiology characterized by development of hypertension to the extent of 140/90 mm hg or more with proteinuria after 20th week in a previously normotensive and non-proteinuric woman. PREGNANCY INDUCED HYPERTENSION : The term “pregnancy induced hypertension (PIH)” is defined as the hypertension that develops as a direct result of a gravid state. It includes  Gestational hypertension  Pre-eclampsia  Eclampsia 3/28/20174
  • 6. RISK FACTORS  Primigravida  Family history  Placental abnormalities  Obesity  Pre-existing vascular disease  New paternity  Thrombophilias 3/28/20176
  • 7. PATHOPHYSIOLOGY 3/28/20177 In normal pregnancy  Angiotensin II is destroyed by angiotensinase enzyme which is liberated from placenta.  Vascular system becomes refraction to pressure agent like angiotensin II by increased synthesis of prostaglandin and nitric oxide, which act as vasodilator.
  • 8. CLINICAL TYPES PRE-ECLAMPSIA MILD SEVERE  Diastolic BP is above 90 mm hg but less than 110 mm hg.  Systolic BP is 30 mm hg above the pregnancy reading in early pregnancy.  The mean arterial pressure exceeds 105 mm hg.  Systolic BP more than 160mm hg or diastolic more than 110 mm hg.  Proteinuria > 5 gm/24 hours.  Oliguria < 400 ml/24 hours.  Platelet count < 100000 / mm3.  HELLP syndrome.  Cerebral or visual disturbances.  IUGR 3/28/20178
  • 9. CLINICAL FEATURES PRE-ECLAMPSIA WARNING SIGNS SIGNS  Severe headache or blurred vision  Nausea or vomiting  Dizziness or double vision  Excessive swelling of the hands or feet  Decreased frequency of urination  Rapid pulse  Abnormal weight gain  Raise blood pressure  Oedema  Pulmonary oedema ALARMING SYMPTOMSMILD SYMPTOMS  Slight swelling over the ankles.  Swelling may extend to face, abdominal wall, vulva and even the whole body.  Headache  Diminished urine output.  Disturbed sleep.  Epigastric pain.  Eye symptoms  Blurring vision 3/28/20179
  • 12. COMPLICATIONS IMMEDIATE Maternal complication During pregnancy  Eclampsia  Accidental hemorrhage  Oliguria and anuria  Preterm labour  HELLP syndrome  Dimness of vision and even blindness  Cerebral hemorrhage  Acute respiratory distress syndrome (ARDS) 3/28/201712
  • 13. CONT….. During labour  Eclampsia  Postpartum hemorrhage Puerperium  Eclampsia  Shock  Sepsis. Fetal complications  Intrauterine death  Asphyxia  Prematurity  IUGR Remote complications  Residual hypertension  Recurrent pre-eclampsia  Chronic renal disease  Placental abruption 3/28/201713
  • 14. SCREENING TESTS  Doppler ultrasound  Presence of diastolic notch at 24 weeks gestation.  Absence of end diastolic frequencies.  Average mean arterial pressure (MAP) in second trimester more than 90 mm hg.  Fetal DNA. 3/28/201714
  • 15. PROPHYLACTIC MEASURES  Regular antenatal check-up.  Antithrombotic agents.  Heparin or low molecular weight.  Calcium supplementation (2 gms per day).  Antioxidants, vitamins E, C, and nutritional supplementation with magnesium, zinc, fish oil and low salt diet.  Balanced diet. 3/28/201715
  • 16. MANAGEMENT Objectives  To stabilize the hypertension and to prevent severe pre-eclampsia.  To prevent the complications.  To prevent eclampsia.  Delivery a healthy baby in optimal time.  Restoration of the health of the mother in Puerperium. 3/28/201716
  • 19. CONT….. DRUGS DOSE SCHEDULE MAXIMUM DOSE MAINTAINANCE DOSE Labetalol 10-20 mg, IV every 10 min 300 mg, IV 40 mg/hour Hydralazine 5 mg, IV every 30 min 30 mg, IV 10 mg/ hour Nifedipine 10-20 mg, orally, can be repeated in 30 min 240 mg/ 24 hour 4-6 hour interval Nitroglycerine 5 µg/ min IV Short term therapy only when the other drugs have failed.Sodium Nitroprusside 0.25-5 µg/kg/min IV Antihypertensive crisis The following drugs can be used when the BP is more than 160/110 mm hg or the MAP is more than 125 mm hg : 3/28/201719
  • 20. CONT….. MANAGEMENT DURATION OF TREATMENT GROUP- A METHODS OF DELIVERY INDUCTION OF LABOUR CAESAREAN SECTION GROUP- B GROUP- C 3/28/201720
  • 21. CONT….. Management during labour  Progress of labour recorded in partograph.  Abdominal and vaginal examination at regular intervals.  Bed rest in first stage of labour.  Cut short the second stage of labour with using prophylactic forceps.  Methergine contraindicated in 3rd stage. 3/28/201721
  • 22. SCHEME OF MANAGEMENT OF PRE- ECLAMPSIA 3/28/201722
  • 23. HEELLP SYNDROME  This is an acronym for haemolysis, elevated liver enzymes and low platelet count (< 100000 mm3).  This is rare complications in pre-eclampsia.  HELLP syndrome are developed even without maternal hypertension.  The symptoms are nausea, vomiting, Epigastric pain, right upper quadrant pain along with biochemical and hematological changes.  There may be sub capsular hematoma formation and peripheral blood smear. 3/28/201723
  • 24.  Antiseizure prophylaxis with magnesium sulphate (MgSO4) are started.  Anticorticosteroids administer to improves the perineal and maternal outcome.  Caesarean section are common mode of delivery.  Epidural anaesthesia can be used very safely if platelet count more than 100000 /mm3.  Platelet transfusion if count less than 50,000/mm3.  Recurrent risk of HELLP syndrome 3-19 %. 3/28/201724
  • 25. CONT….. Expectant management  This management carried out selectively :  When pregnancy less than 34 weeks.  With bed rest.  Plasma volume expansion.  Antithrombotic agent (Dipyridamole).  Anti-immunosuppressant (steroids).  Others (fresh frozen plasma). 3/28/201725
  • 26.  Abruptio placentae  Cerebral oedema  Pulmonary oedema  Laryngeal oedema  ARDS  Sepsis  Acute renal failure  Severe ascites  Retinal detachment  Subcapsular hematoma  Death 3/28/201726