Katherine A. Owen, PhD.
434-409-0821 ko4q@virginia.edu www.linkedin.com/pub/kate-owen/75/b3a/ba9/
Scientific Research Consultant
Research professional with over 10 years of technical experience across a broad range of scientific disciplines,
including cell biology, microbiology and immunology. Proven analytical and problem solving skills, including the
ability to take a research idea from conception, through scientific testing and on to high impact publication.
Areas of expertise include:
−Multidisciplinary collaboration −Excellent writing skills 	
 	
 	
 −Primary research techniques
−Project management −Public speaking, presentation skills −Data analysis
Professional Experience
Center for Open Science, Charlottesville, VA November 2014-Present
Scientific Consultant
Recruited to provide support for the Reproducibility Project: Cancer Biology to execute extensive literature
searches and consolidate data into written reports for publication. This is an on-going part-time collaboration
with Dr. Tim Errington.
University of Virginia, Charlottesville, VA
Research Instructor June 2013-Present
Research faculty position performing hypothesis-driven independent research investigating the pathogenesis
of disease, the innate immune response to bacterial infection, and the mechanisms of epithelial regeneration
and repair. Participating instructor in the biomedical sciences (BIMS) 6000 core course.
Key contributions:
§ On-going management of 3 scientific research projects resulting in 2 accepted publications and 1
submitted publication currently under review.
§ Management and mentoring of rotating graduate and undergraduate students; responsible for teaching
scientific techniques and providing guidance on data analysis and interpretation.
§ Generating successful collaborations, both within the UVA community and at other scientific institutions.
University of Virginia, Charlottesville, VA
Research Associate September 2007-June 2013
Recruited into the laboratory of Dr. James E. Casanova to conduct experimentation on Salmonella
pathogenesis using multiple in vivo animal models of infection. In addition to conducting independent research,
responsibilities included the development of laboratory protocols and extensive data analysis.
Key contributions:
§ Recipient of competitive Ruth L. Kirschstein National Research Service Award (NRSA).
§ Research published in high-impact peer reviewed scholarly journals including evaluation by the Faculty of
1000.
§ Invited speaker to present research at recent national conferences.
Genetics and IVF Institute, Fairfax, VA
Laboratory Technician December 1999-2001
Developed and implemented methodologies for the detection of genetic disorders. This included the novel use
of fluorescence in situ hybridization (FISH) to identify specific (abnormal) chromosomal regions in blastocytes,
and the maintenance of quality control standards in a dynamic clinical GLP-compliant laboratory
Katherine A. Owen, PhD.
434-409-0821 ko4q@virginia.edu www.linkedin.com/pub/kate-owen/75/b3a/ba9/
Education and Technical Proficiencies
University of Virginia, Charlottesville, VA
Doctor of Philosophy, Microbiology, Immunology and Cancer September 2007
§ Selected honors and awards: Dean’s fellowship awardee; first place for outstanding oral presentation at
annual Infectious Diseases and Biodefense Research Day; travel grant recipient for multiple regional and
national conferences
University of Birmingham, Edgbaston, United Kingdom	
  
Master of Science, Immunology and Infectious Diseases December 1999
§ Publication of thesis research: Jones et al., 2003, J. Antimicrob. Chemotherapy
Amherst College, Amherst, MA
Bachelor of Arts, Biology May 1997
Technical skills: Adobe Photoshop, Illustrator, Microsoft Office (Word, Excel, PowerPoint, Outlook), statistical
applications such as SPSS, R, MATLAB and Python.
Leadership and Service
§ Vice-President, Graduate Biosciences Society (GBS); Major duties involved the organization and planning
of the annual GBS Research Symposium.
§ UVA School of Medicine Graduate Student Orientation Committee; Organized student panel discussion
groups as part of first-year graduate student orientation.
§ UVA School of Medicine Institutional Self-Study Committee; Aided in the evaluation of graduate
education in basic sciences to prepare for LCME accreditation.
§ Robert J. Kadner Award for Outstanding Graduate Teaching Selection Committee
§ Student Talks Coordinator, Graduate Biosciences Society; Specific responsibilities included monthly
recruitment of student speakers and event planning.
Selected National Conference Presentations
§ 2015 Mid-Atlantic Microbial Pathogenesis Meeting, Wintergreen, VA. Invited speaker.
§ 2014 54th
American Society for Cell Biology (ASCB) Annual Meeting, Philadelphia, PA. Invited speaker.
§ 2011 FASEB meeting, Gastrointestinal Tract XIV: Stem cells, Adaptation, Inflammation and Cancer,
Steamboat Springs, CO. Invited speaker.
§ 2010 50th
American Society for Cell Biology (ASCB) Annual Meeting, Philadelphia, PA. Poster
Presentations.
§ 2009 FASEB meeting, Gastrointestinal Tract XIII: Advances in the Molecular and Cell Biology of the
Intestinal Epithelium: Development, Inflammation, Host Defense and Cancer, Snowmass Village, CO.
Poster Presentation.
§ 2007 47th
American Society for Cell Biology (ASCB) Annual Meeting, Washington D.C. Poster
Presentation.
§ 2006 The 9th
International Symposium on Yersinia, Lexington, KY. Poster Presentation.
Katherine A. Owen, PhD.
434-409-0821 ko4q@virginia.edu www.linkedin.com/pub/kate-owen/75/b3a/ba9/
Selected Publications
Owen, K.A., Anderson, C.J., Casanova, J.E. Salmonella suppresses the TRIF-dependent type I interferon
response in macrophages. Under review.
Das, S., Sarkar, A., Choudhury, S.S., Owen, K.A., Castillo, V., Fox, S., Eckmann, L, Michael R. Elliott,
M.R., Casanova, J.E., Ernst, P. ELMO1 has an essential role in the internalization of Salmonella
Typhimurium into enteric macrophages that impacts disease outcome. Cellular and Molecular
Gastroenterology and Hepatology. 2015. In press.
	
  
Owen, K.A., Meyer, C.B., Bouton, A.H., Casanova, J.E. Activation of focal adhesion kinase by Salmonella
suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in
macrophages. PLOS Pathogens 10 (6), e1004159, 2014.
Owen, K.A., Abshire, M.Y., Bouton, A.H., Casanova, J.E. FAK-dependent intestinal epithelial cell
proliferation is required for efficient mucosal wound healing. Plos ONE 6 (8), e23123, 2011. This
publication was recently reviewed by the Faculty of 1000.
Abshire, M.A., Thomas, K.S., Owen, K.A., Bouton, A.H. Macrophage motility requires distinct α5β1/FAK
and α4β1/paxillin signaling events. The Journal of Leukocyte Biology, 89 (2), 251-257, 2011.
Das, S., Owen, K.A., Ly, K., Park, D., Black, S.G., Wilson, J.M., Sifri, C., Ravichandran, K.S., Ernst, P.B.,
Casanova, J.E. Recognition of Gram-negative bacteria by a novel pattern recognition receptor BAI1 (Brain
Angiogenesis Factor 1). PNAS, 108 (5), 2136-2141, 2011.
Owen, K.A., Pixley, F.J., Thomas, K.S, Vicente-Manazanares, M., Ray, B.J., Horwitz, A.F., Parsons, J.T.,
Beggs, H.E., Stanley, E.R., Bouton, A.H. FAK regulates lamellipodial persistence, adhesion turnover and
motility in macrophages. The Journal of Cell Biology, 179 (6), 1275-1287, 2007.
Owen, K.A., Thomas, K.S., Bouton, A.H. The differential expression of Yersinia pseudotuberculosis
adhesins determines the requirement for FAK and/or Pyk2 during bacterial phagocytosis by macrophages.
Cellular Microbiology, 9 (3), 596-609, 2007.

PRA resume

  • 1.
    Katherine A. Owen,PhD. 434-409-0821 ko4q@virginia.edu www.linkedin.com/pub/kate-owen/75/b3a/ba9/ Scientific Research Consultant Research professional with over 10 years of technical experience across a broad range of scientific disciplines, including cell biology, microbiology and immunology. Proven analytical and problem solving skills, including the ability to take a research idea from conception, through scientific testing and on to high impact publication. Areas of expertise include: −Multidisciplinary collaboration −Excellent writing skills −Primary research techniques −Project management −Public speaking, presentation skills −Data analysis Professional Experience Center for Open Science, Charlottesville, VA November 2014-Present Scientific Consultant Recruited to provide support for the Reproducibility Project: Cancer Biology to execute extensive literature searches and consolidate data into written reports for publication. This is an on-going part-time collaboration with Dr. Tim Errington. University of Virginia, Charlottesville, VA Research Instructor June 2013-Present Research faculty position performing hypothesis-driven independent research investigating the pathogenesis of disease, the innate immune response to bacterial infection, and the mechanisms of epithelial regeneration and repair. Participating instructor in the biomedical sciences (BIMS) 6000 core course. Key contributions: § On-going management of 3 scientific research projects resulting in 2 accepted publications and 1 submitted publication currently under review. § Management and mentoring of rotating graduate and undergraduate students; responsible for teaching scientific techniques and providing guidance on data analysis and interpretation. § Generating successful collaborations, both within the UVA community and at other scientific institutions. University of Virginia, Charlottesville, VA Research Associate September 2007-June 2013 Recruited into the laboratory of Dr. James E. Casanova to conduct experimentation on Salmonella pathogenesis using multiple in vivo animal models of infection. In addition to conducting independent research, responsibilities included the development of laboratory protocols and extensive data analysis. Key contributions: § Recipient of competitive Ruth L. Kirschstein National Research Service Award (NRSA). § Research published in high-impact peer reviewed scholarly journals including evaluation by the Faculty of 1000. § Invited speaker to present research at recent national conferences. Genetics and IVF Institute, Fairfax, VA Laboratory Technician December 1999-2001 Developed and implemented methodologies for the detection of genetic disorders. This included the novel use of fluorescence in situ hybridization (FISH) to identify specific (abnormal) chromosomal regions in blastocytes, and the maintenance of quality control standards in a dynamic clinical GLP-compliant laboratory
  • 2.
    Katherine A. Owen,PhD. 434-409-0821 ko4q@virginia.edu www.linkedin.com/pub/kate-owen/75/b3a/ba9/ Education and Technical Proficiencies University of Virginia, Charlottesville, VA Doctor of Philosophy, Microbiology, Immunology and Cancer September 2007 § Selected honors and awards: Dean’s fellowship awardee; first place for outstanding oral presentation at annual Infectious Diseases and Biodefense Research Day; travel grant recipient for multiple regional and national conferences University of Birmingham, Edgbaston, United Kingdom   Master of Science, Immunology and Infectious Diseases December 1999 § Publication of thesis research: Jones et al., 2003, J. Antimicrob. Chemotherapy Amherst College, Amherst, MA Bachelor of Arts, Biology May 1997 Technical skills: Adobe Photoshop, Illustrator, Microsoft Office (Word, Excel, PowerPoint, Outlook), statistical applications such as SPSS, R, MATLAB and Python. Leadership and Service § Vice-President, Graduate Biosciences Society (GBS); Major duties involved the organization and planning of the annual GBS Research Symposium. § UVA School of Medicine Graduate Student Orientation Committee; Organized student panel discussion groups as part of first-year graduate student orientation. § UVA School of Medicine Institutional Self-Study Committee; Aided in the evaluation of graduate education in basic sciences to prepare for LCME accreditation. § Robert J. Kadner Award for Outstanding Graduate Teaching Selection Committee § Student Talks Coordinator, Graduate Biosciences Society; Specific responsibilities included monthly recruitment of student speakers and event planning. Selected National Conference Presentations § 2015 Mid-Atlantic Microbial Pathogenesis Meeting, Wintergreen, VA. Invited speaker. § 2014 54th American Society for Cell Biology (ASCB) Annual Meeting, Philadelphia, PA. Invited speaker. § 2011 FASEB meeting, Gastrointestinal Tract XIV: Stem cells, Adaptation, Inflammation and Cancer, Steamboat Springs, CO. Invited speaker. § 2010 50th American Society for Cell Biology (ASCB) Annual Meeting, Philadelphia, PA. Poster Presentations. § 2009 FASEB meeting, Gastrointestinal Tract XIII: Advances in the Molecular and Cell Biology of the Intestinal Epithelium: Development, Inflammation, Host Defense and Cancer, Snowmass Village, CO. Poster Presentation. § 2007 47th American Society for Cell Biology (ASCB) Annual Meeting, Washington D.C. Poster Presentation. § 2006 The 9th International Symposium on Yersinia, Lexington, KY. Poster Presentation.
  • 3.
    Katherine A. Owen,PhD. 434-409-0821 ko4q@virginia.edu www.linkedin.com/pub/kate-owen/75/b3a/ba9/ Selected Publications Owen, K.A., Anderson, C.J., Casanova, J.E. Salmonella suppresses the TRIF-dependent type I interferon response in macrophages. Under review. Das, S., Sarkar, A., Choudhury, S.S., Owen, K.A., Castillo, V., Fox, S., Eckmann, L, Michael R. Elliott, M.R., Casanova, J.E., Ernst, P. ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. Cellular and Molecular Gastroenterology and Hepatology. 2015. In press.   Owen, K.A., Meyer, C.B., Bouton, A.H., Casanova, J.E. Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages. PLOS Pathogens 10 (6), e1004159, 2014. Owen, K.A., Abshire, M.Y., Bouton, A.H., Casanova, J.E. FAK-dependent intestinal epithelial cell proliferation is required for efficient mucosal wound healing. Plos ONE 6 (8), e23123, 2011. This publication was recently reviewed by the Faculty of 1000. Abshire, M.A., Thomas, K.S., Owen, K.A., Bouton, A.H. Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events. The Journal of Leukocyte Biology, 89 (2), 251-257, 2011. Das, S., Owen, K.A., Ly, K., Park, D., Black, S.G., Wilson, J.M., Sifri, C., Ravichandran, K.S., Ernst, P.B., Casanova, J.E. Recognition of Gram-negative bacteria by a novel pattern recognition receptor BAI1 (Brain Angiogenesis Factor 1). PNAS, 108 (5), 2136-2141, 2011. Owen, K.A., Pixley, F.J., Thomas, K.S, Vicente-Manazanares, M., Ray, B.J., Horwitz, A.F., Parsons, J.T., Beggs, H.E., Stanley, E.R., Bouton, A.H. FAK regulates lamellipodial persistence, adhesion turnover and motility in macrophages. The Journal of Cell Biology, 179 (6), 1275-1287, 2007. Owen, K.A., Thomas, K.S., Bouton, A.H. The differential expression of Yersinia pseudotuberculosis adhesins determines the requirement for FAK and/or Pyk2 during bacterial phagocytosis by macrophages. Cellular Microbiology, 9 (3), 596-609, 2007.