Yihua Cai is a male graduate student from China studying molecular biochemistry and bioinformatics at George Washington University. He received his bachelor's degree from China Pharmaceutical University. His research focuses on identifying inhibitors that can overcome platinum resistance in ovarian cancer, including projects on JAK2 and HIF-1α inhibitors. He has work experience in cancer research laboratories and the pharmaceutical industry in China. He has published papers and presented his research findings at his university.

1. Curriculum Vitae
Name: Yihua Cai
Gender:Male
Date and place of birth: 09/26/1990, China
Home address: 500 23rd
ST, NW, APT B806, Washington DC, U.S.
Telephone:202-714-2233 (Cell)
Email address: yhcai@gwu.edu
Education
2014/01-2016/08 M.S., Molecular Biochemistry and Bioinformatics,
George Washington University, DC, U.S.
2009/09-2013/07 B.S., The national base of life science and biotechnology education,
China Pharmaceutical University, Jiangsu, China
Employment
2014/05-present Research Assistant, Cancer Center, George Washington University
2013/03-2013/05 Intern, Medicinal Chemistry Office, Zhangzhou Institute for Drug Control
2012/05-2012/08 Intern, In Vitro Pharmacology Office, Simcere Pharmaceutical Group
Research Project
1. Identify JAK2 inhibitor overcoming platinum resistance in ovarian cancer using high-
throughput screening.
2. HIF-1α inhibitors overcoming platinum resistance in ovarian cancer.
3. Identify whether WDHD1 could be an oncogene for oncology target therapy through mice
xenograft model.
4. Telomerase specific oncolytic adenovirus expressing TRAIL suppresses peritoneal
dissemination of gastric cancer.
Professional Skills
Biochemistry: Mammalian cell culture, Western blot, Drug screening, Flow-Cytometry, ELISA.

2. Molecular Biology: DNA and RNA extraction, Gel electrophoresis, PCR, RT-PCR, Real-time
PCR, Primer design, siRNA/shRNA transfection, Plasmid construction, Plasmid transfection.
Bioinformatics: Primer Premier, Python in Linux environment, Alignment, BLAST, Database
filtering and sorting.
Software: Microsoft Office, Graphpad Prism, SQL, R.
Animal: Xenograft model establish, IP, SC injection and oral gavage, Tissue & Blood
collection, Primary cell culture, H & E staining, Immunohistochemistry, TUNEL essay.
Societies and Honors
2009 Fist class scholarship in China Pharmaceutical University
2010 Second class scholarship in China Pharmaceutical University
Educational Achievements
Laboratory teaching
Undergraduate students: Jennifer B Lee (GWU 2015-2016)
Publications
Zhou W, Dai S, Zhu H, Song Z, Cai Y, Lee J, Hu X, Fang B, He C, Huang X. Telomerase
specific oncolytic adenovirus expressing TRAIL suppresses peritoneal dissemination of
gastric cancer. Gene Ther. Under revision, 2016.
Zhou W*, Cai Y*(co-first author), Sun W, Hao Q, Li Z, Zheng W, Zhu W (2016). Using high-
throughput screening to identify HIF-1 inhibitor sensitizes chemo resistant ovarian cancer. In
Submission
Zhou W*, Cai Y*(co-first author), Dai S, Sun W, Hao Q, Li Z, Hao J, Su S, Zheng W, Zhu W
(2016). Identify JAK2 inhibitor overcoming platinum resistance in ovarian cancer through
high-throughput screening. In Submission
Presentations
Regional presentations (Oral presentations)
11/2016 “Autocrine of cytokines mediates platinum resistance in ovarian cancer”, GWU
09/2016 “HIF-1α inhibitors overcoming platinum resistance in ovarian cancer”, GWU
05/2016 “Identify JAK2 inhibitors overcoming platinum resistance in ovarian cancer”, GWU