Radiation shielding is needed for megavoltage photon therapy machines to limit radiation exposure and reduce effective dose outside of treatment rooms. Approximately 50% of cancer patients receive radiation therapy. Shielding barriers like lead and concrete are used to reduce radiation levels in uncontrolled and controlled areas like corridors and waiting rooms based on factors like workload, use, and occupancy. Proper machine orientation and maze or direct door designs can further reduce dose near room entrances. Ducting and electrical routing must also consider radiation protection. Skyshine radiation from scattered photons above the treatment room requires special consideration in shielding design.