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Case history
Name: xxx
Age : 75 years
Sex : Male
Chief Complaints
LE: c/o of gradual decrease in vision for both distance and near
x 3 years
No other specific ocular complaints
Previous Ocular History
BE: h/o cataract Sx done in RE 10 years ago and in LE 3 years
ago.
H/o of wearing spectacles x 15 years.
No h/o of trauma
BE- both eye, RE- right eye, LE- left eye, Sx- surgery
4/18/2018 2
Family history
Not contributory
General health:
H/o DM x 10 years,
H/o HTN x 5 years,
H/o renal problem x 10 years
Recent investigation
Nil
Current medication
T. Amlong o.d, T. Sartel 40 mg o.d, T. Pankareoflat o.d,
T. Shelcal 500 mg o.d, T. Nephrocaps o.d, T. Renerve plus o.d
Allergies
Not aware of
4/18/2018 3
DM-diabetes mellitus, HTN- hypertension
Previous glass precription x 3 years
Not brought
Visual acuity
Distance vision with Snellen chart at 6m
(Without Rx) RE: 6/9 NIP
LE: 1/60 NIP
Near vision with continuous text chart at 40 cm
(Without Rx) RE: N10
LE: N36
4/18/2018 4
NIP- no improvement with pinhole
Objective refraction
RE: -1.00 DS/-1.00 DC x 120 (clear reflex)
LE: +0.00 (very dull reflex)
Acceptance
RE: plano (6/9 NI)
LE: plano (1/60 NI)
Add
RE: +3.00 DS (N6)
LE: +3.00 DS (N36)
4/18/2018 5
@ 40cm
Pupils
RE: irregular, RTL, No RAPD
LE: irregular, RTL, RAPD II
Extra-Ocular Motility test
RE: SAFE
LE: SAFE
Cover test
Distance : ortho
Near : ortho
4/18/2018 6
SAFE- Smooth, accurate and fully extensive
Slit lamp examination
Upper lids
normal
Conjunctiva
pallor
Cornea clear
RTL
PXF
ACD III
RE
LE
Lower lids normal
PCO I PCO IIIPCIOL in situ
4/18/2018 7
IOP with Goldman applanation tonometer @5:00 PM
RE: 16 mmHg
LE: 16 mmHg
4/18/2018 8
Fundus Examination
4/18/2018 9
Disc vessesl
normal
CDR 0.4
Pallor disc
FR+
Dull FR
RE LE
Media clear Media hazy
Diagnosis
BE: Posterior Capsular Opacification
BE: Pseudophakia
RE: Pseudoexfoliation
LE: RAPD II
Advice
OS: Advised to go for YAG- Capsulotomy
Treatment
OS: YAG- Capsulotomy done(9-12-17)
4/18/2018 10
Follow up after 1 week
Visual Acuity
Distance vision with Snellen Chart @6m
(With Rx) RE: 6/9 NIP
LE: 6/18 NIP
Near vision with continuous text chart @ 40 cm
(With Rx) RE: N6
LE: N6 with strain
Previous glass precription (Kryptok bifocals)x 3 years
RE: -0.75 DS
LE: -1.00 DS
4/18/2018 11
ADD: BE: +3-00 DS
Objective refraction
RE: -1.00 DS/-1.00 DC x 120(clear reflex)
LE: -1.00 DS/-1.00 DC x 90(clear reflex)
Acceptance
RE: -0.75 DS (6/9) NI
LE: -1.00 DS (6/18) NI
Add
RE: +3.00 DS (N6)
LE: +3.00 DS (N6 with strain)
4/18/2018 12
Prefers same RX
@ 40 cm
Pupils
RE: irregular, RTL, No RAPD
LE: irregular, RTL, RAPD II
Extra-ocular Motility test
RE: SAFE
LE: SAFE
Cover test
Distance : ortho
Near : ortho
4/18/2018 13
SAFE-Smooth, accurate and fully extensive
Slit lamp examination
Upper lids
normal
Conjunctiva
pallor
Cornea clear
RTL
PXF
ACD III
RE
LE
Lower lids normal
PCO I
4/18/2018 14
PCIOL insitu
IOP with Goldman applanation tonometer @5:00 PM
RE: 12 mmHg
LE: 12 mmHg
4/18/2018 15
Fundus examination
Not done
Advice
Continue to wear same Rx
Review SOS
4/18/2018 16
Reasons for NI in LE visual acuity might be the reasons of retinal diseases or
amblyopia plus RAPDII and the pallor disc suggests having optic nerve
lesions, neuropatyhy or neuritis ..
Posterior Capsular Opacification (PCO)
• After or secondary cataract
• Multifactorial physiological
causes
Incidence
• Occurs upto 50% of after complicated Cataract Sx 1,2
• Higher rate in children upto 100%1,2,
4/18/2018 17
PCO
Fibrosis type Pearl type
1.Proliferation 2.Migration of cells 3. Differentiation of cells
1.Complicated
Cataract surgery
2.IOL material and
designs
3. Size and
position of CCC
4/18/2018 18
Pathogenesis of PCO
Residual LECs
CCC- continuous curvilinear capsulorehexis
4/18/2018 19
4/18/2018 20
Symptoms
• Gradual decrease in vision
• Glare
• Monocular diplopia
Signs
• Decreased visual acuity if the PCO blocks the visual axis
• Soemmering ring1
• Elschnigs pearl
• Fibrosis PCO
4/18/2018 21Capsular fibrosis
4/18/2018 22
Gradings of PCO3,5
Grades Severity PCO
0 None No PCO
1 Slight PCO not reaching the edge of optic
2 Moderate PCO reaching the edge
3 Pronounced PCO beyond the edge but visual axis is clear
4 Severe PCO on the visual axis
4/18/2018 23
4/18/2018 24
EPCO Gradings of PCO2
Grade Severity PCO
o None Clear lens
1 Minimal Mild caspsule wrinkling, homogenous lay
er of LECs
2 Mild Honeycomb pattern, denser layer of LECs
3 Moderate Elschnigs pearl, thick layer of LECs
4 Severe Very Thick elschnig pearl with darkening
effect and severe PCO
4/18/2018 25
EPCO-Evaluation of posterior capsular opacification
Treatment
• In pediatrics, anterior vitrectomy with membranectomy.
• In children, anterior vitrectomy and posterior capsulotomy
• In adults, Nd YAG: Posterior Capsulotomy
4/18/2018 26
Nd YAG: Capsulotomy
Opening of capsule with laser
4/18/2018 27
1. Cruciate opening 2. Circular opening
4/18/2018 28
Complications of YAG- Capsulotomy1,2,3,4,5
• Corneal oedema
• IOL damage or subluxation
• Elevation of IOP
• Vitreous floaters
• Cystoid Macular Edema
• Retinal Detachment
4/18/2018 29
Reference
1. Brad Bowling, Kanski’s Clinical ophthalmology- a systemic approach, 8th Edition
2. Wejde, G. (2005). Posterior capsule opacification and postoperative endophthalmitis
following cataract surgery: Predictive and protective factors. Institutionen för klinisk
neurovetenskap/Department of Clinical Neuroscience.
3. Wahab, S., Ahmed, J., & Hasan, K. S. (2011). Pars plana surgical capsulotomy for po
sterior capsular opacification (PCO). JPMA-Journal of the Pakistan Medical Associat
ion, 61(1), 14.
4. Elkin, Z. P., Piluek, W. J., & Fredrick, D. R. (2016). Revisiting secondary capsulotom
y for posterior capsule management in pediatric cataract surgery. Journal of America
n Association for Pediatric Ophthalmology and Strabismus {JAAPOS}, 20(6), 506-5
10.
5. Na, Y. H., Shin, J. Y., Lee, J. H., Kim, J. H., & Lee, D. H. (2016). Incidence of Poster
ior Capsular Opacification Based on Low and High Fluid-dynamic Parameters. Journ
al of the Korean Ophthalmological Society, 57(10), 1555-1562.
6. Hashemi, H., Mohammadi, S. F., Majdi, M., Fotouhi, A., & Khabazkhoob, M. (2012)
. Posterior capsule opacification after cataract surgery and its determinants. Iran J Op
hthalmol, 24, 3-8.
4/18/2018 30

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Posterior capsular opacification

  • 1.
  • 2. Case history Name: xxx Age : 75 years Sex : Male Chief Complaints LE: c/o of gradual decrease in vision for both distance and near x 3 years No other specific ocular complaints Previous Ocular History BE: h/o cataract Sx done in RE 10 years ago and in LE 3 years ago. H/o of wearing spectacles x 15 years. No h/o of trauma BE- both eye, RE- right eye, LE- left eye, Sx- surgery 4/18/2018 2
  • 3. Family history Not contributory General health: H/o DM x 10 years, H/o HTN x 5 years, H/o renal problem x 10 years Recent investigation Nil Current medication T. Amlong o.d, T. Sartel 40 mg o.d, T. Pankareoflat o.d, T. Shelcal 500 mg o.d, T. Nephrocaps o.d, T. Renerve plus o.d Allergies Not aware of 4/18/2018 3 DM-diabetes mellitus, HTN- hypertension
  • 4. Previous glass precription x 3 years Not brought Visual acuity Distance vision with Snellen chart at 6m (Without Rx) RE: 6/9 NIP LE: 1/60 NIP Near vision with continuous text chart at 40 cm (Without Rx) RE: N10 LE: N36 4/18/2018 4 NIP- no improvement with pinhole
  • 5. Objective refraction RE: -1.00 DS/-1.00 DC x 120 (clear reflex) LE: +0.00 (very dull reflex) Acceptance RE: plano (6/9 NI) LE: plano (1/60 NI) Add RE: +3.00 DS (N6) LE: +3.00 DS (N36) 4/18/2018 5 @ 40cm
  • 6. Pupils RE: irregular, RTL, No RAPD LE: irregular, RTL, RAPD II Extra-Ocular Motility test RE: SAFE LE: SAFE Cover test Distance : ortho Near : ortho 4/18/2018 6 SAFE- Smooth, accurate and fully extensive
  • 7. Slit lamp examination Upper lids normal Conjunctiva pallor Cornea clear RTL PXF ACD III RE LE Lower lids normal PCO I PCO IIIPCIOL in situ 4/18/2018 7
  • 8. IOP with Goldman applanation tonometer @5:00 PM RE: 16 mmHg LE: 16 mmHg 4/18/2018 8
  • 9. Fundus Examination 4/18/2018 9 Disc vessesl normal CDR 0.4 Pallor disc FR+ Dull FR RE LE Media clear Media hazy
  • 10. Diagnosis BE: Posterior Capsular Opacification BE: Pseudophakia RE: Pseudoexfoliation LE: RAPD II Advice OS: Advised to go for YAG- Capsulotomy Treatment OS: YAG- Capsulotomy done(9-12-17) 4/18/2018 10
  • 11. Follow up after 1 week Visual Acuity Distance vision with Snellen Chart @6m (With Rx) RE: 6/9 NIP LE: 6/18 NIP Near vision with continuous text chart @ 40 cm (With Rx) RE: N6 LE: N6 with strain Previous glass precription (Kryptok bifocals)x 3 years RE: -0.75 DS LE: -1.00 DS 4/18/2018 11 ADD: BE: +3-00 DS
  • 12. Objective refraction RE: -1.00 DS/-1.00 DC x 120(clear reflex) LE: -1.00 DS/-1.00 DC x 90(clear reflex) Acceptance RE: -0.75 DS (6/9) NI LE: -1.00 DS (6/18) NI Add RE: +3.00 DS (N6) LE: +3.00 DS (N6 with strain) 4/18/2018 12 Prefers same RX @ 40 cm
  • 13. Pupils RE: irregular, RTL, No RAPD LE: irregular, RTL, RAPD II Extra-ocular Motility test RE: SAFE LE: SAFE Cover test Distance : ortho Near : ortho 4/18/2018 13 SAFE-Smooth, accurate and fully extensive
  • 14. Slit lamp examination Upper lids normal Conjunctiva pallor Cornea clear RTL PXF ACD III RE LE Lower lids normal PCO I 4/18/2018 14 PCIOL insitu
  • 15. IOP with Goldman applanation tonometer @5:00 PM RE: 12 mmHg LE: 12 mmHg 4/18/2018 15
  • 16. Fundus examination Not done Advice Continue to wear same Rx Review SOS 4/18/2018 16 Reasons for NI in LE visual acuity might be the reasons of retinal diseases or amblyopia plus RAPDII and the pallor disc suggests having optic nerve lesions, neuropatyhy or neuritis ..
  • 17. Posterior Capsular Opacification (PCO) • After or secondary cataract • Multifactorial physiological causes Incidence • Occurs upto 50% of after complicated Cataract Sx 1,2 • Higher rate in children upto 100%1,2, 4/18/2018 17
  • 18. PCO Fibrosis type Pearl type 1.Proliferation 2.Migration of cells 3. Differentiation of cells 1.Complicated Cataract surgery 2.IOL material and designs 3. Size and position of CCC 4/18/2018 18 Pathogenesis of PCO Residual LECs CCC- continuous curvilinear capsulorehexis
  • 21. Symptoms • Gradual decrease in vision • Glare • Monocular diplopia Signs • Decreased visual acuity if the PCO blocks the visual axis • Soemmering ring1 • Elschnigs pearl • Fibrosis PCO 4/18/2018 21Capsular fibrosis
  • 23. Gradings of PCO3,5 Grades Severity PCO 0 None No PCO 1 Slight PCO not reaching the edge of optic 2 Moderate PCO reaching the edge 3 Pronounced PCO beyond the edge but visual axis is clear 4 Severe PCO on the visual axis 4/18/2018 23
  • 25. EPCO Gradings of PCO2 Grade Severity PCO o None Clear lens 1 Minimal Mild caspsule wrinkling, homogenous lay er of LECs 2 Mild Honeycomb pattern, denser layer of LECs 3 Moderate Elschnigs pearl, thick layer of LECs 4 Severe Very Thick elschnig pearl with darkening effect and severe PCO 4/18/2018 25 EPCO-Evaluation of posterior capsular opacification
  • 26. Treatment • In pediatrics, anterior vitrectomy with membranectomy. • In children, anterior vitrectomy and posterior capsulotomy • In adults, Nd YAG: Posterior Capsulotomy 4/18/2018 26
  • 27. Nd YAG: Capsulotomy Opening of capsule with laser 4/18/2018 27 1. Cruciate opening 2. Circular opening
  • 29. Complications of YAG- Capsulotomy1,2,3,4,5 • Corneal oedema • IOL damage or subluxation • Elevation of IOP • Vitreous floaters • Cystoid Macular Edema • Retinal Detachment 4/18/2018 29
  • 30. Reference 1. Brad Bowling, Kanski’s Clinical ophthalmology- a systemic approach, 8th Edition 2. Wejde, G. (2005). Posterior capsule opacification and postoperative endophthalmitis following cataract surgery: Predictive and protective factors. Institutionen för klinisk neurovetenskap/Department of Clinical Neuroscience. 3. Wahab, S., Ahmed, J., & Hasan, K. S. (2011). Pars plana surgical capsulotomy for po sterior capsular opacification (PCO). JPMA-Journal of the Pakistan Medical Associat ion, 61(1), 14. 4. Elkin, Z. P., Piluek, W. J., & Fredrick, D. R. (2016). Revisiting secondary capsulotom y for posterior capsule management in pediatric cataract surgery. Journal of America n Association for Pediatric Ophthalmology and Strabismus {JAAPOS}, 20(6), 506-5 10. 5. Na, Y. H., Shin, J. Y., Lee, J. H., Kim, J. H., & Lee, D. H. (2016). Incidence of Poster ior Capsular Opacification Based on Low and High Fluid-dynamic Parameters. Journ al of the Korean Ophthalmological Society, 57(10), 1555-1562. 6. Hashemi, H., Mohammadi, S. F., Majdi, M., Fotouhi, A., & Khabazkhoob, M. (2012) . Posterior capsule opacification after cataract surgery and its determinants. Iran J Op hthalmol, 24, 3-8. 4/18/2018 30

Editor's Notes

  1. Pseudoexfoliation syndrome (PES)is associated with atrophy of the iris and pupillary ruff with insufficient mydriasis, weak zonulae and risk of capsule ⁄ zonulae rupture with vitreous loss during cataract surgery
  2. Pupils were oval shape
  3. Pallor conjunctiva- sign of anaemia- mostly the palpebral conjunctiva seems pale which is supposed to be red – due to degradation of billirubin Pallor sclera- sign of jaundice
  4. CCC –centred, less than 0-5 -1mm less than iol Fibrosis Pco –occurs due to metaplaisa of fibres To small – more iris capture To big- capsle phimosis(contraction or shrinkage occurs) which leads to fibrosis proliferation ideal IOL -6mm CCC-5-5
  5. Fibrosis PCO—undergoes metaplasia- giving spindle like structure
  6. Pearl_- proliferated swollen epithelial cells giving round shape in clusters Soemmering ring- ring like proliferation of LECs around the periphery
  7. Cruciate- crossed shape Tx- anti inflammatory drugs and IOP decreasing drugs
  8. Scheimflug slit images and retroillumiation