This document outlines guidelines for post-catheterization follow up to monitor patients for changes in their condition and prepare them for discharge. Key aspects of monitoring include checking haemodynamics, symptoms of ischemia or heart failure, arrhythmias, and contrast-induced nephropathy. Potential complications are discussed like bleeding, access site issues, and allergic reactions. The document also covers instructing patients on activity levels, follow up care including medication and lifestyle changes, and timing of return to work.
Management of Heart Failure in the ED Setting:
An Evidence-Based Review of the Literature
J Emerg Med, 2018 Sep 26.
doi: 10.1016/j.jemermed.2018.08.002
2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes: Executive Summary
Circulation. published online September 23, 2014
Anaesthesia in Cardiac Patients for Non-cardiac SurgeryRashad Siddiqi
The reader should be able to:
(1) identify factors which will lead to increased cardiovascular risk for patients undergoing non-cardiac surgery
(2) decide which patients require further cardiovascular testing
(3) make optimization plan for such patients
(4) understand the principles of anaesthesia for patients with cardiac disease
PCI is one of the most common procedures in the US, and remain a cornerstone in the management of ischemic heart disease.
Historically, a large proportion of PCI procedures were performed during inpatient hospitalization, allowing for a significant amount of time for monitoring postprocedure to ensure procedural success & identify bleeding or vascular complications, as well as for initiating secondary prevention.
However, technological pharmacological and procedural innovations, as well as payer expectations and cost considerations, have led to a shorter length of stay postprocedure and obviate hospital admission.
Most non-acute MI PCIs performed in the US now are performed under an outpatient designation.
Management of Heart Failure in the ED Setting:
An Evidence-Based Review of the Literature
J Emerg Med, 2018 Sep 26.
doi: 10.1016/j.jemermed.2018.08.002
2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes: Executive Summary
Circulation. published online September 23, 2014
Anaesthesia in Cardiac Patients for Non-cardiac SurgeryRashad Siddiqi
The reader should be able to:
(1) identify factors which will lead to increased cardiovascular risk for patients undergoing non-cardiac surgery
(2) decide which patients require further cardiovascular testing
(3) make optimization plan for such patients
(4) understand the principles of anaesthesia for patients with cardiac disease
PCI is one of the most common procedures in the US, and remain a cornerstone in the management of ischemic heart disease.
Historically, a large proportion of PCI procedures were performed during inpatient hospitalization, allowing for a significant amount of time for monitoring postprocedure to ensure procedural success & identify bleeding or vascular complications, as well as for initiating secondary prevention.
However, technological pharmacological and procedural innovations, as well as payer expectations and cost considerations, have led to a shorter length of stay postprocedure and obviate hospital admission.
Most non-acute MI PCIs performed in the US now are performed under an outpatient designation.
To provide quick, painless & safe recovery from surgery as soon as possible.
Learning Objectives:
1.The need for immediate post-op care
2. Common post-operative problems
3. Anticipation & prevention of common complications
4. Identification & Treatment
5. Enhancement of recovery
6. Systematic discharge
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
1. Post Catheterization Follow Up
Chairperson: Prof Dr. Syed Ali Ahsan
Dr. Md. Fysal Faruq
Resident Phase B
Yellow unit
2. Aims of Follow up
• Monitoring for changes in haemodynamics
• Monitoring for new symptoms
• Monitoring for contrast induced nephropathy
• Prepare the patient for ambulation
• Prepare the patient for discharge
3. Change of haemodynamics
• Possible causes:
• Blood loss
• Myocardial ischaemia
• Heart failure
• Arrhythmia
• Hypovolemia due to inadequate pre-hydration
4. Haemodynamics monitoring in CCU
• After PCI patient should be monitored in a
cardiac ward that has facility of continuous
ECG monitoring and nurses expertized with
routine post-PCI care.
• Check vital signs every 15 minutes for the first
2 hours then every hourly
• Pulse, BP, Urine output, Precordium, Lungs,
peripheral pulses, puncture site
5. Monitoring for myocardial ischaemia
• A 12-lead ECG should be obtained just after
PCI to find out any new changes
• Measurement of Troponin I or CK(MB)
-Symptoms of ischaemia
-New ECG changes
6. Monitoring for contrast-induced
nephropathy
• Ensure first voiding of urine
• Encourage oral fluid intake
• Nephrotoxic drugs should be withheld 24
hours before and 48 hours after procedure
• Post-procedure oral or saline hydration should
be continued to maintain urine output >
30ml/hour
• Renal function should be monitored in
patients with DM and renal dysfunction.
7. Monitoring for Heart failure
• Correlate with symptoms and signs: SOB,
Palpitation, tachycardia, bilateral basal creps
• Arrangement for immediate bed-side
echocardiography should be available
- New wall motion abnormalities
- Development of Pericardial effusion or
temponade
8. Monitoring for Arrhythmias
• Any type of arrhythmias are possible
• Common: sinus tachycardia, sinus bradycardia,
• Life threatening: AF, VT, VF
• Arrangement for pharmacological and DC
cardioversion Should be available
10. Timing of sheath removal(SCAI)
• Trans-femoral access
Heparin used as anticoagulant
ACT falls below 175 seconds
Bivalirudin used as anticoagulant
o Creatinine Clearance >30ml/hour
2 hours after discontinuation of bivalirudin
o CCR <30ml/hour or haemodialysis
ACT falls below 175 seconds
12. Ambulation
• Trans-femoral access
Manual compression: 2-6 hours
Vascular closure device: 1-4 hours
• Trans-radial access
May ambulate as soon as sheath removal
Avoid weight bearing or other activity for 2-4
hours
13. Physician patient communication
• The results of the procedure, including any
complications, unexpected findings, should be
explained clearly to the patient and his or her
family.
• The type of intervention, if any, and the
duration of dual antiplatelet therapy (DAPT)
should also be discussed and reinforced
repeatedly by the team of care providers
throughout the duration of the patient stay.
14. Instructions after sheath removal
• Keep the punctured limb straight and do not
flex knee for 6 hours
• During coughing or sneezing, apply pressure
to puncture site
• Should not strain or lift anything >5pound
(2.25kg) within 48hours
• Call the duty nurse or doctor if oozing from
puncture site, painful swelling, neurological
symptoms like tingling, numbness, parasthesia
15. Blood loss
• Possible causes:
• Haematoma
• Retroperitoneal haemorrhage
• Puncture site bleeding
16. Haematoma
• Collection of blood under the skin in soft
tissues directly as a result of arterial/venous
injury
• Pain
• Firm swelling around access site
• Red or purple skin discoloration
• Tachycardia, hypotension
17. • Treatment:
• Manual compression to prevent further
enlargement of hematoma
• Mark the boundaries of the hematoma to
monitor growth and effectiveness of
compression
• Blood grouping, crossmatching, Blood
transfusion if needed
• Vascular surgery consultation
19. • Treatment:
• Can be treated by supportive care
(transfusions, close observation, and bed rest)
in > 80% of cases
• Anticoagulation should be reversed
• Frequent hemodynamic monitoring in an
experienced intensive care unit
• If the bleeding does not spontaneously stop,
then vascular surgery consultation
21. Pseudoaneurysms
• Dilation of an artery with actual disruption of one
or more layers of its wall
• Pulsatile mass over puncture site
• Auscultation: Systolic bruit
• Confirmation: Ultrasound
• Treatment:
• Less than 2 cm: Often close spontaneously
• 2-3 cm: USG guided compression(90%success)
• More than 3 cm: Surgical correction
22. Arteriovenous fistula
• Formation of a direct communication between
an artery and a vein
• Auscultation: Continuous murmur
• Confirmation: Ultrasound
• Treatment:
• Usually small and no consequence
• USG guided compression/Surgical closure if:
Significant shunt
Extreme swelling and tenderness
CHF, DVT
24. • Treatment:
• Angiography of affected extremity with access
from another extremity
• Dissection requires stenting or surgery
• Thromboembolism can be treated with
surgical(Fogarty catheter) or percutaneous
mechanical thrombectomy (Possis angiojet)
28. Discharge instructions
• Physical activity after the procedure
• Dietary and Lifestyle advice
• Need for additional laboratory testing
afterwards
• Follow up
29. Activity Level
• Should refrain from physical exercise for 48
hours after procedure
• Should refrain from driving for 48 hours after
procedure
• Should refrain from sexual activity for 1 week
after procedure to allow access site healing
• AHA consensus statement: sexual activity is
reasonable for patients at low risk for
cardiovascular complications and for those who
can exercise for 3 to 5 METs without symptoms
or ECG changes
30. Dietary and lifestyle advice
• Heart healthy diet ( fruits, vegetables, whole
grain, low fat dairy products, skinless poultry
and fish, nuts and legumes, non tropical
vegetable oil)
• Weight reduction in obese
• Avoid smoking, alcohol
• Increased physical activity
• Limit saturated fat, trans fat, extra salt, red
meat, sweets and sugar-sweetened beverages
31. Return to work
• Decision to return to work is individualized
Type of work the patient performs
Physical demands
Mental stress
Safety considerations
Job satisfaction
Employer policies
32.
33. Follow UP
• Timing: 2-4 weeks after the procedure
Sooner for patients with
- Procedural complications
- Anaemia
- Renal dysfunction
34. Purpose of follow-up visit
• To ensure compliance with the medication
regimen, especially with regard to DAPT
• To reinforce aggressive secondary prevention
measures, including dietary and exercise
habits and smoking cessation
• To confirm that the patient has enrolled in a
cardiac rehabilitation programme
35. Post PCI medication
• Continue DAPT as per guideline
• Continue other medication as appropriate
• If indication for oral anticoagulant
-Start NOAC the next day
-Start warfarin immediately with a F/U
PT(INR) within 1 week
• If renal impairment Metformin should be
started after renal function returns to normal