This document discusses portfolio management for R&D and new product commercialization. It begins by explaining why portfolio management is important for R&D, as R&D produces a revenue stream and is an investment that companies aim to maximize returns on. It then discusses portfolio management best practices, including using a top-down and bottom-up approach to define the portfolio. Examples are provided of how one company used portfolio management over 9 years on a product line, generating $100 million in cumulative savings. It concludes by discussing first steps to transitioning to a balanced, prioritized portfolio.