This document discusses several types of phytopharmaceuticals, including carotenoids, limonoids, saponins, and flavonoids. It provides details on the occurrence, isolation, characteristics, chemical structures, uses, and health benefits of specific examples within each class, such as α-carotene, β-carotene, xanthophyll, d-limonene, α-terpineol, shatavarins, resveratrol, rutin, hesperidin, naringin, and quercetin. The document aims to comprehensively cover phytopharmaceuticals and their properties and applications in health.
A purified and standardized fraction with a defined minimum of four bioactive or phytochemical compounds of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation, or prevention of any diseases but does not include administration by parenteral route.
The document summarizes the biosynthesis of bacosides, which are active constituents found in Brahmi (Bacopa monniera). Bacosides such as Bacoside A and Bacoside B are triterpenoid saponins derived from the mevalonic acid pathway. This involves acetyl-CoA being converted to mevalonic acid and then isopentenyl pyrophosphate (IPP), from which geranyl pyrophosphate (GPP) and farnesyl pyrophosphate (FPP) are formed. FPP then acts as a substrate for squalene synthase to produce squalene, which is then oxidized and undergoes cyclization to form
Plants Drug Cultivation:
General introduction to importance pharmacognosy.
Indian Council of Agricultural Research.
Current good agricultural practices.
Current good cultivation practices
Current good collection practices.
Conservation of medicinal plants-Ex-situ & In-situ conservation of medicinal plants.
Pharmacognosy is the objective study of crude drugs of animal, vegetable and mineral origin, treated scientifically.
Pharmacognosy is the study of medicine derived from natural sources that include plants, animals, and microorganisms, and the scope of the field depends on knowledge about the safety, purity, and efficacy of complex multicompound products.
Herbal pharmacognosy is the application of this science specifically to traditional herbal medicine sources.
Marine natural products can be defined as biologically active products such as secondary metabolites, enzymes, lipids, and heteropolysaccharides.
Marine Pharmacognosy is a sub-branch of pharmacognosy which is mainly concerned with the naturally occurring substances of medicinal value from the marine.
Marine macroalgae/seaweed is used as a crude drug to treat iodine deficiency-Goitre, hypothyroidism, for Example- Nori seaweed, Kombu, etc.
Establishing a herbal drug industry requires navigating complex regulatory requirements related to safety, efficacy, quality and public health. Key aspects include complying with Good Manufacturing Practices, obtaining product licenses by submitting data on safety and efficacy to regulatory authorities, adhering to labeling and packaging guidelines, implementing quality control testing, monitoring adverse events, and ensuring compliance with international standards such as those of the International Conference on Harmonisation. Meeting these regulatory standards contributes to the success, credibility and public health impact of the herbal drug industry.
Marine natural products are drugs obtained from marine organisms that have been studied since ancient times. The oceans cover most of the earth's surface and are home to a vast diversity of species, many of which are still unknown. Marine organisms produce unique biochemical adaptations for survival in extreme conditions that could provide benefits for pharmacology. However, issues like limited supply, taxonomic identification challenges, and screening large numbers of microbes associated with invertebrates present obstacles for drug development from marine sources. Improved genetic engineering, databases, and activity-based screening methods may help address these problems and unlock the potential of marine organisms for new pharmaceuticals.
Unit I: Plant Drug Cultivation
General introduction to the importance of
Pharmacognosy in herbal drug industry, Indian Council of
Agricultural Research, Current Good Agricultural Practices,
Current Good Cultivation Practices, Current Good Collection
Practices, Conservation of medicinal plants- Ex-situ and Insitu
conservation of medicinal plants.
A purified and standardized fraction with a defined minimum of four bioactive or phytochemical compounds of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation, or prevention of any diseases but does not include administration by parenteral route.
The document summarizes the biosynthesis of bacosides, which are active constituents found in Brahmi (Bacopa monniera). Bacosides such as Bacoside A and Bacoside B are triterpenoid saponins derived from the mevalonic acid pathway. This involves acetyl-CoA being converted to mevalonic acid and then isopentenyl pyrophosphate (IPP), from which geranyl pyrophosphate (GPP) and farnesyl pyrophosphate (FPP) are formed. FPP then acts as a substrate for squalene synthase to produce squalene, which is then oxidized and undergoes cyclization to form
Plants Drug Cultivation:
General introduction to importance pharmacognosy.
Indian Council of Agricultural Research.
Current good agricultural practices.
Current good cultivation practices
Current good collection practices.
Conservation of medicinal plants-Ex-situ & In-situ conservation of medicinal plants.
Pharmacognosy is the objective study of crude drugs of animal, vegetable and mineral origin, treated scientifically.
Pharmacognosy is the study of medicine derived from natural sources that include plants, animals, and microorganisms, and the scope of the field depends on knowledge about the safety, purity, and efficacy of complex multicompound products.
Herbal pharmacognosy is the application of this science specifically to traditional herbal medicine sources.
Marine natural products can be defined as biologically active products such as secondary metabolites, enzymes, lipids, and heteropolysaccharides.
Marine Pharmacognosy is a sub-branch of pharmacognosy which is mainly concerned with the naturally occurring substances of medicinal value from the marine.
Marine macroalgae/seaweed is used as a crude drug to treat iodine deficiency-Goitre, hypothyroidism, for Example- Nori seaweed, Kombu, etc.
Establishing a herbal drug industry requires navigating complex regulatory requirements related to safety, efficacy, quality and public health. Key aspects include complying with Good Manufacturing Practices, obtaining product licenses by submitting data on safety and efficacy to regulatory authorities, adhering to labeling and packaging guidelines, implementing quality control testing, monitoring adverse events, and ensuring compliance with international standards such as those of the International Conference on Harmonisation. Meeting these regulatory standards contributes to the success, credibility and public health impact of the herbal drug industry.
Marine natural products are drugs obtained from marine organisms that have been studied since ancient times. The oceans cover most of the earth's surface and are home to a vast diversity of species, many of which are still unknown. Marine organisms produce unique biochemical adaptations for survival in extreme conditions that could provide benefits for pharmacology. However, issues like limited supply, taxonomic identification challenges, and screening large numbers of microbes associated with invertebrates present obstacles for drug development from marine sources. Improved genetic engineering, databases, and activity-based screening methods may help address these problems and unlock the potential of marine organisms for new pharmaceuticals.
Unit I: Plant Drug Cultivation
General introduction to the importance of
Pharmacognosy in herbal drug industry, Indian Council of
Agricultural Research, Current Good Agricultural Practices,
Current Good Cultivation Practices, Current Good Collection
Practices, Conservation of medicinal plants- Ex-situ and Insitu
conservation of medicinal plants.
Drug discovery is the process through which potential new medicines are identified.
It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology.
Natural products and their structural analogues have historically made a major contribution to pharmacotherapy, especially for cancer and infectious diseases.
Natural products also have challenges for drug discovery, such as technical barriers to screening, isolation, characterization and optimization.
INDIAN AND INTERNATIONAL PATENT LAW AS APPLICABLE TO HERBAL AND NATURAL PRODUCTSTejaswini Chandra
This document discusses intellectual property rights and patent laws related to industrial pharmacognosy. It defines intellectual property rights as protections for an inventor's intellectual creations. Patents provide exclusive rights over an invention for a limited time in exchange for public disclosure. The history of patent law in India traces back to 1911. For an invention to be patentable, it must be novel, involve an inventive step, and have industrial application. Natural products can be patented if they involve new processes, formulations, or uses. International treaties like the Patent Cooperation Treaty allow filing a single international patent application.
Withanolides are a group of at least 300 naturally occurring steroids built on an ergostane skeleton.They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo.
Structurally, withanolides consist of a steroid backbone bound to a lactone or one of its derivatives; they are produced via oxidation of steroids. It remains unknown to what end withanolides are produced; they may act as a deterrent for feeding insect larvae and other herbivores
This document discusses several natural health drinks including acai berry juice, green tea, goji berry juice, noni fruit juice, amla juice, and wheatgrass juice. It describes the source and botanical information for each drink, provides their nutritional composition, and lists their various health benefits such as increased energy, improved immune function, antioxidant effects, and more. The document concludes by citing several references for further information on the health impacts of these natural beverages.
This document provides information about withanolides and umbelliferone. It discusses their biological sources, properties, biosynthesis, extraction, isolation, uses, and characterization. Withanolides are steroidal lactones found in ashwagandha that have anti-cancer and anti-inflammatory properties. Umbelliferone is a yellow coumarin found in plants like carrot and coriander that exhibits blue fluorescence and is used as an indicator in chemical tests. The document outlines methods for extracting, isolating, and identifying these compounds using techniques like column chromatography, TLC, UV-Vis, IR, NMR, and mass spectroscopy.
A patent is an exclusive right granted for an invention, which is a product or a process that provides, in general, a new way of doing something, or offers a new technical solution to a problem.
To get a patent, technical information about the invention must be disclosed to the public in a patent application.
The patent is usually referred to as the right granted to an inventor for his Invention of any new, useful, non-obvious process, machine, article of manufacture, or composition of matter
1. The document discusses the structure elucidation of various compounds including carvone, citral, menthol, luteolin, kaempferol, nicotine, caffeine, and glycyrrhizin.
2. Various analytical techniques are described such as UV, IR, mass spectroscopy, and NMR that are used to determine the structure of these compounds.
3. The uses of these compounds are also mentioned including as flavorings, fragrances, medicines, and supplements.
The document discusses various types of nutraceuticals, including inorganic mineral supplements like calcium, magnesium, and zinc; vitamin supplements; digestive enzymes; dietary fibers; cereals and grains; antioxidants; polyunsaturated fatty acids; health drinks from natural sources like fruits, tea, and soy; and wines. It provides examples and health benefits of each category in 1-3 sentences and covers a wide range of nutraceutical topics over 12 pages.
INDUSTRIAL PHARMACOGNOSTICAL TECHNOLOGY
Herbal drug industry: Infrastructure of herbal drug industry
involved in production of standardized extracts and various
dosage forms. Current challenges in upgrading and
modernization of herbal formulations. Entrepreneurship
Development, Project selection, project report, technical
knowledge, Capital venture, plant design, layout and construction.
Pilot plant scale –up techniques, case studies of herbal extracts.
Formulation and production management of herbals.
Pharmacovigilance of drugs of natural origin.pdfKipaPape
PHARMACOVIGILANCE OF DRUGS OF NATURAL ORIGIN.
WHO AND AYUSH GUIDELINES FOR SAFETY MONITORING OF NATURAL MEDICINE.
SPONTANEOUS REPORTING SCHEMES FOR BIODRUG ADVERSE REACTIONS
BIO DRUG-DRUG AND BIO DRUG-FOOD INTERACTIONS WITH SUITABLE EXAMPLES
Pharmacovigilance is the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or any other medicine/vaccine-related problem.
All medicines and vaccines undergo rigorous testing for safety and efficacy through clinical trials before they are authorized for use.
The clinical trial process involves studying these products in a relatively small number of selected individuals for a short period of time.
Certain side effects may only emerge once these products have been used by a heterogenous population, including people with other concurrent diseases, and over a long period.
Regulatory requirement for setting herbal drug industryRAGHAV DOGRA
The World Health Organization (WHO) estimates that 80 percent of the population of some Asian and African countries presently use herbal medicine for some aspect of primary health care.Pharmaceuticals are prohibitively expensive for most of the world's population, half of whom lived on less than $2 U.S. per day in 2002. In comparison, herbal medicines can be grown from seed or gathered from nature for little or no cost
patent (/ˈpætənt/ or /ˈpeɪtənt/) is a set of exclusive rights granted by a sovereign state to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention. An invention is a solution to a specific technological problem and is a product or a process. Patents are a form of intellectual property.
This topic covers the notes for unit 1 of phytochemistry in 1st semester in M Pharm of department of pharmacognosy. This includes biosynthesis, characterization, purification and uses of steroids.
Monographs Of Herbal Drugs and Comparative Study In Various Pharmacopoeias.VidyaNani
This document provides a comparison of herbal monographs from three pharmacopoeias: the Ayurvedic Pharmacopoeia of India (API), British Herbal Pharmacopoeia (BHP), and American Herbal Pharmacopoeia (AHP). It outlines the typical contents of monographs from each, such as definitions, descriptions, chemical assays, and qualitative standards. The API focuses on ayurvedic herbs, while the BHP and AHP include Western and traditional medicine herbs. The AHP contains the most therapeutic information, while the API and BHP emphasize identification and purity. Harmonizing formats across pharmacopoeias can help ensure the quality, safety and efficacy of herbal medicines.
As per the m. Pharmacy 1st year syllabus, this presentation includes all the information about "Marine natural products" such as detailed introduction, classification of marine drugs, general method of isolation and purification, detailed introduction and use of marine toxins. The source or reference of books/auther are included in last slide.
Ethnobotany and ethnopharmacology involve the scientific study of how different ethnic groups use plants for medicinal purposes. The document discusses the impact of ethnobotany on herbal drug evaluation and traditional medicine. It describes how ethnobotany helps identify new plant-based drugs and molecular models through processes like bioassay-guided purification and structure elucidation. Ethnopharmacology plays a key role in evaluating traditionally used herbal medicines and validating their therapeutic effects through controlled clinical studies.
The document discusses monographs of herbal drugs from the Siddha and Unani pharmacopoeias. It provides an overview of the Unani pharmacopoeia of India and its monograph format, including sections on nomenclature, description, tests, and specifications. An example of a Unani monograph is given for Habb-e-Mudir. The Siddha pharmacopoeia of India and its monograph format are also reviewed, along with an example Siddha monograph for Amukkaru. References are provided at the end.
Phytochemical fingerprinting by hptlc and gc msChetna Kaushik
The document discusses phytochemical fingerprinting using techniques like high performance thin layer chromatography (HPTLC) and gas chromatography-mass spectrometry (GC-MS). It provides details on the principles, methodology, and applications of HPTLC for obtaining chromatographic fingerprints of plant extracts. These fingerprints can characterize samples based on the retention factor values and profiles of constituents. The document also describes the basic components and working of GC-MS, a hyphenated technique useful for identification of compounds in a sample.
monographs of herbal drugs I.P, U.S.P, A.H.P, B.P..pptxSurendra Chowdary
This document provides a summary of monographs from various pharmacopoeias including the Indian Pharmacopoeia (IP), United States Pharmacopeia (USP), American Herbal Pharmacopoeia (AHP), and British Pharmacopoeia (BP). It defines what a pharmacopoeia and monograph are, and describes the typical format and components of monographs from each pharmacopoeia. Examples of monographs for ashwagandha from IP and banaba leaf from USP are also provided to illustrate the monograph formats.
coumarin; umbelliferone and its biosynthesis and isolation.
terpenoide; cucurbitacine and its biosynthesis and isolation purification and characterization
This document provides information on a nutritional supplement product. It describes the product as containing a unique blend of over 100 nutrients including fruits, vegetables, mushrooms, enzymes, fatty acids, and other ingredients. The supplement is claimed to have various health benefits such as boosting immunity, supporting cardiovascular health, and reducing risks of cancer and other diseases. Manufacturing and other details are also provided.
Oppoutunity Presentation AIM Global Nigeria official Presenationsamiben4u
- This is a presentation for a multi-level marketing company established in 2006 with offices internationally.
- It provides information on the company's executives and awards received for its nutritional supplements.
- The company produces over 700 product lines including supplements with antioxidants, probiotics, and essential fatty acids shown to have health benefits.
- The document outlines the company's marketing and compensation plan which allows distributors to earn retail profits and bonuses through sales and by building a team.
Drug discovery is the process through which potential new medicines are identified.
It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology.
Natural products and their structural analogues have historically made a major contribution to pharmacotherapy, especially for cancer and infectious diseases.
Natural products also have challenges for drug discovery, such as technical barriers to screening, isolation, characterization and optimization.
INDIAN AND INTERNATIONAL PATENT LAW AS APPLICABLE TO HERBAL AND NATURAL PRODUCTSTejaswini Chandra
This document discusses intellectual property rights and patent laws related to industrial pharmacognosy. It defines intellectual property rights as protections for an inventor's intellectual creations. Patents provide exclusive rights over an invention for a limited time in exchange for public disclosure. The history of patent law in India traces back to 1911. For an invention to be patentable, it must be novel, involve an inventive step, and have industrial application. Natural products can be patented if they involve new processes, formulations, or uses. International treaties like the Patent Cooperation Treaty allow filing a single international patent application.
Withanolides are a group of at least 300 naturally occurring steroids built on an ergostane skeleton.They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo.
Structurally, withanolides consist of a steroid backbone bound to a lactone or one of its derivatives; they are produced via oxidation of steroids. It remains unknown to what end withanolides are produced; they may act as a deterrent for feeding insect larvae and other herbivores
This document discusses several natural health drinks including acai berry juice, green tea, goji berry juice, noni fruit juice, amla juice, and wheatgrass juice. It describes the source and botanical information for each drink, provides their nutritional composition, and lists their various health benefits such as increased energy, improved immune function, antioxidant effects, and more. The document concludes by citing several references for further information on the health impacts of these natural beverages.
This document provides information about withanolides and umbelliferone. It discusses their biological sources, properties, biosynthesis, extraction, isolation, uses, and characterization. Withanolides are steroidal lactones found in ashwagandha that have anti-cancer and anti-inflammatory properties. Umbelliferone is a yellow coumarin found in plants like carrot and coriander that exhibits blue fluorescence and is used as an indicator in chemical tests. The document outlines methods for extracting, isolating, and identifying these compounds using techniques like column chromatography, TLC, UV-Vis, IR, NMR, and mass spectroscopy.
A patent is an exclusive right granted for an invention, which is a product or a process that provides, in general, a new way of doing something, or offers a new technical solution to a problem.
To get a patent, technical information about the invention must be disclosed to the public in a patent application.
The patent is usually referred to as the right granted to an inventor for his Invention of any new, useful, non-obvious process, machine, article of manufacture, or composition of matter
1. The document discusses the structure elucidation of various compounds including carvone, citral, menthol, luteolin, kaempferol, nicotine, caffeine, and glycyrrhizin.
2. Various analytical techniques are described such as UV, IR, mass spectroscopy, and NMR that are used to determine the structure of these compounds.
3. The uses of these compounds are also mentioned including as flavorings, fragrances, medicines, and supplements.
The document discusses various types of nutraceuticals, including inorganic mineral supplements like calcium, magnesium, and zinc; vitamin supplements; digestive enzymes; dietary fibers; cereals and grains; antioxidants; polyunsaturated fatty acids; health drinks from natural sources like fruits, tea, and soy; and wines. It provides examples and health benefits of each category in 1-3 sentences and covers a wide range of nutraceutical topics over 12 pages.
INDUSTRIAL PHARMACOGNOSTICAL TECHNOLOGY
Herbal drug industry: Infrastructure of herbal drug industry
involved in production of standardized extracts and various
dosage forms. Current challenges in upgrading and
modernization of herbal formulations. Entrepreneurship
Development, Project selection, project report, technical
knowledge, Capital venture, plant design, layout and construction.
Pilot plant scale –up techniques, case studies of herbal extracts.
Formulation and production management of herbals.
Pharmacovigilance of drugs of natural origin.pdfKipaPape
PHARMACOVIGILANCE OF DRUGS OF NATURAL ORIGIN.
WHO AND AYUSH GUIDELINES FOR SAFETY MONITORING OF NATURAL MEDICINE.
SPONTANEOUS REPORTING SCHEMES FOR BIODRUG ADVERSE REACTIONS
BIO DRUG-DRUG AND BIO DRUG-FOOD INTERACTIONS WITH SUITABLE EXAMPLES
Pharmacovigilance is the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or any other medicine/vaccine-related problem.
All medicines and vaccines undergo rigorous testing for safety and efficacy through clinical trials before they are authorized for use.
The clinical trial process involves studying these products in a relatively small number of selected individuals for a short period of time.
Certain side effects may only emerge once these products have been used by a heterogenous population, including people with other concurrent diseases, and over a long period.
Regulatory requirement for setting herbal drug industryRAGHAV DOGRA
The World Health Organization (WHO) estimates that 80 percent of the population of some Asian and African countries presently use herbal medicine for some aspect of primary health care.Pharmaceuticals are prohibitively expensive for most of the world's population, half of whom lived on less than $2 U.S. per day in 2002. In comparison, herbal medicines can be grown from seed or gathered from nature for little or no cost
patent (/ˈpætənt/ or /ˈpeɪtənt/) is a set of exclusive rights granted by a sovereign state to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention. An invention is a solution to a specific technological problem and is a product or a process. Patents are a form of intellectual property.
This topic covers the notes for unit 1 of phytochemistry in 1st semester in M Pharm of department of pharmacognosy. This includes biosynthesis, characterization, purification and uses of steroids.
Monographs Of Herbal Drugs and Comparative Study In Various Pharmacopoeias.VidyaNani
This document provides a comparison of herbal monographs from three pharmacopoeias: the Ayurvedic Pharmacopoeia of India (API), British Herbal Pharmacopoeia (BHP), and American Herbal Pharmacopoeia (AHP). It outlines the typical contents of monographs from each, such as definitions, descriptions, chemical assays, and qualitative standards. The API focuses on ayurvedic herbs, while the BHP and AHP include Western and traditional medicine herbs. The AHP contains the most therapeutic information, while the API and BHP emphasize identification and purity. Harmonizing formats across pharmacopoeias can help ensure the quality, safety and efficacy of herbal medicines.
As per the m. Pharmacy 1st year syllabus, this presentation includes all the information about "Marine natural products" such as detailed introduction, classification of marine drugs, general method of isolation and purification, detailed introduction and use of marine toxins. The source or reference of books/auther are included in last slide.
Ethnobotany and ethnopharmacology involve the scientific study of how different ethnic groups use plants for medicinal purposes. The document discusses the impact of ethnobotany on herbal drug evaluation and traditional medicine. It describes how ethnobotany helps identify new plant-based drugs and molecular models through processes like bioassay-guided purification and structure elucidation. Ethnopharmacology plays a key role in evaluating traditionally used herbal medicines and validating their therapeutic effects through controlled clinical studies.
The document discusses monographs of herbal drugs from the Siddha and Unani pharmacopoeias. It provides an overview of the Unani pharmacopoeia of India and its monograph format, including sections on nomenclature, description, tests, and specifications. An example of a Unani monograph is given for Habb-e-Mudir. The Siddha pharmacopoeia of India and its monograph format are also reviewed, along with an example Siddha monograph for Amukkaru. References are provided at the end.
Phytochemical fingerprinting by hptlc and gc msChetna Kaushik
The document discusses phytochemical fingerprinting using techniques like high performance thin layer chromatography (HPTLC) and gas chromatography-mass spectrometry (GC-MS). It provides details on the principles, methodology, and applications of HPTLC for obtaining chromatographic fingerprints of plant extracts. These fingerprints can characterize samples based on the retention factor values and profiles of constituents. The document also describes the basic components and working of GC-MS, a hyphenated technique useful for identification of compounds in a sample.
monographs of herbal drugs I.P, U.S.P, A.H.P, B.P..pptxSurendra Chowdary
This document provides a summary of monographs from various pharmacopoeias including the Indian Pharmacopoeia (IP), United States Pharmacopeia (USP), American Herbal Pharmacopoeia (AHP), and British Pharmacopoeia (BP). It defines what a pharmacopoeia and monograph are, and describes the typical format and components of monographs from each pharmacopoeia. Examples of monographs for ashwagandha from IP and banaba leaf from USP are also provided to illustrate the monograph formats.
coumarin; umbelliferone and its biosynthesis and isolation.
terpenoide; cucurbitacine and its biosynthesis and isolation purification and characterization
This document provides information on a nutritional supplement product. It describes the product as containing a unique blend of over 100 nutrients including fruits, vegetables, mushrooms, enzymes, fatty acids, and other ingredients. The supplement is claimed to have various health benefits such as boosting immunity, supporting cardiovascular health, and reducing risks of cancer and other diseases. Manufacturing and other details are also provided.
Oppoutunity Presentation AIM Global Nigeria official Presenationsamiben4u
- This is a presentation for a multi-level marketing company established in 2006 with offices internationally.
- It provides information on the company's executives and awards received for its nutritional supplements.
- The company produces over 700 product lines including supplements with antioxidants, probiotics, and essential fatty acids shown to have health benefits.
- The document outlines the company's marketing and compensation plan which allows distributors to earn retail profits and bonuses through sales and by building a team.
This document summarizes information about various carotenoids and polyphenols. It discusses their characteristics, uses, health benefits, and sources. Carotenoids are organic pigments found in plants and photosynthetic organisms. Over 600 are known, with beta-carotene, alpha-carotene, gamma-carotene, and beta-cryptoxanthin having vitamin A activity in humans. Polyphenols include flavonoids and tannins. Flavonoids include anthocyanidins, flavanols, flavones, and flavonones. They have antioxidant, anti-inflammatory, and other health benefits. Sources include fruits, vegetables, tea, cocoa. The document provides details on compounds
Present by: Minar Mahmoud M. Hassanein
National Research Centre, Food Industries and Nutrition, Fats and Oils Dept. Egypt
in workshop on Workshop on Oleochemicals at the SemiRamis Intercontinental Hotel.
This document summarizes the benefits of several natural health supplements. It describes a complete nutritional supplement that contains antioxidants, vitamins, minerals, fruits and vegetables. It also discusses supplements that support heart health with omega-3 fatty acids, promote anti-aging effects with resveratrol, aid weight loss, brighten skin appearance, and boost energy levels with B vitamins. The supplements are produced by a top manufacturing company and provide numerous benefits for overall health and wellness.
This document discusses phytochemicals, which are compounds found in plants that provide health benefits to humans. It defines phytochemicals and describes some of their main functions, including antioxidant and anti-inflammatory properties. The document then examines several types of phytochemicals in depth, including carotenoids, phenolic acids, flavonoids, terpenoids, and curcuminoids, and discusses their sources and health benefits.
Nutritional quality and chemical composition of fruits.pptxglorysunny
This document discusses the nutritional quality and chemical composition of several fruits: banana, plantain, apple, grapes, mango, orange, pear, and pineapple. It provides information on the vitamins, minerals, antioxidants, dietary fiber, carbohydrates, and other components found in each fruit. Key nutritional elements highlighted include potassium, vitamin C, antioxidants like flavonoids, and health benefits such as reducing risk of cancer and heart disease. The chemical compounds responsible for the flavors and aromas of some fruits are also mentioned.
Vitamin K plays an essential role in blood clotting and bone health. It exists in two primary forms, K1 and K2, with K2 having greater potency and a wider range of functions. Key sources of vitamin K include green leafy vegetables, fermented foods like natto, and bacteria in the intestines. Adequate vitamin K is required for blood clotting by enabling the liver to synthesize clotting proteins, as well as supporting bone mineralization and vascular health.
The document discusses vitamins, providing details on vitamins A, D, E, and K. It defines what vitamins are, their classifications, functions, sources, deficiencies, toxicity, and assays for analyzing levels. The document serves as an in-depth review and analysis of several important fat-soluble vitamins.
This document summarizes quality control procedures for the herbal mixture SEKEM Renal used to treat renal conditions. It describes 7 herbs in the mixture - licorice root, chicory leaves, peppermint leaves, ammi visnaga fruits, and their structures, constituents, purity tests, and analytical methods. The document provides details on organoleptic properties, microscopic characteristics, extractive values, pesticide residues, heavy metals content and HPLC/GC-MS analytical methods for evaluating the herbs in the mixture.
Flavonoids are a class of plant secondary metabolites that are found widely in fruits, vegetables, grains, bark, roots, stems, flowers, and tea. They have beneficial effects on health such as anti-oxidative, anti-inflammatory, and anti-cancer properties. There are different types of flavonoids including flavonoids, isoflavonoids, and neoflavonoids which are derived from varying chemical structures. Quercetin, epicatechin, and proanthocyanidins are examples of flavonoids that have anti-inflammatory, antioxidant, and effects on blood flow and collagen. Good sources of flavonoids include citrus fruits, berries, onions, tea, and dark chocolate.
Life is valuable! We want to stay healthy or live longer. Nobody wants to get sick or die at a young age especially if you worked hard to become successful in life. You want to live longer to enjoy the fruits of your labor. Avail our products to stay fit and healthy. Prevention is the best medicine and better than cure.
11 Reasons to Take Ole Olive Leaf Extract by QNETQNET Ltd
The document summarizes information about olive leaf extract including:
- It contains powerful antioxidants and polyphenols that support immune function and combat free radicals.
- The extract in this product comes from a specially selected olive variety grown in Australia that provides high levels of antioxidants.
- The leaves are harvested and processed immediately to retain maximum potency as an extract with no drying or storage.
Features & Application of CaliVita dietary supplementsMarta Kinga Veres
The top reasons why it is important to take natural supplements:
- Increasing levels of environmental pollution in our air, water and food
- Depleted soils
- A study published in the Journal of Nutrition and Health found copper levels in the UK have dropped by 90% in dairy, 55% in meat, and 76% in vegetables from 1940 - 2002.
- Food processing, cooking, and preserving
- Normal Aging = Digestion Issues
- Stress + Stress + Stress = Compromised Immune System
CaliVita food supplements:
- They are made from fresh natural ingredients and contain no chemical additives (sugar, salt, preservatives, artificial colors or genetically modified components)
- Delayed release technology
- Synergic (mutually strengthening) effect
- They are manufactured in the USA under the controll of US Food and Drug Administration, according to the principles of GMP (Good Manufacturing Practice)
You can buy Calivita products here: https://martaveres.calivita.eu/webshop
The survey by the National Nutrition Monitoring Bureau indicates that vitamins are essential nutrients that must be obtained through diet as they cannot be synthesized by the body. It provides information on the common sources and recommended daily allowances of important water-soluble vitamins like thiamine, riboflavin, niacin, and folic acid as well as fat-soluble vitamins A, D, and C. Deficiency in these vitamins can result in various diseases which are described in the document.
The document discusses various bioactive compounds found in fruits and vegetables, including carotenoids, polyphenols, vitamins, and anthocyanins. It provides details on specific compounds like beta-carotene, lycopene, lutein, and zeaxanthin, and explains their health benefits. These compounds are said to be responsible for the colors of fruits and vegetables and may help prevent diseases. The document also discusses vitamins A, D, E, K, C, and B12, and their roles and food sources.
This document summarizes the medicinal properties of Carica papaya (papaya). It discusses the plant's taxonomy and components like vitamins and enzymes. Different parts of the plant like fruits, leaves, seeds and latex are used to treat various diseases. The fruit aids digestion and contains antioxidants that may prevent cancer and heart disease. Papaya leaf juice increases platelet count and is used to treat dengue fever. Extract from the leaves, seeds and latex exhibit antimicrobial and wound healing properties. In conclusion, Carica papaya is an important medicinal plant used to treat many ailments in traditional medicine.
nutritional supplemen and fat soluble .pptxPawanMaharjan4
Vitamin D is a secosteroid produced in the skin from 7-dehydrocholesterol under UV light or obtained from dietary sources like fish, eggs, and mushrooms. It is stored in the liver and adipose tissue and functions to increase intestinal absorption of calcium and phosphate which is necessary for bone formation and mineralization. Vitamin D deficiency can lead to rickets in children, causing soft bones and deformities, and osteomalacia in adults, causing skeletal pain and porous bones. It has a recommended daily intake of 600-800 IU and is used to treat and prevent rickets, osteoporosis, and hypocalcemia.
Grape seed oil has various uses for cooking, cosmetics, and medicine. It has a neutral taste and high smoke point, making it suitable for cooking. Cosmetically, it helps repair skin and reduce signs of aging and stress. Medicinally, it may help reduce high cholesterol, blood pressure, and support heart health. Grape seed extract contains antioxidants like oligomeric proanthocyanidins (OPCs) which reduce free radical damage in the body.
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central19various
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
2. A. Carotenoids:
1. α and β –carotene:
• Occurrence: Chromoplast of plant algae fungi & bacteria.
• Isolation of carotenoids:
Isopentenyl pyrophosphate(IPP)
Dimethylallyl pyrophosphate
Geranyl phosphate
Fernesyl phosphate
Geranyl geranyl pyrophosphate
Phytoene
Lycopene
α-Carotene β-Carotene
3. α-Carotene:
• Characteristic features:
- It has provide to be almost ten fold more anti-carcinogenic in comparison to
β-carotene.
- It distinictly increases the release of immunogenic IL-1** and TNF-α.***
• Chemical nature:
α-Carotene
4. β-Carotene:
• Characteristic features:
- It is weak antioxidant, but prove to be strong against singlet oxygen.
- The supplements may enrich LDL-cholesterol-β-carotene content without
affecting other carotene variants e.g.,α-carotene;𝛾 − 𝑐𝑎𝑟𝑜𝑡𝑒𝑛𝑒.
- It may significantly boost cause stimulation for the activity of Natural Killer
(NK) immune cells.
- It may appreciably cause stimulation for the DNA-repair enzymes.
- It definitely provides distinctly better cornea protection against the harmful
UV- radiation in comparison to lycopene.
• Chemical nature:
Β-Carotene
5. Uses of α-carotene:
-Cardiovascular diseases
-Cancer
-Diabetes
-Chronic lower respiratory disease
Uses of β-carotene:
-Breast cancer
-Preventing complication of lung disease
-Osteoarthritis
-Ovarian cancer
-Sunburn
-Psoriasis
-Schizophrenia
-Epilepsy
6. • Health benefits:
-Protection from free radicals.
-Decreases risk of cardiovascular disease.
-Prevents oral cavity and lung cancer.
-Increases sperm production.
-Maintenance of epithelial functions.
7. 2. Xanthophyll (Lutein):
•Occurrence:
- Xanthophyll is very widely distributed in nature and is found (either free or
as an ester) along with carotenes and chlorophyll in green parts of plants.
- Other important sources are red and yellow blossoms, xanthophyll
combined with protein is also found in some green insects.
8. Isolation:
Material is dried ground and extracted firstly with 80% methanol and then with ether.
Extract diluted with water saponified with methanolic potassium hydroxide.
Wash to remove excess of alkali.
Solvents removed by distillation and residue cooled when crystals of xanthophyll
separate out.
More quantity of xanthophyll is obtained from mother liquor by concentration and
extraction with petroleum ether.
The pigment is purified by chromatography using zinc carbonate as adsorbent and
benzene as solvent.
9. • Characteristic features:
-Xanthophylls are important by virtue of the fact that they seem to cause protection of
vitamin A, vitamin E and other carotenoids from undergoing oxidation in vivo.
-Substantial evidence is emerging gradually that xanthophyll are highly tissue specific.
-Lutein and Xanthophyll almost comprise of nearly 50% of all carotenoids present
strategically in the retina.
-It may also render protection against colon cancer.
-It impact ‘yellow colour’ to avocado, corn and yolk of an egg.
• Uses:
-Prevention of colon cancer, breast cancer, type 2 diabetes and heart disease.
-supports overall eye health.
-Acts as a great antioxidant.
-It has been shown to boost immunity.
-Supports healthy skin, tissues and blood.
11. • Health benefits:
- Acting as antioxidant.
- Boosting your blood.
- Boosting your eyes.
- Boosting your immune system.
- Boosting your reproductive health.
- Preventing arthritis.
- Preventing disorders.
12. B. Limonoids:
1. d-Limonene:
• Occurrence:
-The limonoids are particularly found in the peels of serval citrus fruits e.g. oranges,
mandarins, lemons, grape fruits etc.
• Isolation:
-Swietenia macrophylla king
- Seeds crude extract
-Antimicrobial screening
-Dissolved in 5%MeOH in water
-Successive fractionation ( on the basis of polarity)
Chloroform fraction, ethyl acetate fraction, aqueous fraction
-Antimicrobial activity
-Most active fraction
-Isolation and identification :HPLC, MS,FTIR, NMR
-Minimum inhibitory concentration
13. • Characteristic features:
- d-limonene is found to be 45 times more anticarcinogenic in comparison to
hesperidin.
- It specifically detoxifies the carcinogenic substances, and thereby promotes
the ensuing cancer cell apoptosis.
- Limonene distinctly helps to promote the ‘glutathione-s-transferase’ i.e.,refers
to detoxification by glutathione addition.
- d-limonene has a distinct orange like smell.
• Chemical nature:
d-limonene
14. • Uses:
- Used to make medicine.
- It is used to promote weight loss, prevent cancer, treat cancer, and treat bronchitis.
- Used as a flavouring.
• Health benefits:
-Boosts immunity
-Improves gallbladder health
-Provides indigestion relief
-Prevents and fights cancers
-Prevents atty livers and insulin resistance
-Kills pathogens/ infections
-Aids in weight loss
-Insomnia
15. 2. α-terpineol:
• Characteristic features:
- α-Terpineol gives rise to the peculiar carrot flavour to the fresh carrots.
- It causes critical arrest of the ‘cell –cycle’ in the neoplasmic cells.
• Chemical nature:
α- terpineol
16. • Uses:
- It is used in the mfg of cosmetics, soaps, perfumes, antiseptic agents.
• Health benefits:
-Antioxidant
-Anticancer
-Anticonvulsant
-Antiulcer
-Antihypertensive
-Anti-nociceptive compound.
17. C. Saponins:
1. Shatavarins:
• Occurrence:
-It consist of dried leaf and leaves of asparagus racemous belongs to family liliaceae.
Commonly known as shatawar, astmuli, etc.found in asia, Africa etc.
• Isolation:
-Collect tuberous root of asparagus rhamnose and produce powder.
-Extracted with hexane.
-Separate and dry extract by maceration with 90% methanol at room temp. for 24 hrs.
-Total methanolic extract was evaporate on water bath to obtained liquid syrup.
-Dissolved in 10% methanol.
-Done column chromatography in which s. phase- silica gel G m. phase – ethyl acetate: methanol:
water(8:1:1)
-Take small amount extract mixture and dry.
-Isolated compound found colour shiny powder.
-Characterization by hptlc, mass.
18. • Characteristics features:
- Used as galactagogue to promote the flow of milk.
- Also employed as tonic and diuretic
• Chemical nature:
Shatavarins
19. • Uses:
-It is used in ayurvedic medicine.
-It is also used to promote milk production in nursing mothers, and for gastric
ulcers and indigestion.
• Health benefits:
- Supports female reproductive system.
- Promotes fertility.
- Aids in digestion.
- Boosts the immune system.
- Boosts energy and strength.
- Stomach ulcer.
- Soothing insomnia.
20. D. Flavonoids:
1.Resveratrol:
• Occurrence:
Resveratrol which can be found in large amounts in the skin of grapes, tomatoes and in red wine.
• Isolation:
Powder of p.capsidatum
95% ethanol extract dried(filtration)
Residue Aq. Solution
liquid-liquid extraction with methyl tert butyl ether
Aq. Phase Organic phase
Aq.phase organic phase
Resveratrol
21. • Characteristic features:
- Grape skin contains polyphenol known for its high antioxidant activity.
- The purple colour of grape skin is of anthocyanin- family polyphenol.
- Resveratrol as a characteristic component of grape has caught people’s
attention.
• Chemical nature:
22. • Uses:
- Acne
- Mental function
- Seasonal allergy
- Cancer
- Diabetes
- Lung disease
- Metabollic syndrome
- Inflamatory bowel syndrome
• Health benefits:
-Increased energy
-Reduced aging
-Anti-inflammatory properties
-Lowers blood sugar
-Increases sperm production
-Cancer prevention
-Protects the cardiovascular system
23. 2.Rutin:
• Occurrence:
Powder of dried food grain of Fagopyrum family polygonaceae.
Constituents:12%protein, 2%pat & rutin.
• Isolation:
Take a leaves of Tridax Procumben L. collected and wash with tap water
Shade dry & formation of powder
25 gm of powder extract with Soxhlet apparatus add 250ml of 80% ethanol
10 ml mix +25 distilled water
Extract with petroleum ether
Again extract with chloroform
After extraction aq layer separate for solution
Left to stand for 22 hr
Yellow PPH formation & separate
PPT dissolved in ethanol
Analyse by HPLC
24. • Characteristic features:
- Rutins is usally found in buckwheat, asparagus, and a variety of citrus fruits
and grapes.
- It has been observed that there is practically very little loss in drying grapes to
raisins.
- Rutin is found to strengthen the capillary walls.
• Chemical nature:
Rutin
25. • Uses:
- Osteoartherities
- Swelling in arm after breast cancer
- Bleeding
- Heamorrhoides
- Blood vessel disease
- Prevention of mouth ulcer
- Varicose veins
• Health benefits:
-Helps blood circulation
-Reduces arthritis
-Strong blood clots
-Prevents blood clots
-Lowers cholesterol
-Antioxidant
26. 3. Hesperidin:
• Occurrence:
Peels of citrus aurantium family Rutaceae.
Constituents : flavonoids
• Isolation:
Extract the dried citrus peel successively with petroleum ether followed by
methanol.
The petroleum ether removes the essential oils in the peel and the methanol
will extract the glycoside.
27. • Characteristic features:
-Hesperidin represents the major flavonoid in oranges and other citrus fruits.
-It serves as an ‘antioxidant’ which helps to regenerated Vitamin C in vivo.
-It gradually slows down the proliferation of the neoplasm(cancer) cells.
-Hesperidin also specifically slows down the replication of various viruses e.g.
influenza, herpes and polio.
• Chemical natures:
Hesperidin
28. • Uses:
-Hypertension
-CVS disorder
-Hemorrhoids
- Varicose veins
• Health benefits:
-Important implication in treatment of cancer.
-Hesperidin in different citrus juices showed antiproliferative activity.
-Lemons showed relatively potent antiproliferative activites on HepG2 human
liver cancer cell growth.
29. 4.Naringin:
• Occurrence:
Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit
juice its bitter taste.
• Isolation:
The typical method featured methanol extraction followed by crystallization in
water.
Methanol was employed to extraction of fresh and dry albedo at room
temperature and under heating.
Each experiment repeated was 3 times.
30. • Characteristic features:
-Naringin provides the grape fruit its inherent characteristic bitter tatse.
-It may also increase the ability to ‘taste’ by direct stimulation of the taste-buds.
-Naringin particularly reduces LDL cholesterol content in blood, but without
affecting the HDL cholesterol.
-Naringin protects against the radiation-induced damage in the body to a great
extent.
-It also possesses antiapoptotic properties.
• Chemical nature:
Naringin
33. • Characteristic features:
-Quercetin is a ‘flavonol’ and usually found in high concentration in apple skin,
red onion, red grapes, green tea and buckwheat.
-It is usually does not suffer any ‘loss of content’ in drying grapes to raisins.
-Quercetin found to act as a blood thiner, and as a vasodialator.
-Quercetin evidently possesses sirtunin-like deacetylase activity.
• Chemical nature:
34. • Uses:
-Reduction in urinaray track infection
-Athroscerosis
-CVS disorder
-Ovarian cancer
• Health benefits:
-To reduce inflammation
-Eliminate pain
-Protect against cardiovascular diseases
-Act as an anti-cancer
-Boost the immune system
-Reduce histamines
-Decrease irritation of skin